cognitive functions in euthymic bipolar patients and lithium

... to examine brain choline in basal ganglia studied only patients, all of whom were on lithium [18] Another study examined 19 euthymic inpatients and found increased choline/creatine ratios in basal ... increased choline/creatine ratios in the patients before lithium treatment This latter finding does not suggest that in patients lithium significantly alters the choline/creatine ratio The final ... circumstances In one study in 11 bipolar children patients were examined before and after lithium administration [14] There were no significant findings before or after lithium administration,...

Ngày tải lên: 08/08/2014, 20:23

... of cytokine-induced insulin resistance in obesity and other inflammatory settings Curr Opin Clin Nutr Metab Care 2002, 5:377-383 15 Marik PE, Raghavan M: Stress-hyperglycemia, insulin and immunomodulation ... pre-existing increased insulin resistance and dysfunction of beta cells Insulin resistance is present in the acutely ill [13,15,18,28] in different intensity, but the factors determining the extent ... conceived and organized the study, participated in patients' inclusion and follow-up, performed statistical analyses, analyzed results and wrote the manuscript AVB and VG participated in patients' inclusion...

Ngày tải lên: 25/10/2012, 10:02

... Case and control groups were both examined by an expert ophthalmologist and routine ophthalmic examinations including visual acuity determination, slit lamp examination, ophthalmoloscopy and intraocular ... cataract In: Tasman W, Jaeger A, eds Duane’s Clinical Ophthalmology Philadelphia: Lippincott-Raven publishers, 2000:12-14 Kahn HA, et al The Framingham eye study I Outline and major prevalence findings ... alterations in blood, may be the intervening ones [29] Multiple studies have been done to clarify the relationship between human biochemical elements and cataract formation Interestingly in some...

Ngày tải lên: 03/11/2012, 09:49

... in the injured brain has not yet been investigated We sought to determine the interrelationship between intracranial TNF and IL-18 levels in a clinical study on patients with severe CHI and in ... 0.05 in three patients (# 2,5,10) and P < 0.01 in four patients (# 1,4,6,9; Table 1) Since the quality of the blood-brain barrier has not been determined in this cohort of head-injured patients, ... Baseline CHI WT CHI TNF/LT- -/- vehicle injection TNF injection Intracerebral IL-18 concentrations in mice, as determined by ELISA in murine brain homogenates (n = 10 animals per group) Figure Intracerebral...

Ngày tải lên: 19/06/2014, 22:20

... both in monomeric (active) and dimeric (inactive) state [16] The protein contains several important domains such as 1) the C-terminal protein kinase domain (PI3K-domain), 2) the substrate binding ... substrate binding domains, Leucine zipper, ATP-binding domains, FAT domain and PI3K domain [17] together with exonic information (The size of the exons and the distance between them are not indicative ... the domains of the protein described by [17], such http://www.ro-journal.com/content/2/1/25 as the PI3K domain, substrate binding domains and ATPbinding domains, is illustrated in Figure Single...

Ngày tải lên: 09/08/2014, 10:21

... involved in the acquisition of data and was involved in drafting the manuscript MT was involved in the statistical analysis and the interpretation of data and helped to draft the manuscript TE was involved ... the manuscript TE was involved in the genetic analyses and was involved in drafting the manuscript KZ was involved in the genetic analyses and was involved in drafting the manuscript MN made substantial ... al investigated the relationship between several SNPs in the G72 region and select cognitive measures in attention, working memory, and episodic memory in a cohort of over 600 subjects, including...

Ngày tải lên: 11/08/2014, 17:20

... 2207 patients admitted to medical ICU 385 with a history of DM, IFG or IGT 1822 274 died in hospital 1548 screened 443 excluded - 211 refused participation - 203 terminally ill - 29 receiving ... treatment 193 47 IGF / IFG 33 DM 113 normoglycaemic Figure Flow diagram showing the loss of patients from initial screening to the end of five-year follow-up ... started follow-up 102 died 154 discontinued follow-up 15 started steroid treatment 389 49 IGF / IFG 14 DM 326 normoglycaemic finished follow-up 66 died 93 discontinued follow-up started steroid treatment...

