concentration what degree of hyponatremia is acceptable to continue with a planned elective proce
Báo cáo khoa học: A region within the C-terminal domain of Ure2p is shown to interact with the molecular chaperone Ssa1p by the use of cross-linkers and mass spectrometry doc
Ngày tải lên :
15/03/2014, 00:20
... An alternative explanation that can account for this observation is that Ssa1p binds with higher affinity a conformational state of Ure2p as a result of the presence of the N-terminal domain of ... formic acid and stored at )20 °C until MS analysis High mass MALDI-TOF MS High-mass MALDI-TOF mass spectra of the intact protein complexes were obtained using a MALDI-TOF mass spectrometer (Voyager ... steel MALDI target (Opti-TOF; Applied Biosystems) MALDI-TOF-TOF MS and MS ⁄ MS spectra were acquired with a MALDI-TOF ⁄ TOFÔ 4800 mass spectrometer (Applied Biosystems) in the positive and reflector...
- 12
- 510
- 0
Báo cáo Y học: Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts A role for phosphoinositide 3-kinase pot
Ngày tải lên :
24/03/2014, 03:21
... instead acts as a cofactor for the cleavage and activation of PAR4 [27] Thrombin has been shown to cleave and activate PAR1, PAR3 and PAR4, whereas trypsin cleaves and activates PAR2 As duodenase ... Vector Laboratories), followed by treatment with avidin–horse radish peroxidase (Vectastain ABC kit, Vector Laboratories) and diaminobenzidine (DAB kit, Vector Laboratories) Following immunostaining, ... inhibitor) and GF109203X (protein kinase C inhibitor) indicating that each of these pathways has a modulatory rather than a mandatory role to play in mediating the proliferative response In contrast,...
- 10
- 437
- 0
báo cáo hóa học:" Health-related quality of life is related to COPD disease severity" doc
Ngày tải lên :
20/06/2014, 15:20
... analysis Statistical analysis was performed using an analysis of covariance model with HRQL scores as dependent variable Three different approaches to analysis were performed using different classification ... measuring impaired health and perceived HRQL in airways disease It contains 50 items, divided into three domains: Symptoms, Activity and Impacts A score is calculated for each domain and a total score, ... background The association between HRQL and forced vital capacity as a percentage of predicted normal values (FVC % predicted) was also evaluated Methods Study sample A total of 202 subjects with...
- 8
- 412
- 0
Báo cáo y học: "Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility" pptx
Ngày tải lên :
12/08/2014, 20:20
... penalties are compounded by a lack of standards for integrating statistical and judgemental criteria for early stopping The lack of such standards increases the likelihood that stopping decisions ... size is 480 patients, a saving of 320 patients over the 800 patient sample size that we would have without futility stopping The greatest disadvantage of a futility-stopping rule is that it is ... survival and other important outcomes, estimating complication rates, and identifying predictors of response The over-riding goal is to advance clinical care With this assurance, study patients assume...
- 3
- 432
- 0
Báo cáo y học: "Early down-regulation of the pro-inflammatory potential of monocytes is correlated to organ dysfunction in patients after severe multiple injury: a cohort study" pptx
Ngày tải lên :
13/08/2014, 16:21
... response is initiated to dampen the inflammatory process [3-5] Any imbalance of the tightly regulated homeostasis of pro- and anti-inflammatory forces causes either a hyperinflammatory or an immunosuppressive ... protein plasma levels after trauma reveals associations with the clinical course Acta Anaesthesiol Scand 2001, 45:364-370 Gando S, Nakanishi Y, Tedo I: Cytokines and plasminogen activator inhibitor-1 ... synthesis capacity was performed using the calculation of Spearman rank order, as the patients were not normally distributed The level of significance was set at P < 0.001 Statistical analysis was...
