... intoxication of PMT Little is known about thecellular uptake mechanismsof PMT Bacterial protein toxins are known to utilize a number of different entry routes, andthe nature ofthe receptor often ... form, blocks the PMTinduced response [72], supporting the monomeric form of Gaq as the preferred substrate of PMT However, after the strong initial PMT-induced response, an uncoupling ofthe Gaq-coupled ... Although the precise localization ofthe domains responsible for receptor binding and translocation activity remains unclear, these domains are located in the N-terminus of each of these toxins and...
... during pyrolysis • The extent of vapor dilution in the reactor • The time and temperature history ofthe vapors in the reactor • The time and temperature history ofthe vapors in the heated transfer ... volume” ofthe solute, solubility is predicted This is satisfied if the distance from the center ofthe solvent sphere to the center ofthe solute sphere (Rij) is smaller than the radius ofthe solute ... fines • The water content ofthe bio-oil • The extent of contamination ofthe bio-oil during storage by corrosion or leaching ofthe containers • Exposure to air during storage • The length of storage...
... related to a change in the physiology ofthe compatible pollen tube, shifting from an autotrophic to a heterotropic type of nutrition callose Biochemical studies focused on pollinic and stigmatic proteins, ... male-female interactions (Gaude and Dumas, 1987) After silver nitrate staining, qualitative and quantitative differences could be observed, related to the presence of P nigra and P alba pollen tubes ... increasing protein bands were detectable, 0-20 h after pollination, only in compatible pollinated stigmas The concanavalin A-peroxidase reaction allowed the visualization of 15 stigmatic and pollinic...
... activation of caspase and cleavage of PARP There was a rise in the level ofthe proapoptotic Bax protein, but no rise in the level ofthe antiapoptotic Bcl-2, resulting in an increase ofthe Bax/ ... made in the trachea and one end of a tube (Tygon tube 020 ID 060 OD 10, Small Parts, Inc USA) was inserted into the trachea andthe other end drawn beneath the skin to open up at the back ofthe ... smokers The drawback of studying the effects of actual smoke exposure is likely the effect of already developed lesions in the lungs on theresponse to smoke [43] In order to understand the mechanism...
... Outcomes of Androgen Depletion The antiprostate cancer effects ofthe various androgen depletion strategies are similar, andthe clinical course is predictable: an initial response, then a period of ... quality of life Combined androgen blockade the administration of an antiandrogen plus a GnRH analogue or surgical orchiectomy—was designed to inhibit both testicular and adrenal androgens at the ... patients treated with radiation therapy and years of androgen depletion relative to radiation alone, was criticized for the poor outcomes ofthe control group Another showing a survival benefit...
... at bedtime) act by relaxing the smooth muscle ofthe bladder neck and increasing peak urinary flow rates No data show that these agents influence the progression ofthe disease Surgical approaches ... Over 5 how often past month, the have you found it difficult to postpone urination? Over the past month, how often have you had a weak urinary stream? Over the (No (1 (2 (3 (4 (5 how often past ... regardless ofthe size ofthe gland, while those with an inability to urinate, gross hematuria, recurrent infection, or bladder stones may require surgery In patients with symptoms, uroflowmetry...
... the antenna pattern width In this case, the bodies have to be in the wave (Fraunhofer) zone ofthe antenna, andthe antenna itself is in the Fraunhofer zone ofthe emitting body; therefore, the ... orthogonal to the line connecting the receiver andthe center of gravity ofthe radiating body We can direct the z-axis along this line The discussion in this case is about the reception of waves, the ... polarized in the plane The difference between these waves andthe xpolarized waves is that the power of their fluctuations will be detected by the receiver with the weight cos η, where η is the angle...
... Propagation and Remote Sensing ofthe Environment The first summand describes the soil radiation attenuated by absorption in the atmosphere, andthe second one describes the sum ofthe proper radiation of ... due to the fact that the result of integration depends on the order of integration due to the singularity ofthe integrands Substitution in Equation (9.47) ofthe obvious expressions ofthe eigenfunctions ... see that the first summand in the written solution satisfies Equation (9.86) on the right-hand side The two other summands define the solution ofthe homogeneous transfer equation with the condition...
... R-J and MW collected the clinical data and drafted the manuscript CK analyzed the data and wrote the manuscript The consequence of our findings was the interposition of carbon filters in the ... days when the hospital water supply was disinfected During dialysis, 706 arterial blood gas analyses were carried out, 89 of them on the days of water disinfection The results ofthe methemoglobin ... synchronize the exact time courses of hydrogen peroxide concentration in the hospital water supply and methemoglobinemia on the days of disinfection retrospectively Due to the retrospective nature of...
... namely, the precursor of membrane protein (prM), the envelope protein (E), andthe non-structural protein NS1 and accumulation of these in the ER may contribute to UPR induction These and several ... proliferation through the activation of specific components ofthe Unfolded Protein Response [31,32] These observations are also supported by the occurrence of replication and maturation of flaviviruses ... the ability of viruses to regulate cellular responses to infection is a key determinant for the physiological consequences of infection Since the activation ofthe UPR is on the one hand essential...
