cold shock induces change in the membrane potential

... respiration of the uncoupled mitochondria (2.2 ± 6.8 nmol O2Æ min)1Æmg)1) Finally, we examined whether CsA exposure induces changes in ROS production during state III respiration in the presence ... accumulates in cells as a consequence of P-glycoprotein inhibition, resulting in an apparent increase in DWm We also subsequently tested whether P-glycoprotein pumps are involved in the accumulation ... mitochondrial origin It is also unlikely that the calcineurininhibiting properties of CsA play a role, because neither NIM811 nor PSC833 inhibit calcineurin It is furthermore also unlikely that the P-glycoprotein-inhibiting...

Ngày tải lên: 30/03/2014, 08:20

... from the many different localities within the cave Part synthesizes the information presented in the other two parts into a series of analyses designed to explore the implications of the Porcupine ... concern is the question of whether climatic warming will reduce biodiversity to the extent that a given ecosystem loses its ability to maintain the baseline functions that define it Maintaining these ... from the Pit beginning in 1986 For the most part these were not from the CM Pit excavation per se, but from near the surface in the vicinity of the CM excavation, especially beneath and to the...

Ngày tải lên: 17/02/2014, 20:20

... [21,22] Therefore, the incoming Na+ ion is thought to weaken the rather strong interaction between the arginine and the binding site and to promote its loading onto the binding site, aided by the membrane ... ions arriving from the periplasm from escaping to the cytoplasm In order to gain insight into the interaction of the stator arginine with the binding site, we modeled a stretch of seven amino acids ... on these considerations, interaction of the arginine with the proton-binding site is expected to be weaker than with the Na+ ion-binding site A strong interaction between the binding site and the...

Ngày tải lên: 16/03/2014, 06:20

... Engineering in providing services to the government, the public, and the scientific and engineering communities The Council is administered jointly by both Academies and the Institute of Medicine ... making large strides in improving human health In the fall of 2001, the Institute of Medicine convened a committee to examine the roles of academic health centers (AHCs) in the coming decades in ... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the...

Ngày tải lên: 28/03/2014, 23:20

... đổi tổ chức tổ chức công (Theories about Organizational change in Public Organization)  Các nhân tố đóng góp vào thay đổi thành công (Factors contribute to successful change) LÝ THUYẾT VỀ THAY ... Tầm quan trọng tác nhân thay đổi (single change agent) người có ảnh hưởng lớn đến tư tưởng (idea champion)  Sự cần thiết phải có hỗ trợ liên minh dẫn đường (guiding coalition) F Xây dựng hỗ trợ ... dụng hiệu kênh thông tin liên lạc văn hay miệng hình thức tham gia tích cực nhân viên Yếu tố 1: Đảm bảo tính cấp thiết (Ensure the Need) • Một số nghiên cứu khác chứng minh hiệu việc thuyết phục...

Ngày tải lên: 16/04/2014, 02:30

... in the TSLN Both of these effects would appear to be advantageous towards inducing better tumor immunity and protecting against the spread of tumor cells into the draining TSLN While most of the ... on the use of an Ad5IL-12 vector in experimental cancer therapy including prostate cancer with promising results including the ability to aide in the suppression of lung metastases [40,41] The ... zinc-alpha2-glycoprotein (ZAG) expression in adipose tissue [35] ZAG impacts the mobilization of fat stores and breakdown of body fat supporting another indication for the inclusion of RU486 in therapy Thus, the...

Ngày tải lên: 18/06/2014, 16:20

... warming has been getting some attention in the news Global warming refers to the idea that the world’s average temperature has been increasing over the past 150 years, may be increasing more in the ... Assuming global warming is happening, you think it is… Caused mostly by human activities Caused mostly by natural changes in the environment None of the above because global warming isn’t happening ... 2010 Nov 2008 - Q70 When you think global warming will start to harm people in the United States? They are being harmed now In 10 years In 25 years In 50 years In 100 years Never May 2011 32...

Ngày tải lên: 28/06/2014, 23:20

... Stability Theory (HST), arguing that the international system is more likely to remain stable when a single nation-state is the dominant world power, maintaining a hegemony Regarding the global ... aggressive war-making capacity Nevertheless, the leadership in regulating world order is gradually shifting to the emerging countries The article in the Financial Times entitled The End of US hegemony: ... globalization After the Second World War in 1945, the United States and the U.S.S.R maintained high profiles in world politics However, another overlapping basic framework for maintaining international...

Ngày tải lên: 14/07/2014, 13:28

... for inclusion in multivariate models are also presented in Table adjusted for the statistically significant variables included in the multivariate model The key variables included in the final ... included in the final multivariate model are presented in bold All other non-significant variables are also presented adjusted for the variables included in the final multivariate model confirms the ... network TAHOD involves 15 clinical sites in the Asia and the Pacific region Criteria for site selection were based on the ability to contribute data in an appropriate format within the initial 3-year...

Ngày tải lên: 10/08/2014, 05:20

... covers the main themes of the congress The starting point for the treatment of hip disease depends on how we can preserve the natural hip joint and on steps leading to regeneration of the diseased, ... Osteoarthritic Change in the Hip Joint Preservation or Joint Replacement? M Sofue, N Endo (Eds.) Treatment of Osteoarthritic Change in the Hip Joint Preservation or Joint Replacement? With 198 Figures, Including ... pinning in of 11 hips (54.5%), osteotomy in of hips (44.4%), and in situ pinning in of hips Additional operations using bone grafts were performed for avascular necrosis of the femoral head in...

