... oxidation and proinflammatory cytokine expression in the lungs Hemorrhage and resuscitation In murine models, for example, mRNA levels of proinflammatory and immunoregulatory cytokines, including IL-1α, ... Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of cateκ cholamines in nuclear factor-κB regulation and cytokine expression J Clin Invest 1997, 99:1516-1524 Moine ... cytokines and other proinflammatory mediators in the lungs Moine et al examined cytoplasmic and nuclear NF-κB counter-regulatory mechanisms in lung mononuclear cells, using a murine model in which...
Ngày tải lên: 12/08/2014, 19:21
... Targeting the NF-κB pathway may therefore be a promising therapy to reduce injury and to improve lung function play a central role in initiating the innate immune system and in activating NF-κB ... NADP, nicotinamide dinucleotide oxidized; NADPH, nicotinamide dinucleotide reduced; PKC, protein kinase C; ROS, reactive oxygen species; SAPK, stress-activated protein kinase DNA binding In hypoxia, ... several genes encoding proteins involved in oxygen and energy homeostasis is controlled by HIF-1 Since EPO gene expression is inhibited by the proinflammatory cytokines, such as IL-1β and TNF-α, while...
Ngày tải lên: 12/08/2014, 19:21
Báo cáo y học: "Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation" docx
... color indicates CK19 positive staining Arrows indicate bile duct staining Arrowheads indicate hepatocytic staining PV, portal vein; BD, bile duct Scale bar = 100 μm injuries towards self renewal ... The primary antibody was then linked to biotinylated secondary antibody followed by routine avidin-biotin complex method Diaminobenzidine was used as the chromogen, which resulted in a brown reaction ... Biliary injury and regeneration following DAPM toxicity (A) Serum bilirubin levels indicative of biliary injury after DAPM (50 mg/ kg) administration in F344 rats over a time course * indicates...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: "Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma" docx
... which included 17 genes with p53 binding sites in cluster A and 26 genes with NF-κB binding sites in cluster B In cluster A genes with p53 binding sites, putative models containing three and four ... transcription factors associated with NF-κB were ETSF (human and murine ETS1 factors; 8/14) and ZBPF (zinc binding protein factors; 8/14) In most cases the locations of NF-κB binding sites were ... NM_003528 h IGFBP2 Insulin-like growth factor binding protein (36 kDa) NM_000597 hmr (hr) LGALS3BP Lectin, galactoside-binding, soluble, binding protein NM_005567 hmr MATN2 Matrilin NM_002380 h (hmr)...
Ngày tải lên: 14/08/2014, 07:21
Báo cáo sinh học: " Plasmid-encoded NP73-102 modulates atrial natriuretic peptide receptor signaling and plays a critical role in inducing tolerogenic dendritic cells" pdf
... receptor-2 (TLR2) and suppressor of cytokine synthesis-3 (SOCS3) are key players in integrating NPRA signaling with innate immunity and in the induction of tolerogenic DCs Materials and methods Isolation, ... used (Figure 1B) Intracellular Inhibiting NPRA signaling in human DCs induces Tregs Since blocking NPRA signaling by transfection of hmDCs with pNP73-102 up-regulates IL-10 and TGF-b expression, ... support the hypothesis that inhibition of NPRA signaling and TLR2 expression in DCs induces more IL-10 and TGF-b secretion and increases Zhang et al Genetic Vaccines and Therapy 2011, 9:3 http://www.gvt-journal.com/content/9/1/3...
Ngày tải lên: 14/08/2014, 19:22
Real time monitoring and control of critical dimensions in lithography
... Chapter Introduction 1.1 Motivation The continuing down-scaling of the transistor printed on the silicon wafer has been driven principally by the demand for the faster and larger scale integrated ... succeeds in predicting the experimental wafer temperatures using the bake-plate temperature and the input signal without resorting to the use of any fitting parameter and is therefore useful for scaling ... with invaluable advice and guidance throughout my time at university concerning my research, writing, organization, and life His insights in the semiconductor process control are always stimulating...
