... verified independently by reamplifying the corresponding fragment and repeating the sequencing procedure using both forward and reverse primers in the samples fixed in Bouin's solution Regarding the ... 15 ppm in screw cutting industry during c.332 G>A 58 years women no c.463+1 G>C 42 years man no Other occupational exposures identified cutting oils asbestos cutting oils in screw cutting industry ... digested during 18 hours at 56°C with proteinase K to obtain complete digestion Second, paraffin was not removed by xylene extraction: we used instead the fact that the paraffin wax melts during the...
Ngày tải lên: 20/06/2014, 00:20
... impaired in group that comprised patients with systolic dysfunction Also, the peak VO2 was significantly decreased in group patients with systolic dysfunction, in comparison with that in patients without ... distensibility is not impaired in patients with different forms of Chagas' disease, even in those with heart failure Our results observed in patients without CHF coincide with those observed by Consolim-Colombo ... more intense in patients with severe CHF, patients who were excluded in our study so as not to interfere in a possible effect of Chagas' disease on the PWV Thus, as we excluded patients with severe...
Ngày tải lên: 11/08/2014, 08:20
Báo cáo y học: "Hypoalbuminaemia – A Marker of Cardiovascular Disease in Patients with Chronic Kidney Disease Stages II - IV"
... like chronic inflammation and malnutrition as predictors of the CVD in chronic kidney disease This multifactorial disease introduces new challenges in predicting and treating patients early in ... and mortality in CKD 3-5 patients in Spain (31) Our study extends this finding to patients with more preserved renal function in American population Our hypothesis that serum albumin is a significant ... electrocardiogram in the prediction of cardiac death in dialysis patients Arch Intern Med 1988; 148: 2381-2385 20 Aronow Ws Usefulness of serum creatinine as a marker for coronary events in elderly patients with...
Ngày tải lên: 03/11/2012, 11:52
báo cáo hóa học: " The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease" pot
... range commonly encountered in patients with chronic disease. [26,27] A change of 1.5 points corresponds approximately to a 20% change from these baseline scores In patients with substantially lower ... anxiety in diseases such as COPD evidence is still lacking to provide strong recommendations However, the treatment of depression in disease such as COPD will be increasingly important In trials using ... with other diseases Patients included in our study might, however, represent patients with advanced chronic disease because mean HADS anxiety (7.03) and depression scores (7.63) were in the range...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " What determines subjective health status in patients with chronic obstructive pulmonary disease: importance of symptoms in subjective health status of COPD patients" pdf
... 100, the lower scores indicating better health status [19-21] The SGRQ has been translated into different languages and used in several studies of COPD patients, including in Norway [22,23] The ... the learning and coping centre at Haugesund Hospital for assisting the recruitment of COPD patients References 10 11 Competing interests The authors declare that they have no competing interests ... Sokolov I: Accuracy of nine commercially available pulse oximeters in monitoring patients with chronic respiratory insufficiency Monaldi Arch Chest Dis 1994, 49:348-353 Bausewein C, Farquhar M, Booth...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Physician-estimated disease severity in patients with chronic heart or lung disease: a cross-sectional analysis" ppt
... primary care patients with chronic heart or lung disease provided an excellent venue for examining a single-item physician-rated global estimate of disease severity Several important findings emerged ... terminally ill cancer patients [14-19] One study found that physician estimates had an independent effect beyond models incorporating other risk factors in predicting survival in patients with ... infarction was the single strongest predictor of the patient actually having an infarction [37] Other investigators found that in predicting return to work in patients with coronary disease, both physicians'...
Ngày tải lên: 20/06/2014, 15:20
Báo cáo y học: "A comparative study of anxiety and depression in patients with bronchial asthma, chronic obstructive pulmonary disease and tuberculosis in a general hospital of chest diseases" ppsx
... studies performed with patients with respiratory failure, with depression being observed in 30% of patients with moderate failure and in 50% in patients with severe obstructive pulmonary disease [15,16] ... suffocating disease status may explain the high percentage of depression in patients with COPD and BA in the study, which was higher than the percentage reported in studies performed with in- patients ... and nursing personnel The observed higher prevalence of depression and anxiety in patients with chronic pulmonary disease – compared to other chronic diseases – may be explained within this context...
