culture cognition and evolution

... Albright and Helen J Neville li Computational Intelligence, Michael I Jordan and Stuart Russell Linguistics and Language, Gennaro Chierchia lxxiii xci Culture, Cognition, and Evolution, Dan Sperber and ... 278 Epistemology and Cognition 280 Essentialism 282 Ethics and Evolution 284 Ethnopsychology 286 Ethology 288 Evolution 290 Evolution of Language 292 Evolutionary Computation 293 Evolutionary Psychology ... Jordan and Stuart Russell) Linguistics and Language (Gennaro Chierchia) Culture, Cognition, and Evolution (Dan Sperber and Lawrence Hirschfeld) These editors advised us regarding both the topics and...

Ngày tải lên: 11/04/2014, 10:36

... of primary and secondary amines (sarcosine, N-ethylglycine, and glycine) and d-amino acids (d-alanine and dproline), yielding the corresponding a-keto acid, ammonia or primary amine and hydrogen ... connecting helices a1 and a2, and loop 130, spanning strands b6 and b7 Eight amino ˚ acids interact directly (< A) with GriP: the majority of contacts are made between charged groups, and these include ... domain colored pale green and the C-terminal domain colored brown The helix containing Pro101 is colored magenta, and the S3P and glyphosate molecules are colored green and yellow, respectively...

Ngày tải lên: 14/02/2014, 14:20

... ⁄ and the PI3K ⁄ Akt pathways results, in turn, in the inactivation of pro-apoptotic Bcl-2 proteins (e.g PUMA, Bax, Bim and Bad), Fas, and CDK inhibitors (e.g p27KIP1, p21WAF1 and p15INK4b), and ... both cell proliferation and survival Potential targets of these MAPK and PI3K ⁄ Akt signaling pathways include apoptosis-related molecules (Bcl-2 family members and Fas) and cell-cycle regulatory ... Takeuchi and F Ito 21, and PC-9, harboring a deletion (del746-750) in EGFR exon 19, are highly sensitive to gefitinib; and this sensitivity to gefitinib is associated with dependence on both Akt and...

Ngày tải lên: 16/02/2014, 09:20

... the recognition process At first, we synthesized two peptides [NarG(1–15) and NarG(1–28)] and solved their structures by NMR; NarG(1–15) corresponding to the predicted N-terminal helix and NarG(1–28), ... ± 0.2 and a binding constant (Kd) of 3.4 ± · 10)9 m and a second with a stoichiometry of 0.7 ± 0.1 and a Kd of 3.3 ± · 10)7 m (Fig 5A) Identical results were obtained using NarJ or NarJT and both ... for peptide recognition by NarJ A B Fig (A) Sequences of NarG(1–15) (left) and NarG(1–28) (right) and sequential assignments Collected sequential NOEs are classified into thick and thin bars according...

Ngày tải lên: 16/02/2014, 14:20

... psychobiology, and cognition In: The Foundations of Aesthetics, Art, and Art Education, Farley, F and Neperud, R (Eds) Praeger, New York, USA Martindale, C and Moore, K (1988) Priming, prototypicality, and ... Scott, J D., Moulder, B and Nangia, V (1998) Emotional arousal and activation of the visual cortex, and fMRI analysis, Psychophysiology 35, 199–210 Leder, H (2005) Art and cognition! Consequences ... qualities, and modification (Bernard, 1972; Cela-Conde et al., 2002; Furnham and Walker, 2001; Hekkert and van Wieringen, 1996a, 1996b; Johnson and Knapp, 1963; Lindauer, 1990; Neperud, 1986; Winston and...

Ngày tải lên: 19/02/2014, 17:20

... things that were to be and that were, and all things that are not now, and that are, and this revolution in which now revolve the stars and the sun and the moon and the air and the ổther that are ... but in our case, and in relation to ourselves, Sensation is first, and of Sensation and Understanding the essence of knowledge is formed, and evidence is common to Understanding and Sensation."[52] ... existence and attributes of God, were but "portions" and "fragments" true and trustworthy so far as they went, and from their own particular standpoint, but, nevertheless, essentially and necessarily...

