chemotherapy of infectious and neoplastic diseases

... 30 Male and Female Hormones, 435 Androgens, 435 Source and Regulation of Androgen Synthesis, 435 Physiologic Effects of Androgens, 437 Pharmacologic Use of Androgens, 437 Clinical Use of Androgens, ... Adverse Effects of Clinical Androgen Use, 439 Antiandrogens, 440 Androgen Abuse, 440 Nature of Androgen Abuse, 440 Effects of Androgens on Athletic Performance, 442 Adverse Effects of Androgen Abuse, ... Assistant Professor Department of Physical Therapy and Rehabilitation Science University of Maryland School of Medicine Baltimore, Maryland Steven Raymond Tippett, PT, PhD, SCS, ATC Associate Professor...

Ngày tải lên: 29/03/2014, 13:20

... Toronto, Ontario, Canada ALEXANDER I TRÖSTER, PhD • Department of Psychiatry and Behavioral Sciences and Department of Neurological Surgery, University of Washington School of Medicine, Seattle, WA ... principally on the head of dendritic spines of projection neurons and less frequently with dendritic shafts of projection neurons and interneurons (18) The density of cortical innervation of striatal interneurons ... summarize some of these data and discuss their relevance for basal ganglia pathophysiology 3.2 Collateralization of Striatofugal Neurons and Co-localization of Dopamine Receptors One of the important...

Ngày tải lên: 05/03/2014, 23:20

... diagnosis and management of tuberculosis and HIV, and completion of study documents Supplies and equipment necessary for the implementation of the revised guidelines will be installed and relevant ... Journal of Infectious Diseases, 2001, 5:6369 21 Luzze H et al Evaluation of suspected tuberculous pleurisy: clinical and diagnostic findings in HIV-1-positive and HIV-negative adults in Uganda International ... by members of the Core Group of the global TB/ HIV Working Group of the Stop TB Partnership and the Strategic and Technical Advisory Group for Tuberculosis (STAG-TB) and the Strategic and Technical...

Ngày tải lên: 15/03/2014, 03:20

... significantly and she was transferred to the high dependency unit (HDU) with septicaemic shock with a pulse rate of 110/min, blood pressure of 70/43 mmHg, and an oxygen saturation of 94% on litres/min of ... pelvis and biopsy of the symphysis pubis highlighted the presence of osteomyelitis of the pubic bone, suggesting the possibility of it being a cause rather than a complication or an association of ... pelvis andsymphsis (white arrows) T1-weighted MRI of the vagina, (sagittal view)extending into T1-weighted MRI of the pelvis (sagittal view) exhibiting gross oedema of the urethra, vagina, and rectum...

Ngày tải lên: 09/08/2014, 07:21

... received cycles of FCR: fludarabine at a dose of 25 mg/m2 i.v on days to 3; cyclophosphamide at a dose of gr/m2 i.v on day and rituximab Page of at a dose of 375 mg/m2 was given on day of each cycle ... agents and purine nucleoside analogs Czuczman et al reported an incidence of t-MDS and t-AML (treatment-related acute myeloid leukemia) after 90 Y-RIT of 0.3% per year after the diagnosis of NHL and ... population composed mainly of patients with a history of prior treatment using rituximab plus chemotherapy A longer follow up and a larger number of patients with relapsed grades and FL are required...

Ngày tải lên: 10/08/2014, 10:21

... Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics Prepared by Lynne M Mofenson, MD1 Michael ... 16% of children dying with HIV/AIDS during 1992 and 1993 (412), in 29% of those dying during 1997 and 2000 (413), and in 44% of those dying during 2000 and 2001 (414) The mode of transmission of ... group of adult HIV and infectious disease specialists Both sets of guidelines were prepared by the Opportunistic Infections Working Group under the auspices of the Office of AIDS Research (OAR) of...

Ngày tải lên: 12/02/2014, 12:20

... Active against Candida, Aspergillus species and some of the rarer molds trough of > 0.25 mcg/mL after d of therapy) · Active against dimorphic fungi and C neoformans · Active against Candida, Aspergillus ... safety profile · Primary therapy for candidemia and invasive candidiasis (category 1) · Similar efficacy compared to caspofungin and compared to L-AMB 10 as primary therapy for candidemia and invasive ... species and some of the rarer molds · Active against dimorphic fungi and C neoformans · Standard of care as primary therapy for invasive aspergillosis (category 1) 1,3 · Effective in candidemia...

Ngày tải lên: 14/02/2014, 22:20

... monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases ... diagnosis and management of skin and soft-tissue infections Clin Infect Dis 2005;41(10):1373–406 May AK, et al Treatment of Complicaed Skin and Soft Tissue Infections Surg Infect 2009;10(5):467–99 Anderson ... of Health-Systems Pharmacists (ASHP), Infectious Diseases Society of America (IDSA), and Society of Infectious D­seases Pharmacists (SIDP) i suggest the use of al­ernative agents active against...

Ngày tải lên: 22/03/2014, 14:20

... potency and cost Peptide-based drug candidates are limited by insufficient efficacy and unfavorable pharmacokinetics MAbs have increasingly gained favor in large part because of the development of ... to reduce the rate of hospitalization of at-risk infants by about 55% in clinical studies and now serves as the primary medical means of RSV prevention [11-13] Prevention of Human Rhinovirus ... Targeting viral mRNA is one of the most active areas of research and development Several strategies have emerged over the years and are being tested pre-clinically and clinically They include:...

