comparative analysis and evolutionary classification of protein structures

... 40 50 60 70 Protein number 80 90 100 110 Figure conformers Modular3flexibility for each protein of the dataset of proteins with Modular flexibility for each protein of the dataset of proteins with ... interactions often mediate the shortest pathways between most residues in the protein Structural properties of modules Modularity of protein function We carried out the modular decomposition of protein structures ... 50 60 Protein number 70 80 90 100 Figure of long-range interactions for each protein of the multi-domain protein dataset Percentage Percentage of long-range interactions for each protein of the...

Ngày tải lên: 14/08/2014, 07:21

... Hierarchical Hierarchical classification and the numbers of domains and domain combinations found in each species Hierarchical classification of eukaryote groups and results for assignment of Pfam domains ... VI and VII ancestors of animals and of deuterostomes (Tables and 2) In animals, protein tyrosine phosphorylation mediated by protein tyrosine kinase plays a crucial role in the processing of ... structural classification of proteins database for the investigation of sequences and structures J Mol Biol 1995, 247:536-540 Riley M, Labedan B: Protein evolution viewed through Escherichia coli protein...

Ngày tải lên: 14/08/2014, 07:21

... lowly expressed protein p is tagged and expressed as a bait and pulls-down proteins p1, ,pk as prey, then the reverse tagging of each protein of p1, ,pk will have a smaller probability of finding ... uni-directionally tested and found reports Figure Proportions of proteins sampled across datasets Proportions of proteins sampled across datasets This bar chart shows the proportion of proteins sampled ... edges, and under the assumption of randomness we expect the number of unreciprocated in-edges and out-edges to be similar More precisely, under the assumption that the direction of the edge is random,...

Ngày tải lên: 14/08/2014, 08:20

... Frequency Profiler, and divide the words of texts into first and second thousand levels, academic words, and the remainder or 'offlist.' Vocabprofilers is used for many research and teaching ... functions, and the structures of language can be explained in terms of these functions: ideational, interpersonal and textual The ideational function expresses our experience of the real world and of ... characteristics and serves its own functions; and the task of linguists and interested people is to discover and understand these characteristics and functions for broadening human knowledge and exploiting...

Ngày tải lên: 02/03/2015, 14:17

... ACF of {εI (n)} and that of {φI (n)} in Star Wars IV (b) The ACF of {εP (n)} and that of {φP (n)} in The Silence of 1 the Lambs 125 63 The ACF of {A3 (ε)} and ... Troopers and (b) the base layer of the spatially scalable The Silence of the Lambs coded at different Q 118 57 The mean sizes of P and B-frames of each GOP given the size of ... gratitude and respect first go to my advisors Prof Andrew Chan and Prof Dmitri Loguinov This work would never have been done without their support and guidance I would like to thank my co-advisor Prof...

Ngày tải lên: 06/11/2012, 10:45

... principles and actual devices Electronic and Optoelectronic Properties of Semiconductor Structures provides engineering and physics students and practitioners with complete and coherent coverage of key ... manual and set of viewgraphs for use in lectures is available for instructors   received his Ph.D from the University of Chicago and is Professor of Electrical Engineering and Computer ... University of Michigan, Ann Arbor He has held visiting positions at the University of California, Santa Barbara and the University of Tokyo He is the author of over 250 technical papers and of seven...

Ngày tải lên: 24/01/2014, 17:34

... ACF of {εI (n)} and that of {φI (n)} in Star Wars IV (b) The ACF of {εP (n)} and that of {φP (n)} in The Silence of 1 the Lambs 125 63 The ACF of {A3 (ε)} and ... Troopers and (b) the base layer of the spatially scalable The Silence of the Lambs coded at different Q 118 57 The mean sizes of P and B-frames of each GOP given the size of ... gratitude and respect first go to my advisors Prof Andrew Chan and Prof Dmitri Loguinov This work would never have been done without their support and guidance I would like to thank my co-advisor Prof...

