... regulation of GSK3 and GS To further understand the effects of Li and SB-415286 on cell signalling events we assessed their effects and that of insulin on p70S6K, PKB, p42/p44 MAP kinases, GSK3 and ... muscle and fat cells To gain some insight into this issue we subsequently monitored the effects of a number of inhibitors that target PI3K, the MAP kinase pathway, p38 MAP kinase and mTOR on ... Regulation of GS activity To establish the importance of GSK3 inhibition on GS activity we monitored the effects of insulin, Li, SB-415286 and wortmannin (a PI3K inhibitor) on the incorporation of Ó...
Ngày tải lên: 08/03/2014, 08:20
... concentration of cytosolic biliverdin-IXa The paucity of information on the biliverdin binding site has hampered the development of inhibitors of BVR-A With this in mind, and in the absence of a crystal ... reported to form adducts with environmental toxins [15] and endogenous ligands [16] BVR-B is adducted at equimolar stoichiometry by electrophilic metabolites of 1-nitronapthalene [15] and BVR-A ... (v ⁄ v) methanol from the stock solution of ester (blue); addition of 37 lM BSA from a stock solution of 50 mgÆmL)1 produced the red trace and subsequent addition of 50 lM NADPH produced the...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: "Early results on the use of biomaterials as adjuvant to abdominal wall closure following cytoreduction and hyperthermic intraperitoneal chemotherapy" ppt
... concomitant use of chemotherapy and hyperthermia which are both known to increase cellular death and induce apoptosis [6,7]; second, tumor cytoreduction may require surgical resection of involved ... laparotomy incision Lysis of adhesions, when needed was performed, followed by assessment of the intraabdominal extent of the disease and the peritoneal cancer index (PCI) Appropriate cytoreductive ... The inflow and outflow tubes were secured to the skin and connected to a cardiopulmonary bypass pump (Figure 3) A temperature needle probe was placed into one of the outflow catheters and the skin...
Ngày tải lên: 09/08/2014, 03:22
scala how to make best use of functions and objects
... language, it has many of the characteristics of popular dynamic languages, through its rich and flexible type system, its sparse and clean syntax, and its marriage of functional and object paradigms.” ... Another reason: libraries are much easier to extend and adapt than languages Experience: Initial versions of actors used one thread per actor ⇒ lack of speed and scalability Later versions added a ... removes some of the more arcane constructs of these environments and adds instead: (1) a uniform object model, (2) pattern matching and higherorder functions, (3) novel ways to abstract and compose...
Ngày tải lên: 24/10/2014, 13:47
use of ontologies and probabilistic relational models to aid in cyber crime investigation decision support
Ngày tải lên: 14/11/2014, 08:59
Báo cáo y học: "Use of chinese and western over-the-counter medications in Hong Kong"
... incentives and support like such as remuneration should be considered [20] Other factors such as proximity to other professionals, opportunity for inter-professional communication and access to patients’ ... essential to integrate pharmacists in the primary care system [20] The role of medical professionals is a dominant factor in defining, controlling and scoping the work of the allied health professionals ... aged, to have no insurance coverage for WMD services, and to suffer from chronic diseases Discussion and recommendations A total of 50.8% of the Hong Kong population used western OTC medication...
Ngày tải lên: 25/10/2012, 10:06
Customer satisfaction: review of literature and application to the product-service systems
... shopping, and psychographic portrait of customers A number of drawbacks and benefits pertaining to the tools have been pointed out and discussed Both the research models and the tools, while diverse to ... measuring customer satisfaction excluded practical advice on how to develop these tools and how to analyse collected data, due to the general nature of these tools and availability of sources, ... functional value, conditional value, social value, emotional value, and epistemic value Changes of values are usually explained from a life-cycle perspective (people grow older and their values change)...
Ngày tải lên: 04/11/2013, 10:15
Tài liệu Evolution of GSM and cdmaOne to 3G Systems pptx
... system It had to fight to be born because of the lack of spectrum, and the quasi-religious attitudes 406 CHAPTER EVOLUTION OF GSM AND CDMAONE TO 3G SYSTEMS of engineers towards methods of multiple ... codes to prevent the crest factor, i.e the ratio of the peak -to- mean transmitted power, from becoming too high The crest factor is allowed to be up to 18 dB We recall that in the presence of multiple ... 6, 12 and 14.5 kb/s for a code 422 CHAPTER EVOLUTION OF GSM AND CDMAONE TO 3G SYSTEMS rate of 0.16, 0.26, 0.53 and 0.64, respectively; while for 8-PSK the bit rates have the higher values of 14.5,...
