cd4 t cells and mds

Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

... potentially relevant articles to determine whether an article met the inclusion criteria, and disagreement was resolved by discussion between the investigators Data extraction We abstracted the ... scanned titles and abstracts for mention of GST polymorphisms associated with cancer outcome in either the title or the abstract We retrieved 121 potentially eligible articles in full text [Figure ... article (citations per year) 494 Statistical analysis Associations were tested using the chi-square statistic or Fisher’s exact test with significance set at P < 0.05 The null hypothesis is that...

Ngày tải lên: 25/10/2012, 10:51

9 524 0
How can we speak math?

How can we speak math?

... [better] Extensions You may not be entirely comfortable with the limited vocabulary, and prefer other words and phrases These should also be allowed, certainly to the extent that they not interfere ... a totally new notation makes it logically impossible to properly encode it with respect to its (up to this moment undefined) semantics A kind of meta-language relating both new notation and the ... input model is that the computer system can display what has been recognized so far The longest delay is likely to be the pause while the computer waits to determine the end of the utterance The...

Ngày tải lên: 26/10/2013, 19:15

20 600 0
What is the neutral real interest rate, and how can we use it? doc

What is the neutral real interest rate, and how can we use it? doc

... state growth rate of output and the real interest rate, they not imply that one can take the steady state growth rate of output as a direct estimate of the long run equilibrium real interest ... distinction and clarify between actual and potential output is known as the “output alternative concepts of the neutral real interest rate We gap” If actual output is greater than potential output ... interest rate takes us closer to is neutral over the medium run, and what real interest rate is the actual policy setting in that it takes account of current neutral at the current point in time,...

Ngày tải lên: 15/03/2014, 01:20

14 540 0
Central Bank Credit to the Government: What Can We Learn from International Practices? pdf

Central Bank Credit to the Government: What Can We Learn from International Practices? pdf

... to the State 16.1 The National Bank shall not loan to the state directly for the purposes of funding the state budget deficit 16.2 In the event of a short-term liquidity shortfall in the state ... necessity to cover debt commitment on the targeted loan through state guarantee and in the event of full or partial coverage of this commitment through debt securities issued by the State, at the ... the same treatment by national central banks and the ECB as private credit institutions Title: Protocol (No 18) on the Statute of the European System of Central banks and of the European Central...

Ngày tải lên: 22/03/2014, 21:20

44 411 0
Báo cáo khoa học: "How Much Can We Gain from Supervised Word Alignment" potx

Báo cáo khoa học: "How Much Can We Gain from Supervised Word Alignment" potx

... (trained with billion words) in our experiments further alleviated the impact of incorrect translation rules Fourth, the GALE test set has fewer reference translations than the NIST test sets ... alignment We aligned Chinese word s to English word t if and only if s contains a character c that was aligned to t in the LDC annotation A unique feature of the LDC annotation is that it contains ... translations for both sets The tuning metric was BLEU, but we reported results in BLEU (Papineni et al., 2002) and TER (Snover et al., 2006) 2.2 they cannot be effectively exploited by the translation model...

Ngày tải lên: 23/03/2014, 16:20

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báo cáo hóa học: " Can we derive an ''''exchange rate'''' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique" doc

báo cáo hóa học: " Can we derive an ''''exchange rate'''' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique" doc

... and interpretation of results, and drafted the manuscript LS participated in the design of the study and interpretation of results, and suggested edits and revisions to the manuscript JS contributed ... contributed to the acquisition and interpretation of the data, participated in the interpretation of results, and suggested edits and revisions to the manuscript All authors read and approved the ... with respect to other criteria, such precision might not be necessary for the sort of between-group comparisons that form the basis for estimates of both treatment effects and health-state utilities...

Ngày tải lên: 18/06/2014, 18:20

19 478 0
báo cáo hóa học: " Can we make the basilic vein larger? maneuvers to facilitate ultrasound guided peripheral intravenous access: a prospective cross-sectional study" ppt

báo cáo hóa học: " Can we make the basilic vein larger? maneuvers to facilitate ultrasound guided peripheral intravenous access: a prospective cross-sectional study" ppt

... practical in the ED setting While temperature was not directly accounted for in this study, we not believe that it functioned as a confounder since all of the subjects served as their own controls ... a tourniquet with the arm resting below the level of the heart Future investigation of these maneuvers designed to facilitate USGPIV should study patients with failed landmark IV techniques, ... involved in the study design, statistical analysis, and manuscript preparation GM and LM were involved in the study design and carrying out study measurements HW provided statistical support and was...

