crp and high sensitivity c reactive protein hs crp

... (0.47-1.07) hs -CRP mg/l 0.99 (0.98-1.01) CAD, coronary artery disease; ECG, electrocardiogram; hs -CRP, high sensitivity C reactive protein Diercks et al International Journal of Emergency Medicine 2011, ... ratio) and diagnostic test characteristics determined Sensitivity, specificity, and likelihood ratios were calculated and 95% confidence intervals (CI) presented for local laboratory hs -CRP thresholds ... Emergency Medicine 2011, 4:37 http://www.intjem.com/content/4/1/37 0.00 0.25 0.50 - Specificity 0.75 1.00 Area under ROC curve = 0.4969 Figure ROC curve for the diagnostic accuracy of hs -CRP CRP...

Ngày tải lên: 21/06/2014, 02:20

... index; CRP = C- reactive protein; CV = coefficient of variation; hsCRP = high sensitivity CRP; IL = interleukin; ln = natural log; OA = osteoarthritis; RA = rheumatoid arthritis; SD = standard ... asymptomatic women at mid-life As the evaluation of the direct relationship between hsCRP and knee cartilage is potentially complicated by the concurrent relationships between CRP and increased ... malignancy or cancer treatment, excluding non-melanotic skin cancer All participants provided a detailed medical history in response to specific questioning and those with an active medical condition...

Ngày tải lên: 09/08/2014, 10:23

... septic condition and trauma influence CRP blood levels in children Hence, comparison of CRP and other proinflammatory markers such as PCT can be difficult because of their different kinetics and ... additional increase of CRP in surgical patients indicates that another factor influences CRP production With respect to our findings, traumatic insult or surgical intervention may cause increased CRP ... curves Predicted C- reactive protein (CRP) level curves of (left) model A and (right) model B ▲, Noninfectious group; ■, septic group; and curves ●, shock and multiple organ dysfunction syndrome...

Ngày tải lên: 13/08/2014, 03:21

... sandwich hsCRP ELISA a) by Comparisondifference values commercial CRPspiked carried Comparison of CRP concentration found for spiked serum samples obtained by the direct sandwich CRP assay carried ... sandwich test channel (❍); direct capture assay test channel (ᮀ); direct sandwich test channel ( ); homogenous sandwich control channel (x); direct capture control channel (+); direct sandwich ... CRP levels as a predictive test for CHD is now well documented and various hsCRP assays have been developed to monitor CRP Figure Direct Sandwich CRP assay carried out using RAP (n = 3) Direct...

Ngày tải lên: 11/08/2014, 00:22

... Chronic Health Evaluation; PCT, procalcitonin; CRP, C- reactive peptide Figure Plasma concentrations of the corresponding C- reactive protein (CRP) concentrations of patients within four categories ... survivors and non-survivors (Table 2) SOFA score: comparison with PCT and CRP For all patients observed, PCT and CRP concentrations within the four groups of increasing categories of the SOFA score ... Diagnostica GmbH, Berlin, Germany) and CRP by the ‘Turbi-Quanti’ method (Behring, Marburg, Germany) Statistics The correlations between the SOFA score and CRP and PCT concentrations were calculated...

Ngày tải lên: 12/08/2014, 18:20

... hepatocyte-stimulating factor Proc Natl Acad Sci USA 2000, 97:10144-10149 Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F: C- reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 ... Adolescents and Adults [42], which classifies patients on the basis of clinical conditions associated with HIV infection and CD4+ T- lymphocyte counts Clinical status and the CDC classification ... for Adolescents and Adults Based on clinical categories; category C includes the clinical conditions listed in the AIDS surveillance case definition CDC Classification System & Expanded AIDS...

Ngày tải lên: 12/08/2014, 23:23

... bacterial community-acquired pneumonia for C- reactive protein (CRP) and procalcitonin (PCT) No difference was detected in the discriminative value between CRP and PCT had positive urinary pneumococcal ... significant positive correlation was detected between the CRP and PCT concentrations (r=0.648, p=0.01) Diagnostic accuracy for discriminating TB from bacterial CAP In the ROC curve analysis, the CRP ... 100.0 PCT, ng/mL Values are presented as percentages Figure C- reactive protein (CRP) and procalcitonin (PCT) concentration according to the pneumonia severity index in bacterial community-acquired...

