dangerousness risk and the prediction of probability

... main safeguards in place, and concludes that there may be a need to reconsider some of them in view of the growing role of nonbanks and of the global reach of risks in the electronic era Introduction ... the case in several European countries), compliance risk may arise if the rules and management of the payment scheme not comply with the regulatory standards • Risk of illicit use: the risk of ... The risk elements are then viewed in the context of other company-specific factors, such as the state of current control (i.e., the security baseline); the sophistication of vulnerabilities and...

Ngày tải lên: 18/10/2013, 17:15

... increase the number of novel drug targets and improve the approval rate of new drugs When thinking about the possible network representations of diseases, drugs and drug targets, the elements of the ... hydrophobicity and the ability to form hydrogen bonds, reduce further the number of drug candidates that can be given orally, which is the method normally desired [7] The analysis of the drug-target ... analysis and visual representation of drug-therapy and drug-target networks, the weight of the links (such as the number of drugs binding to both of two linked targets in the drug-target network) is...

Ngày tải lên: 06/08/2014, 18:21

... help professionals understand their patients' risk, and patients to understand their own risk Broadly these can be aggregated under the headings of perception (influences on how individuals and ... bleeding and cardiovascular events to provide a suitable and consistent context The background rate of events, the relative risk with NSAID or coxib, and the probability of dying could then be ... study was about whether using the test in the emergency room rather than elsewhere in the hospital was acceptable, given that it had a very small level of risk The trivial level of risk was presented...

Ngày tải lên: 09/08/2014, 10:23

... using the assumption of 100 % recovery of the gold element and of a 50 % recovery of the rest in the partially collateralised structure Calculate the risk premium by multiplying the probability of ... in the case of unsecured debt is then 50 % A check of the calibration of the calculations delivers the following: the total recovery equals 50 %; the annual likelihood of default is 16 %, therefore ... factors: the probability of default (PD), the expected unsecured recovery rate in the event of default and the collateral/guarantee recovery in the event of default The yield rate is modeled as: (risk...

Ngày tải lên: 01/11/2014, 12:17

... concerned about the default risk of the banks as they were about the default risk of Fannie and Freddie As we discuss toward the end of the chapter (when we consider the ‘‘too big to fail’’ theory as ... limit on the supply of the tranches that were most in demand the AAA tranches—because the starting points of the rating models were predictions of the rate of default on the entire pool Had the rating ... banks, the relevant laws were the Basel I accords of 1988, which were implemented in the United States in 1991 by the FDIC, the Federal Reserve, the Of ce of the Comptroller of the Currency, and the...

Ngày tải lên: 03/11/2014, 16:26

... Risk and Term Structure of Interest Rates • The risk structure of interest rates looks at bonds with the same term to maturity and different interest rates • The term structure of interest ... over the life of the long-term bond • Buyers of bonds not prefer bonds of one maturity over another; they will not hold any quantity of a bond if its expected return is less than that of another ... n The n-period interest rate equals the average of the one-period interest rates expected to occur over the n-period life of the bond Expectations Theory • Explains why the term structure of...

Ngày tải lên: 05/01/2014, 16:56

... 4) The R2 of the full model is 17.24%, i.e the combined contribution of the systematic factor and the regulation to the total timely variation of the exposure is 17.24% and, therefore, 82.76% of ... instance, the duration, and the weighted sum of the positions’ duration is a measure of the bank’s exposure to interest rate risk (See, for instance, Sierra and Yeager (2004)) The main problem of these ... correlation between the earnings from term transformation and the risk premia on loans In times of a boom the term structure tends to be steep and the risk premia (and thereby the mark-up) tend...

Ngày tải lên: 16/02/2014, 06:20

... or risk index Scope of risk G Scope of risk and details of possible events, including description of the events, their size, type and number Nature of risk G Classification of risk, timescale of ... rank the key risks for further analysis Risk classification systems An important part of analysing a risk is to determine the nature, source or type of impact of the risk Evaluation of risks ... 1: Risk, risk management and ISO 31000 Nature and impact of risk Principles of risk management Review of ISO 31000 Achieving the benefits of ERM Part 2: Enterprise risk management Planning and...

Ngày tải lên: 21/02/2014, 12:20

... occur is deferred to the last section because it involves a series of fairly lengthy constructions and is not needed for the proof of the other theorems The case R = of Theorem was done by Bell ... holds and so, case LC implies (c) Proof of Theorem Proof (of (a)): If R = 0, there is nothing to prove Otherwise, the hypothesis asserts that [xn ] C(x)2 ≤ [xn ] M C(x) for some M < ∞ and n sufficiently ... surface, B depends on the type of map, and A depends on both the type of map and the surface See [22] for a proof of (7) for the unrooted case and for further references Zvonkin [28, p 290] remarks...

Ngày tải lên: 07/08/2014, 06:20

... depression, and odor of acetone on the breath Endometritis was diagnosed weeks postpartum by examination by the authors and diagnosed by the presence of the following clinical signs: cloudy discharge and ... compared using the chi-square test Evaluation of the effect of retained placenta on the occurrence of reproductive and metabolic disorders Cows were grouped based on the occurrence of retained placenta ... during the warm season for the first lactation and during the cold season for the second lactation Cow parity and calving season were eliminated from the final model since they did not influence the...