Ngày tải lên: 08/09/2015, 19:26
Aesthetic/Cosmetic Surgery and Ethical Challenges pdf
... of surgery and body image Effects of self-monitoring on cosmetic surgery tend to diminish whenever social acceptance and body image variables are controlled [25] For both plastic surgeons and ... medically based cosmetic procedures and interventions In fact, with cosmetic surgery trending toward less invasive procedures and away from formal surgery in both private and academic settings [3, 28], ... existing providers of cosmetic surgery, including fellow plastic surgeons and members of other specialties offering the same type of cosmetic surgery [42] ‘‘Buyers’’ (patients) have increasing...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: "Body image disturbance and surgical decision making in egyptian post menopausal breast cancer patients" pptx
... Farrar W, Andersen BL: Comparing Surgical Groups and Determining Individual Differences in Postoperative Sexuality and Body Change Stress J Consult Clin Psychol 2000, 68(4):697-709 Kenny P, King LM, ... affective impact of body image distress during pre and postoperative period for both studied groups Assessment Assessment of affective impact of body image distress during pre and postoperative ... Figure Assessment of behavioral impact of body image distress during pre and postoperative period for both studied groups Assessment of behavioral impact of body image distress during pre and postoperative...
Ngày tải lên: 09/08/2014, 04:21
Báo cáo y học: "Body image change and improved eating selfregulation in a weight management intervention in women" pdf
... which include a body image module, can be an effective way of improving body image [25,57] The present results extend previous findings by distinguishing evaluative and investment body image ... control and to analyze the distinct effects of evaluative and investment body image components The present findings are informative for professionals when designing future interventions, reinforcing ... least in women Results showed that this study’s intervention led to improvements in both dimensions of body image, increasing body satisfaction, and decreasing dysfunctional investment in appearance...
Ngày tải lên: 14/08/2014, 08:20
The influence of socio cultural factors on body image satisfaction among singaporean college women
... thin body image appearing in various media programs, and their interactions with peers and family members regarding body image have great impact on their understandings of ideal female body image ... unrealistic ultra-thin body image In order to minimize the gap between the internalized thin ideal body image and their own body image, some women are inclined to adopt disordered eating behaviors ... when body image bothers me Like Cindy and Amanda, Mandy is not upset about her weight and body image, even though she aspires to becoming thinner Mandy admits it’s important to have a thin body image, ...
Ngày tải lên: 13/10/2015, 15:54
Báo cáo y học: "Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature"
... MRI of twin A shows a left middle cranial fossa cystic lesion with low and high signal intensities on T1- and T2-weighted images (d), (e) & (f) Brain CT and T 1and T2-weighted MRI of twin B shows ... 12-year-old MZ with mirror-imaging of AC in the cerebellopontine angle and indicated that genetic factors were important in the predisposition to cystogenesis in some patients Previously, both the ... of AC and the presence of AC in patients with genetically determined cystic diseases, such as ADPKD, have indicated a genetic component in the cystogenesis of AC18 The interesting feature in our...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"
... possible effective and fast screening tool Our study also examined the risk factors for OAB in men We found that OAB increased with age: 49% in men aged 40-49 years to 79% in men aged 70-79 years ... Schulz J and Corcos J A population-based study of urinary symptoms and incontinence: the Canadian Urinary Bladder Survey BJU Int 2008; 101:52 Milsom I, Abrams P, Cardozo L, Roberts RG, Throff J and ... stress incontinence in middle-aged women BJOG 2004; 111:600 Coyne K, Margolis M, Zyczynski T, Elinoff V and Roberts RG Validation of an OAB screener in a primary care patient population in the...
Ngày tải lên: 25/10/2012, 11:35
Improvement of Water Quality by Removal of Suspended Solids and High-speed Biological Filtration in Closed Water Body
... experiment was carried out in the field, some disturbances such as typhoon, heavy rain and windy day were met These disturbances had influence on temperature, SS, turbidity and the inflow of water, but ... metal-contaminated soils and groundwater: an evaluation, Engineering Geology, 60(1-4), 193-207 [5] Robert H Kadlec and Robert L Knight Treatment Wetlands CRC Lewis Publishers 1996 [6] APHA, AWWA and ... 423-432 [3] S S Lau and L M Chu The significance of sediment contamination in a coastal wetland, Hong Kong, China, Water Research, 34(2), 2000, 379-386 [4] C N Mulligan, R N Yong and B F Gibbs Remediation...
