manage it as a business
... Manage IT as a Business How to Achieve Alignment and Add Value to the Company This page intentionally left blank Manage IT as a Business How to Achieve Alignment and Add Value to the Company ... Project Analysis 100 Alignment of IT and the Business 100 Manage Risk 101 Examples 103 Lessons Learned 104 Performance Measures for Risk and Project Management Summary 105 Chapter Manage the IT Staff ... technology—Management Information technology––Economic aspects I Larssen, Lee II Title HD 30. 2.L54 200 4 00 4Ј .06 8Ј4—dc22 200 400 5623 British Library Cataloguing-in-Publication Data A catalogue record...
Ngày tải lên: 01/06/2014, 09:20
... 0) and condensation ( m phase < 0) is assumed Where m phase is mass transfer: for evaporation & & & & ( m phase = mevap ) and for condensation ( m phase = mcond ) (kg/s) So that the mass balance ... The values of the electrochemical transport parameters for the base case operating conditions are taken from ref [ 10] and are listed in Table The geometric and the base case operating conditions ... The gas phase and the liquid phase are assumed to be in thermodynamic equilibrium, i.e., the liquid water and the gas phase are at the same temperature The potential distribution in the gas diffusion...
Ngày tải lên: 05/09/2013, 14:58
Module 7: Microsoft Proxy Server 2.0 as a Solution for Internet Connectivity
... Network Load Balancing provides a greater benefit than round robin DNS entries because Network Load Balancing automatically excludes servers that are unavailable You can enhance the availability for ... scenario and answer the questions Be prepared to discuss your answers with the class Scenario A legal firm specializes in patent and copyright law At each geographic location, legal assistants within ... Server as LAN interfaces are persistent, and the data rate is determined by the LAN technology Public network segments that appear as demand-dial interfaces are nonpersistent, and the data rate...
Ngày tải lên: 18/10/2013, 18:15
Tài liệu The Value of the Case Study as a Research Strategy doc
... that the application of the methodology is as likely (perhaps inherently) at fault as the methodology itself Qualitative research as preparation - As mentioned above, qualitative research has a ... research, but many would contend, as Matthew Miles (1979) did in an Administrative Science Quarterly article titled 'Qualitative data as an attractive nuisance' that research based upon case ... real value to qualitative, case-based research This essay has described the case study and its most common manifestations and applications, has briefly discussed the process of preparation, and...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: The hyperfluidization of mammalian cell membranes acts as a signal to initiate the heat shock protein response pptx
... 272 ( 200 5) 607 7– 608 6 ª 200 5 The Authors Journal compilation ª 200 5 FEBS G Balogh et al activity of luciferase expressed in HeLa cells as in [ 20] The cells were incubated at 37 °C with 30 mm BA or ... or at 42 °C for 30 Immediately after treatment, the cells were cooled to °C and lysed Luciferase activity was measured as described in [48] Statistical analysis All data are expressed as mean ... Foundation (OTKA: TS 04 4836, T 03 8334) and Agency for Research Fund Management and Research Exploitation (RET OMFB 000 67 ⁄ 200 5 and Bio -00 1 20 ⁄ 200 3 KPI) References Pockley GA ( 200 1) Heat shock proteins...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx
... Journal 276 ( 200 9) 605 0– 606 2 ª 200 9 The Authors Journal compilation ª 200 9 FEBS 605 9 BIM as a mediator of tumour cell death A S Gillings et al 20 Luciano F, Jacquel A, Colosetti P, Herrant M, Cagnol ... 17657–17663 30 Haber DA & Settleman J ( 200 7) Cancer: drivers and passengers Nature 446, 145–146 31 Hanahan D & Weinberg RA ( 200 0) The hallmarks of cancer Cell 100 , 57– 70 32 Weinstein IB & Joe A ( 200 8) ... Journal 276 ( 200 9) 605 0– 606 2 ª 200 9 The Authors Journal compilation ª 200 9 FEBS 605 3 BIM as a mediator of tumour cell death A S Gillings et al for the MEK1 ⁄ 2–ERK1 ⁄ pathway and show similar oral...
Ngày tải lên: 16/03/2014, 00:20
Love Your Work, Love Your Life: Make it Happen as a Freelance Translator pot
... assuming that the average translator translates 1 ,00 0 to 3 ,00 0 words in an average 8-hour day If it is not feasible, you must help the client understand that no translator will be able to complete ... language classes? Most translators recognize that the ability to work with languages is special – it s a gift, an art, a craft It s not surprising that many of them also teach language skills ... the translation market for you Chapter 4.5: Should I learn additional languages? Researchers believe that language acquisition is a natural phenomenon That is, our brains pick up language without...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: Coenzyme A affects firefly luciferase luminescence because it acts as a substrate and not as an allosteric effector pot
... intensity was attained (12 s) the formation of the inhibitory product antagonized by CoA has only began and the effect of CoA at that assay time was nil or a discrete activation (always less than ... preincubating it with ATP, acetate, MgCl2, acetyl-CoA synthetase and inorganic pyrophosphatase (PPase) Then, we conrmed that treated acetyl-CoA was no longer antagonist of L-AMP in bioluminescent reactions ... luciferin, amino acid, and fatty acid utilization are compared Science 157, 1 501 60 Suzuki H, Kawarabayasi Y, Kondo J, Abe T, Nishikawa K, Kimura S, Hashimoto T & Yamamoto T (19 90) Structure and regulation...
