... necessary and sufficient for the induction and progression of fibrotic lesions, and may serve as the initiating event in the activation of myofibroblasts, which then secrete a large amount of extracellular ... examined the correlation between lipogranulomas and fibrosis, and speculated the origin of brown pigments of lipogranulomas Results Histopathology of the liver Histopathological diagnoses of the 52 ... coefficients were used to test the association between the density of lipogranuloma and distribution of collagen type I/III, and to investigate the origin of brown pigments of lipogranulomas [24] P...
Ngày tải lên: 13/08/2014, 13:20
... Second Law of Thermodynamics For them, the origin of life is nothing more or less than the emergence of sufficient biological information to enable a system of biopolymers to (1) store information, ... account for the diversity of life in the biosphere, it is generally recognized that the origin of life is one of the great unsolved mysteries in science (Radetsky1992; Wade 2000) At the heart of this ... are able to sustain themselves against the downward pull of the Second Law of Thermodynamics and how thermodynamics affects the origin of information-rich, living systems Finally, we will explore...
Ngày tải lên: 01/11/2013, 07:20
THE SUSTAINABLE DEVELOPMENT OF TREE CROPS AND THE PREVENTION OF VEGETATION FIRES IN SOUTH SUMATRA, INDONESIA pptx
... limited extent, the size of the area burnt - and the matching of these with maps of land-use This indicated that most serious and persistent fires originated in logging concessions and agro-industrial ... Thus the rigid dichotomy often presumed between forest and plantation is irrelevant to the understanding and management of such land-use systems The recent changes of status of the Ministry of ... search of new land, others remained and started to replace their old rubber using the technique used to create the original plantation The sale of latex provides 80 percent of the income over the...
Ngày tải lên: 08/03/2014, 10:20
hancock - plant evolution and the origin of crop species 2e (cabi, 2004)
... sequences on the DNA (Fig 1.14) The polymerase enzyme then synthesizes the DNA strand next to the primers The solution is then heated and cooled in numerous cycles, and the DNA is amplified over and over ... is the frequency of one allele (A) in a population and q the frequency of another (a), then p + q = when there are no other alleles The equilibrium frequencies of the genotypes are given by the ... framework of species change and demonstrate the intimacy of nature and crop evolution In the second half of the book, I focus on when and where crops were domesticated and the types of changes...
Ngày tải lên: 03/04/2014, 12:10
báo cáo khoa học: " DNA sequence diversity and the origin of cultivated safflower (Carthamus tinctorius L.; Asteraceae)" ppsx
... detected by the presence of double peaks and coded following the conventions of the International Union of Biochemistry and Molecular Biology From these, haplotypes were resolved using the maximum ... native to the deserts of southern Israel and western Iraq, is the wild progenitor of safflower Safflower and C palaestinus share a self-compatible breeding system [12]; thus, the near absence of heterozygous ... stocks (Fig 2) Further investigation of the 'seven centers' hypothesis, will require the development and application of more variable markers to a much more robust sampling of the available safflower...
Ngày tải lên: 12/08/2014, 05:20
The Evolving Universe and the Origin of Life
... Egypt The appearance of the “Dog Star” in the morning sky heralded the beginning of the flood of the river Nile Just across the band of the Milky Way there is Procyon, the brightest star of the ... to the Sun and to the Moon, and (b) the sizes of the Sun and the Moon, using the Earth radius as a unit The latter method (b) was based on the eclipse of the Moon (using the shadow cast by the ... 397 Origin of the Earth as Part of the Solar System, a Modern View 400 The Early Earth and the Origin of the Moon 402 Evolution of Earth and the Relevant...
