counterfactuals of the past and potential outcomes of the future
FACING THE REALITY OF DRUG-RESISTANT TUBERCULOSIS: CHALLENGES AND POTENTIAL SOLUTIONS IN INDIA pot
... 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute ... become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and ... Commissioner at the time, Margaret Hamburg, drew upon the strong political will of the mayor and others to gather resources and mobilize a comprehensive response to the resurgence of TB in the city The city...
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Retail Consolidation and Produce Buying Practices: A Summary of the Evidence and Potential Industry and Policy Responses pot
... that these fees are necessary to help share the risk of the potential failure of a product, to pay for the cost of re-shelving, or simply to share the cost of promotion, the imposition of such ... for competition If offered by suppliers, then the potential for competitive foreclosure and raising of barriers to entry is clear On the other hand, much of the empirical and anecdotal evidence ... tools to address the imbalance of power in the produce industry? Unfortunately, there have been few systematic studies of their performance Central was the grandfather of the breed of cooperatives...
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Accelerating Equitable Achievement of the MDGs Closing Gaps in Health and Nutrition Outcomes potx
... secondary and tertiary education On health, it has begun to reduce the prevalence of HIV and has stopped the spread of tuberculosis And on the environment, it has increased the proportion of land area ... between the curve and the equal distribution line – expressed as a proportion of the whole area below the equal distribution line The higher the Gini index the greater the disparities Another measure ... on and off track for the MDGs Table I-2 Countries on and off track for the MDGs Table I-3 Rate of progress needed for off-track countries to meet the child nutrition target Table I-4 Rate of...
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Báo cáo khoa học: Contributions to catalysis and potential interactions of the three catalytic domains in a contiguous trimeric creatine kinase doc
... and a threedomain adenylate kinase [24] The present study provides insight into the inter-dependent functional properties of the three domains of FlgCK, and lays the groundwork for study of the ... in the dimer [15] In contrast, the recently published crystal structure of the TSAC of rabbit muscle CK [6] (and the TSAC structure for Torpedo [5]) is highly asymmetrical, with only one of the ... study of the relationship between these functional properties and the structural interactions that potentially mediate them Analysis of the primary structures of the three FlgCK domains Two CK TSAC...
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Báo cáo khoa học: The mystery of nonclassical protein secretion A current view on cargo proteins and potential export routes pdf
... overexpression of the a subunit interferes with FGF-2 export [68], these observations are reasonably supportive of a role for the Na-K-ATPase in the overall process of FGF-2 export On the other hand, ouabain ... activators of tumor-induced angiogenesis [45] The majority of the members of the FGF family are exported by ER/Golgidependent secretory transport However, FGF-1 and the 18 kDa isoform of FGF-2 ... associated with the outer leaflet of the plasma membrane only in the infectious stages of the parasite lifecycle [101,102] The protein is synthesized on free ribosomes in the cytoplasm and becomes...
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Internal Audit 2012*: A study examining the future of internal auditing and the potential decline of a controls-centric approach docx
... business and accounting And in the United States, the internationalization of accounting standards may lead to a change in the language of accounting • The growth of outsourcing and an upsurge in the ... areas of risk • Anticipate the needs of the audit committee and senior management • Identify emerging trends and bring them to the attention of key stakeholders • Strengthen risk coverage of technology, ... gave the highest priority to the areas of technology and risk management At the same time, 22 percent of respondents believe that the number of professional staff will remain about the same, and...
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Báo cáo khoa học: Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract pdf
... cells of pylorus (Fig 3G) Therefore, in the surface epithelium, ADH1 and ADH4 only overlapped in the gastric region close to the pylorus The endothelium lining small blood vessels within the gastric ... microbial flora, and products of lipid peroxidation [12,13] ADH4, located in the upper part of the gastrointestinal tract and the luminal part of the mucosa, would be in contact with the highest concentrations ... the Direccion General de Investigacion Cientı´ fica (BMC2002-02659 and BMC2000-0132) and the Commission of the European Union (BIO4-CT97-2123) to X P and J F., and by the National Institutes of...
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Improving Women’s Health and Perinatal Outcomes: The Impact of Oral Diseases ppt
... bacteria match that of their mothers’ in over 70% of the cases.5 One study has shown that the utilization of therapeutic mouth rinses beginning in the sixth month of pregnancy and continuing until ... diseases are capable of stimulating the excessive production of these physiological mediators, potentially resulting in preterm birth.31 The role of prostaglandins and cytokines in the link between ... adolescent and young adult women.13 The potential consequences of chronic eating disorders include the erosion of tooth enamel; enlargement of the salivary glands; xerostomia (dry mouth); trauma to the...
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The Past and Future History of the INTERNET potx
... the U.S.) Such was the weight of the NSFNET program’s COMMUNICATIONS OF THE ACM February 1997/Vol 40, No 105 ecumenism and funding ($200 million, 1986–1995) and the quality of the protocols themselves ... specifications of the protocols The beginnings of the ARPANET and the Internet in the university research community promoted the academic tradition of open publication of ideas and results However, the normal ... of the Internet program at DARPA, he and Clark recognized that the continuing growth of the Internet community demanded a restructuring of the coordination mechanisms The ICCB was disbanded and...
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under a green sky - global warming, the mass extinctions of the past, and what they can tell us about our future
... emptily down on the flowers and science pilgrims alike One of them was crucial in founding the science of stratigraphic geology and extinction In one of the halls near the edge of the park there is ... loudest dissent and opposition came To the others in the fossil fields, however, the evidence that there had been these die-offs in the past seemed overwhelming But what were the causes of these events? ... (volume) of them seemed to closely correspond in age to the times of each of the great mass extinctions of the last 500 million years The largest flood basalt of all, named the Siberian Traps (and they...