Ngày tải lên: 21/06/2014, 00:20

5 421 0
Curcumin for monoclonal gammopathies  what can we hope for, what should we fear

Curcumin for monoclonal gammopathies what can we hope for, what should we fear

... inflammation Down-regulates interleukin-6 an inflammatory cytokine that inhibits the maturation of dendritic cells by activation of the STAT3 pathway Inhibits the STAT3 pathway which is activated ... maturation thereby contributing to the immune tolerance of cancer [48] [51] Tumor cells appear able to convert DCs into cells that secrete bioactive TGF-beta and stimulate proliferation of Tregs These ... similar to those present in the intestine Curcumin treated DCs are not only immature, they are also maturation resistant This means that curcumin treated DCs not mature under inflammatory conditions...

Ngày tải lên: 01/07/2014, 13:22

11 488 0
Can we do better than Agrobacterium ? pdf

Can we do better than Agrobacterium ? pdf

... (4), lý t bào ph t triển thành khối u (hay n t sần) Đầu thập kỷ 80 coi "thời đại hoàng kim" chuyển gen Agrobacterium người ta ph t rằng: - T- DNA, đoạn Ti plasmid, t o khối u thực v t ph t triển ... Agrobaterium lời t c giả thừa nhận Điều khiến người ta đ t câu hỏi liệu chủng có th t khác bi t với Agrobacterium, đặc bi t tranh cãi m t phân loại thu t ngữ Do vậy, dường "an toàn" t p trung ... Vùng vir T- DNA nằm vector vector riêng bi t - T- DNA chuyển vào t bào mô thực v t sau gắn vào genome thực v t - Gene chuyển biểu t bào thực v t - Các t bào mô chuyển gene t i sinh thành hoàn...

Ngày tải lên: 02/07/2014, 11:21

16 192 0
Báo cáo sinh học : "What do we know about influenza and what can we do about it" ppsx

Báo cáo sinh học : "What do we know about influenza and what can we do about it" ppsx

... reflects both the characteristics of the infecting virus and host factors Important host factors include age, basic health status and prior exposure to the same or related viruses, with the very ... vaccine must be produced The most efficient, in terms of the amount of product required, are the so-called live-attenuated vaccines that have been adapted to replicate poorly so that they not cause ... replication has the advantage that it can be used at lower titer, but the disadvantage that its safety is less secure than that of a killed one For this reason, such vaccines are not currently recommended...

Ngày tải lên: 06/08/2014, 19:20

4 325 0
Báo cáo lâm nghiệp: "Can we reconstruct deer browsing history and how? Lessons from Gaultheria shallon Pursh" pdf

Báo cáo lâm nghiệp: "Can we reconstruct deer browsing history and how? Lessons from Gaultheria shallon Pursh" pdf

... first leaves between deer-free and deeraffected sites with a t- test We also plotted the distribution of the height of the first leaves We compared mean age and mean stem height with a nested ... series and validated by a Student t- test 2.3.2.1 Age determination We selected the area of the cross-section that was most legible We pointed rings for each cross-section and counted them along two ... cambial activity starts at the tip of the stem, easily identifiable growth rings are restricted to the upper part of a stem, whereas very narrow rings characterise the lower part of a stem This causes...

Ngày tải lên: 08/08/2014, 00:21

10 374 0
Báo cáo y học: " MAPK signalling in rheumatoid joint destruction: can we unravel the puzzle? " pps

Báo cáo y học: " MAPK signalling in rheumatoid joint destruction: can we unravel the puzzle? " pps

... mice In the light of this and previous data, it seems that there is only a narrow window of time in which anti-TNF-α treatment can entirely prevent the onset of arthritis and the activation of ... destructive joint disease in the hTNFtg mouse model of RA [7] The data seem to contradict the aforementioned results in rat adjuvant arthritis [2], but given the multitude of data on JNK activation in ... that chronic destructive arthritis does not require JNK activation This notion is supported by other recent data of Georg Schett’s group demonstrating that JNK1 is not required for destructive...

