cellular and molecular aspects of adipose tissue

... processes by which cellular organisation emerges in embryos Although we often have very good descriptions of how a particular organ forms and of the nature of the participating cells and molecular constituents, ... form after two distinct tissues come together, and here we will examine the generation of the neural tube in the newt and the formation of the ducted submandibular glands of the mouse The latter ... Chapter covers the molecular basis of morphogenesis and discusses the roles played here by the extracellular environment, the cell membrane and the intracellular cytoskeleton Chapters and describe...

Ngày tải lên: 05/03/2014, 11:21

... reaction on related Molecular action of Pasteurella multocida toxin G-protein targets and with overlapping cellular outcomes, the sequence and structure of the activity domain of PMT differ considerably ... increased production of diacylglycerol [77], mobilization of intracellular Ca2+ pools [68,71,72,78], interconversion of GRP78 ⁄ BiP [79] and activation of protein kinase C-dependent and -independent ... Ga isoforms, as all of the Ga subunits have analogous active site Gln residues (equivalent to Gln204 of Gai1, Gln205 of Gai2, Gln229 of Ga12 ⁄ 13 and Glu209 of Gaq ⁄ 11) and share significant...

Ngày tải lên: 22/03/2014, 15:21

... known whether p-BSQ of CS causes apoptosis and emphysematous lung damage We have addressed this question for better understanding of the cellular and molecular mechanisms of emphysema, so that ... and Bcl-2 of the lung extracts of guinea pigs exposed to air or CS supplemented with A, Immunoblots of caspase 3, PARP, A, Immunoblots of caspase 3, PARP, Bax and Bcl-2 of the lung extracts of ... mean perimeter (contour length) of air space and A is the area of air space [6] The number of air spaces and the S/V values calculated after 7, 14 and 21 days of smoke exposure are significantly...

Ngày tải lên: 11/08/2014, 08:22

... (HN) B-D and I-K are higher magnification views of cleithrum boxed in A and H, respectively Operculum of a DMSO control (E-G) and Mtz treated larva (L-N) Note: Loss of CFP and absence of mineralization ... rerio), to gain better understanding of the cellular and molecular processes involved in skeletal development To examine the role of osteoblasts in development of the vertebral column, I created ... Regeneration of ablated osx:CFP-NTR cells Fig 10 Lrp5 and Sost are conserved at the sequence level Fig 11 Early embryonic expression of lrp5 and sost Fig 12 lrp5 and sost expression at 24 and 48 hpf...

Ngày tải lên: 10/09/2015, 08:43

... accumulation of toxins in adipose tissue was recently demonstrated by the observed increase in plasma levels of organochlorines released from adipose tissue during weight loss [7–9] The amount of pollutant ... concentrations of a common food pollutant, B[a]P, caused a rapid, direct and profound inhibition of adipose tissue lipolysis stimulated by epinephrine, dobutamine, salbutamol, BRL37344 and ACTH This ... Maurice and Erwan Magueur is greatly appreciated This work was supported by grants from the Lorraine Region and Urban Community of Grand Nancy (CUGN) and from the French Ministry of Research and...

Ngày tải lên: 30/03/2014, 11:20

... 5,16-androstadien-3β-ol O 4,16-androstadien-3-one Final products of androstenone sulfonation 5α-androsten-3β-ol (β-androstenol) SRD5A 3βHSD 3α-androstenol sulfate hydroxysteroid sulfotransferase 3β-androstenol ... 3β-androstenol sulfate HO 5α-androsten-3α-ol (α-androstenol) hydroxy-androstenone sulfate 3αHSD O androstenone hydroxy-androstenone hydroxysteroid sulfotransferase andro 3-enol sulfate andro 3-enol Figure ... cholesterol CYP21 andien-β synthetase (CYB5, CYP17…) 11-deoxycorticosterone 11- 4,16-androstadien-3-ene 4,16-androstadien- 3βHSD androstadienol sulfate hydroxysteroid sulfotransferase HO 5,16-androstadien-3β-ol...