... analysis of similar disease pathways operating during early, intermediate and late stages ofthe development of human arthritis, although they will not be identical to those of RA On the other hand, ... indicating the complexity of interactions in the immune responseThe possible interactions of immune effector cells in the inflammatory phaseofthe arthritic joint are depicted in Figure KBN mice and ... opportunity to study the inflammatory phaseof arthritis without involving the priming phaseofthe immune response At the effector level, different pathways of complement activation and FcγR engagement...
... samples of mL were collected without anticoagulant immediately before the infusion (0 hour) and 1, 1.5, 4.5, and or hours (depending on the frequency of administration ofthe β-lactam) thereafter; these ... contributions FJ and PFL conceived the study protocol FST, FJ, PFL, TD, XW, BL and HS participated in the design and coordination ofthe study ID and PW performed the PK analyses FST, PFL, DDB, JLV and FJ ... characterization ofthe pharmacodynamic properties of these antimicrobials may lead to revisions in recommendations on dosing in severe infections, especially in theearlyphaseof severe sepsis and septic...
... fort near the lower towns, for the protection of themselves and their allies; andthe Cherokees on their part agreed to become the subjects ofthe King of Great Britain and hold their lands under ... healthy temperature ofthe air andthe mildness ofthe climate, the plenty of hunting, fishing and fowling, the facility of trade with the Indians andthe vast convenience of inland navigation or ... COLONIZATION OFTHE CUMBERLAND XVIII KING'S MOUNTAIN XIX THE STATE OF FRANKLIN XX THE LURE OF SPAIN THE HAVEN OF STATEHOOD THE CONQUEST OFTHE OLD SOUTHWEST Chapter I The Migration ofthe Peoples...
... biologists and wish became the father of thought andthe grandfather of observation: they claimed to see small but fully formed organisms in the sperm of men, horses, cocks and other animals and also ... distinct tissues come together, and here we will examine the generation ofthe neural tube in the newt andthe formation ofthe ducted submandibular glands ofthe mouse The latter example in particular ... development, the position of epithelial folding, the direction of spindle orientation and hence the direction of cell growth, the amount of sac contraction, andthe symmetry of epithelial drying...
... process of penetration begins The latter, depending on the host cell type andthe mode of entry [4,5], may require fusion ofthe virion envelope with the plasma membrane or with the membrane of an ... for the release ofthe viral nucleocapsid proximal to the nucleus the inoculation site; therefore, sores are most commonly found on the mouth or genital areas Medical professionals and others ... 2009 The Authors Journal compilation ª 2009 FEBS 7229 Cellularand viral mediators of HSV entry J Akhtar and D Shukla with a cellular membrane results in content mixing andthe eventual release of...
... showed that the time-frequency patterns at theearlyand late phases ofthe phrenic neurogram were the same for the 3–6 days old age group As maturation proceeds, theearlyphaseofthe phrenic ... Hz for theearlyand late phases ofthe phrenic neurogram during eupnea as well as the phrenic burst during gasping were estimated The mean ratios for the early, late phase during eupnea and gasping ... ratio ofthe total energies above and below 150 Hz for theearlyandThe mean well as the phrenic burst during gasping for different age groups late phases ofthe phrenic neurogram during The mean...
... behind the acetabular component in cases but the cup was grossly loose in only one of these There was evidence of gross collapse of a segment ofthe femoral head (evidenced by softening ofthe bone ... relief and return to their normal physical function One ofthe main proposed benefits of hip resurfacing arthroplasty is an improved range of movement and stability ofthe large diameter bearing These ... clinically, collected the data, organized and prepared the first draft ofthe paper SMA identified the topic as a subject of current interest, reviewed the patients clinically and edited the written paper...
... behind the acetabular component in cases but the cup was grossly loose in only one of these There was evidence of gross collapse of a segment ofthe femoral head (evidenced by softening ofthe bone ... relief and return to their normal physical function One ofthe main proposed benefits of hip resurfacing arthroplasty is an improved range of movement and stability ofthe large diameter bearing These ... clinically, collected the data, organized and prepared the first draft ofthe paper SMA identified the topic as a subject of current interest, reviewed the patients clinically and edited the written paper...
... the teeth, mouth or jaws and their treatment can affect the well-being and daily life of children and their families For each ofthe following questions, please mark an X in the box next to the ... probing/pressure, and denotes severe inflammation and spontaneous bleeding Face and content validity ofthe questionnaire were examined by the expert panel in order to assess the clarity ofthe wording ofthe ... order correlations between the ECOHIS scores andthe rating ofthe global oral health rating question, and between the child and family sections ofthe ECOHIS Interpretation of correlation coefficients...
... with the standard deviations ofthe mean value of proliferation to the same antigen in the peripheral blood compartment (b) The proliferative responses to SLO and TT observed in the patients in the ... for the kind gift ofthe Act-1 antibody We are grateful to Professor Mike Salmon and Professor Chris Buckley for critical reading ofthe manuscript We acknowledge the financial support ofthe ... Example of restricted pattern ofresponse to antigens Bars indicate mean proliferation and standard deviations of triplicate values (b) The proliferative responses to SLO and TT observed in the patients...