Ngày tải lên: 21/02/2014, 08:20

... object to the concept of randomization and many investigators feel that randomization, in of it itself, is unethical (5) Randomization requires that the investigator and the subject consider themselves ... Ranking and Selection Designs Designs for ranking and selection procedures are often helpful and generally require a smaller sample size than randomized controlled trials (8) In ranking and selection ... pulmonary nodules (

Ngày tải lên: 05/03/2014, 23:20

... curiosity and to our dedicated families for their love and support —J R L and P S v In Memorium In memory of Carlos A Garcia (1935–2005) and his passion for medicine, science, and the patients and ... proceeded to stand, look at both Dr Garcia and I, and stated, “I am going to go get a REAL doctor” and proceeded to the emergency room next door Needless to say both he and she were just fine and Dr ... Willard and M Katharine Rudd PART III GENOME EVOLUTION Primate Chromosome Evolution 133 Stefan Müller 10 Genome Plasticity in Evolution: The Centromere Repositioning 153 Mariano Rocchi and...

Ngày tải lên: 05/03/2014, 23:20

... CDRs of heavy chain and CDR3 of light chain [ref 39] Fv Randomization in CDR loops of heavy and light chains Y/S library in BC, DE and FG loops 10 FN3 Randomization in BC, DE and FG loops Fig Local ... proteins, and the first and second minireviews focus on the detection of protein–protein interactions [8,9] In this third minireview, we focus on the molecular evolutional methodology for generating and ... (XGGGS)n in which the X residues were randomized and the linker length (n) was intermittently varied (B) DARPin: six amino acids in the loop and helix structures are randomized (C) A-domains: variable...

Ngày tải lên: 06/03/2014, 11:20

... [35S]methionine and incubated further in the absence (lanes 1, 2, 5, 6, and 10) or presence (lanes 3, 4, 7, 8, 11 and 12) of phosphatidylinositol-specific phospholipase C Both cell lysates (C) and media ... England Nuclear (Boston, MA, USA); and 14C-methylated proteins and the enhanced chemiluminescence (ECLÒ) western blotting detection reagent, peroxidase-conjugated donkey anti-(rabbit IgG) and ... protein and the mutant protein were partitioned into a cold Triton X-100-insoluble fraction (the raft) at a similar rate (Fig 3B), further supporting that the folding and assembly process and subsequent...

Ngày tải lên: 07/03/2014, 05:20

... clustering methods and the linguistic interpretation of the resulting classes References Anna Babarczy, B´ lint G´ bor, G´ bor Hamp, Andr´ s a a a a K´ rp´ ti, Andr´ s Rung and Istv´ n Szakad´ ... of Verb Frames and Verb Classes from Corpora Corpus Linguistics An International Handbook., Anke L¨ deu ling and Merja Kyt¨ (eds) Mouton de Gruyter, Berlin o Suzanne Stevenson and Eric Joanis ... USA D´ Csendes, J´ nos Csirik, Tibor Gyim´ thy and Andr´ s o a o a Kocsor 2005 The Szeged Treebank LNCS series Vol 3658, 123-131 Bonnie J Dorr and Doug Jones 1996 Role of Word Sense Disambiguation...

Ngày tải lên: 08/03/2014, 03:20

... precision, recall, and F-scores on the chunking-function-tagging task, with standard deviation, using the input features words, attenuated words, gold-standard POS, and MBT POS, and combinations, ... (Stanfill and Waltz, 1986; Cost and Salzberg, 1993) (3) was set to seven This and the previous parameter setting turned out best for a chunking task using the same algorithm as reported by Veenstra and ... precision, recall and their harmonic mean, Our total data set consists of all 74,024 sentences in the Wall Street Journal, Brown and ATIS Corpus subparts of the Penn Treebank III We randomized the...

Ngày tải lên: 08/03/2014, 07:20

... in three cue and association frequency bands these frequency bands With respect to cue frequency, the word space models and compounding approach suffer most from low frequencies and hence, data ... are the word-based distributional models with and without a stoplist (highest medians at 11 and 12, highest means at 30.9 and 33.3, respectively), and then the syntax-based word space model (median ... all the associations in a set of candidate associations, and complemented it with 1000 random words from the corpus with a frequency of at least 200 From these candidate words, we had each model...

