chemoattractant cytokines were more prominent in the lung airways of infected caspase 1 deficient mice
The role of caspase 1 in a murine model of influenza pneumonitis, and studies on cell death inhibitors in vitro
Ngày tải lên :
13/10/2015, 16:41
... death in the lungs of caspase- 1 knock-out 13 8 4.3.9 Cytokine expression – Chemoattractant cytokines were more prominent in the lung airways of infected caspase- 1- deficient mice 13 9 4.3 .10 Caspase- 1 ... virus infection 13 2 4.3.3 Up-regulation of caspase- 1 in the lungs of infected wild-type mice 13 3 4.3.4 Higher viral load present in the lungs caspase- 1- deficient mice at day postinfection 13 4 ... Biochemistry of caspase- 1 14 1. 8.2 Substrates of caspase- 1 14 1. 8.3 Synthetic caspase inhibitors 15 1. 9 Animal models in influenza pneumonia 16 1. 10 Caspase- 1 and...
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Báo cáo y học: " Abscopal effect of radiation on lung metastases of hepatocellular carcinoma: a case report" pptx
Ngày tải lên :
11/08/2014, 00:23
... http://www.jmedicalcasereports.com/content/5 /1/ 111 Page of 10 11 12 Figure CT scan showing the absence of both lung metastases, which regressed after radiation therapy 13 14 mediastinal resulted in tumor mass regression in an untreated ... and approved the final manuscript Competing interests The authors declare that they have no competing interests Received: 19 May 2 010 Accepted: 19 March 2 011 Published: 19 March 2 011 References ... but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody Clin Cancer Res 2009, 15 (17 ):5379-5388 doi :10 .11 86 /17 52 -19 47-5 -11 1 Cite this...
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Sculpture of the Exposition Palaces and Courts Descriptive Notes on the Art of the Statuary at the Panama-Pacific International Exposition San Francisco ppt
Ngày tải lên :
15/03/2014, 14:20
... these works among us Who is going to take the lead? The Contents Introduction The Fountain of Energy The Mother of Tomorrow The Nations of the Occident The Nations of the Orient The Alaskan The ... Falconer, the Indian Prince and Spirit of the East, the Lama, the Mohammedan Warrior, the Negro Servitor, the Mongolian Warrior On they come to join the Nations of the West in the great Court of the ... Lama The Genius of Creation The Rising Sun Descending Night Winter The Portals of El Dorado Panel of the Fountain of El Dorado Youth The American Pioneer Cortez The End of the Trail Panel from the...
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Effects of short term exposure to air pollution on hospital admissions of young children for acute lower respiratory infections in ho chi minh city
Ngày tải lên :
13/09/2015, 17:48
... per 10 ug/m3 15 LAG C2: NO2 + O3 15 25 C1 C2 C3 S C1 C2 C3 -5 -10 S C1 C2 C3 S C1 C2 C3 -10 S C1 C2 C3 S C1 C2 C3 S C1 C2 C3 S C1 C2 C3 Discussion Preliminary results suggest that increased concentrations ... per 10 ug/m3 C3 SO2 NO2 50 S 30 30 20 20 10 10 S: NO2 C2: NO2 + O3 -10 C3: NO2 + SO2 C1: NO2 + PM10 -10 -20 -20 S C1 C2 C3 S C1 C2 C3 S C1 C2 C3 S C1 C2 C3 Co-pollutant models: % increase in pneumonia ... ug/m3 C1 10 -5 -10 S 15 10 -5 -10 Percent change per 10 ug/m3 LAG 20 10 25 Percent change per 10 ug/m3 10 LAG 0-5 Percent change per 10 ug/m3 Percent change per 10 ug/m3 Percent change per 10 ug/m3...
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Báo cáo y học: "Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice" pot
Ngày tải lên :
12/08/2014, 11:22
... 11 (11 ,0) Diseases and disorders Inflammatory disease 5.92E-07 - 3 .11 E-02 11 (11 ,0) Skeletal and muscular disorders 5.92E-07 - 3.04 E-02 11 (11 ,0) Organismal injury and abnormalities 14 (3 ,11 ) ... al.: Indomethacin reduces lung adenoma number in A/J mice Anticancer Res 20 01, 21( 3B) :17 49 -17 55 doi: 10 .11 86 /14 65-99 21- 11- 70 Cite this article as: Zeidler-Erdely et al., Response of the mouse lung ... exploring the lung toxicity of welding fume in vivo, specific knowledge of the genes expressed in the context of welding fume-induced lung toxicity is only beginning to emerge [10 -13 ] Recent...
