chemical inhibitors of the kinase domain of the epidermal growth factor receptor

Báo cáo y học: " Rac and Rho driving tumor invasion: who’s at the wheel" docx

Báo cáo y học: " Rac and Rho driving tumor invasion: who’s at the wheel" docx

Ngày tải lên : 14/08/2014, 21:20
... depletion of Rac1 itself also reduced the fraction of elongated cells, while conversely, inhibitors of ROCK or myosin increased the levels of GTP-bound Rac (Rac-GTP) concomitantly with the fraction of ... reduced the proportions of elongated cells This evaluation of a set of melanoma cell lines makes a strong case for the importance of the biaxial signaling network identified in the control of melanoma ... is the initiation of epithelial cell-cell adhesion, where rounds of activation and de-activation of Rac at the contacting membrane lead to expansion of the contact zone between cells [22] Another...
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Tài liệu 80C51 family programmer’s guide and instruction set pptx

Tài liệu 80C51 family programmer’s guide and instruction set pptx

Ngày tải lên : 20/01/2014, 03:20
... the address of the next instruction and then pushes the 16-bit result onto the stack (low byte first), incrementing the Stack Pointer by two The high-order and low-order bytes of the PC are then ... through the Carry flag The eight bits in the Accumulator and the carry flag are together rotated one bit to the left Bit moves into the carry flag; the original state of the carry flag moves into the ... through the Carry flag The eight bits in the Accumulator and the carry flag are together rotated one bit to the right Bit moves into the carry flag; the original state of the carry flag moves into the...
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Tài liệu USAID/Haiti Maternal and Child Health and Family Planning Portfolio Review and Assessment pdf

Tài liệu USAID/Haiti Maternal and Child Health and Family Planning Portfolio Review and Assessment pdf

Ngày tải lên : 12/02/2014, 12:20
... at the root of the inability of state institutions to make effective use of existing resources to serve the needs of the Haitian people, as well as the disengagement of a significant majority of ... percent of these cases the aggressor was someone other than the partner or spouse These figures in all likelihood represent a severe underreporting of the true level of violence against women Other ... Together, these factors undermine the ability of the Haitian state to efficiently and effectively manage its scarce resources to improve access to and the quality of health services and the ability...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

Ngày tải lên : 14/02/2014, 18:20
... Consequently, the PH–TH domain doublet of ITK fuses directly with the linker B kinase region of SYK The PH domain of TFKs usually binds to phosphatidylinositol-3,4,5-trisphosphate, thereby bringing them ... of all mutations in the BTK gene are missense and some of these reduce the stability of the protein This is exemplified by mutations in the BTK motif of the Tec homology (TH) domain [18] This region ... identify individuals with mild disease, thereby providing the missing data The phenotype of XLA and the potential of BTK and ITK inhibitors The outcome of defective BTK signaling in humans has...
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Family Life, Reproductive Health, and Population Education: Key Elements of a Health-Promoting School docx

Family Life, Reproductive Health, and Population Education: Key Elements of a Health-Promoting School docx

Ngày tải lên : 22/03/2014, 12:20
... delay the initiation of intercourse, reduce the frequency of intercourse, reduce the number of sexual partners, or increase the use of condoms or other contraceptives (Kirby et al., 1994) The Centers ... liberty, and security of the person; rights relating to the foundation of families and of family life; rights relating to the highest attainable standard of health and the benefits of scientific progress, ... learning theories, such as social cognitive theory, social influence theory, social inoculation theory, cognitive behavioural theory, or the theory of reasoned action2 Last a sufficient length of time,...
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Báo cáo khoa học: Tec family kinases: Itk signaling and the development of NKT ab and cd T cells potx

Báo cáo khoa học: Tec family kinases: Itk signaling and the development of NKT ab and cd T cells potx

Ngày tải lên : 28/03/2014, 22:21
... re-examination of the role of Ras in the development of these cells seems to be war1976 ranted With regards to transcriptional targets of the Itk pathway, although the spotlight has been on NFAT, other factors ... surmise from these findings about the signals regulated by Itk downstream of the TCR during the development of these various subsets of T cells? Based on the studies to date, it is clear that the calcium ... [27] PLZF belongs to the BTB-zinc finger family of transcription factors and in the absence of PLZF, the numbers of mature iNKT cells is greatly reduced [28] The homeostasis of these cells is also...
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Báo cáo khoa học: The carbohydrate-binding module family 20 – diversity, structure, and function doc

Báo cáo khoa học: The carbohydrate-binding module family 20 – diversity, structure, and function doc