Ngày tải lên: 08/03/2014, 21:20

... nucleotide and the 3’ carbon of the sugar of another nucleotide This bond is very strong, and for this reason DNA is remarkably stable DNA can be boiled and even autoclaved without degrading! 5’ and ... studies of Erwin Chargaff • indicated double-stranded DNA consists of ~50% purines (A,G) and ~50% pyrimidines (T, C) • amount of A = amount of T and amount of G = amount of C (Chargraff’s rules) ... resulting in major and minor grooves 1962: Nobel Prize in Physiology and Medicine James D Watson Francis H Maurice H F Crick Wilkins What about? Rosalind Franklin RNA (A pairs with U and C pairs with...

Ngày tải lên: 13/03/2014, 16:34

... nucleotide and the 3’ carbon of the sugar of another nucleotide This bond is very strong, and for this reason DNA is remarkably stable DNA can be boiled and even autoclaved without degrading! 5’ and ... studies of Erwin Chargaff • indicated double-stranded DNA consists of ~50% purines (A,G) and ~50% pyrimidines (T, C) • amount of A = amount of T and amount of G = amount of C (Chargraff’s rules) ... resulting in major and minor grooves 1962: Nobel Prize in Physiology and Medicine James D Watson Francis H Crick Maurice H F Wilkins What about? Rosalind Franklin RNA (A pairs with U and C pairs with...

Ngày tải lên: 13/03/2014, 17:04

... is a b-sandwich, containing a five-stranded sheet and a b-hairpin (both of which are anti-parallel) The third domain is a b-sandwich composed of one fourstranded sheet and one three-stranded sheet, ... structures and properties of these domains The second and third domains of e-toxin exhibit obvious structural similarity to the third and fourth domains of aerolysin, and to the second and third ... [33], leading to pore formation, an efflux of K+ and an influx of Na+ and Cl) ions [35] In addition, cytotoxicity is temperature- and pH-dependent [36] and is potentiated by EDTA [37] Recently, the...

Ngày tải lên: 14/03/2014, 22:20

... discuss molecular recognition in these receptors; this means the structural basis for affinity and specificity And, third, we will see how the accumulated data on structure and mechanism aid in ... dimeric ligand [11,12] This can lead to avidity effects, where ligand affinity is increased by binding simultaneously to two receptor chains The formation of heterodimeric ligands and ⁄ or multiple ... ligand with membrane receptor chains provide new opportunities for a cell to determine and tune receptor affinity and, therefore, specificity Combinatorial assemblies of heterodimeric BMPs and...

Ngày tải lên: 15/03/2014, 09:20

... would be right and praiseworthy, and others wrong and worthy of condemnation; even there Doctors and patients and their relatives would have certain rights and duties In such a land, the lecturer ... and likeness; and let him have dominion over the fishes of the sea, and the fowls of the air, and the beasts, and the whole earth, and every creeping creature that creepeth upon the earth.” And ... food and clothing, his mental and physical improvement, and even his reasonable recreations Man can lawfully hunt and fish and practise his skill at the expense of the brute creation, notwithstanding...

Ngày tải lên: 15/03/2014, 13:20

... EhPGK, and green refers to pig PGK and EhPGK Thus, in order to determine the role of Y239, E309 and V311 on the GDP ⁄ GTP preference of EhPGK, the single mutants Y239F, E309M, E309Q and V311L, and ... adenine base in pig PGK (upper) and guanine base in modeled EhPGK (down) were calculated and represented with MOE Shadows represent solvent accessibility of ligand atoms and protein residues Hydrogen ... group with the recombinant purified enzyme, where Km values for ADP and ATP were 12 and 44 times higher than the Km values for GDP and GTP, respectively [4] To our knowledge, the higher selectivity...

Ngày tải lên: 16/03/2014, 01:20

... intensity of the bands for the protein and the mRNA were faint Effects of inhibitors of cGCS and GR on primary cultured testicular cells To investigate the contribution of de novo synthesis and the recycling ... concentrations of total glutathione and GSSG were calculated from the absorbance change using authentic GSH and Ó FEBS 2002 1572 T Kaneko et al (Eur J Biochem 269) GSSG as a standard and the data are expressed ... deferens, and prostate gland in 13-week-old-adult rats (Fig 1A) The highest activity for GR was found in the epididymis, followed by seminal vesicles, prostate gland, vas deferens, and testes...

Ngày tải lên: 17/03/2014, 17:20