Ngày tải lên: 23/12/2013, 17:15
Tài liệu The Game of Life and How to Play It pdf
... mind with a picture of lack and limitation A situation of lack may be changed to one of plenty Fortunately the law works both ways, and a situation of lack may be changed to one of plenty For example: ... mind, body and affairs It is safe to say that all sickness and unhappiness come from the violation of the law of love A new commandment I give unto you, “Love one another,’’ and in the Game of Life, ... go, and take your mental hands off; put it in God’s Hands, and use this statement: I put this situation in the hands of Infinite Love and Wisdom; if this trip is the Divine plan, I bless it and...
Ngày tải lên: 24/12/2013, 09:17
Tài liệu TREES OF THE NORTHERN UNITED STATES THEIR STUDY, DESCRIPTION AND DETERMINATION FOR THE USE OF SCHOOLS AND PRIVATE STUDENTS doc
... H Redfield, of the Botanical Department of the Philadelphia Academy of Natural Sciences, for books, specimens from which to make illustrations, etc.; and to Dr A C Stokes, of Trenton, New Jersey, ... the pile of plants and paper On account of the size of many leaves and flowerclusters, these pressed specimens of trees should not be shorter than from 12 to 15 inches, and even a length of 18 inches ... little study of the roots of trees is practicable, some knowledge of their forms, varieties, and parts is important The great office of the roots of all plants is the taking in of food from the...
Ngày tải lên: 13/02/2014, 12:20
Tài liệu Guideline on Network Security Testing: Recommendations of the National Institute of Standards and Technology ppt
... include signal handling and core-file manipulation + File and Directory Permissions—File and directory permissions control the access users and processes have to files and directories Appropriate ... operations and assets, but such standards and guidelines shall not apply to national security systems This guideline is consistent with the requirements of the Office of Management and Budget ... voluntary basis and is not subject to copyright though attribution is desired by NIST Nothing in this document should be taken to contradict standards and guidelines made mandatory and binding on...
Ngày tải lên: 14/02/2014, 08:20
Tài liệu THE USE OF STUDENTS AND TRAVELLERS pptx
... Dynasty 156 Plan of tomb of Rameses IV 157 Plan of tomb of Rameses IV., from Turin papyrus 158 Plan of tomb of Seti I 159 Fields of Aalỷ, wall-scene, tomb of Rameses III 160 Pestle and mortar for ... of Pyramids, Orientation, Pyramid of Khỷfỷ, Pyramids of Khafra and Menkara, Step Pyramid of Sakkarah, Pyramid of nas, Decoration of Pyramid of nas, Group of Dashỷr, Pyramid of Medum Đ TOMBS OF ... ROCK-CUT TOMBS: Pyramidmastabas of Abydos, Pyramid-mastabas of Drah Abỷ'l Neggah, Rock-cut Tombs of Beni Hasan and Syene, Rock-cut Tombs of Siỷt, Wall-decoration of Theban Catacombs, Tombs of the...
Ngày tải lên: 15/02/2014, 09:20
Tài liệu Smart Posters - How to use NFC tags and readers to create interactive experiences that benefit both consumers and businesses docx
... entrances of the mall Users touch their NFC-enabled handsets to NFC Smart Posters to opt in and receive the day’s special offers The relevant special offers are matched to the user’s profile so ... the world to date, the Citi “Tap and Pay” pilot project in India, NFC Smart Posters were used to deliver coupons and promotions to participants targeted to their locations and personal profiles ... graphic is expected to be the globally recognized touchpoint indicator It should be printed over each touchpoint to indicate the site of the optimal user experience (the place to touch with the reader...
Ngày tải lên: 21/02/2014, 05:20
Tài liệu Chief, Management and Organization Division National Institute of Standards and Technology pptx
... analysis by NIST would lead to improper building codes, standards and practices These improper building standards could, in turn, lead to needless deaths if such standards are too lenient, or unnecessary ... was calculated to exit the side opposite to impact and most of the debris was stopped prior to reaching that side, in contradiction to what was observed in photographs and videos of the impact ... finding out how and why the buildings completely and totally failed to stand - 22 - The bias of the WTC Report is perhaps the most violative of any of the information quality standards The WTC...
