... treat- ment and lung function in further prospective studies. Conclusions Our findings are in line with previous observations show- ing an inverse association between blood pressure and lung function. Furthermore, ... effects on lung function or respiratory symptoms [13,14]. However, these studies investigated the potential effect of BBL intake on lung function mainly in patients with already existing pulmonary ... allows only statements about a single point in time and does not allow evaluating the effect of long-standing high blood pressure. Another explanation for this lung function decrement could be that...
Ngày tải lên: 25/10/2012, 10:45
... Teachers talking time in speaking lessons’ The information obtained from Figure 6 indicates that teachers always take much time explaining in speaking lessons (70%). Only a small minority (10%) ... mother-tongued inference have bad influence on their involvement in English speaking lessons. 1.4. Teachers difficulties in teaching speaking in speaking lessons’ The result from the survey indicates ... difficulties in speaking lessons‘ As shown in Figure 5, 18% of the participants think that finding ideas for the given topic is one of difficulties deterring their involvement in speaking lessons,...
Ngày tải lên: 07/11/2012, 14:50
Tài liệu Date & Time doc
... set the date and time from within Terminal (Chapter 16 ). Use sudo (Section 16.7.5.1), type date yyyymmddhhmm.ss, and press Enter. (Of course, replace that code with the actual date and time you ... this time, and every email you send or receive is marked with this time. As you might expect, setting your Mac's clock is what the Date & Time pane is all about. 9.7.1. Date & Time ... accurate scientific clock on the Internet. (No need to worry about Daylight Saving Time, either; the time servers take that into account.) Tip: If you have a full -time Internet connection (cable...
Ngày tải lên: 21/01/2014, 04:20
Tài liệu White Matter Changes Compromise Prefrontal Cortex Function in Healthy Elderly Individuals docx
... Prefrontal cortex and episodic memory: Integrating findings from neuropscyhology and functional brain imaging. In T. B. Amanda Parker & E. Wilding (Eds.), Memory encoding and retrieval: A cognitive ... neigh- boring 64 grid points), we can obtain a finer anatomi- cal match than is achievable using linear or nonlinear globally parameterized transformations. The multigrid approach refers to using control ... determine the regional dorsal PFC WMH volume for each individual. fMRI Data Preprocessing and Spatial Normalization Functional imaging data were realigned in SPM99 and spatially normalized using in- house,...
Ngày tải lên: 14/02/2014, 07:20
Tài liệu Báo cáo khoa học: SREBPs: SREBP function in glia–neuron interactions pdf
... FEBS sion of SREBP-1 in the brain does increase in mice during aging [39], a phenomenon also observed in the peripheral nerve [3]. The meaning of this aging-related increase in SREBP-1 in both the PNS ... myelin protein-22, myelin asso- ciated glycoprotein (MAG) and myelin basic protein, but no myelin-specific lipids. Nevertheless, whereas all major lipid classes are present in myelin, as in other membranes, ... depletion of Lpin1 function in Schwann cells only is sufficient to induce a demyelinating phenotype [23]. Whether lipids from the epineurial compartment are implicated in functioning of axons and...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc
... VH2-N) which we previously showed does contain an actin- binding domain (this actin-binding domain has not yet been mapped) [23]. We name the actin-binding domain that we have identified VH2-C and VH2-N ... submodules in C-Vrp1p are required for actin-cytoskeleton polarization: a novel C-terminal actin-binding submod- ule (CABS) that contains a novel G-actin-binding domain, which we call a verprolin homology ... domains are directly implicated in polarization of the yeast actin cytoskele- ton. The presence of the novel actin-binding VH2-C domain in C-Vrp1p 364)817 may explain why mutations in the N-terminal...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress pdf
... additional insights into this interesting question. Conclusions In summary, we have identified a novel metabolic gene switch (decrease in fatty acid utilization, increase in glucose utilization) in the ... 2007) doi:10.1111/j.1742-4658.2007.06051.x The mechanisms underlying increased cardioprotection in younger female mice are unclear. We hypothesized that serine-threonine protein kinase (protein kinase B; Akt) triggers a metabolic ... prosurvival serine-threonine protein kinase, Akt (also known as protein kinase B) [2]. In agreement with this, elevated levels of activated Akt in female hearts are linked to improved cardiac cell...
Ngày tải lên: 18/02/2014, 16:20
Consultative document The internal audit function in banks pptx
... 2 nd line Risk management function, compliance function and other monitoring functions 3 rd line Internal audit function 56. Control failings by one line of defence should, in principle, ... 4 The internal audit function in banks 1. The internal audit function 8. The internal audit function plays a crucial role in the ongoing maintenance and assessment of a bank’s internal ... not interfere in its business decisions, it can be in a position to influence them by challenging management. Both the internal audit function and banking supervisors have an interest in the...