Ngày tải lên : 30/03/2014, 01:20
... separates the two domains of the enzyme [63] Interestingly, the linker of the A niger GA is 22 amino acids longer than that of H jecorina These two examples indicate that the modules of fungal ... upon the swapping of CBM20 of B macerans CGTase with that of A awamori GA Another intriguing point is the role of the two binding sites present in most CBM20s The different afnities of these ... Hence, the effects of in planta expression of SBDs are dependent both on the used SBD construct and on the genetic background of the host plant The above studies clearly demonstrate the potential of...
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family therapy concepts, process and practice

family therapy concepts, process and practice

Ngày tải lên : 29/05/2014, 16:15
... factors, whether biochemical or intrapsychic, belong just as much in the domain of the real-life practice of couple and family therapy as the interpersonal factors with which the field of family therapy ... outlined The first part of this volume contains a critical evaluation of the major schools of family therapy The major traditions are grouped together in terms of their central focus of therapeutic ... Street, Professor John Carpenter, Bebe Speed and Professor Bryan Lask at the editorial of ce of the Journal of Family Therapy; to Professor Terry Trepper, Editor of Journal of Family Psychotherapy;...
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The Impact of ParentalInvolvement  Parental Supportand Family Education on PupilAchievements and Adjustment A Literature Review

The Impact of ParentalInvolvement Parental Supportand Family Education on PupilAchievements and Adjustment A Literature Review

Ngày tải lên : 02/06/2014, 09:37
... consequence they assessed the degree of parent-teacher contact, the extent of parental involvement in school, the quality of the parent-teacher relationship, teacher’s perception of the parent, the extent ... informing the development of policy intended to close the social class gap in achievement 1.7 The aims of the review are to investigate the impact of: parental support (e.g the provision of parenting ... meet the needs of an anticipated lay readership of the report, statistical content has been kept to a minimum in the main body of the text Appendix B reports, in table form, the scale of the impact...
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Báo cáo hóa học: "The Pediatric Quality of Life Inventory™ (PedsQL™) family impact module: reliability and validity of the Brazilian version" pdf

Báo cáo hóa học: "The Pediatric Quality of Life Inventory™ (PedsQL™) family impact module: reliability and validity of the Brazilian version" pdf

Ngày tải lên : 18/06/2014, 22:20
... cross-cultural adaptation, the group of specialists stated that the concept of the impact of childhood cancer on the quality of life of the families used for development of the original instrument was ... Page of (page number not for citation purposes) Health and Quality of Life Outcomes 2008, 6:35 the health-related quality of life of parents/guardians The score is computed as the sum of the 20 ... understanding the questionnaire A synthesisversion was developed (T3) as a result of this process The third step consisted of a backtranslation of the synthesis-version (T3) by a professional,...
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báo cáo hóa học:" Research Article Strong Convergence of a New Iterative Method for Infinite Family of Generalized Equilibrium and Fixed-Point Problems of Nonexpansive Mappings in Hilbert Spaces" pptx

báo cáo hóa học:" Research Article Strong Convergence of a New Iterative Method for Infinite Family of Generalized Equilibrium and Fixed-Point Problems of Nonexpansive Mappings in Hilbert Spaces" pptx

Ngày tải lên : 21/06/2014, 11:20
... Then the sequence {xn } defined by 1.25 converges strongly to x∗ ∈ Ω, which is the unique solution of the variational inequality: x∗ PΩ I − A − γf x∗ 3.51 Remark 3.3 In the proof process of Theorem ... of others in the literatures and our result extends and improves the ones of Colao et al and some others 6 Fixed Point Theory and Applications Preliminaries Let C be a closed convex subset of ... 2α , then I − λA is a nonexpansive mapping of C into H If there exists u ∈ C such that v − u, Au ≥ 2.6 for all v ∈ C, then u is called the solution of this variational inequality The set of all...
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Báo cáo hóa học: "Research Article Some Characterizations for a Family of Nonexpansive Mappings and Convergence of a Generated Sequence to Their Common Fixed Poin" pdf

Báo cáo hóa học: "Research Article Some Characterizations for a Family of Nonexpansive Mappings and Convergence of a Generated Sequence to Their Common Fixed Poin" pdf

Ngày tải lên : 21/06/2014, 20:20
... if E has the Kadec-Klee property, the convergence is in the strong topology Kimura 21 obtained the further generalization of this theorem by using the Bregman projection; see also 22 Theorem ... Kadec-Klee property, the convergence is in the strong topology On the other hand, Ibaraki et al 20 proved the following theorem for a sequence of generalized projections in a Banach space Theorem 2.4 ... implies limn → ∞ yn − xn Then, the sequence {yn } of the domain of f, limn → ∞ Df yn , xn f f {ΠCn x} of Bregman projections converges strongly to ΠC0 x for all x ∈ C We note that the generalized duality...
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Báo cáo toán học: "On a new family of generalized Stirling and Bell numbers" pps

