... of Hong Kong University Science Centre Department of Chemistry Shatin, New Territories hncwong@cuhk.edu.hk Prof Dr Chi-Huey Wong Professor of Chemistry, Scripps Research Institute President of ... present the first of a number of personal case studies of FBDD – in this case, the application of the fragment-approach to the development of Hsp90 inhibitors, with emphasis on the role of in silico ... we offer free access to the electronic volumes of the series published in the current year If you not have access, you can still view the table of contents of each volume and the abstract of...
... for a complementary and recent discussion of the motives and use of RRs across the world 4 partly reflects the sectoral and targeted nature of many of these other macroprudential instruments ... composition of banks’ foreign borrowing in a juncture of large capital inflows Third, they can serve as a tool for credit allocation to ease liquidity pressures At times of stress, an asymmetric use of ... requirements in countries where the valuation of assets is highly uncertain—because of a lack of liquid secondary markets, for example—as the true measurement of capital also becomes less certain ...
... was further supported by high profitability of domestic lending, often in the wake of EU accession 17 A combination of instruments has also been used by a number of other European countries that ... particular -7- Box Analysis of the Nature of Credit Growth In determining the risk profile of, and policy response to, rapid credit growth, a more detailed analysis of its characteristics is important ... future risks and returns Risks of contagion and owner’s obligation and ability to control such risks Quality of data (transparency) and of supervision and regulation of markets and institutions...
... indicator of the ability of banks to research and identify profitable ventures, monitor and control managers, ease risk management, and facilitate resource mobilization We not have a direct measure of ... Under the null-hypothesis of the validity of the instruments this test is distributed χ2 with (J-K) degrees of freedom, where J is the number of instruments and K the number of regressors The second ... ratio of government expenditure to GDP as indicators of macroeconomic stability We use the sum of exports and imports as share of GDP and the black market premium to capture the degree of openness...
... spewing his breakfast into the deep blue sea The buoys stayed anchored, offering the surfers a point of reference and a measure of relief When the next set of four or five waves broke, they showed ... top of Bishop Rock, a pinnacle of hard volcanic basalt, in the trough of waves on a very low tide “We went, maybe, four or five times from 1951 to 1958, just commercial fishing for abalone,” Hoffman ... search of surf, but he had never seen anything like this A mile-long mutant Malibu was reeling off in the middle of the ocean Castillo dove low and flew alongside a wave from a height of around...
... IAN ARNOF Chairman Arnof Family Foundation REX D ADAMS Professor of Business Administration The Fuqua School of Business Duke University ALAN BELZER Retired President and Chief Operating Officer ... unavoidable, but the education of the next generation of workers must not suffer THE BENEFITS OF PRESCHOOL America is wasting its education dollars on remediation of past failures Getting it right ... service offered, at least one meal offered and site visits to monitor implementation of quality standards [W Steve Barnett, Jason T Hustedt, Kenneth B Robin, and Karen L Schulman, The State of Preschool:...
... Mean Offer price ~$! Issue size ~millions of $! Offer to open return ~%! Offer to close return ~%! Number of comanagers Size of the syndicate Number of market makers entering quotes in the preopening ... investor who buys at the offer price and sells at the open price Start Time N Mean Size Median Size Mean Return ~%! ~Open Ϫ Offer!0Offer Median Return ~%! ~Open Ϫ Offer!0Offer 9:30–10:00 10:00–10:30 ... manager for four or more offerings during our sample period These 19 banks account for 116 of the 188 offerings in the sample Some of these firms are counted twice because of mergers during the...
... financial needs of foreign owned banks In terms of profitability, the entrance of foreign banks increased the amount of competition in the CEE markets, and hence caused a decline in the profit margins ... growth pattern of their subsidiaries, which constitute the majority of the banking assets in the CEE countries The profitability of the parent bank has an influence on the magnitude of operations ... studies the importance of bank ownership structure for the growth of credit in the CEE countries The foreign bank ownership for the credit growth pattern of the CEE countries is of interest for several...
... of an act of compassion or of an insight into human nature The model also allows for the often mysterious fluctuations in the attribution of creativity over time For example, the reputation of ... of no consequence at all The Oxford Book of English Verse had only one poem of his And now, of course, he was resurrected by Herbert Grierson and T S Eliot and he’s one of the great figures of ... illustration of how the field of art operated in Florence at this time concerns the building of the north and especially the east door of the baptistery, one of the uncontested masterpieces of the...
... for development of planting area, yield, output and marketing 3.2 Results of assessing growth and development of the imported varieties of soybean in Thai Nguyen 3.2.1 Results of assessing growth ... Production, Ministry of Agriculture and Rural Development (2006) [9] showed that: The Northern Midland and Mountainous Region is one of three areas planting high percentage of local varieties of soybean ... fertilizer combination was tons of manure + 40 kg N + 80 kg P2O5 + 40 kg K2O + 300 kg of lime/ha - Trial of soybean planting in winter and spring in three places of Thai Nguyen was successfully...