Ngày tải lên: 08/08/2014, 23:20
Báo cáo y học: "Positive anti-citrullinated protein antibody status and small joint arthritis are consistent predictors of chronic disease in patients with very early arthritis: results from the NOR-VEAC cohort" pot
... joint, proximal interphalangeal joint, or metatarso-phalangeal joint joint swelling ACPA = anti-citrullinated protein antibody; CI = confidence interval; CRP = C-reactive protein; DMARD = disease- modifying ... Metacarpo-phalangeal joint, proximal interphalangeal joint, or metatarso-phalangeal joint joint swelling.*P < 0.25, variable selected for inclusion in multivariate analyses ACPA = anti-citrullinated protein antibody; ... patients with missing data: SJC/TJC 0, CRP 0, ESR 2, HAQ 9, CCP 42, IgM RF 51, smoking 3, morning stiffness 9, small joints ACPA = anti-citrullinated protein antibody; CRP = C-reactive protein;...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study" pdf
... [15]) and occur in both patients with LN and patients with lupus but not nephritis In one study, positivity for anti-α-actinin distinguished patients with nephritis from those without nephritis ... patients with SLE Improved monitoring of renal disease in patients with LN is more likely to be achieved by combining anti-dsDNA tests with assays more specific for renal dysfunction, such as urinary ... albumin of at least 30 g/L, and either normal serum creatinine if the baseline creatinine was less than 260 μmol/L or a 50% decrease in creatinine if the baseline value was at least 260 μmol/L Patients...
Ngày tải lên: 09/08/2014, 14:22
báo cáo khoa học: "The importance of organizational characteristics for improving outcomes in patients with chronic disease: a systematic review of congestive heart failure" pdf
... approach disseminating research findings into routine care The CAS framework suggests that local contexts and local interactions between individuals are critical considerations in designing interventions, ... review of interventions to improve outcomes for patients with Type diabetes, expanding the data regarding the importance of considering health care settings as CAS beyond a single chronic disease ... pattern of interactions, including non-verbal communication, among agents • Introducing new agents into the system • Letters to patients • Nurse-led heart failure group clinic • Clinical reminders...
Ngày tải lên: 10/08/2014, 10:23
báo cáo khoa học:" Validation of the "World Health Organization Disability Assessment Schedule, WHODAS-2" in patients with chronic diseases" ppt
... all subjects In addition, patients were clinically evaluated with disease- specific severity scales, and with standardised instruments measuring disability and quality of life Sample Patients had ... contains 36 items on functioning and disability with a recall period of 30 days[8] covering domains: Understanding and Communicating (6 items), Getting around (5 items), Self-care (4 items), Getting ... each domain by adding the item responses (the score computation allows for up to 30% of missing items per domain) and transforming them into a range from to 100, with higher scores indicating higher...
Ngày tải lên: 12/08/2014, 01:21
báo cáo khoa học:" General and disease-specific quality of life in patients with chronic suppurative otitis media a prospective study" pot
... months This definition covers adequately the clinical course and findings in our patients from a clinical point of view The following two main types of CSOM were differentiated: chronic suppurative ... use in clinical studies Therefore, inclusion in the study was determined according to Nadol [1]: disease of the middle ear and/or mastoid with irreversible mucosal damage or infection lasting ... before starting data collection Patients were included in the study from April 2006 through July 2007 Data collection was completed in July, 2008 Patients In this study, patients with chronic suppurative...
Ngày tải lên: 12/08/2014, 01:22
Báo cáo y học: "The effects of long-acting bronchodilators on total mortality in patients with stable chronic obstructive pulmonary disease" pdf
... associated with tiotropium use in patients with chronic obstructive pulmonary disease Arch Intern Med 2009, 169(15):1403-1410 Soriano JB, Kiri VA, Pride NB, Vestbo J: Inhaled corticosteroids with/ without ... intensifies with disease progression and during clinical exacerbations [23,24] Once COPD develops, the inflammatory response continues to persist many years after smoking cessation [25] Although the inflammatory ... were obtained using these search terms on their own and in combination Abbreviations BUD/F: budesonide/formoterol combination; CI: confidence interval; COPD: chronic obstructive pulmonary disease; ...