Báo cáo toán học: "On a new family of generalized Stirling and Bell numbers" pps

Ngày tải lên : 08/08/2014, 14:23
... w-weight of all of the members of L(n), the left-hand side by Theorem 5.1 As for the right-hand side, observe that the k-th term of the sum gives the total weight of all of the members of L(n) ... undisturbed Note that the ordering of B on the right has one more non-record low (the c) than the one of the left, whence the nrec values of the corresponding members of H − H∗ are of opposite parity ... defined the electronic journal of combinatorics 18 (2011), #P77 25 as before and rec(λ) counts all of the record lows of λ The product on the left-hand side of (44) then gives the total v-weight of...
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family therapy concepts process and practice phần 1 ppsx

family therapy concepts process and practice phần 1 ppsx

Ngày tải lên : 14/08/2014, 05:20
... factors, whether biochemical or intrapsychic, belong just as much in the domain of the real-life practice of couple and family therapy as the interpersonal factors with which the field of family therapy ... outlined The first part of this volume contains a critical evaluation of the major schools of family therapy The major traditions are grouped together in terms of their central focus of therapeutic ... Street, Professor John Carpenter, Bebe Speed and Professor Bryan Lask at the editorial of ce of the Journal of Family Therapy; to Professor Terry Trepper, Editor of Journal of Family Psychotherapy;...
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family therapy concepts process and practice phần 2 potx

family therapy concepts process and practice phần 2 potx

Ngày tải lên : 14/08/2014, 05:20
... which represented either the part of themselves that reflected the other side of the conflict (in the case of processing a dilemma) or the deceased or unavailable person (in the case of processing unfinished ... heterosexual peers, and to members of the family The more supportive the responses of others, the better the adjustment of the individual Stage models for the development of lesbian and gay couple relationships ... behaviour therapy programmes with their children and the application of the principles of social learning theory to marital therapy laid the foundations for the development of family and marital therapy...
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family therapy concepts process and practice phần 3 potx

family therapy concepts process and practice phần 3 potx

Ngày tải lên : 14/08/2014, 05:20
... other family members Over the course of therapy, the impact of this intervention of the beliefs and behaviour of the family is tracked The therapeutic style of this branch of the original Milan team ... Italy in the 1970s developed their own unique style This involved the use of fivepart therapy sessions; the use of co-therapy and a team behind a screen; a commitment to the guidelines of hypothesising, ... imagine they are planning go write an autobiography of their relationship and then be asked to write out a list of the chapter headings and a brief sketch of the contents of each of these chapters...
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family therapy concepts process and practice phần 4 potx

family therapy concepts process and practice phần 4 potx

Ngày tải lên : 14/08/2014, 05:20
... (1) the authenticity of the therapeutic alliance; and (2) the depth of clients’ emotional experiencing within therapy The more authentic the relationship between the therapist and clients, the ... psychologically denying the significance of the unresolved family -of- origin relationship The greater the degree of cut-off, the greater the probability of replicating the problematic family -of- origin relationship ... emphasised the importance of the therapist’s use of ‘self’ as critical for therapeutic change Satir represented aspects of the self in the ‘selfmandala’ as a set of concentric circles moving from the...
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family therapy concepts process and practice phần 5 pps

family therapy concepts process and practice phần 5 pps

Ngày tải lên : 14/08/2014, 05:20
... stay? Then the therapist helps the family construct an understanding of the change process by reviewing with them the problem, the formulation, their progress through the treatment programme and the ... REFORMULATION The assessment phase of the overall therapy process involves interviewing to check out the accuracy of hypotheses made during the planning phase and modifying these in the light of the information ... around the blocks Sixth, ask about the pros and cons of these courses of action Seventh, frame a therapeutic dilemma that outlines the costs of maintaining the status quo and the costs of circumventing...
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family therapy concepts process and practice phần 6 docx

family therapy concepts process and practice phần 6 docx

Ngày tải lên : 14/08/2014, 05:20
... Before therapy ended they were invited to read farewell letters to their mother at the grave and then to burn them This was the final mourning ritual Of course this therapy did not erase the pain ... sympathetic towards the parents and wish to see the child re-united with them In other instances, they are critical of the parents and want the child to remain in care for the long term With these ... to help the family reduce the risk of further violence, so that the child may be returned to the custody of the parents The parents may acknowledge their ambivalence but agree to attend therapy...
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