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Báo cáo y học: "Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice" ppt
Ngày tải lên :
12/08/2014, 14:20
... use that may be made of the information it contains Page 12 of 13 (page number not for citation purposes) Respiratory Research 2009, 10 :6 References 10 11 12 13 14 15 16 17 18 19 20 Dorfmuller P, ... injection of endotoxin and cytokines II Interleukin-6 and transforming growth factor beta inhibit acute inflammation Am J Pathol 19 91, 13 8(5) :10 97 -11 01 Aderka D, Le JM, Vilcek J: IL-6 inhibits ... circulating levels and pulmonary expression of various inflammatory cytokines and chemokines including interleukin-1beta (IL -1 ), IL-6, monocyte chemoattractant protein (MCP -1) , RANTES, and fractalkine...
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Báo cáo sinh học: " Development of a model for marburgvirus based on severe-combined immunodeficiency mice" doc
Ngày tải lên :
18/06/2014, 18:20
... values of mice infected with 'scid-adapted' MARV Scid mice were infected with 10 00 pfu of the indicated 'scid-adapted' MARV (Ci67 P15, Musoke P10 or Ravn P10) (A) The weight of groups of 10 mice was ... biodefence: Therapeutic developments and diagnostics Nat Rev Drug Disc 2005, 4:2 81- 297 Page 12 of 13 (page number not for citation purposes) Virology Journal 2007, 4 :10 8 10 11 12 13 14 15 16 17 18 19 ... amongst the liver homogenates with increasing passage in mice (Figure 1D–F) The increase in viral titer in the day liver homogenates seemed to correspond with a decrease in the MTD of the inoculated...
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báo cáo hóa học: " The effect of consequent exposure of stress and dermal application of low doses of chlorpyrifos on the expression of glial fibrillary acidic protein in the hippocampus of adult mice" pptx
Ngày tải lên :
20/06/2014, 00:20
... 662.9 ± 15 6 640.6 ± 95 504.3* ± 11 6 CPF 0 .1 814 .7 ± 15 8 613 .8 ± 12 5 CPF 0 .1( s) 748.5* ± 18 5 564.5 ± 10 0 5 01* ± 11 9 CPF 0.2 768.7* ± 2 01 578.7* ± 10 3 483.3* ± 16 7 CPF 0.2(s) 746.6* ± 16 3 525.7* ... vaporisation of the CPF solution The foil wrappings were left on the tail for hours After removal of the wrappings, traces of CPF solution were removed by dipping the tails of all mice in clean water ... two random areas in stratum oriens of the hippocampus were examined The areas of the captured images were constant Astrocytic cell counts were then performed in the regions of the hippocampus...
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Báo cáo hóa học: " Development of a model for marburgvirus based on severe-combined immunodeficiency mice" docx
Ngày tải lên :
20/06/2014, 01:20
... values of mice infected with 'scid-adapted' MARV Scid mice were infected with 10 00 pfu of the indicated 'scid-adapted' MARV (Ci67 P15, Musoke P10 or Ravn P10) (A) The weight of groups of 10 mice was ... biodefence: Therapeutic developments and diagnostics Nat Rev Drug Disc 2005, 4:2 81- 297 Page 12 of 13 (page number not for citation purposes) Virology Journal 2007, 4 :10 8 10 11 12 13 14 15 16 17 18 19 ... amongst the liver homogenates with increasing passage in mice (Figure 1D–F) The increase in viral titer in the day liver homogenates seemed to correspond with a decrease in the MTD of the inoculated...
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Báo cáo khoa học: "Effects of Combination Dietary Conjugated Linoleic Acid with Vitamin A (Retinol) and Selenium on the Response of the Immunoglobulin Productivity in Mice" pdf
Ngày tải lên :
07/08/2014, 17:22
... purity of 76 .14 45%, the CLA (c9, t 11 isomer) was composed of c9, t 11, 27%; c12, t10, 26%; c18, t0, 5%; c18, t1, 27%; c18, t2, 0%; c16, t0, 13 % CLA at dose of 0.5% and 1. 5% was given at 13 3.5 mg/kg/day ... bands were carefully obtained from the tubes The cells were washed again, the density was calculated as 1. 5x106 cells/ml, and then cells were cultured in 96 well plates containing 10 % fetal bovine ... collection, the end of the duodenum and the cranial part of the cecum were tied and both ends were cut One end of the small intestine was at the stand and a conical tube was placed at the other end Then...
