correlations between quantitative measures of genome evolution expression and function
Cross-species comparison of genome-wide expression patterns pptx
Ngày tải lên :
09/08/2014, 20:20
... signaling pathways and neuronal functions [9] Cross-species comparison of specific biological processes Besides the global expression modules, comparison of the expression patterns of genes involved ... Figure Combining sequence and expression data to make functional assignments Each of five sets of orthologous genes is represented by a different shading, and each of four organisms is indicated ... significance of expression profiles in two or more species jointly Several studies using microarray expression data have suggested that there has been rapid divergence of expression between duplicated...
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Báo cáo y học: " Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays" pptx
Ngày tải lên :
09/08/2014, 20:21
... environmental response, and reproduction and development Page 10 of 14 Conclusions We have presented a new genome scanning technique that allows the discovery of polymorphic loci and returns quantitative ... greater understanding of the role of environmental variation in shaping genetic diversity patterns and help reveal the genetic basis of adaptive evolution in natural populations Materials and methods ... Echinoidea In Reproduction and Development of Marine Invertebrates of the Northern Pacific Coast: Data and Methods for the Study of Eggs, Embryos, and Larvae Seattle, WA: University of Washington Press;...
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Báo cáo y học: "Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the protein" ppsx
Ngày tải lên :
14/08/2014, 14:21
... characteristics of a protein to its expression profile Subramanian and Kumar [3] have shown a connection between a protein's phyletic age and the intensity of expression, as measured by the number of expressed ... between age and expression is spurious due to the misclassification of rapidly evolving genes and the connection between tissue expression and recent rate of evolution, Subramanian and Kumar [3] ... correlation between age and rate of evolution We wanted to verify that the expression patterns observed here cannot be explained purely in terms of variation in the recent rate of evolution, and so...
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Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc
Ngày tải lên :
19/02/2014, 06:20
... compilation ª 2006 FEBS 3673 Expression and function of Noxo1c R Takeya et al Expression of Noxo1b and Noxo1c in various human tissues The expression patterns of the Noxo1b and Noxo1c messengers were ... compilation ª 2006 FEBS 3665 Expression and function of Noxo1c R Takeya et al Expression of Noxo1b and Noxo1c in various human tissues To compare the distribution pattern of Noxo1b and Noxo1c, we designed ... R Takeya et al Expression and function of Noxo1c A B C D F E G FEBS Journal 273 (2006) 3663–3677 ª 2006 The Authors Journal compilation ª 2006 FEBS 3667 Expression and function of Noxo1c R Takeya...
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Báo cáo khoa học: Sulfation of hydroxychlorobiphenyls Molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases docx
Ngày tải lên :
08/03/2014, 02:20
... Detection of zebrafish SULT1 ST1 and ST2 mRNAs and (B) Western blot analysis of zebrafish SULT1 ST1 protein (A) Detection of zebrafish SULT1 ST1 and ST2 mRNAs in cultured zebrafish cells (lanes and 3) and ... dose-dependence of the regulation of the activity of the zebrafish ST by these divalent metal cations and their modes of action Fig Effects of divalent metal cations on the sulfating activity of the zebrafish ... concentration of the divalent metal cations tested was mM, and the concentration of NaCl tested was 10 mM 2410 T Sugahara et al (Eur J Biochem 270) Expression of sebrafish SULT1 ST1 and SULT1 ST2...
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Comparision between background concentration of arsenic in urban and non urban areas of florida
Ngày tải lên :
15/03/2014, 23:22
... correlation between concentrations of arsenic and concentrations of Al and Fe in surface soils of Poland He concluded that levels of most elements were mainly controlled by the minerals (Fe and Al ... understand the temporal variation of arsenic in different compartments in both urban and non-urban areas so that better decisions can be made about land application of waste and remediation of possibly ... 20% depending on the scale and budget of project) A value of 20% was used and the minimum number of samples needed for Gainesville was determined to be 130 Three land-uses were selected for sampling...
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Báo cáo khoa học: Mapping contacts between regulatory domains of skeletal muscle TnC and TnI by analyses of single-chain chimeras potx
Ngày tải lên :
16/03/2014, 18:20
... the investigation of activity [27], the creation of antibody chimeras [28], and the study of Table The ratios of the volumes (V) of the models built by SAXS and of the structure of TnC(1–91) (1SKT) ... function of the molecule The studies of isolated domains lead to the conclusions that the interaction between TnC and TnI is antiparallel [10], and that the inhibitory region and the region between ... with excitation at 280 nm and a bandpass of nm, and emission at 320 nm with a bandpass of nm All spectra were baseline corrected with the buffer and were the means of at least three independent...