Ngày tải lên: 09/08/2014, 07:20

2 309 0
Báo cáo y học: "How can we reduce the risk of serious infection for patients with systemic lupus erythematosus" ppt

Báo cáo y học: "How can we reduce the risk of serious infection for patients with systemic lupus erythematosus" ppt

... disease drugs as standard of care for all patients with SLE without contraindications Competing interests The author declares that they have no competing interests References Anti-malarials have ... patients with rheumatoid arthritis but similar guidelines have not been developed for SLE With the exception of the live attenuated vaccines, other vaccinations should be kept up-to-date in patients ... mechanism of action in that they interfere with antigen processing by raising lysosomal pH and may prevent apoptotic debris from stimulating and sustaining autoimmunity through inhibition of toll-like...

Ngày tải lên: 09/08/2014, 14:22

2 339 0
báo cáo khoa học: "How can we improve guideline use? A conceptual framework of implementability" pps

báo cáo khoa học: "How can we improve guideline use? A conceptual framework of implementability" pps

... implementability elements This is a method that describes explicit content as reported in written, verbal, or visual communication qualitatively and/ or quantitatively, without interpretation of its underlying ... of this study and data interpretation VAP assisted with design of this study, independently reviewed data extracted from guidelines, and assisted with interpretation All co-investigators contributed ... manuscript for publication; and who will take no part in the collection, analysis and interpretation of data; or writing of subsequent manuscripts Author details Departments of Surgery; and Department...

Ngày tải lên: 10/08/2014, 10:23

11 345 0
báo cáo khoa học: " Prostate cancer genomics: can we distinguish between indolent and fatal disease using genetic markers?" docx

báo cáo khoa học: " Prostate cancer genomics: can we distinguish between indolent and fatal disease using genetic markers?" docx

... variants together explain approximately 22% of the familial risk of prostate cancer, and it is anticipated that many more prostate cancer susceptibility variants will be identified in the future ... Swedish patients with prostate cancer explored the association between 16 established risk variants and prostate cancer mortality [52] In total, 2,875 patients diagnosed between 2001 and 2003 ... informative at an earlier stage when the disease is potentially curable However, it is evident that hitherto identified prostate cancer risk variants provide little or no discriminative capacity between...

Ngày tải lên: 11/08/2014, 12:20

7 242 0
báo cáo khoa học: " Can we prevent drug related deaths by training opioid users to recognise and manage overdoses?" doc

báo cáo khoa học: " Can we prevent drug related deaths by training opioid users to recognise and manage overdoses?" doc

... clients (87.0%) reported that they still had the naloxone that they were given at the end of the training session Of the remaining, reported that they had lost it and were not sure At the six-month ... their treatment worker when they stopped using heroin, and one had thrown it away when they started inpatient detoxification treatment The data for the other two cases were missing However, of the ... trained still possessed the naloxone six months later suggesting a commitment to the process of peer education and intervention It is intriguing to note that knowledge reported at the end of the training...

Ngày tải lên: 11/08/2014, 18:20

8 260 0
Báo cáo khoa học: " Blood management in intensive care medicine: CRIT and ABC — what can we learn" docx

Báo cáo khoa học: " Blood management in intensive care medicine: CRIT and ABC — what can we learn" docx

... outcome is not due to a harmful effect of allogeneic RBC transfusion in itself, but merely reflects the fact that transfused patients were sicker to start with Indeed, there is some evidence that ... observational Therefore, despite the finest statistical models used showing that allogeneic blood transfusions were independently associated with a higher mortality [1,2], it remains possible that this ... unchanged and the effect on mortality was borderline [8] No in-depth information regarding the type of RBCs transfused and the effect of transfusion on outcome are available in the CRIT and ABC studies,...

Ngày tải lên: 12/08/2014, 20:20

3 240 0
Báo cáo khoa học: " Understanding the lingering consequences of what we treat and what we do" potx

Báo cáo khoa học: " Understanding the lingering consequences of what we treat and what we do" potx

... capability domino into impaired mental and mood status? Which ICU patient groups are most susceptible to any of these events, and who is most susceptible to the entire chain of events? Similar questions ... GM61992) to determine intermediate and long-term outcomes of critical illness References So how we tease this out? Fundamentally, we have to begin articulating and testing specific hypotheses about ... future investigations that will hopefully interrogate further the potential mechanisms of action that underlie poor longterm outcomes In the meantime, we can hope that this quality of follow-up...

Ngày tải lên: 12/08/2014, 20:20

2 256 0
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