Ngày tải lên: 21/02/2014, 12:20
USE OF HEALTH AND NURSING CARE BY THE ELDERLY pptx
... 60 and older and those reporting a bad or very bad health status aged 15 to 44 and 60 to 79 were more often hospitalised in 2001 The probability of hospitalisation increased with age too In total ... care-giving and changes in the labour force participation of women over time; analyse the contribution of the elderly to the care and nursing of the oldest old; and provide data on the rules and regulations ... Survey Use of health care The aim of this section is to analyse the current use of health care services by the elderly and the determinants of this utilisation Indicators for the use of health...
Ngày tải lên: 05/03/2014, 18:20
REPORT ON THE OBSERVANCE OF STANDARDS AND CODES (ROSC) Cambodia docx
... support and cooperation to facilitate the process of setting standards Mobilize funding and technical expertise in order to ensure that the accounting and auditing standards are up to date and to ... timely adoption of standards, updating Cambodian standards based on changes in the international standards, and issuing guidance with respect to practical application of these standards For example, ... auditing standards, no modifications are made to the International Standards on Auditing The National Accounting Council has adopted 15 accounting standards and 10 auditing standards Draft standards...
Ngày tải lên: 06/03/2014, 21:20
Direct HFC and PFC Emissions from Use of Refrigeration and Air Conditioning Equipment pptx
... Protocol consists of corporate accounting and reporting standards and separate calculation tools The Climate Leaders Greenhouse Gas Inventory Protocol is an effort by EPA to enhance the GHG Protocol ... inventory of equipment Determine the number and types of fire sup pression equipment, by gas type, and the charge capacity of each piece of equipment where: CD = charge capacity of the piece of ... inventory of equipment Determine the number and types of refriger ation and air conditioning equipment (by equipment category, see Section 4.1) includ ing the types of refrigerant used and the total...
Ngày tải lên: 08/03/2014, 19:20
the situation of dolllarization in vietnam, it impacts on accounting system and economy of vietnam and actions to fight its
... quarter of 2011, the State Bank of Vietnam decided to reduce the saving interest of U.S dollar Instead of 6% to 7% per year, the State Bank of Vietnam decided to reduce saving interest of USD to 2% ... determination of this exchange rate as to reduce the dependence of the Vietnam dong into U.S dollars, and reflect more authentic relationship of supply and demand in the market on the basis of taking into ... prices will increase profit per unit of product sold, and if other factors constant, the sum of their profits will rise, encouraging investors to open wide production, contribute to reducing unemployment...
Ngày tải lên: 13/03/2014, 14:20
Adolescents’ Use of Maternal and Child Health Services In Developing Countries pdf
... the end of DHS-II surveys and the beginning of DHS-III and DHS+ surveys, thus allowing us to use similar Adolescents’ Use of Maternal and Child Health Services TABLE Year of Demographic and Health ... their use of antenatal care, delivery care and infant immunization services relative to that of older women, taking into account factors that may mediate the relationship between age and use of services ... policy and programs, in: Beijing +5 Meeting, New York: UNFPA, 2000; and Mathur S, Greene M and Malhotra A, Too Young to Wed: The Lives, Rights, and Health of Young Married Girls, Washington, DC:...
Ngày tải lên: 14/03/2014, 11:20
Use of algae and aquatic macrophytes as feed in small-scale aquaculture
... Pádua, Fontoura and Mathias (2004) Pádua, Fontoura and Mathias (2004) Pádua, Fontoura and Mathias (2004) Msuya and Neori (2002) Appler (1985) Boyd (1968) Pine, Anderson and Hung (1989) Appler and Jauncey ... open waters, one kind of seaweed is either forced into the soft sediment on the sea bottom with a fork-like tool, or held in place on a sandy bottom by attaching it to sand-filled plastic tubes ... cultures of Euglena elongata and Chlorella ellipsoidea were fed to them These authors concluded that the mortality of tilapia fry might be due to factors such as toxicity and cell-wall composition of...
Ngày tải lên: 14/03/2014, 11:21