Ngày tải lên: 11/08/2014, 17:20

... normally the blade is inserted into the axis of the femur vertically normal with the convexity of the anterior margin of the femoral head running into a concavity, which was the anterior border of the ... angle (PTA) joint pain developed in patient in whom there was narrowing of the joint space There was a difference in leg length, ranging from 0.5 to 3.5 cm (mean, 0.7 cm), in 11 of the 22 unilaterally ... hip joint Solid line indicates osteotomy line, which declined 20° varus to the line perpendicular to the femoral neck axis B Lateral view of left hip joint Solid line indicates osteotomy line,...

Ngày tải lên: 11/08/2014, 17:20

... posterior tilting angle Results The chief complaint was hip joint pain in 11 patients, pain from the hip joint to the knee in 3, pain from the hip joint to the thigh in 1, femoral pain in 1, and ... 1, and lower limb pain in The mechanism of injury was sports in patients, falling during running in 1, falling on the stairs in 1, long-distance walking in 1, and unknown in 3: most patients ... with the convexity of the anterior margin of the femoral head In Situ Pinning for SCFE 63 In type B, the anterior outline of the head and neck appears as a straight line and the anterior margin...

Ngày tải lên: 11/08/2014, 17:20

... According to the preoperative planning, ARO with 20° varus position was expected to result in more than 34% of the ratio of the intact articular in both the joints The osteotomy was carried out in ... carried out in the right hip joint, and then in the left hip months after the first operation Four years after operations, collapse has not progressed in either of the hip joints, and no OA changes are ... Hatched area indicates necrotic area All the photographs show the anterior view According to anterior rotation, the osteotomy line is 10° inclination away from the perpendicular to the neck (a)...

Ngày tải lên: 11/08/2014, 17:20

... 14c) The tissue, therefore, most likely has originated in the bone marrow If S-100 protein is used to stain the tissue, most cells stain positive, substantiating the finding that they are indeed ... great challenge In the 1860s, improvement of function was attempted with the use of an interposing membrane as a means of preserving the joint For instance, the JK -membrane used by Dr Jinnaka was ... joint gap harbors interposing reparative tissues That is the biological reparative process, triggered in response to the changes in the dynamic biomechanical environment The chondroid plug in the...

Ngày tải lên: 11/08/2014, 17:20

... a bicycling accident The femoral neck fracture was pinned, and the tracks are visible both on the radiograph and in the intraoperative photograph (insert) Note the extensive defects in the femoral ... osteoarthritis of the hip joint in Japan Clin Orthop 241:190–196 26 Hoaglund FT, Yau AC, Wong WL (1973) Osteoarthritis of the hip and other joints in southern Chinese in Hong Kong J Bone Joint Surg 55A(3):545–557 ... technique [31] resulted in a significant improvement in the initial stability and durability of the prosthesis by eliminating the cases of early femoral component loosening These latter results suggest...

Ngày tải lên: 11/08/2014, 17:21

... bone–implant interfaces in the Gruen zones and [26] Only 0.5% of radiolucent lines in these zones were found in the Bicontact multicenter study of 553 implantations in four German institutions [27] The ... (9 hips) In no instance, however, was the femoral head replaced into the true acetabulum The indication for THA was pain in the dislocated hip, associated with stiffness and limitation in activity, ... The dissection of the inferior part of the elongated capsule led to the true acetabulum, which was exposed properly by a hooked retractor inserted beneath the inferior margin The acetabulum then...

Ngày tải lên: 11/08/2014, 17:21

... anesthesia, monitoring of the spinal cord potential (SCP) is recommended At each step of the operative procedure, the shape and the height of the SCP waves are checked If there is no change in the ... if the strength of the bone is unknown The cerclage system could even cut into the bone while attempting to reach a certain level of tension I would rather rely on my own feeling in judging the ... to use the split metal cylinder to measure the strength of fastening by measuring the amount of displacement in the split at varying loads We believe this is the most reproducible and clinically...

Ngày tải lên: 11/08/2014, 17:21

... transmembrane (TM) domain Binding of the surface subunit gp120 to CD4 and a co-receptor on the T-cell surface triggers conformational changes in the Env complex, leading to the insertion of the ... the C4 region in gp120 have the ability to suppress the T20 inhibitory effect either by preventing T20 from binding to the C4 region in gp120 and/or by modulating gp41 conformational changes via ... scale) with the location of the original GIA-SKY mutations and the second site changes selected in the evolution cultures The G431R change that was selected in multiple cultures is marked in bold...

Ngày tải lên: 13/08/2014, 09:20

... are facing a television campaign that uses humor to present a serious message A group has gathered what it calls "a wealth of information" about the political and criminal activities of the American ... As the economy has changed, major new employers are companies like Wal-Mart WalMart says unions are not needed in its stores It says it does not need a “middle man” in its relationship ... American labor movement The Center for Union Facts says it is supported by foundations, businesses, union members and the general public It does not name its supporters And that's the VOA Special English...

Ngày tải lên: 14/08/2014, 21:21

... tin mining involved the elite while cattle rearing and trade involved the masses Foreigners participated in the tin-cattle economy too, namely the Straits Chinese and the British in tin mining ... nineteenth century.58 Late nineteenth century writers referred to the mines in Sai as the Tomoh/Temoh Mines or the Telubin mines (the valley in which the Tomoh mines were located).59 Gold in the ... Foreign mining companies and individuals were attracted to invest in the Bannang Sata tin fields in the early part of the twentieth century, following the movement away from the depleted mining areas...

Ngày tải lên: 16/09/2015, 17:11