Ngày tải lên: 07/08/2014, 18:21

... part of physicians and the public in understanding the inevitable competing risks and benefits of medical therapy and the inherent uncertainties in the current paradigm of drug development For the ... further confusion regarding the understanding of the overall relative risk to benefit of these therapies This ‘yo-yo’ reflects evolving science, diminished public tolerance of uncertainty and risk, ... treatment of arthritis and other causes of pain for the foreseeable future The past decades have witnessed multiple changes in the public’s risk perception of these drugs: a low risk of nonselective...

Ngày tải lên: 09/08/2014, 07:20

... Probability distributions of the Pfold model and Implications of the independence property Combined probability distributions of the Pfold model and theimplications of the independence property ... interaction Figure shows the alignment and joint secondary structure prediction of the OxyS-fhlA complex, i.e., the secondary structures of OxyS and fhlA and the interaction between them, as predicted ... description of the scoring of single-stranded positions However, they are scored the same way as in the original PETfold approach; for more details, see [25] The PETfold score is the sum of the evolutionary...

Ngày tải lên: 12/08/2014, 17:20

... infrastructures of their institutions, and of the risk profiles and logistics of the whole production line These issues are very difficult to address in a multicentre trial without far-reaching standardisation ... on the use of central venous saturation, it is advisable to ensure that the predictive value of central venous saturation in the participating centres and in their case mix remains, and that the ... context of the specific institutions where they are performed The risks associated with surgery are multifactorial, and the same high -risk criteria applied in different institutions and to different...

Ngày tải lên: 12/08/2014, 23:20

... studies, and for the interactions of these factors means a greater proportion of the unexplained variation can be accounted for – increasing the power of the meta-analysis Other advantages of individual ... / total number of patients) in patient groups taking Drug (dark lines) and Drug (light lines) OA and OC represent the results of one trial, and AB and CD the other trial OA has the lesser slope, ... effects in a single nonrandomised trial, such as that in Table Here OA and OC represent results from one stratum of the trial, and AB and CD the other When the confounding effect of stratum is ignored,...

Ngày tải lên: 13/08/2014, 11:22

... loan product— the pick and pay mortgage loan The borrowers pick the amount of the loan, the term of the loan, and what they want to pay each month The repayments selected stay at the agreed level ... as one of Time’s 100 most influential figures of the twentieth century, John Maynard Keynes was the author of General Theory of Employment, Interest, and Money and one of the fathers of modern ... Government mandarins and academics vouchsafe the contribution of finance to society at large Bankers talk of innovation and the golden age of finance, the money to be made, and the money they are...

Ngày tải lên: 03/11/2014, 18:42

... and customer is that of debtor and creditor But quoad the drawing and payment of the customer’s cheques as against the money of the customer’s in the banker’s hands the relationship is that of ... 1.2 Thesis Structure 1.3 Overview of the Singapore Legal System 1.4 Overview of the Customer’s Duty of Care 1.5 Overview of the Bank’s Duty of Care 1.6 Interaction of the Two Duties 1.7 The Express ... Court and the Court of Appeal The Court of Appeal is the highest court in the country since the abolition of rights of appeal to the Privy Council This was achieved in stages,20 culminating in the...

Ngày tải lên: 11/09/2015, 09:11

... minimum of the other years 134 Figure 6.2 The number of hourly instances that the horizontal global radiation for each month of the year exceeds the maximum or falls below the minimum of the other ... of the year falls below the minimum of the other years 135 Figure 6.5 The cumulative amount by which the horizontal global radiation for each month of the year exceeds the maximum of the ... properties Thermal properties of construction materials, which affect the rate of heat transfer in and out of a building and consequently the indoor thermal conditions and comfort of the occupants,...

Ngày tải lên: 14/09/2015, 13:58

... to validate their hypothesis on the cost of debt: results indicate that the higher the level of ERM in a firm, the higher the cost of debt Because their hypothesis about the cost of debt is unsupported, ... empirically, and the rationale for choosing them The first hypothesis is based on the study of indirect environmental risks and agency CORPORATE ERM AND THE COST OF DEBT FLORENT ROSTAING 2009 problems The ... Sharfman and Fernando and the potential flaws in it I now focus on the treatment that Sharfman and Fernando use to test the specific correlation between ERM and the cost of debt They start their...

Ngày tải lên: 03/10/2015, 21:58

... factors and the monthly idiosyncratic risk of the REIT is the standard deviation of the regression residuals of the previous month 3.2.4 Random Walk Tests of Market Risk and Idiosyncratic Risk As ... is the value of the current period However, it is not appropriate for the market risk and idiosyncratic risk of the REITs Table presents the results of the random walk tests of market risk and ... portfolios according to their estimated idiosyncratic risk in the previous month They then compare the risk- adjusted returns between the highest risk and lowest risk portfolios and found the difference...

Ngày tải lên: 09/10/2015, 11:06

... JM and SL contributed to the conception and design of the review JM and DS contributed to the literature searching, data extraction and analysis JM and SL drafted the article and DS revised the ... levels of complexity of ip t a task of the same nature (reciting the alphabet and reciting alternate letters of the alphabet) were used For these studies, only gait speed data recorded in the most ... event in which the participant unintention ally came to rest on the floor or ground, regardless of the cause or the consequen ces of the fall" “loss of balance resulting in landing on the floor or...

Ngày tải lên: 25/08/2016, 23:09