... testing and adjuvant chemotherapy for breast cancer patients in New Hampshire Methods: We examined New Hampshire State Cancer Registry data on 5630 female breast cancer patients diagnosed from ... Receiving chemotherapy Receipt of chemotherapy was documented in 2264 (40.2%) patients in the breast cancer cohort, and 336 (22.2%) of patients who received ODX Receipt of chemotherapy among patients ... the adjusted model (Table S2) Chemotherapy recommendation Chemotherapy was recommended for 2701 (48.0%) patients in the breast cancer cohort and 459 (30.4%) of patients who received ODX In the
Ngày tải lên: 28/09/2020, 09:41
... with Breast Cancer who had Received Chemotherapy 120 5.3 The Support Systems that Influenced Resilience among Breast Cancer Survivors 125 5.4 Adaptation to Breast Cancer Diagnosis and Chemotherapy ... German breast cancer patients Journal of Behavioral Medicine, 29(6), 533-547 200 University of Ghana http://ugspace.ug.edu.gh Appendix A: Background Information form Section A Demographic Information ... http://ugspace.ug.edu.gh Appendix C: Information Sheet and Consent form CONSENT FORM Title: Exploring Factors that Influence Resilience among Breast Cancer Women who Received Chemotherapy in the Accra Metropolis
Ngày tải lên: 31/07/2019, 00:38
Impact of vitamin D on pathological complete response and survival following neoadjuvant chemotherapy for breast cancer: A retrospective study
... breast cancer patients undergoing NAC Keywords: Vitamin D, Neo-adjuvant breast cancer, pCR Background Neoadjuvant chemotherapy (NAC) has become a standard of care in locally advanced breast cancer, ... sufficiency for improving survival of patients with breast cancer Anticancer Res 2014;34:1163–6 30 Vrieling A, Hein R, Abbas S, et al Serum 25-hydroxyvitamin D and postmenopausal breast cancer survival: ... follow-up Breast cancer patients are more frequently affected by a VD deficiency than the general population Seventy to 80% of these patients have VD level below the lower limit of normal at breast cancer
Ngày tải lên: 03/07/2020, 01:26
Prediction of survival after neoadjuvant chemotherapy for breast cancer by evaluation of tumor-infiltrating lymphocytes and residual cancer burden
... Asano et al BMC Cancer (2017) 17:888 Page of 10 Fig On ROC curve analyses in all breast cancer and TNBC patients ROC analysis showed that, for all breast cancer patients, the results for the RCB-TILs ... RCB-TILs-positive patients than for RCB-TILs-negative patients in all patients (p < 0.001, log-rank) (a), TNBC patients (p < 0.001, log-rank) (b), HER2BC patients (p = 0.007, log-rank) (c), and HRBC patients ... lymphocytes, RCB residual cancer burden, TNBC triple-negative breast cancer, HER2BC human epidermal growth factor receptor 2-enriched breast cancer, HRBC hormone receptor-positive breast cancer, pCR pathological
Ngày tải lên: 23/07/2020, 23:58
The E2F4 prognostic signature predicts pathological response to neoadjuvant chemotherapy in breast cancer patients
... and RD patients, we calculated an E2F4 iRAS for each tumor in the Hatzis et al dataset, which contains gene expression and clinical information for patients who underwent neoadjuvant chemotherapy ... chemotherapy response in breast cancer E2F4 individual regulatory activity scores were calculated for 1129 patient samples across independent breast cancer neoadjuvant chemotherapy datasets Accuracy ... managing patients with earlystage breast cancer [1] In large or inoperable tumors, this therapy has been shown to substantially reduce tumor size allowing for easier removal and potentially breast
Ngày tải lên: 06/08/2020, 07:53
Weight change during chemotherapy in breast cancer patients: A meta-analysis
... gain in women with breast cancer during chemotherapy [1–8] Several reviews reported body weight gain during chemotherapy for breast cancer patients [9–15] Weight gain during chemotherapy was first ... weight”, ? ?breast cancer? ??, ? ?breast neoplasm”, ? ?breast carcinoma”, ? ?breast tumor”, ? ?breast tumour”, ? ?breast adenoma”, “mamma,” ? ?chemotherapy? ??, “chemo” and “cytostatic” (see Additional file for more ... significant weight gain during chemotherapy for women with early stage breast cancer Treatment for breast cancer has changed over time Before the 1990s, only CMF was used as chemotherapy regime, while
Ngày tải lên: 19/09/2020, 21:45
Overexpression of synuclein-γ predicts lack of benefit from radiotherapy for breast cancer patients
... and mortality rate of breast cancer are still raising [1] In 2013, breast cancer accounted for 25 % of total cancer cases and 15 % of cancer- related deaths worldwide [1] For decades, surgical ... Min et al BMC Cancer (2016) 16:717 Background Breast cancer is the most frequently diagnosed cancer among females worldwide [1] In more developed countries like the U.S., breast cancer death rates ... and improve the prognosis of patients with breast cancer, it is also notorious for comprehensive side effects, hence only a selected group of patients can benefit Therefore, the screening of molecular
