communication issues in advanced cancer care

... females Cisplatin Carboplatin Doxorubicin Specific Regimens: VAMP w/COP Low Risk/No Risk: Cytarabine Vincristine Methotrexate Dactinomycin Bleomycin Mercaptopurine Vinblastine Page Risk of infertility ... years away from having children of his or her own, thinking about his or her fertility before starting cancer treatment can help increase the chances of being able to have children in the future Talk ... of taking hormone therapy with their doctor Low levels of ovarian hormones also increase the risk of bone thinning (osteoporosis) Getting enough calcium and vitamin D (in the diet or by taking...

Ngày tải lên: 15/03/2014, 01:20

... participating in the response remain to be determined Serotonin may also play a role in the development of cancer anorexia Increased levels of plasma and brain tryptophan, the precursor of serotonin, ... feeding systems are dysfunctional in anorectic tumor-bearing rats NPY injected intrahypothalamically stimulated feeding less potently in rats bearing methylcholanthrene-induced sarcoma than in ... correlate with the presence in the serum of a proteolysis-inducing factor (PIF) that is capable of inducing protein degradation as well as inhibiting protein synthesis in isolated skeletal muscle.1,35,58,66-68...

Ngày tải lên: 15/02/2014, 04:20

... 42 43 in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic ... cancer patients Many clinical trials have been conducted using active specific immunotherapy (ASI) in CRC, including autologous tumor cell vaccines, define-tumor protein vaccines, monoclonal antibodies ... suspected minimal residual colorectal cancer (suspected minimal residual CRC), and reviewed the objective clinical outcomes of ASI in advanced colorectal cancer (advanced CRC) during the past...

Ngày tải lên: 18/06/2014, 19:20

... 2002 using trained interviewers, usually meeting consenting patients and caregivers, in their own homes, who were interviewed separately Clinical and demographic data of patients and caregivers ... lay caregiver or family member Setting Six regional palliative care services in the south of England (London and Chichester) Inclusion criteria were: advanced cancer and receiving palliative care ... that in advanced cancer, where caregiving is intensive, but over a shorter period than for dementia Further, caregiver burden is a concept that emphasizes the 'negative' components of caregiving,...

Ngày tải lên: 18/06/2014, 22:20

... Tessandori R, Tumino R, Piselli P, Dal Maso L: Cancer incidence in people with AIDS in Italy Int J Cancer 2010 Gingues S, Gill MJ: The impact of highly active antiretroviral therapy on the incidence ... new lesions over one month Chemotherapeutic agents used included bleomycin, vinblastine, vincristine, etoposide, cyclophosamide, adriamyacin and prednisone There were no standard chemotherapeutic ... distribution and treatment Initial KS stage was determined using the AIDS Clinical Trials Group staging system that classifies tumour (T), immune (I) and systemic illness (S) status into good and poor...

Ngày tải lên: 20/06/2014, 08:20

... probably could introduce new insight into clinical practice to assure better clinical outcomes By comparing the gene expression patterns of gefitinib sensitive and gefitinib resistant lung cancer, Balko ... lung cancer Ann Oncol 2007; 18(1): 99-103 Sequist LV, Martins RG, Spigel D, et al First-Line Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer Harboring Somatic EGFR Mutations J Clin ... factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib J Clin Oncol 2005;...

Ngày tải lên: 08/08/2014, 17:20

... ultrasound, while directing planes of surgery during the excision This in turn is helpful in guaranteeing both negative margins and an adequate contour of resection in order to minimize the volume ... node involvement is the single most important prognostic factor for survival in breast cancer patients, and consequently information about it provide both staging information and guidance regarding ... this information has resulted in a rapid increment of Breast Fellowship, recognizing that appropriate training is one of the key factors in improving quality of care Currently, the number of...

Ngày tải lên: 09/08/2014, 03:21

... debulking in patients with advanced epithelial ovarian cancer has been compared with chemotherapy and interval debulking in different studies Equal survival has been reported in patients undergoing ... with advanced epithelial ovarian cancer In America 95% of patients with advanced epithelial ovarian cancer are treated with primary surgery [15] Regarding that residual tumor is more than cm in ... indications have not yet determined A critical point in order to define indications of neoadjuvant chemotherapy for advanced ovarian cancer is determination of uniform selection criteria that can...

Ngày tải lên: 09/08/2014, 03:21

... approach in patients with advanced hypopharyngeal cancer Concerning the radiotherapy technique in the treatment of hypopharyngeal cancer, we recommend the adoption of IMRT in the routine clinical ... routine laboratory studies Patients were staged according to the 2002 criteria of the American Joint Committee on Cancer [26] Written informed consent was obtained from the patients for including ... structures by using IMRT are reasonably expected to enable improvement in locoregional control in advanced hypopharyngeal cancer The improvement of locoregional control in advanced head and neck cancer...

