computational prediction of viral mirnas

... genomes Table 2: Comparison of the number of viral microRNAs predicted by the ab-initio prediction algorithms-BayesmiRNAfind, mir-abela, mirSVM and our method on a dataset of viral microRNA precursors ... 22 out of the 23, 11 out of 13 and 10/11 of the microRNAs expressed by EBV, KSHV and CMV respectively The comparisons of different programs are summarized in Table Average Frequencies of sequence-structure ... elements can be used for efficient ab-initio prediction of microRNA hairpins Recently a number of ab-initio prediction methods for microRNAs Page of (page number not for citation purposes) Virology...

Ngày tải lên: 12/08/2014, 04:20

... assessment of the quality of PathoLogic's predictions and to check for pathways not previously thought to occur in humans We also compared the metabolic network of HumanCyc to that of two of our ... polymerases) Our best estimate of the total number of human metabolic enzymes is the sum of the 1,653 known enzymes plus the 203 pathway holes, for a total of approximately 6.5% of the human genome allocated ... our understanding of the human metabolic network The query and visualization capabilities of the Pathway Tools software (such as the visual- The user of HumanCyc should be aware of several potential...

Ngày tải lên: 14/08/2014, 14:21

... frequency of occurrence of particular wind conditions in May 198 Figure App.1.5 The frequency of occurrence of particular wind conditions in Jun 198 Figure App.1.6 The frequency of occurrence of ... frequency of occurrence of particular wind conditions in Aug 199 Figure App.1.8 The frequency of occurrence of particular wind conditions in Sep 199 Figure App.1.9 The frequency of occurrence of ... capacity of wall refers to the amount of heat required to elevate the temperature of a unit volume of the wall, or unit area of the surface, by one degree They are namely volumetric heat capacity of...

Ngày tải lên: 14/09/2015, 13:58

... sequence features The aim of this study was to integrate DNA sequence features for more accurate prediction of replication origins in some double-stranded DNA viral genomes A computational method ... Summary of window scores of repeats in herpesviruses (log(R + 1)) 42 3.4 Summary of window scores of AT content in percentages in herpesviruses 42 3.5 Summary of window ... features to improve the prediction of likely locations of replication origins in herpesviruses Sections 1.1 and 1.2 provide an overview of the motivation and background of our study In Section...

Ngày tải lên: 16/09/2015, 12:17

... different species can be used to predict the origin of sequences Focus is on the viral sequences Implement software tools for the purpose of prediction of viral and allergen sequences CHAPTER INTRODUCTION ... because the prediction method 38 CHAPTER VIRAL SEQUENCE PREDICTION has to be able to classify unknown sequences independent of the knowledge of its reading frame 39 CHAPTER VIRAL SEQUENCE PREDICTION ... specificity of AllerHunter to match that of APPEL, the number of false positives generated will push estimate of allergens in Swiss-Prot to around 3.0%, a closer match to the prediction of 2.9% by...

Ngày tải lên: 30/09/2015, 13:49

... they be offered? 69 6.4.1 Who will be developing agents, and how will they be offered? 69 6.4.2 What kinds of agents will be offered? 71 6.4.2 What kinds of agents will be offered? ... to get a clear picture of the size of the Internet, let alone to make an estimation of the amount of information that is available on or through it; • The dynamic nature of the information on ... types of agents as well 1.3 Two statements This thesis consists of two parts For each of these two parts a separate statement will be formulated The first part of the thesis is an inventory of agent...

Ngày tải lên: 08/10/2012, 15:22

... (concordant prediction and outcome) and (discordant prediction and outcome); a prediction of 50% has a score of 0.25 both when the outcome is or [42] The development and assessment of prognostic ... without imputation of missing data are 1.61 (1.13 to 2.31; P = 0.01) for the prediction of serious complications and 1.65 (0.97 to 2.79; P = 0.06) for the prediction of death ness of fit test) The ... also no indication of serious miscalibration of these models: A total of 36 serious complications were observed in nonCAP patients compared to predicted numbers of complications of 41.2 and 40.2...

Ngày tải lên: 25/10/2012, 10:02

... to improve the predictions of agricultural losses to runoff and seepage Previous research has shown that the use of RZWQM for simulating the pesticide and movement in the soil profile produces ... communication) The model requires the albedo of dry soil, albedo of wet soil, albedo of crop at maturity, and albedo of fresh residue Albedo is the refraction of incoming solar radiation reflected by ... the rest of the model that there is a crop growing Simulation of atrazine transport The focus of this simulation was on the movement of atrazine after entering the RBS RBS receive runoff from...

Ngày tải lên: 05/09/2013, 09:08

... inner diameter of 50 mm, outer diameter of 60 mm, and a height of 20 mm (Fig 2) This structure exposes 18 mm of the point of the current supply electrode and 12 mm of the point of the voltage ... conductivity of the soil in the center of the column The inner and outer diameters of the stainless steel rods were mm and 16 mm, respectively, and the ratio (I/V2) of the current of an outer ... height of 20 mm at a bulk density of 1.53 g/cm3 The acrylic rings were filled up to a height of 20 cm Degassed water was poured onto the top of the column at a rate of 1.0×10-3 to 2.0× 10-3 cm3/s...

Ngày tải lên: 05/09/2013, 09:38

... realistic representation of the local activation overpotentials, which leads to improved prediction of the local current density distribution This leads to high accuracy prediction of temperature distribution ... changes of temperature and relative humidity 2.1 Computational domain A computational model of an entire cell would require very large computing resources and excessively long simulation times The computational ... durability of fuel cell stack components remains, in most cases, insufficiently understood Lengthy required testing times, lack of understanding of most degradation mechanisms, and the difficulty of...

