... (percentage of CD19 + cells) Results Clinical characteristics of the patients and response to rituximab therapy The clinical and laboratory characteristics of the RA patients who were treated with rituximab ... Teng and colleagues found that only 32% of RA patients had complete depletion of CD19+ cells within the BM as compared with 100% in the PB [4] Leandro and colleagues reported a variable degree of ... in the PB and in the BM of RA patients (d) Representative flow cytometry histograms of HLA-DR expression in PB and BM CD19+-gated cells of a RA patient at baseline and after treatment with rituximab...
Ngày tải lên: 09/08/2014, 14:22
... schizophrenics) and 67–75% among outpatients, with 45 and 28% of combination therapies in in- and outpatients being reported, respectively [28-30] The rates of prescription of conventional and atypical ... report [4], with non-FPA patients, no significant differences are observed: benzodiazepines (69% of FPA patients; 69% of non-FPA patients) , atypical (in 51 and 53% of patients respectively) and conventional ... at the subjective wellbeing (SWN) scale and number (%) of patients with positive DAI-30 score at admission to and discharge from SPDC, in patients treated with antipsychotics (atypical, conventional...
Ngày tải lên: 08/08/2014, 23:20
Báo cáo y học: " Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study" potx
... loss in RA patients A longitudinal study of the impact of smoking intensity (and cessation) on the body composition of patients with RA may throw more light on the mechanistic basis of these observations ... current and ex-smoker pack-groups However, an ANCOVA model with gender and pack-group as factors and age and weight as covariates (following stepwise elimination of ESR, CRP, DAS28, HAQ score, and ... inception and development of protocol and in the review of the manuscript and served as PhD program supervisor MK provided advice on protocol development and body composition assessments and participated...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "The accuracy of echocardiography versus surgical and pathological classification of patients with ruptured mitral chordae tendineae: a large study in a Chinese cardiovascular center" ppt
... compare the accuracy of the preoperative predictive tests of thoracic echocardiography (TTE) and transesophageal echocardiography (TEE) with the gold standards of surgical findings and pathological ... All patients underwent standard two-dimensional and Doppler echocardiographic examinations with detailed evaluation of heart function Imaging planes were standardized, and they included the parasternal ... mild (n = 25), Table Surgical types of RMCT and relationship between surgical methods and location and degree of RMCT operation methods degree of RMCT# location of RMCT* Anterior Posterior both...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo khoa hoc:" Neurohumoral, immunoinflammatory and cardiovascular profile of patients with severe tetanus: a prospective study" docx
... enrolment A portion of this population was part of the entire cohort of our previous study reporting demographics and prognosis of patients with tetanus [2] The main variables of the study were: ... complications and electrocardiogram (EKG) Evaluation of autonomic profile, catecholamine levels and TNF-α Autonomic instability was characterized by the presence of blood pressure and heart rate ... system function with spectral analyses of heart rate variability in a case of tetanus, recently revealed profoundly decreased activity of both sympathetic and parasympathetic modulation of cardiac...
Ngày tải lên: 11/08/2014, 08:20
Báo cáo y học: " Pro/con clinical debate: The use of prone positioning in the management of patients with acute respiratory distress syndrome" potx
... 0–31 Quartiles of SAPS II Proning may benefit the most seriously ill subset of patients with acute respiratory distress syndrome Those in the quartile with the highest Simplified Acute Physiology ... Kastani D: Effect of the prone position on patients with hydrostatic pulmonary edema compared with patients with acute respiratory distress syndrome and pulmonary fibrosis Am J Respir Crit Care ... Effect of prone positioning on the survival of patients with acute respiratory failure N Engl J Med 2001, 345:568-573 The ARDS Network: Ventilation with lower tidal volumes as compared with traditional...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Effect of the molecular adsorbent recirculating system and Prometheus devices on systemic haemodynamics and vasoactive agents in patients with acute-on-chronic alcoholic liver failure" potx
... disease), and if there was clinical or microbiological evidence (culture of urine, blood, sputum and ascites) indicative of ongoing infection For the purpose of this study, patients with hepatorenal ... Systemic and regional hemodynamics in patients with liver cirrhosis and ascites with and without functional renal failure Gastroenterology 1989, 97:1304-1312 Wiest R, Groszmann RJ: The paradox of nitric ... ± standard error of the mean, and as ∆change ± standard error of the mean The paired t test was used for pairwise comparison within groups, or the Wilcoxon test when appropriate Analysis of variance...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: " Effect of oral beta-blocker on short and longterm mortality in patients with acute respiratory failure: results from the BASEL II-ICU study" ppt
... with or without treatment with beta-blocker at admission in patients with cardiac aetiology of respiratory failure (adjudicated final diagnosis of heart failure; P = 0.008) and patients with non-cardiac ... Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed ... one-third of ICU patients is multi-causal [15] Accordingly, the aim of the present study was to assess in-hospital and one-year mortality in a cohort of consecutive ICU patients with acute respiratory...