Ngày tải lên: 18/06/2014, 22:20

... potency and cost Peptide-based drug candidates are limited by insufficient efficacy and unfavorable pharmacokinetics MAbs have increasingly gained favor in large part because of the development of ... to reduce the rate of hospitalization of at-risk infants by about 55% in clinical studies and now serves as the primary medical means of RSV prevention [11-13] Prevention of Human Rhinovirus ... Targeting viral mRNA is one of the most active areas of research and development Several strategies have emerged over the years and are being tested pre-clinically and clinically They include:...

Ngày tải lên: 20/06/2014, 04:20

... distribution of condoms, peer education and screening of STD and reproductive tract infections The aims of program is to prevent and reduce HIV and LRTI with effectiveness and low cost 1.3.3 Program of ... guidlines of WHO and the Central Hospital of Dermatology 2.2.5 Content and intervention process Examination, treatment for FSWs and monitoring of clinical and laborator expressions Communication and ... knowledge and skills for them to improve the quality and efficiency of detection and the treatment of genital infections Have to continue monitoring of interventions for female sex workers and the...

Ngày tải lên: 25/07/2014, 13:32

... 13, 30, 50, and 70 keV/μm), B) X-rays and neon-ions (LET 13, 70, and 120 keV/μm), C) X-rays and silicon-ions (LET 55, 150, and 250 keV/μm), and D) X-rays, argon-ions (LET 100 keV/ μm), and iron-ions ... quadratic model by PRISM5 software on MacOSX10.6 Error bars indicate standard error of the means Results Cellular doubling time, chromosome number, and p53 status of U-CH1-N The original U-CH1 ... Cycle Distribution and DNA Content Both cell cycle distribution and DNA profile were measured by a flow cytometer The results are summarized in Table DNA profile showed that U-CH1-N and HeLa were...

Ngày tải lên: 09/08/2014, 09:21

... Social phobia and disruptive social anxiety are features of the lives of many thousands of people But exactly what is social phobia? What causes it? What is its nature and what kinds of treatments ... key concepts and methods and a substantive body of research, this book aims to answer these questions and clarify social phobia by means of critical discussions and examination of evidence It ... clinicians, and students in clinical and health psychology and psychiatry AR I E L ST R AV Y N S K I is Professor of Clinical Psychology in the Department of Psychology at the University of Montreal...

Ngày tải lên: 21/09/2012, 10:54

... signs and symptoms of medical illness and facilitating referral for appropriate evaluation and intervention Psychiatrists must also be aware of the medical risks of psychotropic medications and ... phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of exposure The frequency of the syndrome ... significant loss of weight gained while taking atypical antipsychotics, and the modifications of eating and exercise habits help patients maintain the weight loss [12] Pharmacologic treatment of obesity...

Ngày tải lên: 25/10/2012, 10:51

... indication of techniques for the treatment of this kind of surgical complication Spontaneous healing of to mm openings can occur, while untreated larger defects are connected with the pathogenesis of ... characteristics of OAC/OAF; the apexes of tooth 26 were in extremely close approximation to the maxillary sinus, and an area of periapical rarefaction was evident (Fig 1) After the failure of the endodontic ... sinus over the involved tooth and the localized swelling and thickening of the sinus mucosa; only close the root of 2.7 a periapical lesion was present; radiopacity of different degrees was evident...

Ngày tải lên: 25/10/2012, 11:48

... common form of arthritis, and it is often associated with significant disability and an impaired quality of life Clinical and radiographic surveys have found that the prevalence of OA increases ... medication (narcotics, oral NSAIDs, topical NSAIDs) within four weeks of randomization Use of acetaminophen or ibuprofen within days of randomization Subject is unwilling to stop taking pain medication ... Canada) Appropriateness of Measurements The efficacy and safety assessments used in this study were standard for OA and are widely used and recognized as reliable, accurate, and relevant WOMAC scores...

Ngày tải lên: 26/10/2012, 09:48

... into the cement and therefore, the total dose of antibiotics should not exceed 10% of the weight of the cement in order to avoid fracture of the cement spacer [27] The implantation of an ALC spacer ... time of reimplantation and allow delivery of the antibiotics of choice according to sensitivities [23,36] The disadvantage of a static spacer is that it does not allow physiological motion of the ... A sufficient degree of antibiotic elution from PROSTALAC has been measured for a period of over months when at least 3.6 g of tobramycin per 40 gram of bone cement and gram of vancomycin are used...

Ngày tải lên: 26/10/2012, 09:53

... of soft-tissue shortening and provision of sufficient infection therapy is the usage of temporary, antibiotic-loaded cement spacers [5, 7, 14, 24] Although their indication in the treatment of ... evaluated scores of the patients were compared to ones of a control group of similar age and gender, representative of the german population Statistics: Due to the small sample size and the non-symmetrical ... resected under consideration of the later implantation of the prosthesis into the proximal femur Tissue samples (bone- and soft tissue) were sent for bacteriological and histological examination...

Ngày tải lên: 26/10/2012, 09:53

... notice a rate of 1/10 and 3/13 dislocations after implantation of a standardized hip spacer, respectively On the other hand, Ries and Jergesen [26], Koo et al [16], Shin et al [30] and Takahira ... art of the spacer’s production as well as the fixation method Leunig et al [18] reported dislocations of the hip in of 12 patients after use of hand-formed spacers, whereas Magnan et al [19] and ... and incompliance of the patient with regard to partial weight bearing A review of the literature about hip spacers showed a tendency that hand-made spacers might dislocate more often than standardized-made...

Ngày tải lên: 26/10/2012, 09:53