Ngày tải lên: 12/08/2014, 11:21
Báo cáo y học: "Alterations in the muscle-to-capillary interface in patients with different degrees of chronic obstructive pulmonary disease" pps
... altered in COPD patients [8,9,13] This finding can be explained by a reduction in fibre area as previously shown in COPD patients [10] This is also in line with a previous study [9] indicating a ... muscle of patients with COPD [10] This is in line with previous studies [3,7-9] and together with previous findings of a decrease in oxidative enzyme activities in COPD [6,7] our findings indicate ... to our findings may be a reduced mitochondrial volume of the muscle fibre This explanation would be in line with a recent study showing a decrease in mitochondrial volume in patients with COPD...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: " CD8 positive T cells express IL-17 in patients with chronic obstructive pulmonary disease" ppsx
... polymorphism and chronic inflammatory lung diseases, including bronchial asthma and COPD, suggesting that IL-17F may be critically involved in the pathogenesis of chronic inflammatory lung diseases [15] ... supporting the potential involvement of IL-17A in the phenotypic manifestations of COPD In addition, transgenic over expression of Il-17 in the alveoli of murine lung induces lung inflammation with ... and visualized with DAB/hydrogen peroxide After counterstaining with haematoxyline, sections were dehydrated in increasing ethanol gradient and 100% xylene immediately before performing LCM The...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: " Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using modelbased approaches" ppt
... three anticholinergic agents and fenoterol using a metered dose inhaler in patients with chronic obstructive pulmonary disease Thorax 1995, 50:62-66 Littner MR, Ilowite JS, Tashkin DP, Friedman ... arm of each study, for both indacaterol (lefthand panel) and comparators (right-hand panel) Visual inspection of the indacaterol data points indicated that with increasing dose the response asymptotically ... response changed with baseline FEV As baseline FEV increased, both the steepness and the maximum of the dose response increased In particular, the lowest quartile, with a baseline FEV of less...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: " Vascular endothelial growth factor: an angiogenic factor reflecting airway inflammation in healthy smokers and in patients with bronchitis type of chronic obstructive pulmonary disease?" ppsx
... were demonstrated in ex-smoking patients with COPD in comparison with ex-smoking healthy control subjects Furthermore, in COPD patients, increased numbers of macrophages with increased KDR/Flk-1 ... smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers Respir Res 2005, 6:38 Keatings VM, Collins PD, Scott DM, Barnes PJ: Differences in interleukin-8 ... study examining the correlation of VEGF with pulmonary function and inflammatory mediators in current smokers with mild COPD and intact alveolar structure If our study included COPD patients with...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: " Improved outcomes in patients with chronic obstructive pulmonary disease treated with salmeterol compared with placebo/usual therapy: results of a meta-analysis" ppsx
... contributions 15 RS was involved in the concept and planning of the meta analysis and in writing and editing the manuscript; PW and MW were involved in the writing and editing of the manuscript ... from the earliest assessment point (3 months) and maintained at months and 12 months, indicating that there was no decline in efficacy over this period There is increasing recognition that patient-centred ... 349:1498-1504 CPMP/EWA/562/98: Points to consider on clinical investigation of medicinal products in the treatment of patients with chronic obstructive pulmonary disease (COPD) 1999 21 22 23 24...
Ngày tải lên: 12/08/2014, 16:20
Báo cáo y học: "Evaluation of an ambulatory system for the quantification of cough frequency in patients with chronic obstructive pulmonary disease" ppsx
... Effects of abdominal and thoracic breathing on breathing pattern components in normal subjects and in patients with chronic obstructive pulmonary disease American Review of Respiratory Disease 1984, ... recording is 1-min and 1-sec from the physiologic recordings LS data were visually inspected by two independent reviewers who remained blinded to the video data Each noted the time (hour, minute ... represented in the study, which was due to an inauspicious baseline imbalance Third, the data were collected in a clinical setting due to the requirement for video monitoring equipment However, patients...
Ngày tải lên: 13/08/2014, 08:20
Báo cáo y học: "A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease" ppt
... assess the inter-laboratory variability of FibroTest and ActiTest, including their six serum liver components, in patients with chronic liver disease, and to identify factors associated with that ... error over the investigated range As previously observed, when ordinary linear regression (in combination with correlation analysis in the Passing Bablock method) gave poor estimates, in particular ... fibrogenic events occurring within the liver Furthermore, and because treatment is now so effective in patients with genotype or infection, the utility of biopsy in this setting could be challenged...
Ngày tải lên: 13/08/2014, 13:20