Ngày tải lên: 13/08/2014, 21:21
báo cáo hóa học:" The integrated care pathway reduced the number of hospital days by half: a prospective comparative study of patients with acute hip fracture" doc
... discussed with the patients' and their relatives in order to obtain a spirit of understanding The nurses collaborated with the patients and their families throughout the hospital stay and were ... research [17] The aim of the present study was to evaluate the effectiveness of an ICP in patients with an acute fracture of the hip The main outcome measure was the length of hospital stay; secondary ... continuity and an accelerated training programme without disturbing the flow of patients with other diagnoses ICP documentation was developed in the form of a check list that displayed what to and when...
Ngày tải lên: 20/06/2014, 00:20
Báo cáo hóa học: " Albuterol enantiomer levels, lung function and QTc interval in patients with acute severe asthma and COPD in the emergency department" pptx
... effects of high levels of (S)-albuterol remain unclear [19,22] Most of the pharmacokinetic and pharmacodynamic studies of albuterol have been performed on healthy, mildly asthmatic patients, within ... in acute severe asthma patients, with an up to fivefold difference in concentrations of (R)- and (S)-albuterol [30] The objective of this study was to observe the relationship between (R)- and ... presented to the DEM with an acute exacerbation of asthma The inclusion criteria were adult patients, aged between 18 and 65 years, and self-reported rac-albuterol utilisation within 24 h prior...
Ngày tải lên: 21/06/2014, 03:20
Báo cáo hóa học: " FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study" potx
... 1:21 http://www.annalsofintensivecare.com/content/1/1/21 Page of Table Baseline characteristics of patients with and without acute kidney injury No acute kidney injury Number Acute kidney injury ... impact of AKI on levels of FGF23 and that was in the setting of rhabdomyolysis [40] We sought to determine the impact of AKI on FGF-23 and parathyroid hormone (PTH) levels in patients with AKI ... increased risk of death As expected, AKI patients had, on average, higher concentrations of serum phosphorous compared with patients without AKI In addition, a larger proportion of AKI patients had...
Ngày tải lên: 21/06/2014, 03:20
Báo cáo khoa học: " Protective ventilation of patients with acute respiratory distress syndrome" doc
... Santos and Slutsky that this is associated with apoptosis of cells in distal organs (kidney, villi of colon) and end-organ dysfunction (kidney), which potentially underlies the development of MOF ... bronchoalveolar lavage fluid [7], and was associated with a lower incidence of MOF [8] However, the measurement of proinflammatory cytokines does not address the issue of maintenance of alveolar–epithelial ... tissue and bronchoalveolar lavage levels of proinflammatory cytokines, and that stabilization of alveoli is a key issue in reducing atelectrauma The debate on how to best manage patients with ARDS...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo y học: " Pro/Con Debate: Does recombinant factor VIIa have a role to play in the treatment of patients with acute nontraumatic hemorrhage" ppt
... multicenter survey of off-label use of rFVIIa in American academic hospitals [16], which reported that only 52% of the patients stopped bleeding within hours of rFVIIa administration and 9% suffered ... bleeding, even off-label use demands reasonable expectation of benefit Ongoing bleeding and reasonable expectation of benefit are mandatory even for compassionate off-label use of rFVIIa Competing ... contradicted many initial expectations and demonstrated no clinical benefit of rFVIIa In 2004 RomeroCastro and coworkers [15] reported that all 10 patients with cirrhosis and bleeding varices stopped bleeding...