Ngày tải lên: 05/09/2013, 08:40
Mcgraw Hill 400 Must Have Words For The Toefl - Mind and Body
... essential information of this passage? a b c d Cosmetic surgery is dangerous Many people not have cosmetic surgery because of the pain Cosmetic surgery is increasing in popularity in the United ... murder in the first Bonus Structure— degree Criminal investigators persisted in their questioning Indeed indicates of friends and family, only later finding the motive: money that an idea in an ... have been inflicted by someone administering medicine or poison From there, the poison could travel through the veins, shutting down vital organs and causing death within seconds Indeed, the...
Ngày tải lên: 01/11/2013, 15:20
Practical periodontal plastic surgery
... and Training Ming Fang Su and Yu-Chuan Pan Introduction Training in microsurgery Basic microinstrumentation Suturing techniques An animal model for microsurgery technique training References ... patency and observe any leakage Training may continue on the chicken’s fascial tissue, nerve, vein, and bone During the training for microsurgery, every trainee has to learn the technique for tying, ... Sling suture keep a soft diet and to avoid alcoholic beverages and hot or spicy food for the next 48 h The patient should also refrain from rinsing, physical exercise, and taking drugs containing...
Ngày tải lên: 04/01/2014, 18:00
Tài liệu TRADITIONAL AND NOVEL RISK FACTORS IN ATHEROTHROMBOSIS pptx
... differentiation of EPCs and their homing to sites of vascular injury are complex and involve several mediators and receptors, such as P-selectin glycoprotein ligand-1, CXC chemokine, and integrins (Chavakis ... fibrinolysis factors and promoting platelet function (Kornecki et al., 1988, Moir et al., 2002) Inhibition of interaction between p-selectin and p-selectin glycoprotein ligand reduced fibrin formation ... circulating platelets by inducing a conformational change in the glycoprotein receptors and enabling cross-linking or adhesion via fibrinogen and other adhesive ligands During this process, activated...
Ngày tải lên: 12/02/2014, 16:20
Tài liệu Báo cáo khoa học: Dmrt1 genes at the crossroads: a widespread and central class of sexual development factors in fish pdf
... by a conserved DNA-binding motif known as the Doublesex- and Mab-3-related (DM) domain Being a noncanonical cysteine-rich DNAbinding motif, this domain has two highly intertwined finger structures ... chelate one zinc ion each, and binds to the minor groove of the DNA [6] Dmrts were originally described to play important roles during sex determination in flies and worms by regulating several ... pair in medaka Gonadal dmrt1 gene expression across different fish species An amazing variety of sex-determining systems is found in fish Although information is emerging about sex determination in...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu HEMATOPOIETIC GROWTH FACTORS IN ONCOLOGY BASIC SCIENCE AND CLINICAL THERAPEUTICS pptx
... have delineated the potential beneficial activities of HGF in current clinical use, including studies exploring dosing and scheduling parameters that inform the clinical use of these agents in the ... study of recombinant human interleukin 11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cylclophosphamide and doxorubicin J Clin Oncol 1997; ... resulted in a transient eosinophilia and neutrophilia and granulocyte in ltrates in lymph nodes and duodenal submucosa The transient eosinophilia was unexpected but was also seen in patients receiving...
Ngày tải lên: 16/02/2014, 07:20
Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc
... proline-rich and glutamine-rich N-terminus, which is important for transactivation, is shown in yellow, and contains the PY-motif (green) The helix–span–helix domain at the C-terminus shown in ... AP-2e in chondrogenesis Overview of the differentiation stages during chondrogenesis and the involvement of transcription factors (henatoxylin and eosin-stained section of an embryonic cartilaginous ... transcription factors Essential transcription factors in chondrocyte differentiation are Sox9 and Runx2 Sox9 plays a key role in chondrogenesis, as an inactivating mutation in the gene encoding Sox9...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Roles of heat shock factors in gametogenesis and development pptx
... coronal section and scheme of the coronal section at E14.5 in (F) (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline Surprisingly, the ... before and after birth in mouse brains [122,124] No HSF4 DNA-binding activity was reported in the developing mouse brain so far However, Hsf4b is expressed in the adult mouse brain, including cerebellum, ... seems to be intimately correlated with neurogenesis and neuronal migration in different parts of the mouse brain HSF1 and HSF2 might interact in the developing mouse brain in a stage- and tissue-specific...
Ngày tải lên: 18/02/2014, 04:20
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