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Báo cáo khoa học: Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates potx
Ngày tải lên :
28/03/2014, 22:20
... 3.4.21.76) and CG [20,21,23] However, to date, no in depth investigation of the S¢ specificity of CG has been carried out that could aid the understanding of its pathophysiological function, and distinguish ... result of the presence of negatively-charged residues at P2 and P2¢ that are not accommodated within the b2-tryptase active site because of the presence of Asp147 and Asp143 within the S2 and the ... S¢ specificity of both CG and chymase is less well documented than S specificity; thus, a better knowledge of the combination between S and S¢ specificities could help to distinguish between the specificities...
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Báo cáo khoa học: Expression and functional characterization of P2Y1 and P2Y12 nucleotide receptors in long-term serum-deprived glioma C6 cells ppt
Ngày tải lên :
30/03/2014, 08:20
... proliferative and differentiation state, basal level of ERK1 ⁄ and Akt kinase phosphorylation, and P2Y1 and P2Y12 receptor protein expression and functional activity Examination of the effects of specific ... characterized by increased expression of the P2Y12 receptor and low expression of the P2Y1 receptor In cells grown in medium containing 10% (v ⁄ v) fetal bovine serum, the expression ratio of the two receptors ... ⁄ G1, 25% in G2 ⁄ M, and 15% in S phase After 24 and 48 h of serum starvation, 80% and 90% of cells were growth arrested, respectively However, there were still a number of unsynchronized cells,...
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the interaction between the frequency of market quotes spread and volatility in forex
Ngày tải lên :
23/04/2014, 15:52
... 378 Kaul and Lipson (1991), Lamoureux and Lastrapes (1990), Bollerslev and Domowitz (1991)] On the other hand, Lamoureux and Lastrapes (1990) and Laux and Ng (1991) find that the use of contemporaneous ... Lamoureux and Lastrapes (1990) and Laux and Ng (1991) support the second The second relationship also supports the model of Brock and Kleidon (1990) where the link between variations in demand and ... Department of Finance, University of Texas at Austin O’Hara, M and Oldfield, G S (1986) The Microeconomics of Market Making, Journal of Financial and Quantitative Analysis, 21, pp 361—76 Oldfield, G and...
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Báo cáo sinh học: " Relationship between the loss of neutralizing antibody binding and fusion activity of the F protein of human respiratory syncytial virus" doc
Ngày tải lên :
18/06/2014, 18:20
... sitedirected mutagenesis of the HRSV F protein AD and RS participated in the design, oversight of the conduct of the experiments, and interpretation of the results All authors have read and approved the ... neutralizing mAb binding, and fusion activity as previously described [21] in an attempt to better understand the mechanism of action of HRSV neutralizing antibodies and the impact of resistance to these ... between subgroup A and B, as well as with bovine RSV Given this high degree of conservation, it was somewhat surprising that the functional analysis of the fusion activity of the panel of mutations...
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báo cáo hóa học: " Induction of serine racemase expression and D-serine release from microglia by amyloid β-peptide" pdf
Ngày tải lên :
19/06/2014, 22:20
... elevation of phagocytic activity, cytokine expression, and production of NO and reactive oxygen species [13-15] Because of the ability of D-serine to cooperate with glutamate in physiological and pathological ... Expression of serine racemase mRNA in activated microglia Expression of serine racemase mRNA in activated microglia Semi -quantitative RT-PCR was performed to detect mRNA for serine racemase and ... 71.1% of control (±8.08), and µM D-serine resulted in a value that was 11.54% of control (±7.50) D-serine also generally potentiated the toxicity of low levels of glutamate (data not shown) Page of...
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Báo cáo hóa học: " Relationship between the loss of neutralizing antibody binding and fusion activity of the F protein of human respiratory syncytial virus" doc
Ngày tải lên :
20/06/2014, 01:20
... sitedirected mutagenesis of the HRSV F protein AD and RS participated in the design, oversight of the conduct of the experiments, and interpretation of the results All authors have read and approved the ... neutralizing mAb binding, and fusion activity as previously described [21] in an attempt to better understand the mechanism of action of HRSV neutralizing antibodies and the impact of resistance to these ... between subgroup A and B, as well as with bovine RSV Given this high degree of conservation, it was somewhat surprising that the functional analysis of the fusion activity of the panel of mutations...