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Báo cáo hóa học: " Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032" potx
... PLX4032 As part of the eligibility requirements of the trial, paraffin-embedded tissue from a biopsy of a cutaneous lesion was tested and shown to be positive for the BRAF V600E mutation The patient ... writing of the manuscript; DN, excised tumors and provided the material for research; RH, in charge of analyzing tumor specimens and participated in writing the manuscript All authors have read and ... although the assay methodology used for the trial may not discriminate between the V600E and V600K mutations Our preclinical data demonstrating similar kinase activity of the V600K and V600E...
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Báo cáo khoa học: "Nutrient cycling in deciduous forest ecosystems of the Sierra de Gata mountains: aboveground litter production and potential nutrient return" pot
... selected; b) its potential return; and c) a comparison of the results from the chestnut coppice and the oak stands time of 3.1 Litter production In the study forests, the length of the biological ... revised and, N Skinner and D Garvey of the forests certain extent, are regulated by the chemical characteristics of the litter to a the main vector of the of bioelements to the A h horizon in all the ... of the fruits is greater than that of Fe, and that of Cu is greater than that of Zn in the other plant remains The general sequence of the amount -1-1 (kg hayear of bioelements returning ) to the...
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Báo cáo y học: " HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic interventio" ppsx
... and are therefore not subject to the cell-cycle arrest function of Vpr and even lack the prerequisite ATR induction in the presence of Vpr [132] The findings that demonstrate the importance of ... combination with the aforementioned abilities of Vpr to increase viral replication by inducing G arrest and activating the HIV-1 LTR, the potential of Vpr to promote infection of and survival of macrophages ... the minor and Page of 20 severe forms of HAND have common etiologic mechanisms, there is reason to suspect the importance of HIV infection in macrophages in the central nervous system (CNS) and/ or...
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Báo cáo khoa học: "Antimicrobial resistance and patient outcomes: the hazards of adjustment" pptx
... confounder An example of this potential pitfall occurs when adjusting for physiological scores measured at the time of the onset of the infection Recording the APACHE score at the onset of infection is ... individually and together, in order to determine as accurately as possible the true independent predictors of the outcome under study 10 11 Zavascki and colleagues, in the first reported outcomes study of ... accounted for the intermediate variable of inappropriate therapy, and thereby provided a plausible explanation for the effect of resistance on mortality via its effect on appropriateness of therapy...
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Báo cáo y học: " The international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and patient outcomes" ppsx
... assess the use of DrotAA, it was one of a number of therapeutic interventions on which data was collected The purpose of the study presented here is to compare baseline characteristics and outcomes ... conception and design of the registry RB, GM, FB, JJ, KG, and DPS contributed to the development and conduct of the principal analyses All authors contributed to drafting and critically revising the ... 2004, and that recruitment in PROGRESS in many countries was largely completed by the end of 2004 Therefore, the SSC guidelines existed for only a small portion of the study duration, and thus the...
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Báo cáo sinh học: "Quantitative estimation of genetic risk for atypical scrapie in French sheep and potential consequences of the current breeding programme for resistance to scrapie on the risk of atypical scrapie" pptx
... test by the French standard COFRAC (NF EN ISO/CEI 17025) PrP polymorphisms at codons 136, 141, 154 and 171 of the 248 AS cases were analysed after direct sequencing of the coding region of the PRP ... on the genotype, the age and the surveillance stream Considering that the animals tested from a given flock had the same distribution of age and surveillance stream as the general population, the ... increased the robustness of our results The maintenance of the polymorphism of the PRNP gene raises question This could be explained by an absence of selection due to the late onset of clinical...
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samuelson - the great inflation and its aftermath; the past and future of american affluence (2008)
... about themselves and their society; h o w they voted and the nature of their politics; h o w businesses operated and treated their workers; and h o w the American economy was con nected with the ... and President Nixon's resignation; the sexual revolution; the invention of the computer chip; R o n a l d Reagan's election in 1980; the end of the Cold War; the creation of the Inter net; the ... in the endless abundance of resources, convictions so deeply rooted in the * The Bureau of the Budget is now the Office of Management and Budget (OMB) 16 The Lost History American character and...
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The NR4A orphan nuclear receptors are target genes of the novel drug c1 in cancer cells and potential mediators of drug induced apoptosis
... Pervaiz, Professor, Department of Physiology, Yong Loo Lin School of Medicine, NUS Their encouragement and guidance and their critique has been of paramount importance in directing the course of the ... Accordingly, the great and urgent need presently is to investigate the role of each of the plenitude of genes and proteins important in the progression of cancer NUCLEAR RECEPTORS The nuclear ... directing the formation of a complex where VDAC and ANT isoforms may be at least 25 partially redundant and become included in the PTPC depending upon their availability or on the nature of the apoptoic...
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The expression of CD44s in squamous cell carcinoma of the oral tongue and association with clinicopathological factors and survival outcomes
... understanding of the intrinsic and extrinsic mechanisms of how these tumourigenic cells resist conventional treatments, self renew and metastasize may allow for the development of novel therapies and ... elucidated, and extrinsic factors of the microenvironment may conceivably contribute.36, 37 A better understanding of the complex interaction of cancer stem cells and chemotherapeutics is therefore ... possible without the guidance and the help of several individuals who in one way or another contributed and extended their valuable assistance in the preparation and completion of this study I...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25