Ngày tải lên: 26/02/2014, 07:20

... existing information on the use of, and threats to, the Malaysian coastal and marine resources off the Straits of Malacca and the adjacent waters of the Andaman Sea and the Indian Ocean In the process, ... and sand, caused widespread degradation of areas with mineral deposits leaving behind sandy, barren and unfertile land, unattended water bodies, and silted waterways Landslips, particularly of ... Malaysia destruction of rainforests and water catchments, and the subsequent erosion of soils together with the heavily silted run-offs, pollutes the rivers These and other sources of land-based pollution...

Ngày tải lên: 06/03/2014, 15:21

... atoms: Ct of the C-terminus, Cc of Asp and Cd of Glu, and Og of Tyr Positive unit charges were added at the following atoms: Nt of the N-terminus, Nf of Lys, Cf of Arg, and Nd or Ne of His (depending ... I and II of monomer 1, and helices I¢ and II¢ of monomer 2, are intertwined We call this a top-bottom structure The inset of Fig shows a cylinder model of the lowest total energy structures of ... method of Gilson [19] Finally, mean pKa values and their rmsds were calculated using the 24 NMR structures of our final ensemble of dimer structures of RIIa D/D Dielectric smoothing at the protein solvent...

Ngày tải lên: 08/03/2014, 22:20

... hyperkeratosis and the formation of hyperkeratotic warts and corns on the palms and the soles of the feet are caused by chronic arsenic ingestion Discoloration of the skin of the face, neck, and back ... assessment of risk to human health, identification of potential exposure pathways, the characteristics of the affected community, the short and longterm health effects for each chemical, and analysis of ... days, and carrot-twice every days Based on the frequency of ingestion of lettuce and the relative infrequent consumption of radish, an ingestion frequency of once per week was assumed and considered...

Ngày tải lên: 15/03/2014, 23:10

... 120–300 UÆmg)1 protein and recovery levels of 20– 30% In all cases, the analysis by SDS ⁄ PAGE and native PAGE of purified preparations showed only one protein band of 20–22 kDa (Figs and 2; supplementary ... Rao and Dr J Josse for critical review of the manuscript, and Professor W Loffelhardt (University of Vienna, Austria) for ¨ his assistance in N-terminal protein sequencing and some MALDI-TOF MS ... equivalent to that of the host organism, and that the promoters seem to be regulated by the same factors Analysis of the promoter regions of 3954 Sequence and phylogenetic analysis Knowledge of the N-terminal...

Ngày tải lên: 16/03/2014, 11:20

... 10 Expression analysis of the SsHCE1, SsHCE2 and wSsLCE genes (A) Northern blot analysis of expression of the SsHCE gene during development Arrowheads indicate the positions of 28S and 18S rRNA ... northern blot analysis Next, gene expression was determined by RT-PCR (Fig 10B) After 28 cycles of PCR, sufficient expression of the SsHCE1 and SsHCE2 genes was detected, and the band intensity of SsHCE2 ... sequences of black rockfish hatching enzyme cDNAs indicated high similarity (93% and 97% for HCE1 and HCE2, respectively, and 95% for LCE) to those of H hilgendorfi, and the phylogenetic analysis...

Ngày tải lên: 23/03/2014, 07:20

... purification, the issue of analysis of multiprotein complexes will be discussed in an accompanying minireview [9a] Proteome analysis of subnuclear structures: the functional architecture of a complex organelle ... study of dynamic changes at the subcellular level, e.g upon protein translocation and altered protein protein interactions Major requirements are the simultaneous preparation and analysis of different ... lamina and attached protein scaffold; NPC, nuclear pore complex; CS, cytoskeleton; Mito, mitochondria Note the differences in the distribution of ER/ONM, L/M and NPC proteins identification of the proteins...