Ngày tải lên: 14/08/2014, 13:21

... skatole SSC6, SSC13 and SSC14 [21] versus SSC7, SSC12 and SSCX [4] and for indole SSC13 and SSC14 [21] versus SSC2, SSC6 and SSC7 [4] The results of the assessment of lean and fat samples by a ... detected for androstenone [21] GENES INVOLVED IN THE METABOLISM OF ANDROSTENONE 3.1 Androstenone synthesis and metabolism Together with other 16-androstene steroids, androstenone (5 α-androst-16en-3-one) ... 5α-androsten-3α-ol α-androstenol 5α-androsten-3β-ol β-androstenol HO 5,16-androstadien-3β-ol andien-β synthetase (CYB5, CYP17…) HO Figure Main enzymes involved in the porcine metabolism of androstenone...

Ngày tải lên: 14/08/2014, 13:22

... white adipose tissue (WAT) and brown adipose tissue (BAT) WAT is the main site for the storage of energy in the form of triglycerides located in large lipid droplets that occupy most of intracellular ... Control of adipose tissue development Neural crest sox10 + Fig Putative stem cell lineages that give rise to white and brown adipose depots, highlighting the complexity of the origins of adipose tissues ... of adipose tissue development C Vernochet et al cytokines and hormones An excess of food intake can increase fat mass and disrupt energy balance Recent studies suggest that enlarged adipose tissue...

Ngày tải lên: 29/03/2014, 22:21

... quality of adipose tissue consistently point to the microvasculature and angiogenesis within adipose tissue as critical role players in adipose tissue health and expansion [3] Expansion of adult adipose ... adipocytes and the adipose microvascualture, and the marked similarities in tumor growth and hypoxia compared with those of adipose tissue expansion remain of great interest Adipose tissue and lymphatic ... modu- Adipose tissue circulation lator of adipose depot physiologies and their systemic impacts [6,10,11] Adipose tissue vasculature Adipose tissue possesses a relatively dense network of blood...

Ngày tải lên: 29/03/2014, 22:21

... bring to sampling and molecular study of viral crop diseases, we tested the efficacy of FTA for retrieval of viral pathogens from infected leaf tissues and for the detection of viralderived transgene ... consisted of 30 cycles of 94°C for min., 58°C for and 72°C for MSV F &MSVR : PCR conditions consisted of 30 cycles of 94°C for min, 59°C for and 72°C for mins C1F &C2R: PCR conditions consisted of 94°C ... collection and archiving of nucleic acids, either in their purified form or within pressed samples of fresh tissue Proprietary chemicals impregnated into the paper act to lyze cellular material and...

Ngày tải lên: 19/06/2014, 08:20

... bring to sampling and molecular study of viral crop diseases, we tested the efficacy of FTA for retrieval of viral pathogens from infected leaf tissues and for the detection of viralderived transgene ... consisted of 30 cycles of 94°C for min., 58°C for and 72°C for MSV F &MSVR : PCR conditions consisted of 30 cycles of 94°C for min, 59°C for and 72°C for mins C1F &C2R: PCR conditions consisted of 94°C ... collection and archiving of nucleic acids, either in their purified form or within pressed samples of fresh tissue Proprietary chemicals impregnated into the paper act to lyze cellular material and...

Ngày tải lên: 20/06/2014, 04:20

... higher levels of interleukin (IL)-13 and levels of fractalkine were detected In previous reports and studies, an inconsistent picture of the histological appearance of the adipose tissue in DD ... inflammation of the nerves in the adipose tissue of the painful sites [1,20], which has only been confirmed in one case report [21] As regards inflammatory signs in the adipose tissue in DD, leukocytes and ... infiltration of fibrotic elements and small angiomas [25], granulomas [16] and capillary microthrombi [26] The aim of this investigation was to examine the histological appearance of the adipose tissue...

Ngày tải lên: 11/08/2014, 03:20

... higher levels of interleukin (IL)-13 and levels of fractalkine were detected In previous reports and studies, an inconsistent picture of the histological appearance of the adipose tissue in DD ... inflammation of the nerves in the adipose tissue of the painful sites [1,20], which has only been confirmed in one case report [21] As regards inflammatory signs in the adipose tissue in DD, leukocytes and ... infiltration of fibrotic elements and small angiomas [25], granulomas [16] and capillary microthrombi [26] The aim of this investigation was to examine the histological appearance of the adipose tissue...