Ngày tải lên: 31/05/2016, 20:51
Báo cáo khoa học: Nitric oxide formation from the reaction of nitrite with carp and rabbit hemoglobin at intermediate oxygen saturations pdf
... that the production of HbNO depended on So2, the species-specic O2 afnity (carp against rabbit) and the relative stabilization of the T state versus the R state of Hb (presence and absence of ATP) ... max (àM) The addition of ATP to stabilize the T state and to impede the T to R transition caused the disappearance of the well-dened peak for the deoxyHb reaction rate and decreased the absolute ... result in the formation of HbNO in excess of metHb, but subsequently the concentrations of reaction products increased in parallel, and at the end of the experiment, both HbNO and metHb were...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Mercury(II) binding to metallothioneins Variables governing the formation and structural features of the mammalian Hg-MT species pptx
... on the effect of two variables, the reaction time and the presence of chloride ions, on the stoichiometry, stereochemistry and degree of folding of the Hg(II)-MT species formed by either the ... of all the variables in the Hg-MT system required the performance and analysis of 18 Ó FEBS 2004 titrations and the corresponding duplicates The detailed and comparative analysis of the set of ... Notwithstanding this, there is a minor effect of t and X at the beginning and end of the titration Thus, the addition of the first 4–6 of Hg(II) to apo-MT gives rise to Hg-MT species of comparable...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Sequences and structural organization of phospholipase A2 genes from Vipera aspis aspis, V. aspis zinnikeri and Vipera berus berus venom Identification of the origin of a new viper population based on ammodytin I1 heterogeneity docx
... 3, and the 5¢ part of exon encode the mature protein; exon encodes the 5¢-UTR, and exon and part of exon encode the signal peptide The 110 nucleotides at the 3¢ end of exon encode the 3¢-UTR The ... Ib in the genome of this snake These findings provide clues to the evolutionary position of the neurotoxic V a aspis population with respect to the other snakes studied The genome of one of these ... stabilize the structure of the molecule Six of these residues were substituted (Fig 3), probably decreasing the stability of the molecule by preventing the formation of disulfide bonds Toxicity and...
Ngày tải lên: 17/03/2014, 03:20
A Philosophical Inquiry Into The Origin Of Our Ideas Of The Sublime And Beautiful
... pain and danger, they not dwell on the pleasure of health and the comfort of security, and then lament the loss of these satisfactions: the whole turns upon the actual pains and horrors which they ... scorneth the multitude of the city, neither regardeth he the voice of the driver The range of the mountains is his pasture The magnificent description of the unicorn and of leviathan, in the same ... Imitation, and Ambition 13 Sympathy 14 The Effects of Sympathy in the Distresses of Others 15 Of the Effects of Tragedy 16 Imitation 17 Ambition 18 The Recapitulation 19 The Conclusion Part II Of the...
Ngày tải lên: 18/03/2014, 11:11
Báo cáo khoa học: Monitoring the prevention of amyloid fibril formation by a-crystallin Temperature dependence and the nature of the aggregating species pdf
... 2.5 h, the thickness increased by 0.212 nm, the mass increased by 0.05 ngÆmm)2 and the density decreased by 0.0167 gÆcm)3, from the start of the experiment By the end of the measurement, the thickness ... fluorescence The subsequent plateau phase is associated with a decrease in the concentration of small species, or the aggregation and precipitation of fibrils [37] The kinetics of these three stages of the ... amyloidogenic nucleus and other prefibrillar intermediates, culminating in formation of the mature fibril [24] The increasing a-Crystallin and amyloid fibril formation complexity of these structures...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase pptx
... the iron and the guanidinium moiety was fixed by an H-bond between the proton of N2 and the backbone oxygen of Gln310 (Fig 3) This conformation of BH4 coincided with the ˚ conformation of BH4 in ... study using the program DOCK 4.0 [37] to model the conformation of BH4 and a series of pterin analogs placed into the crystal structure of the TH catalytic domain [15] On the other hand, equivalent ... monodentate and other binding modes to be included in further analysis Results Pterin binding to the catalytic domains of PAH and TH Docking of the native cosubstrate BH4 into the crystal structure of the...
Ngày tải lên: 31/03/2014, 07:20
Báo cáo Y học: Ascidian arrestin (Ci-arr), the origin of the visual and nonvisual arrestins of vertebrate pdf
... on the nucleotide sequence of the PCR products, specific primers were synthesized and used for 5¢- and 3¢-RACE Based on the sequence of 5¢- and 3¢flanking region of ORF of Ci-arr (Ar-full-N (5¢-CTGT ... 2002 Origin of vertebrate visual and nonvisual arrestins (Eur J Biochem 269) 5115 Comparison of two types of cDNA and genomic DNA revealed that splicing of intron 11 resulted in the shift of the ... sense organ and the posterior pigment is ocellus (OC) The expression of Ci-arr is restricted to the photoreceptors in the right side of the OC Fig Phylogenetic tree of arrestin family The molecular...