Ngày tải lên: 20/09/2020, 17:57
Implication from thyroid function decreasing during chemotherapy in breast cancer patients: Chemosensitization role of triiodothyronine
... serum samples of breast cancer patients and 316 samples of breast benign lesion patients at initial diagnosis were analyzed for thyroid hormones Thirty-seven of 224 breast cancer patients were diagnosed ... In cancer patients, thyroid function is thought to be vulnerable to chemotherapy, as hypothalamic-pituitary axis is active and chemotherapy is systemic therapy for patients The influence of chemotherapy ... are highly curable with chemotherapy or combination of surgery and chemotherapy, even with widespread metastases For breast cancer patients, studies did not directly show chemotherapy can influence
Ngày tải lên: 05/11/2020, 06:53
Prognostic impact of AJCC response criteria for neoadjuvant chemotherapy in stage II/III breast cancer patients: Breast cancer subtype analyses
... BMC Cancer (2016) 16:515 DOI 10.1186/s12885-016-2500-1 RESEARCH ARTICLE Open Access Prognostic impact of AJCC response criteria for neoadjuvant chemotherapy in stage II/III breast cancer patients: ... of neoadjuvant chemotherapy before definitive surgery, the patients were reexamined for response evaluation Thereafter, the patients received curative surgery followed by adjuvant chemotherapy ... prognostic information In this study, we classified breast cancer patients into four subgroups, namely luminal A (LA), luminal B (LB), HER2 enriched (HER2), and triple-negative breast cancer (TNBC),
Ngày tải lên: 20/09/2020, 14:08
Báo cáo y học: "Down-regulation of kallikrein-related peptidase 5 (KLK5) expression in breast cancer patients: a biomarker for the differential diagnosis of breast lesions" doc
... histological features of breast cancer patients, aiming to examine its clinical value for the discrimination of the cancerous from non-cancerous breast lesions Materials and methods Breast tissue specimens ... expression prognostic value in breast cancer patients, whereas the KLK5 expression quantification proved to be an independent biomarker for the prediction of breast cancer patients? ?? DFS and OS [30] ... physiology and cancer Therefore, KLK5 expression quantification is critical for both the discovery of the early cellular and molecular alterations in breast cancer cells, as well as for the identification
Ngày tải lên: 13/08/2014, 13:20
Age-related microRNAs in older breast cancer patients: Biomarker potential and evolution during adjuvant chemotherapy
... adjuvant chemotherapy (docetaxel and cyclophosphamide, TC) for invasive breast cancer (chemo group, CTG, n = 46) A control group of older breast cancer patients without chemotherapy was included for ... and cancer, but the impact of chemotherapy on age-related miRNAs has barely been studied Our aim was to examine whether chemotherapy accelerates the aging process in elderly breast cancer patients ... BMC Cancer (2018) 18:1014 Background (Breast) cancer treatment in the elderly represents a major challenge in clinical oncology Despite their important representation within the overall breast cancer
Ngày tải lên: 03/07/2020, 00:52
Monitoring the responsiveness of T and antigen presenting cell compartments in breast cancer patients is useful to predict clinical tumor response to neoadjuvant chemotherapy
... signed an informed consent form before blood samples were taken A total of 560 patients with pathological diagnosis of breast cancer were interviewed at the Instituto Nacional de Cancerología ... immunological performance of T and APC compartments in peripheral blood of these patients before and after chemotherapy We found that the overall suppression of these two compartments perceived before treatment ... readouts in PBMCs obtained from a total of 17 breast cancer patients before, and after neoadjuvant anti-tumor therapy with A/C Results: The results show that before treatment, T cells and DCs, exhibit
Ngày tải lên: 24/07/2020, 00:17
Temporal influence of endocrine therapy with tamoxifen and chemotherapy on nutritional risk and obesity in breast cancer patients
... stated Lima et al BMC Cancer (2017) 17:578 Background Breast cancer (BC) accounts for 29% of all new cases of cancer in women, being the second leading cause of death [1] In patients treated with ... nutritional risk and obesity and its association with CT in breast cancer patients Methods: In this cross-sectional study, 84 breast cancer surviving women were evaluated during endocrine therapy ... tamoxifen for the first years; group 2, women using tamoxifen between and years; Group 3, women using tamoxifen for more than years; CT, chemotherapy; TMX, tamoxifen Lima et al BMC Cancer (2017)
Ngày tải lên: 06/08/2020, 05:02
Exercise as a diagnostic and therapeutic tool for preventing cardiovascular morbidity in breast cancer patients – the BReast cancer EXercise InTervention (BREXIT) trial protocol