Ngày tải lên: 11/08/2014, 06:23

... subcutaneous adipose tissue was taken from the arm Control values of gene expression in adipose tissue were obtained from the analysis of biopsies of subcutaneous adipose tissue taken from the arms of ... overall clinical and biochemical features of the patient led to the diagnosis of APL The pattern of progressive loss of subcutaneous adipose tissue in the face and the upper part of the body was ... the analysis of the expression of genes characteristic of the adipocyte phenotype, as well as of genes involved in mitochondrial function and local inflammation status in adipose tissue, whose...

Ngày tải lên: 11/08/2014, 21:22

... emphasize the health of the newborn population, public health or the health level of a given society And then we would have to face the dilemma of eugenics Ethical and social aspects of evaluating ... perspective of consequences and control The myth of the objectivity of research is strong among health and economic researchers, and they may Wnd the explicit value requirements of ethics diYcult ... its group of target individuals What can be done? The current state of aVairs where the value of a health technology is judged only on the basis of some of its consequences, and the use of the technology...

Ngày tải lên: 01/11/2013, 08:20

... different aspects which we think are of great importance, namely aspects of information quality in workflows where digital services are a vital part and also in- and outsourcing aspects of digital ... 4.4 QUALITY ASPECTS OF THE SERVICE CONTEXT 4.5 CONNECTION TO THE REMAINING PART OF THE THESIS 4.6 SUMMARY OF CHAPTER 39 40 41 45 47 49 CHAPTER THEORETICAL ASPECTS OF INFORMATION AND COMMUNICATION ... engineering and validation of business processes PREFACE Life is strange and unpredictable, and the last two years of my life have been evidence of this In 2005, I felt unrestrained joy and happiness...

Ngày tải lên: 09/12/2013, 21:15

... various aspects of OFETs, including the synthesis of new materials, preparation and characterisation of organic thin films, characterisation of device properties and the development of new device ... fundamental understanding of the basic mechanism and properties of such OFETs, a national research initiative (supported by the DFG within the framework of the focus program 1121 OFET) was established ... transistors and to improving their performance and stability Section II: Molecular Compounds In the second section of the book entitled Molecular compounds” there are four papers describing molecular aspects...

Ngày tải lên: 16/02/2014, 19:20

... Purification of HYDBp and HYDJs tot, total proteins; ppt, precipitate fraction; sup, supernatant fraction; puri, purified proteins; M, molecular weight standards For the molecular weight standards, the bands ... positions of the Ca of Ala156 in HYDJs and the Ca of Met156 in HYDBp located in the SGL3, which leads to the increased size of the substrate binding pocket of HYDJs The side chain of Ala156 is ... performed using T-COFFEE [44] Docking simulation of substrate on the active site of HYDJs The substrate binding pockets of HYDJs and the mode of interaction between substrate and enzyme were analyzed...

Ngày tải lên: 18/02/2014, 08:20

... accurate measure of the koff parameter in CaM-bound eNOS and nNOS [58], and thus prevented assessment of the relative importance of conformational change rates versus rates of FMNH2 formation ... steps in the nNOS and eNOS flavoproteins (dissociation and association of the 4-electron reduced FNR–FMN subunit complex, kon and koff in Fig 5) Remarkably, the results suggest that koff is the sole ... in the CaM-free nNOS and eNOS, the rate of FMNH2 formation appears to be relatively fast and not rate limiting, and instead a specific conformational step (koff, dissociation of the reduced FMN...

Ngày tải lên: 18/02/2014, 11:20

... arises because of differences in the mass, frequency and consequently the transfer distance of H and D Experimentally, the identification of promoting vibrations is extremely challenging and, as yet, ... ½NADðPÞHŠ ðkoff =kon Þ þ ½NADðPÞHŠ ð7Þ In both MR and PETNR, at room temperature, kon, the apparent rate of coenzyme binding is $106 m)1Æs)1 The rate of NAD(P)H dissociation, koff, is $102 s)1 and the ... glycosylation and this approach has been used by Klinman and coworkers to study the viscosity dependence of the rate of hydride transfer in GO [70,71] These authors studied various glycoforms of the...

Ngày tải lên: 18/02/2014, 11:20