Ngày tải lên: 05/09/2013, 14:58

Ngày tải lên: 17/10/2013, 11:15

... they be offered? 69 6.4.1 Who will be developing agents, and how will they be offered? 69 6.4.2 What kinds of agents will be offered? 71 6.4.2 What kinds of agents will be offered? ... to get a clear picture of the size of the Internet, let alone to make an estimation of the amount of information that is available on or through it; • The dynamic nature of the information on ... types of agents as well 1.3 Two statements This thesis consists of two parts For each of these two parts a separate statement will be formulated The first part of the thesis is an inventory of agent...

Ngày tải lên: 26/10/2013, 17:15

... University of Colorado at Boulder, Boulder, Colorado, and the University of Waterloo, Ontario Prior to moving to Vienna, he held the positions of Professor and Director of the Institute of Structural ... value of 20 kN and a COV of 0.4, the stiffnesses are normally distributed with a mean value of 10 MNm2 and a COV of 0.2 All variables are pairwise independent 10 Computational analysis of randomness ... www.lehigh.edu/∼dmf206/ Foreword Computational Analysis of Randomness in Structural Mechanics aims at detailing the computational aspects of stochastic analysis within the field of structural mechanics...

Ngày tải lên: 12/01/2014, 22:04

... Lake The ecosystem of West Lake is rather diverse with 232 species of plant, 141 species of phytoplankton, 43 species of zooplankton, 11 species of benthos and about 33 species of fish According ... to the condition of rainy season) or 786kg of Phosphorous (under condition of dry season) per year, it will be eutrophic 3.2.2 Estimating loads of Phosphorous a Estimating loads of Phosphorous ... model of phytoplankton with a variety of major components of lake ecosystems: dB p / dt = ( Pnet , p − G p, z − U p − M p ) B p , where Bp: biomass of phytoplankton; Pnet,p: growth rate of phytoplankton;...

Ngày tải lên: 13/02/2014, 12:20

... levels of apoptotic markers during the late stages of MPyV infection However, comparison of the levels of apoptotic markers and cytotoxicity during the replication of wt MPyV, and replication of ... Recently, viroporins of RNA viruses (such as 6K protein of Sindbis virus, E protein of mouse hepatitis virus, M2 protein from influenza A, 2B and 3A proteins of poliovirus, or p7 and NS4A of hepatitis ... & Beard [30] For analysis of kinetics of apopto¨ sis, 3T6 cells (70% confluence) were infected the virus at a multiplicity of infection of plaque-forming unit per cell Viral adsorption was carried...

Ngày tải lên: 16/02/2014, 09:20

... advantage of p53 mutation analysis, and a unique feature of this database, is the availability of the residual activity of the majority of p53 missense mutants The biological activity of mutant ... mutations are classified correctly in 85% of cases and Table Effect of cut-off value on the prediction accuracy The prediction accuracy, specificity, sensitivity, number of mutants classified and MCC values ... approach Prediction of p53 mutant severity to p53 to arrive at an automated method for the prediction of mutant severity In this paper, we show that this is possible and that we can achieve a prediction...

Ngày tải lên: 18/02/2014, 11:20

... the distribution of superlatives across different text genres Elements of a Computational Treatment of Superlatives For an interpretation of comparisons, two things are generally of interest: What ... 87% of S1 judgements are 'vital', while only 38% of S3 judgements are S1 S2 S3 number of instances 46 15 % of “vital” judgements 87% 59% 38% % of “okay” judgements 13% 40% 60% Table Ratings of ... target of the comparison appears in the same sentence and spans from word to word 14 (the Ancient Society of College Youths) Furthermore, no analysis of the semantic roles of the constituents of...

Ngày tải lên: 20/02/2014, 12:20

... construal of its content" Langacker identifies six important dimensions of imagery; in our semantic analysis of spatial expressions we are interested in just three of these: ZThe issue of which side of ... constraint on the position of the LO relative to a particular side of the RO In the case of the intrinsic interpretation (see section ) of a predication such as "the stool is in front of the desk", the ... scope of predication perspective The remainder of this section is a characterization of each of these dimensions and the consequences that their consideration has with respect to the design of a...

Ngày tải lên: 20/02/2014, 21:20

... number of correct predictions/number of total predictions C, correlation coefficient P(x), number of correct predictions in class x/number total predictions in class Q(x), number of correct predictions ... probability of correct predictions [P(x) in Table 1] P(x) gives the accuracy of the prediction of the x class with respect to the overall amount of total predictions made for that class The prediction ... a function of the reliability index (R) of the prediction The fraction of the total predictions (h) is also shown at increasing R values Q2 (j) is evaluated as the number of correct predictions...

Ngày tải lên: 21/02/2014, 15:20

... The originality of this study is also seen in the collaborative work between both computational prediction and experimental validation In this study, the biological validity of the prediction was ... substrates and intermediates of the pathway are structurally simple, and so the reactions can be easily examined biochemically Thus, the computational prediction of missing enzymes can be verified ... of a pyridoxal 5¢-phosphate-dependent enzyme (data not shown) Enzymatic activity of predicted genes The activity of PA0265 and PA0266 was examined in a coupled reaction, in which conversion of...

Ngày tải lên: 07/03/2014, 09:20