... endocrine therapy for breast cancer J Natl Cancer Inst 2008;100(4):252–60 Colzani E, Liljegren A, Johansson ALV, Adolfsson J, Hellborg H, Hall PFL, Czene K Prognosis of patients with breast cancer: causes ... KD, Jemal A Cancer statistics, 2016 CA Cancer J Clin 2016; 66(1):7–30 Australian Institute of Health and Welfare Cancer Australia: Breast cancer in Australia Cancer series no 71 Edited by AIHW, ... in which patients will be provided a copy of the Cancer Council Australia booklet entitled “Exercise for People Living with Cancer. ” Exercise will then be left to the Foulkes et al BMC Cancer (2020)
Ngày tải lên: 06/08/2020, 05:32
Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers
... [26] Methods Patients During the study period, a total of 1371 BC patients were tested Two cohorts of patients are described in this report: Cohort 1: Patients tested at The Breast Cancer Surgery ... ovarian cancer [13–22] The American Society of Clinical Oncology (ASCO), The National Comprehensive Cancer Network (NCCN) in the US and the Norwegian Breast Cancer Group (NBCG) all have guidelines for ... Grindedal et al BMC Cancer (2017) 17:438 DOI 10.1186/s12885-017-3422-2 RESEARCH ARTICLE Open Access Current guidelines for BRCA testing of breast cancer patients are insufficient to
Ngày tải lên: 06/08/2020, 06:03
Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy
... patients Keywords: Early breast cancer, Polymorphisms, Adjuvant chemotherapy, Toxicity, Prognosis Background Breast cancer (BC) currently accounts for 20% of all female cancers worldwide and is ... was performed for MTHFR, RFC1 and GSTP1, while PCR for TS, GSTT1 and GSTM1 genes Results: Among the 244 patients consecutively enrolled, 48.7% were treated with FEC and 51.3% with CMF Patients ... associated with toxicity and survival in patients with early breast cancer (EBC) treated with adjuvant chemotherapy (CT) Methods: This prospective trial included patients with stage I–III BC subjected
Ngày tải lên: 06/08/2020, 06:25
Pretreatment glycemic control status is an independent prognostic factor for cervical cancer patients receiving neoadjuvant chemotherapy for locally advanced disease
... survival outcomes for LACC patients [20] There are reports that cancer patients with hyperglycemia have a poor response to chemotherapy [6, 21–23] Moreover, for diabetic cancer patients, poor glycemic ... of survival and tumor response to chemotherapy for patients receiving NACT for LACC Keywords: Diabetes mellitus, Hemoglobin A1c, Cervical cancer, Neoadjuvant chemotherapy, Prognosis * Correspondence: ... response to chemotherapy in patients receiving neoadjuvant chemotherapy (NACT) for locally advanced cervical cancer (LACC) Methods: A retrospective cohort study was conducted to examine LACC patients
Ngày tải lên: 06/08/2020, 06:36
CYP1A2 – a novel genetic marker for early aromatase inhibitor response in the treatment of breast cancer patients
... Simonsson et al BMC Cancer (2016) 16:256 Background Breast cancer is one of the leading causes of cancer morbidity and mortality among women worldwide [1] The majority of breast cancer patients have ... 634 primary breast cancer patients between October 2002 and October 2008 Patients were followed from inclusion to the first breast cancer event or distant metastasis, respectively, and patients ... in breast cancer patients Breast Cancer Res Treat 2008;112(1):89–98 Artigalas O, Vanni T, Hutz MH, Ashton-Prolla P, Schwartz IV Influence of CYP19A1 polymorphisms on the treatment of breast cancer
Ngày tải lên: 21/09/2020, 09:43
A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients
... variants modulate cancer specific survival in breast cancer patients depending on chemotherapy These germline SNPs could contribute towards the design of predictive tests for breast cancer patients Keywords: ... 3,813 postmenopausal breast cancer patients, genotype information on SNPs in DNA repair genes was available for 1,639 patients We further excluded patients with previous non -breast tumour (n = ... affect therapeutic success and cancer specific survival in breast cancer patients In a prospective breast cancer patient cohort from Germany [19], we assessed whether cancer specific survival is
Ngày tải lên: 22/09/2020, 22:59
Eligibility criteria for intraoperative radiotherapy for breast cancer: Study employing 12,025 patients treated in two cohorts
... Cancer 2014, 14:868 http://www.biomedcentral.com/1471-2407/14/868 RESEARCH ARTICLE Open Access Eligibility criteria for intraoperative radiotherapy for breast cancer: study employing 12,025 patients ... contained 7580 patients The second cohort was monocentric (cohort 2) comprising 4445 patients All patients underwent conservative surgery followed by external radiotherapy for invasive breast cancer ... Michel Resbeut1 Abstract Background: We wished to estimate the proportion of patients with breast cancer eligible for an exclusive targeted intraoperative radiotherapy (TARGIT) and to evaluate
Ngày tải lên: 30/09/2020, 15:12