cell cycle transcription and translation
Báo cáo khoa học: The influence of cold shock proteins on transcription and translation studied in cell-free model systems pdf
... on the transcriptional or on the translational level, the system of combined transcription ⁄ translation was decoupled. The influence on the transcriptional level was investigated by in vitro transcription ... maximize the cell- free H-Ras expression by reducing Influence of CSPs on transcription and translation R. Hofweber et al. 4692 FEBS Journal 272 (2005) 4691–4702 ª 2005 FEBS translation ⁄ transcription ... proteins on transcription and translation studied in cell- free model systems Roland Hofweber 1 , Gudrun Horn 1 , Thomas Langmann 2 , Jochen Balbach 3 , Werner Kremer 1 , Gerd Schmitz 2 and Hans...
Ngày tải lên: 07/03/2014, 21:20
Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor
... mechanisms for controlling cell cycle progression (Morgan 1997; Zachariae and Nasmyth 1999). These studies and others demonstrated the universality of the cell Modeling Cell Cycle Control and Cancer with ... Nature 343:665–669 Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor 231 cycle, and strongly suggested that deregulation of the mechanisms controlling cell cycle progression could ... Orc1 and Mcm2–7) and DNA replication (e.g. Dhfr, Rnr, TK, TS and Polα). Many E2F target genes encode products in- volved in cell cycle progression (e.g. cyclins A and E, pRB, p107, E2F1–3) and apoptosis...
Ngày tải lên: 25/10/2013, 21:20
The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... most cell cycle responses. While each single pocket protein can mediate cell cycle arrest upon cell- cell contact, pRb is the critical mediator of cell cycle arrest upon growth factor deprivation and ... roles in controlling cell cycle exit upon growth-inhibiting signals. Only ablation of all pocket proteins fully alleviated a cell cycle arrest upon serum withdrawal, cell- cell contact inhi- bition, ... suppression and cell mortality. Cell 85:27–37 Serrano M, Lin AW, Mila EM, Beach D, Lowe SW (1997) Oncogenic ras provokes prema- ture cell senescence associated with accumulation of p53 and p16 Ink4a . Cell...
Ngày tải lên: 25/10/2013, 21:20
Báo cáo khoa học: 3 Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines potx
... during the cell cycle [13], upon exit and entry to the cell cycle both genes are controlled, at least in part, transcriptionally. Cdt1 and geminin are highly expressed in proliferating cells in ... upon cell cycle exit. To this effect, HFF cells were deprived of serum f or 48 h to induce cell cycle exit. Serum was th en r e-added a nd samples taken as cells progressed into the cell cycle. ... in G0 cells and induced upon cell cycle re-entry [23] and to be under the transcriptional c ontrol of E2F [24– 26]. We show here that, similar to Cdc6, Cdt1 mRNA levels are r educed in G0 and r...
Ngày tải lên: 07/03/2014, 16:20
cell cycle checkpoints and cancer
... the ligand for the flt2/3 receptor), erythropoietin (EPO), and others affect the growth and differentiation of these early hematopoietic precursor cells into cells of the myeloid, lymphoid, and ... knowledge of how cytokines affect cell growth, signal transduction, cell cycle progression, and apoptosis has been elucidated from research with IL-3 and IL-3-dependent cell lines. IL-3 was initially ... Schrader JW, Clark-Lewis I. A T cell- derived factor stimulating multipotential hemopoietic stem cells: molecular weight and distinction from T cell growth factor and T cell- derived granulocyte-macrophage...
Ngày tải lên: 10/04/2014, 11:13
Báo cáo khoa học: " Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines" pot
Ngày tải lên: 09/08/2014, 10:20
![báo cáo khoa học: " 6-Nitro-2-(3-hydroxypropyl)-1H-benz[de] isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosis" pot](https://media.store123doc.com/images/document/2014_08/11/medium_uxv1407640855.jpg)
Báo cáo y học: " Coordinate enhancement of transgene transcription and translation in a lentiviral vector" pps
Ngày tải lên: 13/08/2014, 09:21
Senescence and Cell Cycle Control
... RA (1995) The role of Rb in cell cycle control. Prog Cell Cycle Res 1:9–19 Senescence and Cell Cycle Control 259 eliminates telomere-mediated signaling, allowing cells to undergo transform- ation ... loss of G1 control and immortalization. Genes Dev 14:3037–3050 Senescence and Cell Cycle Control 267 Campisi J (2001) Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 11:S27–S31 Carnero ... mouse cells. p19 ARF is predominantly upregulated during senescence by oncogene activation and/ or oxidative stress Senescence and Cell Cycle Control 263 induction by controlling p16 INK4a (and...
Ngày tải lên: 25/10/2013, 21:20
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... Regulated During the Cell Cycle by a CDE ⁄ CHR Tandem Element and is Downregulated by p53 but not by p63 or p73. Cell Cycle 6, 853–862. 37 Yoshida K (2005) Cell- cycle- dependent regulation of the human and mouse ... p53. Cell cycle arrest can be medi- ated by p53 downregulating the transcription of central cell cycle regulators such as cyclin B, Cks1, Cdc2 and Cdc25C. CDE ⁄ CHR-dependent cell cycle- gene transcription ... encoded by cyclin B1 and cyclin B2 genes is Keywords cell cycle; cell cycle genes homology region (CHR); cell cycle- dependent element (CDE); DREAM complex; E2F Correspondence K. Engeland, Molecular...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Protein kinase CK2 activates the atypical Rio1p kinase and promotes its cell-cycle phase-dependent degradation in yeast pdf
... phase of the cell- division cycle. Therefore, we tested, using light microscopy and after DAPI staining, whether the slow growth yields a cell- cycle phenotype. Cells of the logarithmically ... which is stable throughout the cell cycle and highly resistant to proteolytic degradation [40]. Miscellaneous procedures Yeast were grown on standard media [41] and transformed as described by ... distribution of G 2 ⁄ M cells: the number of metaphase cells with a single DNA mass at the bud neck and the number of anaphase cells were increased slightly in the mutant (metaphase cells: 30.2% in the...
Ngày tải lên: 18/02/2014, 16:20
Báo cáo khoa học: Injection of poly(b-L-malate) into the plasmodium of Physarum polycephalum shortens the cell cycle and increases the growth rate pot
... in growth and cell cycle duration. However, we do not know how great an effect should be expected. If we assume that certain PMLA–protein complexes are involved in growth and cell cycle timing, ... proteins to nucleic acids, and it c ould affect cell g rowth a nd cell cycle duration. The distributing activity of PMLA and the efficiency of competition between PMLA and nucleic acids would both ... PMLA induced a strain specific enhancement of cell growth and an equal (between strains) shortening of the cell cycle. Materials and methods Strains and materials The following strains of P. polycephalum...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: "Braille Transcription and Mechanical Translation" pptx
... r"occupies three cells. In the second case the translation occupies three cells since "er" is a single -cell contraction. By rule 35 "o n er" is the correct translation of ... construction of the whole program and, in particular, of the dictionary. [ Mechanical Translation , vol.2, no.3, December 1955; pp.50-53] Braille Transcription and Mechanical Translation John P. ... the dictionary and precedes "one". "Oner" may be contracted in two ways - "one r" and "o n er. "In the first case "one" is a two -cell contraction...
Ngày tải lên: 16/03/2014, 19:20