Ngày tải lên: 31/03/2014, 08:20
led zeppelin. the origin of the species how, why and where it all began
... the loftiest plateaux of pop in the teeth of adult disapproval of the noise, gibberish and loutish excesses of the rock ‘n’ roll epidemic from across the Atlantic of which Berry was part Furthermore, ... Dave 48 THE ORIGIN OF THE SPECIES - with hired hands quicker off the mark The Cruisers could then learn the song off the record Apart from hurt pride, it wouldn’t matter No-one would be any the wiser ... such as The Outlaws and horror-rock specialists, Screaming Lord Sutch and the Savages as well as Dave Dee and the Bostons, The Rockin’ Berries, Johnnie Law and the MI5, Chris Farlowe and the Thunderbirds,...
Ngày tải lên: 04/06/2014, 15:26
Báo cáo sinh học: " Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein" pot
... removal of C2 has only a mild inhibitory effect in the case of NP-NP complex formation and it even enhances binding in the case of the NP-VP35 interaction On the other hand, C2 is essential for the ... and the functions of the protein The binding site of the monoclonal antibody 2B10 on NP was analyzed by Western Blot using internal deletion mutants of NP From the set of tested NP mutants, the ... critical for the homooligomerization of NP, formation of NP-induced intracellular inclusions, interaction of NP with VP35 and for the function of NP in RNA synthesis Materials and methods Cells and cDNA...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx
... clinical disease Taken together, the results of the present study and from previous ones on the role of CCR1 and its ligand CCL3 in the pathogenesis of MS [39,40,42] and EAE [22,44,46], have provided ... crucial for the understanding of therapeutic modulation and the validation of CCR1, CCR2 and CCR5 as feasible targets for therapeutic intervention in MS Background Multiple sclerosis (MS) is the most ... from Finland, suggesting that the lack of CCR5 does not protect from MS, but rather it may predispose to the chronic course of the disease [69] This would further imply that in view of the redundancy...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: " Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein" pdf
... removal of C2 has only a mild inhibitory effect in the case of NP-NP complex formation and it even enhances binding in the case of the NP-VP35 interaction On the other hand, C2 is essential for the ... and the functions of the protein The binding site of the monoclonal antibody 2B10 on NP was analyzed by Western Blot using internal deletion mutants of NP From the set of tested NP mutants, the ... critical for the homooligomerization of NP, formation of NP-induced intracellular inclusions, interaction of NP with VP35 and for the function of NP in RNA synthesis Materials and methods Cells and cDNA...
Ngày tải lên: 20/06/2014, 01:20
from dust to stars studies of the formation and early evolution of stars
... estimate the lifetime of stars by: tlif e = 7.3 × 109 M/M yr L/L (2.2) 2.2 The Quest to Understand the Formation of Stars 21 where M and and L are the mass and luminosity of the Sun and M and L the ... exemplary missions, SOFIA as the successor of the airborne Kuiper Observatory of the 1980s and early 1990s, JWST as the successor of Hubble, and the space probes Herschel and GAIA SOFIA and Herschel ... avoiding the absorbing effects of vapor clouds Herschel then has the rather unique objective of studying the formation of galaxies in the early universe and thus provide information about the formation...
Ngày tải lên: 03/07/2014, 21:09
Báo cáo sinh học: " Darwin and Huxley revisited: the origin of allometry" docx
... and W(s) determine the length and width of the head (L for the vertical axis of the ellipse and W for the horizontal axis) Note that the values of L(s) and W(s) depend on the size s; when L(s) ... proclaimed the death of Darwinism.” ‘Darwinism’ here refers to the random heritable variation and natural selection parts of the theory, not the idea of evolution itself One of the popular alternatives ... 104:12931-12935 Darwin CR: Journal of Researches into the Natural History and Geology of the Countries Visited During the Voyage of H.M.S Beagle Round the World, Under the Command of Capt Fitz Roy, R.N 2d...
Ngày tải lên: 06/08/2014, 18:21
Báo cáo khoa học: "Mucin pattern reflects the origin of the adenocarcinoma in Barrett''''s esophagus: a retrospective clinical and laboratorial study" ppsx
... adjacent to the tumors There was an association between the predominance of mucin expressed in the adjacent epithelium and the pattern of mucin expression in the tumors, may indicating the route of carcinogenesis ... Table shows the relationship between mucin pattern predominance in the adjacent epithelium compared to the mucin tumour expression Discussion The extension of the columnar epithelium in the esophagus ... inflammatory lesions and regeneration Thus, all cells of the BE under damage could originate an expansion clone capable of initiate the carcinogenesis cascade The pattern of expression of mucin gene...
Ngày tải lên: 09/08/2014, 04:21