Ngày tải lên: 12/08/2014, 23:24
Báo cáo y học: "Midregional pro-Adrenomedullin in addition to b-type natriuretic peptides in the risk stratification of patients with acute dyspnea: an observational study" ppt
... interpretation of data, and critical revision of the manuscript for important intellectual content NGM, AB, and HF participated in analysis and interpretation of data, and critical revision of the Page of ... principles of the Declaration of Helsinki and approved by the local ethics committee Written informed consent was obtained from all participating patients Clinical evaluation and follow-up Patients ... identification of patients at highest risk for adverse outcomes with acute dyspnea remains a challenge Patient history and physical examination remain the cornerstone of clinical evaluation [3],...
Ngày tải lên: 13/08/2014, 18:22
Báo cáo y học: "Acidemia does not affect outcomes of patients with acute cardiogenic pulmonary edema treated with continuous positive airway pressure" pps
... episode of ACPE The etiology of hypoventilation as a sign of pump failure is twofold On the one hand, such as among patients with acute exacerbation of chronic bronchitis, hypercapnia, often acute ... and those with a normal pH (controls) Among patients of the acidotic group, three subgroups were identified according to PaCO2 and HCO3- values: patients with respiratory acidosis, patients with ... according to the type of acidemia on admission A total of 12 patients (10%) with respiratory acidosis, 11 patients (13%) with metabolic acidosis, four patients (6.2%) with mixed acidosis and eight controls...
Ngày tải lên: 13/08/2014, 21:21
Báo cáo y học: "Copeptin and risk stratification in patients with acute dyspnea" ppsx
... NTproBNP and outcome was observed Those patients with low rates of Copeptin had low rates of death, irrespective of NT-proBNP levels at 30 days In those patients with an elevation of both, Copeptin and ... consisted of unselected patients presenting to the emergency department of the University Hospital of Basel, Switzerland, with a chief complaint of acute dyspnea From April 2006 to March 2007, 292 patients ... analysis and interpretation of data and critical revision of the manuscript for important intellectual content NM and AB participated in analysis and interpretation of data and critical revision of...
Ngày tải lên: 14/08/2014, 07:21
Báo cáo hóa học: " Vaccination with a plasmid DNA encoding HER-2/ neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial" pptx
... and handling the patient samples after HN had departed from CCK and co-ordinating the collaboration with KLK’s laboratory Together with EL she also summarized and processed the patient data and ... al.: Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial Journal of Translational ... after three cycles of Her2-pDNA plus GM-CSF and IL-2 Evaluation of Her2-specific antibody responses Pre- and post-vaccination sera from all patients were analyzed for the presence of anti-Her2 antibodies...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" Mapping of the EQ-5D index from clinical outcome measures and demographic variables in patients with coronary heart disease" pptx
... available and the models should only be used for patients with similar clinical and demographic profiles Future work should include validating the model on an independent sample [13], and for patients ... stages of disease Further details of the studies used, the clinical measures, the use of measurements from different time points, and the individual relationship between each of these clinical ... people with quite a wide range of problems in a given domain, corresponding to widely different levels of HRQoL A 5-level version of the EQ-5D has been created and piloted and shows evidence of feasibility...
Ngày tải lên: 20/06/2014, 16:20
Báo cáo khoa học: "Evaluation of clinical, laboratory and morphologic prognostic factors in colon cancer" ppsx
... that radical resection and type of operation are important prognostic factors In a recent Table 2: Results of multivariate analysis of clinical and laboratory data of patients with colon cancer Source ... http://www.wjso.com/content/6/1/98 of patients with colon cancer, considering survival and pT staging as the independent variables Materials and methods Patients A total of 103 patients with colon cancer, who ... hepatic flexure of patients (8.7%), in splenic flexure of patients (7.6%), in descending colon of 10 patients (10.9%) and in sigmoid colon of 34 patients (36,9%) Operative procedure All patients were...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo y học: "Ultrasonography, magnetic resonance imaging, radiography, and clinical assessment of inflammatory and destructive changes in fingers and toes of patients with psoriatic arthritis" pot
... patients with PsA by comparison with MRI, x-ray, and clinical findings Materials and methods Patients Fifteen patients with PsA, with RA, and healthy control persons (CTRLs) were examined with US, ... performed with a ST that was half of the acquired ST Projection radiography X-ray of hands and feet in a posterior-anterior projection was performed within a month of the US X-rays of both hands and ... ultrasonography, x-ray, and clinical examination, with MRI as standard reference method Sensitivities and specificities of US, x-ray, and clinical examination, with MRI as the standard reference method,...
Ngày tải lên: 09/08/2014, 10:21