clinical trials — clinical assessments of product safety and performance

... Rehabilitation and Research Centre, University of Oulu, FIN-, Finland Axel Urhausen Institute of Sports and Preventitive Medicine, Department of Clinical Medicine, University of Saarland, D-, Saarbruecken, ... interdependent and capable of adaptation, apparently with the overall objective of minimizing discomfort and thereby enhancing performance Ventilatory demands of exercise The major demand on ventilation ... of Jyvọskylọ, FIN-, Finland Timo Sọppọlọ National Public Health Institute, Helsinki, FIN-, Finland Timo Takala Department of Biology of Physical Activity, University of Jyvọskylọ, FIN-, Finland...

Ngày tải lên: 15/03/2014, 09:20

... visiting professor at the Universities of Cape Town, Tel Aviv, and Lyon, and at the Pasteur and Weizmann Institutes He is a fellow of the American Association for the Advancement of Science and of the ... He is a member of numerous professional societies and has been on the editorial boards of The American Journal of Physiology, The Journal of Nutrition, and The American Journal of Clinical Nutrition ... Health and Disease, John J.B Anderson and Sanford C Garner Edited by Ira Wolinsky Published Titles Practical Handbook of Nutrition in Clinical Practice, Donald F Kirby and Stanley J Dudrick Handbook...

Ngày tải lên: 28/03/2014, 22:20

... confidence and an understanding of the modalities and the individual patient responses began to crystallize and fall into predictable patterns, the frequency of inquiry abated There were many trials and ... systems, mind and body, and body and soul The human whole is more than the sum of his or her parts and cannot be meaningfully dissected to understand the whole One is reminded of the story of the blind ... Much the same sort of energy transfer is seen in the voodoo cult of Haiti and in the laying on of hands and the effect of prayer, albeit negative energy in the first instance and positive in the...

Ngày tải lên: 29/03/2014, 07:21

... quality of life in a clinical sample of obese children and adolescents Health and Quality of Life Outcomes 2010 8:134 Submit your next manuscript to BioMed Central and take full advantage of: • ... weight and HRQoL We examined pubertal status and its impact on obesity and HRQoL The aims of this study were therefore to: 1) to measure HRQoL in a mixed-ethnic clinical sample of obese children and ... status and ethnicity were used to compare the PedsQL scores of the clinic and the control samples Finally, analysis of covariance was used to investigate the interaction effect of pubertal status and...

Ngày tải lên: 20/06/2014, 15:20

... characterize clinical isolates of M bovis and M tuberculosis isolated from animals and human in India by using IS 6110 and IS 1081 sequence polymorphism based RFLP in order to disclose chain of transmission ... of transmission between human and animals in a restricted geographical location Materials and Methods Mycobacterial strains Details of clinical isolates of M bovis and M tuberculosis used in this ... IS6110 and IS1081 probes The results of RFLP fingerprinting of mycobacterial strains with these probes are shown in Table and Out of 28 field M tuberculosis strains, 27 showed copies of IS6110...

Ngày tải lên: 07/08/2014, 18:20

... aspect of the cuboid and lateral cuneiform bones, with distal attachment on both the medial and lateral sides of the proximal phalanx of the hallux The FHB acts to flex the proximal phalanx of digit ... ages of 18 and 35 were recruited from the student and community populations surrounding a university in Southeastern Michigan A sub-group of 40 participants were Galloway et al Journal of Foot and ... present mean and standard deviation values for all parameters at baseline and at subsequent week, 16 week and 24 week data collection sessions The root mean square error, standard error of the measurement,...

Ngày tải lên: 10/08/2014, 21:24

... obtains economies of scope if joint production of multiple products in the same firm is more profitable or less costly than the production of each product alone in separate firms (Panzar and Willig, ... organizational structure, scope, and performance) (Granstrand and Sjolander, 1990; Argyres, 1996; Granstrand et al., 1997; Gambardella and Torrisi, 1998; Granstrand, 1998; Brusoni et al., 2001) ... Prof Trinh Kim Chi and Prof Peter Hwang for being my mentors in my first two years in the NUS Business School I also want to thank Prof Sai Yayavaram, Prof Chung Chi-Nien, Prof Jane Lu, and Prof...

Ngày tải lên: 09/10/2015, 11:06

... S.K Bhatti, Effect of soybean oil biofuel blending on the performance and emissions of diesel engine using diesel-rk software, International journal of engineering science and technology, 4539-4555, ... suitable for the prediction of the combustion and performance characteristics of the C.I engine and further work is required for modeling engine emissions The combustion and performance results for ... Canakci, ‘Determination of performance and combustion characteristics of a dieselengine fueled with canola and waste palm oil methyl esters’, Int journal of Energy Conversion and Management, volume.52,...

Ngày tải lên: 05/09/2013, 16:11

... vector of observations, b is the vector of fixed effects, p is the vector of random litter effects, a is the vector of random additive genetic values of animals, e is the vector of residuals, and ... number of ancestors and the number of covariance components resulted in a reduction of the number of likelihood functions to be computed and of the CPU time per likelihood The impact of 1) was ... variability of feeding behaviour criteria The aim of the present study was to estimate genetic parameters of the Large White and French Landrace breeds for feeding behaviour criteria and production...