Ngày tải lên: 22/03/2014, 18:20

... DB, Clancy CM Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy JAMA 2003;290:1624-32 Copyright © 2007 Massachusetts Medical ... Clinical application of C- reactive protein for cardiovascular disease detection and prevention Circulation 2003; 107:363-9 Ridker PM, Hennekens CH, Buring JE, Rifai N C- reactive protein and other ... lowering, including reductions in the levels of C- reactive protein (CRP) , a phenomenon commonly termed a “pleiotropic effect.”4-6 In both recent comparisons, at the conclusion of the trials, CRP levels...

Ngày tải lên: 27/06/2014, 00:20

... Table CRP and NT-PBNP values for ischemic and hemorrhagic stroke VALUES CRP- Baseline CRP- 48 hours CRP- Discharge NT-PBNP-Baseline NT-PBNP-48 hours NT-PBNP-Discharge FIGURE ROC curve of the CRP baseline ... after acute ischemic stroke J Neurol Sci 2005; 236: 65-71 19 Masotti L, Ceccarelli E, Forconi S, Cappelli R Prognostic role of C- reactive protein in very old patients with acute ischemic stroke ... Paffen E, DeMaat MP C- reactive protein in atherosclerosis: A causal factor? Cardiovasc Res 2006; 71: 30-39 24 Yip HK, Sun CK, Chang LT, Chen MC, Liou CW Time course and prognostic value of plasma...

Ngày tải lên: 08/08/2014, 16:23

... the bacterium C- reactive protein (CRP) is an acute-phase reactant that originates from the liver CRP has many clinical and biological effects and can be used for the diagnosis and follow-up of ... et al C- reactive protein, the metabolic syndrome and risk of incident cardiovascular events Circulation 2003; 107: 391–7 Russell PT, Rozenn NL, Bruce MP, et al Relationship of C- reactive protein ... distributed symmetrically with one peak Participants with hsCRP more than 0.1 mg/dl were defined as high hsCRP individuals in this study The proportion of high hsCRP subjects was compared between...

Ngày tải lên: 08/08/2014, 17:20

... CRP and the characteristics of breast tumour (A) CRP levels according to tumor depth (B) CRP levels according to LN metastasis (C) CRP levels according to distant metastasis (D) CRP levels according ... metastasis Clinicopathological significance of CRP Table Correlation between the IL-6, CRP and clinicopathological parameters IL-6 Median ± SD Total CRP r P pg/ml Median ± SD R P We noted that CRP levels ... 0.061) Figure shows (A) CRP levels according to tumor depth (B) CRP levels according to LN metastasis (C) CRP levels according to distant metastasis (D) CRP levels according to TNM staging 15.5...

Ngày tải lên: 09/08/2014, 01:24

... twice prior to incubation with FITC -CRP Fluorescence was analysed on an Coulter Epics XL flow cytometer (Beckman Coulter, High Wycombe, UK) and/ or a BD FACSCalibur flow cytometer Immunofluorescence ... neutrophils were incubated with FITC -CRP and sorted in a fluorescence-activated cell sorter (FACS) Light microscopic examination of both cell populations confirmed that the CRPhigh cells were "ghosts" ... precise role for CRP remains to be elucidated 13 Abbreviations 14 CFDA, 5-chloromethylfluorescein diacetate; CRP, C- reactive protein; FACS, fluorescence-activated cell sorter 12 15 Competing interests...

Ngày tải lên: 11/08/2014, 08:21

... 10 nM of each of the following primers: a target protein specific primer (5'-CCACCCACCACCACCAatgnnnnnnnn nnnnnnnn-3'; lowercase indicates the 5'-coding region of the target gene) and the AODA2306 ... requires many time-consuming steps such as vector construction, cell culture and purification to obtain the recombinant protein In contrast, this cellfree based luminescence method could analyze a ... Promoting Science and Technology by the Ministry of Education, Culture, Sports, Science and Technology, Japan (T S and Y E.) We thank Michael Andy Goren for proofreading this manuscript References 10...