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Báo cáo hóa học: " Inhibition of cytokine gene expression and induction of chemokine genes in non-lymphatic cells infected with SARS coronavirus" doc
Ngày tải lên :
20/06/2014, 01:20
... extracted and treated with DNase I For reverse transcription (RT), µg of RNA was incubated with 200 U of Superscript II reverse transcriptase (Invitrogen) and 100 ng random hexanucleotides in 20 µl of ... also in immunopathogenesis Investigations of the cytokine profiles of SARS patients have shown that the proinflammatory cytokines and chemokines IL-6, IL-8 and IP-10 (CXCL10) are strongly upregulated ... picture of SARS-CoV-induced cytokines In some cases Growth of SARS-CoV in different cell lines Vero cells, which are standard for growth of SARS-CoV [30,31], lack type I IFN genes [32,33] and therefore...
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Báo cáo toán học: "Expression and function of micro RNAs in immune cells during normal or disease state" pptx
Ngày tải lên :
08/08/2014, 17:20
... in development and function of the immune response In addition we will discus their abnormal patterns of expression associated with cancer and why manipulating their levels of expression is such ... cloning of miRNAs, microarray profiling and RT-PCR, was used to identify miRNA expression profile in antigen specific naïve, effectors and memory CD8 T cells The study brought the discovery of dynamic ... the potential targets of miRNAs Elucidating miRNA-target genes and their mechanism of action has given valid clues in understanding the physiological role of miRNAs in vivo, and is paving the platform...
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Báo cáo y học: "Expression and functional properties of antibodies to tissue inhibitors of metalloproteinases (TIMPs) in rheumatoid arthritis" docx
Ngày tải lên :
09/08/2014, 06:23
... activation Several functional properties of TIMPs are of potential importance in the pathogenesis of arthritis Overexpression of TIMP-1 and TIMP-2 is associated with inhibition of apoptosis and invasive ... laboratory, and statistical evaluation of material from RA patients; and preparation of the manuscript LD performed the collection and clinical analysis of patients with degenerative joint diseases and ... revision of the manuscript AT contributed to the conception of the study and study design, statistical evaluation of the results, and preparation of the manuscript All authors read and approved...
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Báo cáo y học: "Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: possible involvement in excessive interferon-γ and anti-double-stranded DNA antibody production" pot
Ngày tải lên :
09/08/2014, 07:20
... staining and flow cytometry for ICOS expression Percentages of ICOS+ cells (panels c and d) and MFIs of ICOS+ cells (panels e and f) are shown CD4+CD45RO+ (panels c and e) and CD8+CD45RO+ (panels d and ... patients and normal control individuals (Figure 2e,f) There was no significant correlation between SLEDAI score and expression of ICOS in these patients with SLE We examined expression of ICOS ... tion of human inducible costimulator ligand expression and function J Immunol 2000, 164:4689-4696 Ling V, Wu PW, Miyashiro JS, Marusic S, Finnerty HF, Collins M: Differential expression of inducible...
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Báo cáo y học: "Expression and function of junctional adhesion molecule-C in human and experimental arthritis" pot
Ngày tải lên :
09/08/2014, 10:20
... (panels and 4) and 15 μm (panels and 3) (c) Quantification of JAM-C expression in OA and RA synovial tissues JAM-C immunohistochemical synovial tissue sections from four different OA and RA patients ... scanned, and the surface of immunoreactive areas was determined and expressed as the percentage of the surface of the image examined Results are expressed as the mean ± standard error of the mean ... cells of lymph nodes, and smooth muscle cells [10,23] All these cells have in common an immunoregulatory function, and the role of fibroblastic cells in the establishment and maintenance of micro-environmental...
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Báo cáo y học: "Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid-sensitive and steroid-resistant patients with systemic lupus erythematosus" pps
Ngày tải lên :
09/08/2014, 14:22
... Evaluation of FCM analysis of GR expression by western blot Analysis of GR repression in (left) K562 and (right) U937 with and without 10-6 M Dex of GR expression by western blot by GR-mAb FCM and western ... in the GR expression and binding (mean ± standard error of the mean) For heterogeneity of variance, Kruskal-Wallis H test and Memenyi test were used Age, gender, dosage of prednisolone and years ... relation of GR and inhibition of cytokine secretion, there was a positive relation between the GR binding in two subsets (T lymphocytes and monocytes) and the inhibition rate of Page of 11 (page...
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Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt
Ngày tải lên :
09/08/2014, 14:22
... cellular proliferation and expression of cytokines and activation markers by peripheral blood T cells [36,37], and that CCL2, CCL5 and CXCL12 upregulated the expression of cytokines and chemokines by ... peripheral B cells of both normals and subjects with RA, and CXCL12 enhanced the expression of ICOSL on both normal and RA B cells In contrast, the effect of CCL20, CCL19 and CCL21 was not significant ... CD19, CD27, and CCR5, CCR6, CCR7, CXCR3, CXCR4 or CXCR5, and the expression of the various markers was analyzed by flow cytometry CD19+ B cells were gated, and the frequency of expression of each...
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