cdc—oversight of high risk grantees

... identified critical structures (normal tissue avoidance paradigm) in the setting of hypofractionated treatment of high- risk prostate cancer Helical tomotherapy will be used as the dynamic intensity ... pelvic soft tissue target volume looks specifically at the soft tissues within the pelvic field that excludes the nodal target and the organs at risk (Table 6) Given the highly conformal nature of ... delivery and critical structure sparing in the setting of hypofractionation for high- risk prostate cancer This technical dosimetric feasibility study offers evidence that conformal avoidance, as an...

Ngày tải lên: 09/08/2014, 10:21

... frequency of the high- risk group is lower than, equal to or higher than the disease risk The frequency of the high- risk group is defined as the proportion of individuals with a number of risk alleles ... different frequencies of the population at high risk The frequency of the population at high risk is defined as the proportion of individuals with a number of risk alleles equal to or higher than the ... possible thresholds of the genetic risk scores When a higher threshold is used, the population at high risk has a higher risk (higher PPV), but this will identify a smaller percentage of the affected...

Ngày tải lên: 11/08/2014, 12:21

... as a result of a high probability of perioperative myocardial ischaemia This usually accounts for between 10% and 20% of the total population of high- risk patients Ideally, this form of management ... care for the high- risk patient A practical approach to perioperative care for the high- risk patient The first step in the care of such patients is to identify the individual at risk (Fig 1) It ... prove to be useful in highrisk surgery [27] The use of inodilator agents, for example dopexamine, with modest maximum infusion rates may minimize the risk for complications of inotrope use These...

Ngày tải lên: 12/08/2014, 20:20

... trial of supranormal values of survivors as therapeutic goals in high- risk surgical patients Chest 1988, 94: 1176-1186 Boyd O, Grounds RM, Bennett ED: A randomized clinical trial of the effect of ... increase of oxygen delivery on mortality in high- risk surgical patients J Am Med Assoc 1993, 270:2699-2707 Wilson J, Woods I, Fawcett J, Whall R, Dibb W, Morris C, McManus E: Reducing the risk of major ... target value of 600 ml/min/m2, initially with intravenous colloid and then with the addition of dopexamine at a dose no higher than µg/kg/min The target value is not reached in a minority of patients,...

Ngày tải lên: 12/08/2014, 23:22

... chance of surviving [6,7] Also, identification of high- risk groups of patients may be useful for risk stratification in scientific trials or for comparing outcomes of different ICUs The aim of our ... II model would lead to a higher PPV for identifying high- risk patients In the complete validation database, 112 (4.9%) of the patients had a predicted risk of mortality of more than 80% in both ... with a GCS score of less than had a risk of 89.2% (Figure 1) Of all Page of (page number not for citation purposes) Critical Care Vol 11 No de Rooij et al Table Characteristics of patients surviving...

Ngày tải lên: 13/08/2014, 03:20

... re-offenders/one-time offenders d =difference between re-offenders and one-time offenders Table Offence characteristics of childhood one-time offenders and re-offenders One-time offenders Re-offenders ... type of first offence and seriousness of first offence between one-time offenders and re-offenders Re-offenders were slightly older at their first arrest and less often committed their offence ... peers Studies focusing on risk factors of officially registered childhood offenders remain scarce and studies examining the risk factors of registered re-offending childhood offenders are even scarcer...

Ngày tải lên: 13/08/2014, 18:22

... knowledge base and professional dental guidelines regarding topical fluoride use with high- risk children n Reviewing the concept of risk and defining high- risk children n Identifying risk factors and ... should be included in the high- risk category In defining the category of high- risk children, the group questioned whether the high- risk category was in the context of a two-tier Guiding Questions ... professionals and programs working with young high- risk children as to the recommended use of topical fluoride, weighing the caries-preventive benefits of fluoride with the potential risk of...

Ngày tải lên: 12/02/2014, 19:20

... look resections of high risk patients and if the improvement in the rate of detection of flat lesions in the follow-up may improve the use of additional treatment and the prognosis of these patients ... follow-up of high risk patients Author details Department of Urology, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy 2Department of Clinical Pathology, Desio Hospital, University of ... as well as the therapeutic effect of immunoprophylaxis in these high risk patients Because bladder cancer is often multicentric, particularly when it is of high grade, a standard WL resection...

Ngày tải lên: 18/06/2014, 16:20

... from several high risk HPV types and further, to compare E6-mediated ubiquitination of p53 and MAGI-3 The results of this study provide a better understanding about the interactions of viral E6 ... an increased risk of high- grade disease although studies involving larger populations of HPV-33 carriers are needed to confirm this [27] We also compared E6-mediated degradation of p53 and MAGI-3 ... p53 degradation in transfected cell lines [26] The fusion of GFP to the N-terminal of E6 therefore enabled the detection of E6-GFP by immunofluoresence and Western blot analysis using anti-GFP antibodies...

Ngày tải lên: 20/06/2014, 01:20

... evaluation of CRP in the setting of acute evaluation, did not utilize a high- sensitivity assay Prior studies evaluating the use of CRP in the acute setting vary with the risk of disease, length of follow-up, ... events was 1.0 mg/l to 3.0 mg/l and high risk >3.0 mg/l Page of Statistical analysis Hs-CRP threshold We evaluated the thresholds for intermediate risk and high risk based on manufacturer recommendations ... subgroup of 191 ED patients with an inconclusive cause of chest pain and determined the diagnostic value of a change in two measurements of hs-CRP In the cohort of 191 patients, 38 had a diagnosis of...