Ngày tải lên: 12/08/2014, 03:20

... antibodies, CRP interacts with cellular Fcγ receptors, thereby facilitating the phagocytic clearance of circulating opsonized material Activation of the classical complement pathway is considered ... immunofluorescence and electron microscopy The biopsies were graded according to a standardized semiquantitative histological scoring protocol for activity and chronicity indices [31] Renal disease activity ... enhance binding of circulating soluble immune complexes to phagocytic Fcγ receptors [12,43] and constitute a vicious circle Conclusions We have demonstrated a statistically significant correlation between...

Ngày tải lên: 12/08/2014, 11:22

... (SOFA) score and severity of systemic inflammation according to American College of Chest Physicians/Society of Critical Care Medicine (ACCP/SCCM) criteria SOFA PCT (ng/ml) CRP (mg/l) Lactate (mmol/l) ... such as BT and WBC count may be unspecific Other parameters such as C- reactive protein (CRP) and procalcitonin (PCT) have been considered to evaluate the evolution of infections and sepsis in critically ... respective curve were calculated The maximum PCT and CRP concentrations, the maximum SOFA score and sepsis score in the first 24 hours (T1) were used to calculate the ROC curves Among the PCT, CRP, lactate...

Ngày tải lên: 12/08/2014, 20:20

... http://ccforum.com/content/10/1/R1 Figure and C- reactive protein maximum concentrations of procalcitonin (PCT) Histogram of the day of (CRP) in multiple-trauma patients and C- reactive protein (CRP) ... procalcitonin a 21-day trauma, and reactive protein (CRP) complications during (PCT) (0–48 hours) the Initial serum concentrations ofhours) after mechanical follow-up and Creactive protein (CRP) ... fractures according to accepted standards of care PCT, CRP, all clinical, microbiological, and laboratory data, and all diagnostic and therapeutic options were registered The data analyzed included...

Ngày tải lên: 12/08/2014, 23:20

... 0.01) Receiver-operating characteristic (ROC) curves comparing procalcitonin (pct), lipopolysaccharide-binding protein (lbp), C- reactive protein (crp) , IL-6 (il6), white blood cell (wbc) and neutrophil ... noninfected patients and all infected patients (P < 0.05) Receiver-operating characteristic (ROC) curves comparing procalcitonin (pct), lipopolysaccharide-binding protein (lbp), C- reactive protein ... characteristic (ROC) curves comparing procalcitonin (pct), lipopolysaccharide-binding protein (lbp), C- reactive protein (crp) , IL-6 (il6), white blood cell (wbc) and neutrophil (neutro) discriminating...

Ngày tải lên: 12/08/2014, 23:23

... 0.78 aSensitivity and specificity of C- reactive protein (CRP) , procalcitonin (PCT) and neutrophil count were computed using the predefined cutoff values of 60 mg/l, 0.25 μg/l and 7.5 × 109 cells/l, ... and organ failure and guidelines for the use of innovative therapies in sepsis The ACCP/SCCM Consensus Conference Committee American College of Chest Physicians/Society of Critical Care Medicine ... diagnostic accuracy Because we used clinical criteria and microbiological evidence, it might have been difficult to ascertain the precise cause of SIRS in all patients, and this might have introduced...

Ngày tải lên: 13/08/2014, 03:20

... American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee to define a non-specific generalized inflammatory process independently from any causative factor ... sepsis and may increase postoperative mortality and morbidity [4] Existing biological markers such as C- reactive protein (CRP) and procalcitonin (PCT) have been studied after CPB [5,6] Serum CRP ... that can accurately discriminate between SIRS and sepsis in this setting Existing biological markers such as CRP and PCT have been studied after CPB [5,6] Serum CRP values are not specific and...

Ngày tải lên: 13/08/2014, 19:20

... fibrinolytic system in severe sepsis Abbreviations AUC: area under curve; CFT: clot-formation time; CI: confidence interval; CRP: C- reactive protein; CT: clotting time; MCF: maximum clot firmness; ROC curve: ... without severe sepsis Procalcitonin, interleukin 6, and C- reactive protein concentrations were tested for differences between patients with and without sepsis Procalcitonin concentration averaged ... thrombosis and multiple organ dysfunction syndrome Crit Care Med 2010, 38:S35-S42 Ganter MT, Hofer CK: Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation...

Ngày tải lên: 13/08/2014, 21:21