- 11
- 301
- 0
Structural and semantic features of english idioms referring to head and a contrastive analysis with vietnamese idioms
Ngày tải lên :
20/12/2013, 18:33
... Similarly, when we say “do not beat a dead horse” we not refer to a carcass of a certain kind of animal but what we mean is that a person should not waste time thinking of an issue that has already ... word meanings This way of naming is based on another way of naming available in a language with a relationship between the two ways Some linguists call this the indirect way of naming For instance, ... often have sandwiches, salads and meat or fish On Sundays, many families have a traditional meat at home: grilled meat with potatoes, vegetables and gravy For many English people, dinner is a main...
- 54
- 1.8K
- 13
Báo cáo toán học: " Overview of principles and implementations to deal with spatial issues in monitoring environmental effects of genetically modified organisms" pot
Ngày tải lên :
20/06/2014, 20:20
... that handles documentation and exchange of metadata (site descriptions, quality control data), measuring data and geodata An appropriate tool to achieve these goals is the implementation of a web-based ... Geostatistics is a point-pattern analysis that generates surface predictions from data points This relies on investigating and modelling the spatial autocorrelation among sample data by variogram ... main meta-database or several interrelated databases Meta-databases should help evaluate on to what extent the data records can be compared with one another for assessment Based on the basic considerations...
- 17
- 558
- 0
báo cáo hóa học:" Overview of principles and implementations to deal with spatial issues in monitoring environmental effects of genetically modified organisms" pot
Ngày tải lên :
21/06/2014, 17:20
... that handles documentation and exchange of metadata (site descriptions, quality control data), measuring data and geodata An appropriate tool to achieve these goals is the implementation of a web-based ... Geostatistics is a point-pattern analysis that generates surface predictions from data points This relies on investigating and modelling the spatial autocorrelation among sample data by variogram ... main meta-database or several interrelated databases Meta-databases should help evaluate on to what extent the data records can be compared with one another for assessment Based on the basic considerations...
- 17
- 390
- 0
Báo cáo y học: "Reproducibility and sensitivity to change of various methods to measure joint space width in osteoarthritis of the hip: a double reading of three different radiographic views taken with a three-year interval" pot
Ngày tải lên :
09/08/2014, 07:20
... statistical section of the protocol, checked the data and performed the statistical analysis IK performed the follow-up of the trial and the radiographic study, and data management BM, TS and ... codes were assigned to radiographs for each reading in order to avoid any identification of a set of radiographs that had already been read (reading one: list numbers 1–50; reading two: list numbers ... Bland and Altman graphical approach Its value is obtained by SDs of the mean of differences between the two measurements As may be calculated from data shown in Tables and 6, the SDD for reader...
- 11
- 410
- 0
Báo cáo y học: ":Evaluation of the Patient Acceptable Symptom State in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis" pptx
Ngày tải lên :
09/08/2014, 10:20
... patient satisfaction by means of the PASS criteria can be approached in a number of ways: satisfaction at the end of a study period, time taken to achieve patient satisfaction, or time taken to ... variables – OA pain, patient's global assessment of disease activity, and WOMAC™ LK 3.1 Function – was originally estimated using the least square means obtained from an analysis of covariance with ... of PASS The statistical analysis of continuous variables is usually considered as more powerful than the analysis of dichotomous variables The concept of PASS does necessitate a switch from a...
- 11
- 455
- 0
Báo cáo y học: "CLOCK is suggested to associate with comorbid alcohol use and depressive disorders" ppt
Ngày tải lên :
10/08/2014, 09:20
... sleep disorders are associated with an abnormal circadian rhythm and display symptoms like disturbed Page of sleep-wake cycle and appetite, as well as abnormal physical functions including changes ... rats have an decreased circadian expression pattern in SCN and various other brain areas after alcohol intake [17] Spanagel and colleagues found that a haplotype in the PER2 gene associated with ... group to show associations with depression in a Swedish population-based and case-control material [11,53] Moreover, NPAS2 is indicated to associate with SAD [54,55] and NPAS2 and ARNTL or ARNTL2...