Ngày tải lên: 23/03/2014, 20:22

... the analysis of the calculated structures revealed a short distances between NH of Leu7 and the side chain carboxyl group of the Asp6 residue (< 0.28 nm), and NH of Leu7 residue and C¼O of Leu5 ... [38,39] Analysis of hydrogen bonds and dihedral angles (F, C) for the average structures generated from members of cis and trans family of cyclo128 [D -Leu5]OP showed that the residues of the cis and ... angle and distance restraints deduced from 3JNH-Na coupling constant and NOE cross peak, respectively Analysis of the (F, C) angles, and the potential hydrogen bonding in calculated structures of...

Ngày tải lên: 24/03/2014, 04:21

... b-strands H and F To form the tetramer, two dimers associate back to back, mainly through hydrophobic contacts between residues of the loops formed by b-strands A and B and b-strands G and H One of ... and D and E and F and surround the entrance of the b-barrel at the open end of the cavity As a result of evolutionary restraints imposed by the multiple interactions established by both RBP and ... b-strands G to F and is flexible in most TTR structures, and for loop 19–22, which connects b-strands A and B and hosts the mutation The movement of the latter loop is not large (the Ca ˚ atom of...

Ngày tải lên: 30/03/2014, 02:20

... appearance of a peak pair with retention times of 8.3 and 9.5 min, and (b) the presence and (c) the correct proportion of the three major mass transitions of CEdGA,B that were used for MS ⁄ MS detection ... thorough removal of RNA from the samples and the use of negative ionization for Fig Restriction digests of CEdG-modified and unmodified pGL3 Control vector For the introduction of CEdG adducts, ... decreasing the amount of transcripts Analysis of the amount of luciferase mRNA of transfected cells by semiquantitative RT-PCR resulted in an approximately 60% reduction of transcripts Therefore,...

Ngày tải lên: 30/03/2014, 04:20

... concentration LaHtot and pH consists out of two major steps, namely, (i) determination of medium related parameters (i.e., the parameters of Eqs (14) and (15)), and (ii) determination of growth and production ... medium and initial pH After calibration, prediction of the time dependent course of pH (and [LaH]) is always possible when a LaHtot profile only is at hand 4.2 Determination of growth and production ... part of projects OT/99/24 and COF/98/008, the Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT), the Fund for Scientific Research-Flanders (FWO) as part of project...

Ngày tải lên: 05/05/2014, 08:44

... First, Beveridge and Nelson (1981), Nelson and Ploser (1982), and Cambell and Mankiw (1987) assume the stationarity of the rst log difference of the real GDP and emphasize on the usage of ARIMA models ... Examining Committee Professor Thom Thurston Date Executive Of cer Professor Michael Grossman Professor Barry Ma Professor Jeffrey Weiss Supervisory Commettee THE CITY UNIVERSITY OF NEW YORK Abstract ... like to thank Professor Thom Thurston and Professor Michael Grossman for their continuous support Their kindness, care and concern are unmatched Both Professors believed in me and gave me strength...

Ngày tải lên: 03/06/2014, 02:10

... The End of Comparative Philosophy and the Task of Comparative Thinking SUNY series in Chinese Philosophy and Culture Roger T Ames, editor The End of Comparative Philosophy and the Task of Comparative ... contributions of the thought of Heidegger, Derrida, and Daoism to a better understanding of this world, and that means an attitude that is more open to different interpretations of the texts of these ... history of thinking brought about and was brought about by a change of the functioning of language, in a reciprocal way, and the dominant theory has since become our standard way of seeing and experiencing...

Ngày tải lên: 11/06/2014, 12:45

... following error analysis and comparison, this method is not included (13) l∈Z Sensitivity analysis and parameter selection The coefficients of c are obtained through the equation: Kc = q Page of (14) ... increases, the performance of the TEM system deteriorates quickly and is worse than that of the traditional ADC at high nonlinearity Page of time and frequency response of the three bases in reconstruction ... converter survey and analysis IEEE J Sel Areas Commun 17, 539–550 (1999) doi:10.1109/49.761034 AA Lazar, LT Tóth, Perfect recovery and sensitivity analysis of time encoded bandlimited signals...

Ngày tải lên: 21/06/2014, 03:20