Ngày tải lên: 13/08/2014, 21:21

... monitoring It has been recommended to maintain lithium levels between 0.6 and 0.8 mEq/L in this setting [42] Lithium may be used in patients on hemodialysis (HD) and should be administered in a single ... influencing obesity in bipolar patients include nutrient intake and physical activity In assessing the nutrient intake of persons with bipolar disorder, Elmslie and colleagues found that they had increased ... guidelines are being formulated to aid clinicians in identifying patients at risk Screening for diabetes should include questioning patients about symptoms such as excessive thirst and urination,...

Ngày tải lên: 25/10/2012, 10:51

... distinguishing between patients with and without cognitive impairment In sum, the SCIP produced a valid quantification of cognitive status in bipolar patients by psychiatrists with minimal training ... cognitive assessments into the routine clinical examinations of bipolar patients A relative paucity of routine cognitive assessments in current clinical practice is apparent, however, and this may relate ... SCIP and the neurocognitive battery not cover all potentially relevant cognitive domains Also, sensitivity to change remains unexplored Conclusion: With minimal training, physicians obtained...

Ngày tải lên: 18/06/2014, 19:20

... Additionally, our findings indicate that a large percentage of these patients are cognitively impaired and that lower mental status in these patients places them at increased risk for developing behavioral ... to the patients in the study assessed history of substance abuse and psychiatric illness, by both obtaining information from the patient themselves and by reviewing patient charts We also included ... studies that investigated cognitive impairment in an acute care setting observed a similar prevalence Hickey et al., in an investigation of 112 older patients in the acute care setting, average...

Ngày tải lên: 08/08/2014, 20:23

... bovine serum (GIBCO) and a mixture of penicillin-streptomycinglutamine (PSG from GIBCO) Puromycin-resistant MEF lines were grown, maintained, serum shocked, and serum starved in medium containing ... JR: Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells Curr Biol 1996, 6(12):1664-1668 Ryves WJ, Harwood AJ: Lithium inhibits glycogen synthase kinase-3 ... of lithium, (iv) the direct inhibition of GSK3 by lithium in vivo and in vitro, and (v) the role of Sgg/GSK3 in the modulation of period length in fruit fly and murine clocks, places GSK3 at the...

Ngày tải lên: 10/08/2014, 09:20

... language functions (speaking, reading, and writing) – symptoms include: difficulty in thinking of common words while speaking, hesitations; speech, spelling, and writing errors e Changes in personality, ... Impaired reasoning and handling of complex tasks, poor judgment – symptoms include: poor understanding of safety risks, inability to manage finances, poor decisionmaking ability, and inability to ... (including table formatting) Thank you for keeping me in line and standing by my side IV Contents Abstract Introduction 2.1 Dementia and Alzheimer’s disease (AD): Definition...

Ngày tải lên: 26/11/2015, 10:00

... correlated both during PLR and following VE [30] Lafanechère and colleagues examined 22 intubated and fully sedated patients with an esophageal Doppler monitor in place [31] An increase in aortic blood ... sensitivity of 97% and specificity of 94% Boulain and colleagues studied 39 patients with a PAC and radial arterial line in place, and found that the change in pulse pressure and SV were significantly ... of the attending physician and included normal saline, Ringer's lactate and hetastarch The volume administered in each case was at least 500 ml, and was given as a pressurized rapid infusion Vasopressor...