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Báo cáo khoa học: "Low dietary inorganic phosphate affects the lung growth of developing mice" pps
Ngày tải lên :
07/08/2014, 23:22
... 4E-PB1 and p-4E-BP1 protein in the lungs of mice fed a low Pi diet (0 .1% Pi) or a normal (0.5% Pi) diet for weeks (A) The expressions of mTOR, 4E-PB1 and p-4E-BP1 protein in the lungs (B) The ... protein in the lung (B) The bands -of- interests were further analyzed by using a densitometer (C) Immunohistochemical measurement of FGF-2 in the lung of transgenic mice The dark brown color indicates ... and the other group was put on a low phosphate diet containing 0 .1% Pi (low Pi) All the diets were prepared according to the guideline of the American Institute of Nutrition [23] The mice were...
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Báo cáo khoa học: "Early administration of IL-6RA does not prevent radiation-induced lung injury in mice" pot
Ngày tải lên :
09/08/2014, 08:23
... cAnNCrj mice were obtained from Charles River 1- 2 weeks before testing Mice were maintained according to the institutional animal care use committee guidelines The mice were anesthetized by i.p injection ... according to the instructions of the manufacturer Lung hydroxyproline determination Collagen deposition was estimated by determining the hydroxyproline content of the left lung Samples were hydrolyzed ... Bromberg JF: Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas J Clin Invest 2007, 11 7:3846-3856 doi: 10 .11 86 /17 48- 717 X-5-26 Cite this...
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Báo cáo y học: "Gender-specific effects of HIV protease inhibitors on body mass in mice" ppt
Ngày tải lên :
10/08/2014, 05:20
... Med 19 95, 1( 11) :11 55 -11 61 Caro JF, Sinha MK, Kolaczynski JW, Zhang PL, Considine RV: Leptin: the tale of an obesity gene Diabetes 19 96, 45 (11 ) :14 55 -14 62 Riddle TM, Fichtenbaum CJ, Hui DY: Leptin ... background or the age of the mice This difference was observed both in circulating levels of leptin in the serum as well as at the level of leptin expression in abdominal white adipose tissue In the present ... expression in the mouse Obes Res 2004, 12 (9) :14 81- 14 91 Ahren B: Diurnal variation in circulating leptin is dependent on gender, food intake and circulating insulin in mice Acta Physiol Scand 2000, 16 9(4):325-331...
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Báo cáo y học: "Effect of smoking on lung function, respiratory symptoms and respiratory diseases amongst HIV-positive subjects: a cross-sectional study pptx
Ngày tải lên :
10/08/2014, 05:21
... function2, n (%) 96.2 (12 .5) 16 (17 ) 88.2 (16 .7) (32) 91. 4 (13 .7) (18 %) 94.6 (11 .7) (17 %) 97 .1 (14 .4) 12 (23%) 94.5 (13 .8)** 24 (20) Asthma history, n (%) (7) (29) (7) (13 ) (14 ) 13 (11 )** Asthmatic by ... pentamidine: A 5-year surveillance study in HIV -infected patients Chest 2003, 12 3 :19 83 -19 87 15 Beck G, Doyle C, Schachter E: Smoking and lung function Am Rev Respir Dis 19 81, 12 3 :14 9 -15 5 16 Dockery ... veterans Journal of General Internal Medicine 2005, 20 :11 42 -11 45 11 Moscato G, Maserati R, Marraccini P, Caccamo F, Dellabianca A: Bronchial reactivity to methacholine in HIV -infected individuals...
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Báo cáo y học: " A QTL on mouse chromosome 12 for the genetic variance in free-running circadian period between inbred strains of mice" potx
Ngày tải lên :
10/08/2014, 09:20
... AhR strains in activity as a function of mice of Daily profile of locomotor activity of representative mice of the B6 and AhR strains in LD 12 :12 as a function of circadian time Profiles were generated ... cycling of expression Apparently, zinc finger proteins can modulate the circadian clock The promoter region of mPer1 contains targets for zinc finger protein binding and is essential in NG108 15 ... Zfp277 (zinc finger protein 277) Expression analysis The expression analysis of whole brain had 29 probe-sets representing 14 of 15 known genes in the QTL, and 12 probe-sets representing of the 12 ...