Ngày tải lên: 09/08/2014, 08:23

... positive staining of p53 in a representative case of high-grade (G3) ductal carcinoma Immunostaining shows a clear and wide nuclear staining in an high grade (G3) invasive ductal carcinoma Original ... categories: no staining, or weak staining in fewer than 10% of the tumor cells (0); weak staining in part of the membrane in more than 10% of the tumor cells (1+); complete staining of the membrane ... of cancer and the second leading cause of cancer death in women in the USA [1] and its incidence is increasing in many countries, including Italy [2] thus representing a major health problem To...

Ngày tải lên: 10/08/2014, 10:21

... hemoglobin (Hgb) ≥9.0 g/dL, and platelets ≥100,000/mm ; bilirubin ≤1.5 mg/dL, aspartate aminotransferase ≤40 IU/L; creatinine clearance >55 mL/minute The written informed consent was obtained from ... prime vaccine and a single boost were given fifteen days apart For each dose of vaccine, two aliquots were prepared in separated syringes with saline solution (500 μl/dose) containing × 107 cells ... lung cancer vaccine therapy: a concise review J Clin Oncol 2005, 23:9022-9028 Estimativa 2010 - Incidência de Câncer no Brasil - 2010 - INCA [http:// www.inca.gov.br/estimativa/2010/index.asp?link=tabelaestados.asp&UF=BR]...

Ngày tải lên: 10/08/2014, 10:21

... months [49] Paclitaxel-carboplatin-gemcitabine triplet was investigated in two phase II trials involving patients in the first line in one trial, and in 1st/2nd lines in another trial ORRs and CR ... cell carcinoma and in the second line treatment of GIST (gastrointestinal stromal tumors) after failure of imatinib Sunitinib has been tested in bladder cancer as single agent, in combination ... treatment in first line and second line in different metastatic tumors In bladder TCC, bevacizumab (15 mg/kg on day 1) was evaluated in first line treatment in combination with GC protocol (gemcitabine...

Ngày tải lên: 10/08/2014, 21:23

... commitment to reconfiguring clinical research and the need to improve access to state-of-the-art cancer care in community settings Reconfiguring clinical research In 2002, the National Institutes of Health ... the cancer genome atlas) Within each site, activities are thus organized around four core components: reducing disparities in cancer care; increasing the number of patients enrolled in clinical ... National Cancer Institute's Cancer Information Service (1-800-4- CANCER) 2Number of Cancer Patients Treated: Total number of new cancer cases seen at the hospital and the cancer center combined in...

Ngày tải lên: 11/08/2014, 05:21

... sites in terms of immunogenicity, safety and preliminary efficacy of CimaVax-EGF in advanced NSCLC patients In both clinical trials, patients started vaccination month after finishing first line ... decrease of circulating EGF after vaccinating with higher dose at multiple sites Previously, in mice, an EGF vaccine dose resulting suboptimal when administered at a single site, induced a robust ... for each vaccine in the clinical setting Even though we have preliminary evidences of improved immunogenicity and clinical benefit of the new vaccination approach, the definitive information will...

Ngày tải lên: 11/08/2014, 08:21

... sought international accreditation The Joint Commission International (JCI) Accreditation [18], an international recognized body that certifies quality of care in patient care institutions including ... globalizing health care context and a change goal of achieving improved, international standards of care in a developing country Table 3: Performance indicators at King Hussein Cancer Center before ... physician interactions; training and engagement with staff in the clinical setting; and intra-region interactions War room discussions by the leadership team were conducted in English as well as international...

Ngày tải lên: 11/08/2014, 14:21

... safeguards autonomous choice Competing interests The author declares that they have no competing interests References Tillyard ARJ: Ethics review: ‘Living wills’ and intensive care – an overview of the ... JA, Danis M: Can clinical interventions change care at the end of life? Ann Intern Med 1997, 126:381388 Fagerlin A, Schneider CE: Enough: the failure of the living will Hastings Center Report ... an ongoing discussion intrinsic to the doctor–patient relationship Establishing why rather than whether the patient accepts or rejects treatments gives insight into the individual’s world view...

Ngày tải lên: 13/08/2014, 08:20

... ordering costs increase  If Q > EOQ, total carrying costs increase, but ordering costs decrease 28 - 15 Suppose delivery takes weeks Assuming certainty in delivery and usage, at what inventory ... borrowing  T = total amount of cash needed for transactions during the year  F = fixed per transaction cost of selling securities or obtaining a loan 28 - 25 Costs of cash—Holding costs Holding ... changes in inventory levels  All ordering costs are fixed  These assumptions not hold in the “real world,” so safety stocks are held 28 - Total Inventory Costs (TIC) Total Total TIC = carrying...

Ngày tải lên: 06/04/2015, 19:41