Ngày tải lên: 06/03/2014, 10:20
The internal audit function in banks docx
... responsibility for maintaining the function s independence and objectivity. 14. The internal audit function should not be involved in designing, selecting, implementing or operating specific internal control ... directors remains ultimately responsible for these activities and for maintaining an internal audit function within the bank. Outsourcing of internal audit activities is further addressed in principle ... identifying, measuring, assessing, controlling, responding to, and reporting on all the risks resulting from the bank’s activities; • the integrity of the risk management information systems, including...
Ngày tải lên: 06/03/2014, 10:20
Ecosystem Function in Heterogeneous Landscapes docx
... dynamic space, complex feedbacks, or nonlinearities in responses. These components require a more dynamic consideration of interacting elements. Interacting Elements An interacting element approach is required ... new understanding about ecosystem function in time and space. Looking Ahead Understanding spatial heterogeneity has been referred to as “the final fron- tier” in other areas within ecology (e.g., ... book, providing synthetic views of the problem and describing progress in developing overarching conceptual frameworks. Reference Shugart, H.H. 1998. Terrestrial ecosystems in changing environments....
Ngày tải lên: 06/03/2014, 18:21
Báo cáo khoa học: Amino acids Thr56 and Thr58 are not essential for elongation factor 2 function in yeast potx
... that the threonine at position 56 could be replaced by cystein, methionine and serine (Fig. 2). Mutants containing asparagine, aspartic acid, glycine, lysine or valine were nonfunctional (Fig. ... recombi- nation using LR clonase. The destination vector was trans- formed into strain YOR133w for confirming gene expression, and into strain GB1 for functional analysis by plasmid shuffling. A copy ... were unable to functionally complement wild-type eEF2) were able to bind to ribosomes in cells also expressing wild-type eEF2 from one of the remaining eEF2 coding genes. Because binding of eEF2...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Cholecystokinin rapidly stimulates CrkII function in vivo in rat pancreatic acini Formation of CrkII–protein complexes docx
... migrating band (lane 2), showing that it contains the more tyrosine phosphorylated band of Crk. Pretreatment with tyrosine kinase inhibitor alone increased the intensity of the lower migrating ... phosphotyrosine-containing proteins such as p130 Cas , paxillin or Cbl [10,12]. The first SH3 domain (N-terminal) of CrkII binds to guanine nucleotide exchange factors such as C3G, which in turn activate ... transduction cascades involving small GTP-binding proteins [10,12]. Recent investigations reported that CrkII complex formation is induced by oncogenes such as Bcr-Abl [13], integrins [14], growth...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo Y học: Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans doc
... Dystrophin–dystrobrevin interactions in C. elegans (Eur. J. Biochem. 269) 1611 Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans Karine Grisoni, Kathrin Gieseler ... reminiscent o f dystrophin (mdx ) mutations [10]. a-Dystrobrevin binds to dystrophin via a coiled-coiled motif present in both proteins, and to the PDZ domain containing syntrophins [11,12]. Indirect ... dystrobrevin binding to dystrophin and dystrobrevin function. Deletions of the dystrobrevin protein w ere performed and the ability of the mutated forms to bind t o dystrophin was tested both in vitro...
Ngày tải lên: 08/03/2014, 23:20
Reproductive System Structure, Development and Function in Cephalopods with a New General Scale for Maturity Stages pot
... male squid. Therefore, it seems inappropriate to include functional maturation and maturity in a single maturity stage (as in Zuev et al., 1985). The processes of formation of sexual products are different in their complexity and significance. How- ever, movement of mature sexual cells to different parts of the reproductive system ... of this class. In mollusks which lay their eggs in rigid capsules, capsule glands and albumin glands are pres- ent in a complex of pallial glands. These differ in their origin and function (Chukchin, 1984). Oviductal glands in octopus secrete ... ocean. Fecundity is low in squid inhabiting shelf areas where the bottom provides a stable substrate for egg laying. In reef-living Sepioteuthis, only 2 to 6 eggs are laid in a mucous string which is hidden...
Ngày tải lên: 14/03/2014, 16:20
Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... determinant behind its signaling capac- ity. The existence of a C-terminus domain (C-domain) emerged from a prediction of the 3D structure of a single-chain heparanase enzyme [73]. In this protein variant, ... modular structure [9]. Accumulating evidences indicate that HSPGs act to inhibit cellular invasion by promoting tight cell–cell and cell–ECM interactions, and by main- taining the structural integrity and self-assembly ... the seemingly distinct protein domains observed in the 3D model, namely the TIM-barrel and C-domain regions, mediate enzymatic and nonenzymatic functions of hep- aranase, respectively. Interestingly,...
Ngày tải lên: 15/03/2014, 23:20
Plug-In PHP: 100 Power Solutions: Simple Solutions to Practical PHP Problems pot
Ngày tải lên: 16/03/2014, 23:20