Ngày tải lên: 21/06/2014, 02:20

... and one of leading causes of diseases worldwide These viruses have shared modes of transmission but the transmission efficiency of each virus differs from each other Persons at high risk for ... the selection of ART by increasing the risk of drug-related hepatoxicity and of specific agents Owing to characteristics of disease transmission like that those agents has very high potentially ... one's also have risk of HCV infection Result of our study showed that the rate of HCV infection during 2008-2010 (60.0%, 57.3%, 69.3%, respectively) was higher than the rate of HIV infection...

Ngày tải lên: 25/07/2014, 14:07

... Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra -high risk of psychotic disorder Shigenori Tadokoro1,2,*, Nobuhisa Kanahara1, ... patients at ultra -high risk (UHR) of psychotic disorder, from transitioning to psychosis However, the mechanism of such an effect is still unknown Methods: We report the case of a 19-year-old ... Masaomi Iyo1,3 Department of Psychiatry, Chiba University Graduate School of Medicine, Chiba, Japan Department of Psychiatry, Sodegaura Satsukidai Hospital, Chiba, Japan Division of Clinical Neuroscience,...

Ngày tải lên: 09/08/2014, 01:21

... M:F) with high- risk cutaneous SCC underwent SLN biopsy (mean age = 72 years, range 5189 years) All patients had at least two previously described high- risk factors, two patients had high- risk factors, ... other hand, SLN biopsy for patients with high- risk lesions of the trunk and extremities (N = 49) had a noticeably lower NPV of 95.2% Two patients in this high- risk group developed recurrent nodal ... This study and review of literature highlights the potential limitations of SLN biopsy for SCC and the critical importance of careful long-term follow-up in these high- risk patients Though cytokeratin...

Ngày tải lên: 09/08/2014, 02:20

... All of the prospective studies made attempts to identify subgroups of patients at higher risk for recurrence In the GOG study [11], a "high intermediate" group was defined by a combination of risk ... the higher risk group had a 13% risk for local-regional failure The high intermediate risk patients were also at risk for failing distantly, with a 48-month observed distant failure rate of 19% ... to high tumor grade As the first site of failure, the control arm of the low intermediate risk group (which comprised approximately two thirds of the patients) had an observed failure rate of...

Ngày tải lên: 09/08/2014, 10:21

... Hospitalisations may be avoidable by coordinated and structured chronic care Many of the high- risk patients suffering from any of these index conditions will have additional co-morbidities [18,19] Complex ... components of care management interventions Key components of care management interventions as proposed by Bodenheimer and Berry-Millet [10] Page of management intervention for patients with any of these ... potential role of HCAs in chronic care is scarce Our overall aim of reducing avoidable hospitalizations by introducing a HCA-led care management intervention targeting patients at high risk for future...

Ngày tải lên: 10/08/2014, 10:23

... Age Age of first sexual intercourse Age of initiation of addiction Risk behavior for hepatitis C Paid for sex: Yes No Age Age of first sexual intercourse Age of initiation of addiction Risky behavior ... Age Age of first sexual intercourse Age of initiation of addiction used a condom There was significant difference between the average age of study participants, average age of initiation of drugs ... Conclusion The entrance of the HIV virus in this high risk groups requires prudent measures of risk, harm reduction and rehabilitation Immediate efforts are required for development of proper rehabilitation...

Ngày tải lên: 11/08/2014, 18:20

... at very high risk of blood-borne infections A range of interlinking factors compound this risk – the large number of IDUs, scarcity of sterile injecting equipment and correspondingly higher prevalence ... suggest that mobile van outlets of NSPs are effective in reaching hidden and high- risk group of IDUs A large study (n = 1020) in Vancouver compared risk taking behaviours of IDUs attending conventional, ... of whom 59% were without medical follow-up Complementary or duplication of services? As evidence for the ability of these two types of NSP outlets to reach the hidden, hard-to-rich and high- risk...

Ngày tải lên: 11/08/2014, 18:20

... progression of cervical cancer Additionally, establishment of a role of cell fusion in carcinogenesis of cervical cancer is of reference value for understanding the pathogenesis of other virus-associated ... mechanisms of high- risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins Cancer Sci 2007, 98:1505-1511 Tsai TC, Chen SL: The biochemical and biological functions of human ... that high- risk HPV E5-induced cell fusion may play a critical role in the early stage of HPV-associated cervical cancer However, it is widely accepted that increasingly deregulated expression of...

Ngày tải lên: 12/08/2014, 01:21

... vertical transmission of this virus, and to assess any associated risk factors Table Demographic profile of women with cervical cancer Results Age range Demographic profile of women with cervical ... presence of HPV in the anal region and the oral cavity of Danish children, aged to 17 years, by PCR targeting the L1 region of the HPV genome Only four of the 249 anal samples and one of 392 oral ... that there is low, if any, risk of HRHPV infection in oral cavity of women with cervical cancer There were no relevant risk factors that contributed to the development of this infection Further,...

Ngày tải lên: 12/08/2014, 04:20