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Báo cáo y học: "Early Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response" ppt
Ngày tải lên :
11/08/2014, 08:21
... Journal of Inflammation 2005, 2 :16 References 10 11 12 13 14 15 16 17 18 19 20 21 22 Bals R, Hiemstra PS: Innate immunity in the lung: how epithelial cells fight against respiratory pathogens Eur ... of chemokines or cytokines found to be elevated by poly(I:C) stimulation including IL-6, IL-8, MIP-3α and GRO-α Interestingly, flagellin also induced IP -10 secretion in SAEC pointing to the induction ... stimulation of SAEC with the TLR3 ligand poly(I:C) resulted in the most pronounced inflammatory response regarding the secretion of cytokines and chemokines including an increased release of IL-6,...
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Báo cáo khoa học: " A simple and rapid Hepatitis A Virus (HAV) titration assay based on antibiotic resistance of infected cells: evaluation of the HAV neutralization potency of human immune globulin preparations" potx
Ngày tải lên :
12/08/2014, 04:21
... representation of the genome of the HAV-Bsd Schematic representation of the genome of the HAV-Bsd The infectious cDNA of wild type HM -17 5 strain of HAV (wt HAV) containing a A 216 V amino acid substitution in ... globulin for prophylaxis of infectious hepatitis Am J Epidemiol 19 68, 87:539-550 Page of (page number not for citation purposes) Virology Journal 2008, 5 :15 5 10 11 12 13 14 15 16 17 18 19 20 21 22 ... which codes for the infectious cDNA of the wild type HM -17 5 strain of human HAV containing a A 216 V substitution at amino acid 216 of the 2B protein and a blasticidin resistance gene at the 2A-2B junction...
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Báo cáo y học: " Therapeutic efficacy of alpha-1 antitrypsin augmentation therapy on the loss of lung tissue: an integrated analysis of 2 randomised clinical trials using computed " potx
Ngày tải lên :
12/08/2014, 11:22
... FEV1 (L), median 1. 63 ± 0.49 1. 63 1. 72 ± 0.53 1. 61 1.44 ± 0.60 1. 14 1. 35 ± 0.62 1. 14 1. 55 ± 0.56 1. 47 1. 48 ± 0.63 1. 38 0.553 FEV1% predicted, median 47.3 ± 11 .4 48.6 51. 2 ± 14 .5 49.0 46.3 ± 19 .6 ... (n = 59) p value 11 4 ± 14 .7 59.7 ± 16 .0 57.0 11 7 ± 16 .4 60 .1 ± 16 .3 65.0 94 ± 21. 8 50.7 ± 19 .5 47.6 98 ± 23.2 52.2 ± 15 .2 50 .1 103 .1 ± 21. 8 56.3 ± 17 .3 56 .1 104.7 ± 23.9 55.7 ± 15 .9 56.0 0.789 ... TLC-adjusted PD15† (g•L -1) 59.9 ± 11 .03 62.98 ± 13 .49 54.6 ± 17 .4 53.9 ± 16 .0 57 .1 ± 15 .2 58.2 ± 15 .7 0.6 91 Lung volume (L) 5. 71 ± 1. 27 5.52 ± 1. 34 7.46 ± 1. 60 7.27 ± 1. 78 6. 61 ± 1. 67 6.35 ± 1. 69 0.300...
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Báo cáo y học: " Protective role of vascular endothelial growth factor in endotoxin-induced acute lung injury in mice" potx
Ngày tải lên :
12/08/2014, 15:21
... apoptosis in a single model of lung injury To evaluate the role of VEGF in the apoptosis of endothelial cells and their barrier function in the injured lung, we evaluated the effects of exogenous ... using a murine model of http://respiratory-research.com/content/8 /1/ 60 LPS-induced lung injury Using the lung specimens, TUNEL staining and immunostaining of caspase- 3, Bax, apoptosis inducing ... albumin (0 .1 mCi/ mouse) 15 before intratracheal administration of either PBS or LPS Two minutes before the end of the study, 13 1I-albuimn (0 .1 mCi/mouse) was injected to esti- Page of 13 (page...
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Báo cáo y học: " The role of endothelin-1 in hyperoxia-induced lung injury in mice" docx
Ngày tải lên :
12/08/2014, 16:20
... effects of ET -1 on the lungs; in particular, the effects of the exogenous administration of ET1 on the lung function have been successfully inhibited by the administration of these agents [11 ,14 ] ... FR139 317 or PD 14 5065 Br J Pharmacol 19 94, 11 1(4) :10 09 -10 16 Henry PJ, Carr MJ, Goldie RG, Jeng AY: The role of endothelin in mediating virus-induced changes in endothelinB receptor density in ... in the other groups of mice Discussion The involvement of ET -1 in the hyperoxia-induced lung function deterioration was characterized in detail in the present study by assessing the changes in...
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