Ngày tải lên: 09/08/2014, 18:22

... better alignment of risk, finance and performance management Interviewees Andrew Burns Chief Strategy Of cer Bank of East Asia Sir David Kwok-po Li Chief Executive Of cer Bank of East Asia Stephen ... alignment of risk, finance and performance management board and executive attention for risk Professor Dermine of INSEAD warns: “It is part of human nature to look at short-term profit and not to ... alignment of risk, finance and performance management of the economy Similarly, Professor Charles Goodhart, director of the Financial Regulation Research Programme at the London School of Economics,...

Ngày tải lên: 06/12/2015, 23:09

... use, and product compliance Visit Visit Visit Visit Randomization Clinical assessments as indicated; first dose in clinic Clinical assessments as indicated Clinical assessments as indicated Clinical ... Canada) Appropriateness of Measurements The efficacy and safety assessments used in this study were standard for OA and are widely used and recognized as reliable, accurate, and relevant WOMAC scores ... common form of arthritis, and it is often associated with significant disability and an impaired quality of life Clinical and radiographic surveys have found that the prevalence of OA increases...

Ngày tải lên: 26/10/2012, 09:48

... platelet count of 9.2 × 104/μL, PT of 37% (PT-INR 1.78), T-Bil level of 11.7 mg/dL, ALT level of 260 IU/L, and serum albumin level of 2.9 g/dL Serum HGF and AFP levels were 1.07 and 3.9 ng/mL, ... preparation of GMP-grade formulation, and useful discussion about the results of preclinical safety tests; and the Intractable Hepato-biliary Disease Study Group of Japan Page 11 of 12 for the ... intravenously for 14 days, and urinary excretion of albumin and protein was measured before (day 1), during (days and 14), and and 14 days after HGF administration Repeated doses of rh-HGF induced an...

Ngày tải lên: 18/06/2014, 19:20

... threshold of less than g/dL, PT of less than 50%, and platelets of less than 50,000/mm3 Fluid management was carried out to achieve to 12 mm Hg of central venous pressure or 12 to 15 mm Hg of pulmonary ... pressure of greater or equal to 70 mm Hg, and dobutamine was titrated to achieve a cardiac index of greater or equal to2.5 L/minute per square meter Amines were tapered off in steps of 0.02 and μg/kg ... for determination of coagulation-fibrinolysis parameters and interpretation JMB and BM, was responsible for determination of IL-6 and interpretation RM was the surgical team and was responsible...

Ngày tải lên: 10/08/2014, 09:22

... understanding of the study or treatment procedures, although a high proportion of parents showed no understanding of the risks and of the research nature of the clinical trials Randomization, ... feasibility of providing information about clinical trials according to informed consent criteria and the understanding of information related to clinical trials The appreciation of children and adolescents ... objective of the trial were not well understood and appreciation was low – by both children and adolescents and often by parents The capacity to understand the nature of placebo was low and children and...

Ngày tải lên: 13/08/2014, 18:21

... 60°C for 10 hours, and nanofiltration Protein C; antithrombin, heparin and albumin added Cofact Sanquin, the Netherlands 56-140 28-80 100 56-140 Solvent/detergent and 15 nm nanofiltration Antithrombin ... Octapharma, Austria and France Profilnine SD Viral inactivation Additional information Brand name 148 40 100 160 Solvent/detergent Heparin added 44-152 36-96 100 50 Solvent/detergent and nanofiltration ... Care 2011, 15:409 http://ccforum.com/content/15/2/409 Page of Table Composition of PCCs in the World Federation of Hemophilia register of clotting factor concentrates International units relative...

Ngày tải lên: 14/08/2014, 07:21

... Hematological and biochemical evaluations For assessment of safety of 5-Loxin® and Aflaseveral parameters were evaluated in serum, urine and whole blood of all subjects at each visit of the study ... comparative efficacy and tolerability of 5-Loxin® and Aflapin® in the treatment of OA of the knee Materials and Methods Study materials BE-30 (5-Loxin) is a novel Boswellia serrata extract standardized ... software to evaluate the efficacy of 5-Loxin® and Aflapin® in comparison with the placebo group in terms of improvement in pain and physical function scores at baseline and on days 7, 30, 60 and...

Ngày tải lên: 25/10/2012, 11:40

... journal of the American Association for the Study of Liver Diseases (AASLD), and of Current Hepatitis Reports, and a member of the Editorial Board of the Journal of Hepatology and of the Journal of ... Professor of Medicine at the University of Paris XII and the Director of the Department of Virology, of INSERM Unit U635 and of the French National Reference Center on Viral Hepatitis B, C and ... genotypes and (B), and genotypes 4, and (C) Int J Med Sci 2006, HCV genotypes and Patients infected with HCV genotypes or have a 70%-80% likelihood of an SVR with a low dose of ribavirin and only...

Ngày tải lên: 02/11/2012, 09:56

... difficulties of managing hepatitis B infection Hence, further research and understanding in this sector may bring exciting new information and better understanding of the natural history of HBV and supplement ... incidence of hepatic decompensation was 16%, the incidence per 100 person years was 3.3 and the mean interval between the time of diagnosis of cirrhosis and the onset of first episode of decompensation ... activity, and with or without HBeAg seroreversion Clinical Spectrum of HBV Infection Primary Infection –Subclinical Infection and Acute hepatitis B Majority of HBV infection in children are subclinical...

Ngày tải lên: 02/11/2012, 11:17

Ngày tải lên: 03/11/2012, 11:11