Ngày tải lên: 25/10/2012, 10:06

... to 14 patients in the standard insulin group (5.6%) and 14 in the intensive insulin group (5.5%) The remaining patients received total-enteral feeding exclusively In the standard insulin group ... 250) in the standard insulin group and 36.6% (93 of 254) in the intensive insulin group ICU mortality was similar for patients of the standard insulin group and in those from the intensive insulin ... USA) The standard concentration of insulin (Humulin R, Eli Lilly and Company, Indianapolis, IN, USA) was 100 units in 100 ml of 0.9% saline solution In the standard insulin group, insulin infusion...

Ngày tải lên: 25/10/2012, 10:35

... fixed in buffered formalin, embedded in paraffin, and stained with hematoxylin-eosin-safran and Masson's trichrome Hepatic steatosis, stage of fibrosis and grade of disease activity were determined ... of clinical and pathological characteristics in these patients with steatosis and their diagnostic values in hepatic fibrosis Patients and methods Patients A total of 204 HBeAg-negative CHB patients ... Research and Therapy Center for Liver Diseases of China Southeast Hospital from May 2005 to March 2009 Most patients did not drink alcohol, and alcohol consumption in the remaining patients was...

Ngày tải lên: 25/10/2012, 11:48

... of a combination of a calcineurin inhibitor (tacrolimus) with a purine inhibitor (mycophenolate mofetil or azathioprine) and a steroid (prednizolone) Tacrolimus was given twice a day in individually ... Hesselink DA, van Schaik RH, van der Heiden IP, et al Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus Clin ... seriousness, co-administrated drug therapies and their interactions, renal and hepatic function, nutritional and other habbits, are often responsible for the intra- and inter-individual variability...

Ngày tải lên: 26/10/2012, 09:32

... serum obtained from patients with positive IgG cardiolipin antibodies interfered with protein C activation [2] Protein C activation is disturbed in patients with APS [17] Since protein C is closely ... antibodies in ischemic stroke patients Intern Med 2006; 45: 1017-8 Diz-Kucukkaya R, Hancer VS, Artin-Esen B, et al The prevalence and clinical significance of inherited thrombophilic risk factors in patients ... The cumulative incidence of stroke in patients with single antiplatelet treatment was higher than that in patients receiving the combination of antiplatelet and anticoagulation therapy (log-rank...

Ngày tải lên: 26/10/2012, 09:48

... alone and combined therapy of inhalation and antibiotics decreased P aeruginosa load in sputum Previous studies used hypertonic saline solution or mannitol as inhalation treatment in CF (11-14) Inhalation ... to other inhalations (eg hypertonic saline) In conclusion the findings in this report show that inhalation with fucose/galactose solution could reduce P aeruginosa in sputum of adult CF patients ... chronic infection with P aeruginosa as at least the PA-II acts on cilia of CF patients in vitro in the same way as in normal controls (8) twice with PBS containing 2% FCS PMBC were counted, cytospins...

Ngày tải lên: 03/11/2012, 11:48

... lack of increase in LV dyssynchrony during dobutamine stress in patients with wide QRS duration (20) In contrast, Kurita et al reported on an increased mechanical dyssynchrony during pacing–induced ... were receiving a beta-blocking agent, 30 an angiotensinconverting enzyme inhibitor or angiotensin receptor blocker, and 19 a diuretic In patients with conduction disturbance, 13 of 17 patients ... heterogeneous termination LV isovolumic 338 time intervals were found to be increased at the expense of LV diastolic time in heart failure patients (17,18) Since our findings and other previous...

Ngày tải lên: 05/11/2012, 11:32

... Initialing Local Variables in T-SQL To initialize the variables, you will use the SET command, shown in these two lines of code: SET @Cust_Id = 'ANTON' SET @Order_Date = '11/27/1996' By setting ... the initial values, you are then ready to use the variables within the rest of your procedure, any way that you need them, again, by using the @varname syntax Utilizing Built -In Functions Within ... a Windows Form Then place the controls listed in Table 6.2 and seen in Figure 6.3 with the following properties set Table 6.2 Control Property Settings for This How-To Object Property Setting...

Ngày tải lên: 14/12/2013, 20:16