Ngày tải lên: 16/03/2014, 23:20
Báo cáo khoa học: RIP1 comes back to life as a cell death regulator in TNFR1 signaling docx
... factor-kappaB and interferon regulatory factor signaling pathways Nat Immunol 8, 592– 600 73 Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M & Sasakawa C ( 201 0) A bacterial E3 ubiquitin ligase ... NF-kappaB activation [corrected] Nat Cell Biol 8, 398– 406 Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S et al ( 200 9) Involvement of linear ... early after receptor ligation whereas the cell death regulators FAS-associated via death domain (FADD) and caspase are recruited to a pro-apoptotic complex that forms slowly in the cytoplasm This...
Ngày tải lên: 28/03/2014, 23:20
báo cáo hóa học:" Combined intermittent hypoxia and surface muscle electrostimulation as a method to increase peripheral blood progenitor cell concentration" pot
... 6 .06 44.1 10. 03 43.3 6.71 0. 064 0. 014 0. 025 0. 017 0. 0 50 0 .01 3 0. 063 0. 017 0. 0 40 0 .00 8 0. 0 40 0 .01 0 0. 061 0. 012 0. 0 50 0 .01 9 0. 055 0. 017 0. 0 50 0 .02 6 0. 0 70 0 .03 6 0. 035 0. 019 0. 075 0. 023 0. 100 0. 0 30 ... Physiol 200 8, 103 : 203 -213 Rodriguez FA, Ventura JL, Casas M, Casas H, Pages T, Rama R, Ricart A, Palacios L, Viscor G: Erythropoietin acute reaction and haematological adaptations to short, intermittent ... and/or assembly of data, data analysis and interpretation, manuscript writing; RS: data analysis and interpretation, manuscript writing All authors read and approved the final manuscript Additional...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " A pilot clinical trial testing mutant von HippelLindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma" doc
... mutation HLA -A HLA-B HLA-DR del TT 443-444 148 Phe-Cys fsX25 02 15, 40 04, 13 HLA-DQ 03 , 06 T-C 497 G-T 332 166 Val-Ala 111 Ser-Ile 02 ,11 03 , 29 3 701 , 400 1 14, 35 100 1, 13 01 , 13 05 01, 06 05 , 06 ... Cincinnati, OH, Cat#33 10- 10) was added to each well for hour followed by manual washes Finally, The BCIP/NPT substrate, 100 ul/well, (KPL, Gaithersburg, Maryland, Cat# 50- 81 -08 ) was added and the ... Metastatic renal -cell carcinoma: what causes occasional dramatic regressions? N Engl J Med 1998, 338:1 305 -1 306 Kirchner HH, Anton P, Atzpodien J: Adjuvant treatment of locally advanced renal cancer...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc
... type diabetes subjects Immunogenetics 201 0, 62: 101 - 107 36 Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, et al: Genetic association ... receptor alpha chain deficiency Pediatr Res 200 0, 48:6-11 19 Bernasconi A, Marino R, Ribas A, Rossi J, Ciaccio M, Oleastro M, Ornani A, Paz R, Rivarola MA, Zelazko M, Belgorosky A: Characterization ... Heterogeneity of natural Foxp3+ T cells: a committed regulatory T -cell lineage and an uncommitted minor population retaining plasticity Proc Natl Acad Sci USA 200 9, 106 :1 903 -1 908 55 Lu LF, Thai TH, Calado...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo sinh học: "Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma" doc
... tumorigenicity of renal cell carcinoma through induction of apoptosis Cancer Gene Ther 201 0, 17:212-222 Morikawa T, Sugiyama A, Kume H, Ota S, Kashima T, Tomita K, Kitamura T, Kodama T, Fukayama M, Aburatani ... physic-chemical properties (size and charge) of each separate material, including PCFC-g-PEI and FA-PEAs, as well as the FA-PEAs: pVHL complexes Because PCFC-g-PEI and FA-PEAs are amphiphilic ... derivatives was primary evaluated in OS-RC-2 cell line Compared with 25-kD PEI, 10, 20 and 30 μg/ml PCFC-g-PEI had no apparent cytotoxicity on cells While the cell survival rate was approximately...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma" pot
... tumorigenicity of renal cell carcinoma through induction of apoptosis Cancer Gene Ther 201 0, 17:212-222 Morikawa T, Sugiyama A, Kume H, Ota S, Kashima T, Tomita K, Kitamura T, Kodama T, Fukayama M, Aburatani ... physic-chemical properties (size and charge) of each separate material, including PCFC-g-PEI and FA-PEAs, as well as the FA-PEAs: pVHL complexes Because PCFC-g-PEI and FA-PEAs are amphiphilic ... derivatives was primary evaluated in OS-RC-2 cell line Compared with 25-kD PEI, 10, 20 and 30 μg/ml PCFC-g-PEI had no apparent cytotoxicity on cells While the cell survival rate was approximately...