... reveals conserved TFBSs in each sequence Sequence motifs of the same shape (colored in green) represent binding-sites of the same class of transcription factors TFBS1 and TFBS4 are conserved in ... the extent of required conservation (cut-off), and the length of sequence to search (window size) It is becoming evident that comparative genome analysis is very powerful and will be of use not ... genome and use Journal of Biology 2003, 2:11 11.4 Journal of Biology 2003, Volume 2, Issue 2, Article 11 Zhang and Gerstein them as a blueprint for understanding the mysteries of gene regulation...
... state of photosynthetic apparatus in comparison with control generative plants of the spruce mountain population (Fig 7) The evaluation of water content in shoots after 15 and 180 minutes of controlled ... analysis of variance for morphological traits and the values of chlorophyll fluorescence of trees growing on Černohorská rašelina RP indicates high statistical significance of the influence of provenance ... progeny of clone No 548 again A comparison of the growth of rooted cuttings (2nd generation clones) and control planting stock produced by a routine method shows the relatively good growth of generatively...
... the effects of this type of substrates on the mycorrhizal status of forest seedlings produced in nursery are poorly documented The objective of this work was to evaluate the effects of inoculation ... formation of mycorrhizas The relatively high pH value (7.7) of the substrate could have reduced the efficacy of all fungi tested Since most of them are acidophilous, both the germination of fungal ... response to pH in vitro, Mycologia 75 (1983) 234–241 [37] Williams S., Official methods of analysis of the Association of Official Analytic Chemists, Sidney W (Ed.), AOAC, Inc Arlington VA, 1984...
... force of electron transport to the reduction of the redox state of the primary electron acceptor of PS II, which is approximated by 1–qP Figure also illustrates an estimate of the flux of electrons ... in response to light acclimation There is a lack of fundamental knowledge of the physiological processes controlling early growth and development of oaks compared to other commercially important ... compensation point of Quercus petraea from 6% to 15% Similarly, Wang et al [51] suggested a minimum of 15% of full sunlight was needed to facilitate the early establishment of white oak Quercus...
... (tenth of a mm) of the main stem at the half length of the stem, length of first order branches (mm), diameter (tenth of a mm) of first order branches at its base were measured At the end of the ... control and the two shade treatments (variable Z2) (table I) Branch dry mass of beech was higher than that of oak (negative value of variable Z1), whereas leaf dry mass of oak exceeded that of ... seedlings of the control at the end of the experiment, the reduction of the light quantity seems to be of primary importance (figure 2a and 3a) However, the reduced R/FR-ratio under the green nets...
... availability of water was more limiting to growth than a lack of nitrogen A similar lack of response to a -1 nursery fertiliser application of 80 kg N Leaf water potential of irrigated trees was often ... length of both type of cherry was increased in the presence of irrigation (data not presented) Other workhave also shown that the root length of ers Prunus is increased in the presence of irri- ... each of the degrees of freedom of the variety x nitrogen interaction and of the irrigation x nitrogen and variety x irrigation x nitrogen interactions was confounded in or of the replicates In...
... addition of the ionic mix- ture The effect of acidic rain on the Gn of clone 1019 seemed to depend upon envi- ronmental and/or ecophysiological conditions (interaction pH x ions x d) A reduction of ... significant interaction of pH x ions The Newman-Keuls test yielded the following: 4.0+ 5,6+ 4.0- 6- The conductance of clone 1019 was + also reduced at pH 4.0 and a significant interaction of pH x ions ... were no differences of the parameter estimates between the treatments (P < 0.05) Typical values were: A 142-160 mm, b 5.7-6.9, k 0.13-0.15 d-! The point of inflexion, where half of the final length...
... Management Division of Alberta Environment, RRTAC pp 32-45 status of Lavender D.P (1988) Characterization and manipulation of the physiological quality of planting stock Proceedings of the Tenth North ... constant air temperature of 20°C and soil temperatures of 3, 10 and 17°C Seedling caliper and shoot length were measured prior to and after the treatment period The number of actively growing roots ... zone temperature accounted for significantly more of the variation in root data than did mycorrhizal class The two exceptions were the number of short roots: ) per unit root dry weight and 2)...
... percentage of known actives in the hit list (recall); Ht, the number of hits retrieved; D, the number of compounds in the Page of 13 database; E, the enrichment of the concentration of actives ... the Graduate Institute of Biotechnology of National Taipei University of Technology under HLL’s instruction HLL is a distinguished professor in the Graduate Institute of Table The highest pose ... quality of the pharmacophore models generated; while the test set compounds serve to evaluate the predictive ability of the resultant pharmacophore Both sets of molecules must have large range of...
... transformed cells of cell growth on a methylcellulose solid surface in the form of cell colonies However, growth was transient and the amount of cells quite limited, precluding many types of biochemical, ... systems of Sachs and Metcalf These methylcellulose colonies of leukocytes provided too few cells and growth of these cells were limited in number and in time When we had our next hint of an RT ... was a distinct form of leukemia He named it adult T cell leukemia (ATL) [35] Two events significantly catalyzed the further development of our work and of our understanding of HTLV-1 and its role...