- 9
- 419
- 0
báo cáo khoa học: " ’To take care of the patients’: Qualitative analysis of Veterans Health Administration personnel experiences with a clinical informatics system" ppsx
Ngày tải lên :
10/08/2014, 10:23
... conducted data analysis and helped to draft the manuscript LP participated in study design, data collection and analysis, and helped to draft the manuscript EY participated in study design and data collection, ... implementation and the value added to the organization by the EHR Participants’ recommendations may help healthcare administrators anticipate barriers to EHR implementation and work to address ... end-users want with what administrators need; this process may also facilitate EHR adoption The results of this study and future studies may provide information that can be used to encourage EHR adoption...
- 8
- 249
- 0
báo cáo khoa học: "Complete clinical response of metastatic hepatocellular carcinoma to sorafenib in a patient with hemochromatosis: A case report" ppsx
Ngày tải lên :
10/08/2014, 22:20
... sorafenib in a variety of tumor types such as renal cell carcinoma, melanoma, thyroid cancer, ovarian cancer, sarcoma, and pancreatic cancer None of these tumor types is characterized by elevated ... evidencebased management of hepatocellular carcinoma – an updated analysis of randomized controlled trials Alimen Pharmacol Ther 2006, 23:1535-47 Llovet JM, Ricci S, Mazzaferro V, Hilgard P, gane ... elevated alpha-fetoprotein or imaging characteristics observed in our patient The case illustrates a patient who had a rapid and complete response to sorafenib therapy, based on imaging and tumor marker...
- 3
- 206
- 0
Báo cáo y học: "Recurrence of suicidal ideation due to treatment with antidepressants in anxiety disorder: a case report" docx
Ngày tải lên :
11/08/2014, 10:23
... Journal of Medical Case Reports 2007, 1:166 regimen, panic attacks continued and his overall state deteriorated eventually leading to hospitalization to a youth inpatient ward Treatment was changed ... treatment of children 2003 Akiskal HS, Benazzi F: Does the FDA proposed list of possible correlates of suicidality associated with antidepressants apply to an adult private practice population? ... understood phenomenon Patients often describe feelings of hopelessness and despair that may develop after starting treatment with an antidepressant [12] that may lead to suicidality The classical action...
- 4
- 280
- 0
Báo cáo y học: "The value of correlation of serum 20S proteasome concentration and percentage of lymphocytic apoptosis in critically ill patients: a prospective observational study" pps
Ngày tải lên :
14/08/2014, 07:21
... Value of SOFA (Sequential Organ Failure Assessment) score and total maximum SOFA score in 812 patients with acute cardiovascular disorders Crit Care 2001, 5:P225 O’Brien MC, Bolton WE: Comparison ... proteasome as a part of proteasome complex is elevated in critically ill patients, whether septic or non-septic, and this elevation is partially due to enhanced and increased cellular damage and ... preparation of this manuscript Author details Department of Anesthesia, Tanta University Hospitals, El-Geish Street, Tanta 31527, Egypt 2Department of Clinical Pathology, Tanta University Hospitals,...
- 13
- 265
- 0
Báo cáo y học: "Mean glucose during ICU admission is related to mortality by a U-shaped curve in surgical and medical patients: a retrospective cohort study" docx
Ngày tải lên :
14/08/2014, 07:21
... from cohorts of patients with a medical and a surgical admission diagnosis from a general ICU of a teaching hospital in The Netherlands Materials and methods Cohorts, setting, and data collection ... of disease is the use of the APACHE II score, because the use of APACHE II score to predict mortality is not validated for cardiac surgery patients However, this adjustment is the best available ... interval our and other ICU cohorts is the high percentage of patients admitted after cardiac arrest (Table 2), a population with a high mortality rate Also, the percentage of patients with diabetes...
- 9
- 305
- 0