Ngày tải lên: 20/06/2014, 03:20
Cell Membrane: The Red Blood Cell as a Model ppt
... Shibata, Drs Osamu Yamada, Atsushi Togawa, Shunsuke Koresawa, Sumire Hasegawa, Yoshinobu Takemoto, Masahiro Yoshimoto, Kazuyuki Mitani, Kosuke Miyashima, Masakiyo Mannoji, Takashi Sugihara, Nobumasa ... Nobumasa Inoue, Masaoo Shimoda, Akio Kanzaki, Masashi Hashimoto, Hiroo Mori, Takemi Otsuki, Kazuyuki Ata, Hideho Wada, Akiyo Otsuka (Ikeda), Lisa Shirato, the late Kimiko Ikoma, Takafumi Inoue, Naoto ... Mayumi Aizawa (Takahara), Chie Kawasaki and Sakura Eda Kawasaki Medical School (Research Center for Electron Microscopy): Mr Kenzo Uehira and Taiji Suda Kawasaki Medical School (Secretarial works):...
Ngày tải lên: 29/06/2014, 11:20
Báo cáo sinh học: "Generalized immune activation as a direct result of activated CD4+ T cell killing" doc
... (x 10- 6) Mphi T cells B cells IFN-γ (d) CD4:CD8 ratio 0. 000 1 0. 000 1 0. 04 0. 04 0. 000 2 0. 000 2 0. 02 0. 02 0. 01 0. 01 0. 01 0. 01 0. 002 0. 002 0. 2 MCP-1 1cm cm 0. 4 WT DTA MIP-1α SP DTA Total cells 0. 6 ... by Kim Hasenkrug, Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, USA) was free of lactate dehydrogenase-elevating virus and was obtained as previously ... FoxP3 20 10 0 .00 47 0. 20 0 .00 MCP-1 0. 033 0. 50 11 CD45.1 0. 2 10 DTA host WT host 0. 2 15 % of CD8+ T cells Serum cytokine levels (ng/ml) 0. 005 3 % of CD8+ T cells in blood Donor cells (% of CD4+ T cells)...
Ngày tải lên: 06/08/2014, 19:21
Báo cáo sinh học: "The THO complex as a key mRNP biogenesis factor in development and cell differentiation" potx
... (phosphorylation, ubiquitination, and so on) that might change its pattern of activity Acknowledgements We thank R Luna and AG Rondón for critical reading of the manuscript The work of AA’s laboratory is funded ... Spanish Ministry of Innovation and Junta de Andaluc a Published: 28 January 201 0 Page of References Aguilera A: Cotranscriptional mRNP assembly: from the DNA to the nuclear pore Curr Opin Cell ... essential for hematopoietic primitive cell survival in vivo BMC Biol 201 0, 8:1 Huertas P, Garc a- Rubio ML, Wellinger RE, Luna R and Aguilera A: An hpr1 point mutation that impairs transcription and...
Ngày tải lên: 06/08/2014, 19:21
Báo cáo khoa học: "Solitary colonic metastasis from renal cell carcinoma presenting as a surgical emergency nine years post-nephrectomy" pot
... metastasis of renal cell carcinoma seven years after nephrectomy: a case report Int J Urol 1996, 3(6): 501 -3 Uchida K, Miyao N, Masumori N, Takahashi A, Oda T, Yanase M, Kitamura H, Itoh N, Sato ... Unusual metastases Indian J Radiol Imaging 200 0, 10: 249-51 Tanis PJ, van der Gaag NA, Busch OR, van Gulik TM, Gouma DJ: Systematic review of pancreatic surgery for metastatic renal cell carcinoma ... from renal cell carcinoma: helical-CT demonstration Eur Radiol 200 0, 10( 1):139- 40 Utsunomiya K, Yamamoto H, Koiwai H, Kirii Y, Kashiwagi H, Konishi F, Kurihara K, Kawai T, Sugano K: Solitary colonic...
Ngày tải lên: 09/08/2014, 03:21