carotenoid packaging into chylomicrons in the intestine

Báo cáo khoa học: Gene expression silencing with ‘specific’ small interfering RNA goes beyond specificity – a study of key parameters to take into account in the onset of small interfering RNA off-target effects potx

Báo cáo khoa học: Gene expression silencing with ‘specific’ small interfering RNA goes beyond specificity – a study of key parameters to take into account in the onset of small interfering RNA off-target effects potx

... differences in exposure times during western blotting We also observed a slight increase in SREBF1 protein level triggered in the presence of the NT siRNA, in agreement with the slight increase in SREBF1 ... processes in a cell type-dependent manner For instance, an increase in the cell cycle timing could be expected following the downregulation of PCNA, coding for a protein involved in the control ... The role of sequence pairing in siRNA side effects is also supported by data showing that these effects can be dramatically reduced in the presence of another control, the RNA-induced silencing...

Ngày tải lên: 07/03/2014, 05:20

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development of macrophages in the intestine

development of macrophages in the intestine

... 2013) Intestinal mφ are found in the lamina propria, just underneath the epithelial surface all along the length of the intestinal tract There are more mφ in the colon than the small intestine, ... are found throughout the body, with the single largest population being in the intestine and they act as innate effector cells ingesting and killing microbes, as well as having important homeostatic ... 16 Chapter General introduction 21 1.1 The intestinal immune system 22 1.2 Adaptive immune responses in the intestine 22 1.3 Innate immunity in the intestine 24 1.4 TLRs and...

Ngày tải lên: 22/12/2014, 17:32

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The winds of change an insight into ma in the renewable energy sector in 2009

The winds of change an insight into ma in the renewable energy sector in 2009

... continue to be economically viable Digging down into the detail, the report unearths some interesting insights into where many energy companies are planning to invest their cash in the coming ... percent of respondents say that they envisage their company investing in renewables in the US in the next year, making the country by far the most common choice India, China and Canada are also popular ... drop in M&A activity in the latter half of the year According to NEF, corporate M&A in renewables declined from the first quarter 2008 —with the last three months showing the worst result since the...

Ngày tải lên: 06/12/2015, 23:15

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Báo cáo y học: " Identification of the 15FRFG domain in HIV-1 Gag p6 essential for Vpr packaging into the virion" pdf

Báo cáo y học: " Identification of the 15FRFG domain in HIV-1 Gag p6 essential for Vpr packaging into the virion" pdf

... Vpr packaging in the absence of the (Lxx)4 domain The Pr-(Lxx)-/R+ construct still maintains a 15FRFG domain in p6 which resembles the FxFG domain frequently observed in resident proteins of the ... virion packaging Since FxFG domains also occurs in nuclear pore proteins, the current finding also suggests for the first time that Vpr may recognize the same FxFG domain for both virion packaging ... both the late phase and the early phase of the HIV-1 life cycle To examine the roles of individual amino acid residues in the 15FRFG domain during Vpr packaging, Phe15, Arg16 and Phe17 were individually...

Ngày tải lên: 13/08/2014, 13:20

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An investigation into group work activities in the 10th graders' english speaking classes at quy hop II high school in nghe an province

An investigation into group work activities in the 10th graders' english speaking classes at quy hop II high school in nghe an province

... language teaching in particular are not the changes in the way we teach These are the changes in the aims of language teaching and learning In Viet Nam, The Ministry of Education and Training has recently ... asking questions, explaining, making suggestion, criticizing, listening , agreeing , disagreeing or making joint decisions, but also this may be nonverbal such as pointing, showing how, nodding, ... using group activities in their teaching speaking skill and have been trying to use them in their teaching In observation process, in addition, the researcher saw that most of English speaking...

Ngày tải lên: 18/12/2013, 10:08

110 1,1K 6
Tài liệu Integrating gender into HIV/AIDS programmes in the health sector ppt

Tài liệu Integrating gender into HIV/AIDS programmes in the health sector ppt

... understanding of the basic concepts of gender mainstreaming, and the ways in which these are linked to health and HIV, there is the goal of increasing understanding of these concepts On the other ... stakeholders was the identification of entry points for systematically integrating or mainstreaming gender into the implementation of the National AIDS Control Programme This included, for example, the national ... Integrating gender into HIV/AIDS programmes in the health sector Tool to improve responsiveness to women’s needs WHO Library Cataloguing -in- Publication Data Integrating gender into HIV/AIDS...

Ngày tải lên: 13/02/2014, 00:20

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Tài liệu University Oars Being a Critical Enquiry Into the After Health of the Men Who Rowed in the Oxford and Cambridge Boat-Race, from the Year 1829 to 1869, Based on the Personal Experience of the Rowers Themselves pdf

Tài liệu University Oars Being a Critical Enquiry Into the After Health of the Men Who Rowed in the Oxford and Cambridge Boat-Race, from the Year 1829 to 1869, Based on the Personal Experience of the Rowers Themselves pdf

... health; in others, to the rowers being by nature constitutionally delicate; and in others again, to their having thoroughly overdone it, to their being in boating language "stale." As regards the ... rowing as to be of little or no service in maintaining the theory of rowing being injurious to the health At the same time I have never doubted that his early death, at the age of twenty-nine, ... of his indisposition (but once when living in damp air) If the induration of the right lung which was observed in A.'s case really commenced at the time he experienced pain in rowing in the College...

Ngày tải lên: 14/02/2014, 21:20

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Tài liệu Fashioning Archaeology into Art: Greek Sculpture, Dress Reform and Health in the 1880s pdf

Tài liệu Fashioning Archaeology into Art: Greek Sculpture, Dress Reform and Health in the 1880s pdf

... reclining would not have been possible in the corseted fashion of the period These paintings rebel against the restraint of movement in modern clothing The Parthenon sculptures associated with the ... Pheidias were increasingly influential and the influx of classical art into Britain through the mid nineteenth century, such as the sculptures from Nereid Monument in Lycia and the Mausoleum ... and the female body in the late nineteenth century On the one hand it illustrates an interest in the revival of Greek theatre and on the other it fetishizes the natural free flow of drapery on the...

Ngày tải lên: 19/02/2014, 10:20

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Báo cáo khoa học: Protein transport in organelles: Protein transport into and across the thylakoid membrane pptx

Báo cáo khoa học: Protein transport in organelles: Protein transport into and across the thylakoid membrane pptx

... for the interaction of the preprotein with the receptor The 16 ⁄ 23 chimera is retarded during translocation; early in the process, the protein assumes a structure within the membrane in which the ... to an N-terminal domain called the GTPasecontaining domain (G-domain) CpSRP54 also has a second domain designated the methionine-rich domain (M-domain) [48] Within cpSRP43, two domain structures ... terminal processing site Proteins destined to be transported by the Tat pathway contain a characteristic pair of arginine residues in the N-terminal region of the signal peptide, which gives the...

Ngày tải lên: 07/03/2014, 03:20

10 647 2
Báo cáo khoa học: Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel ppt

Báo cáo khoa học: Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel ppt

... changes in fluorescence Furthermore, considering that inhibition arises because inhibitors bound to the PAS hinder the entrance of acetylcholine to the CAS in the wildtype enzyme, it appears that, in ... substrate molecule is bound to the PAS) The traffic of choline outside the gorge is blocked when the PAS is occupied and choline stays inside the active site, resulting in inhibition [9] Parameter b ... of the alternative route compared to the main entrance, or to a partial overlap of the side chain of propidium and aflatoxin with the active site as it may span into the gorge specific equation in...

Ngày tải lên: 07/03/2014, 05:20

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Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt

Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt

... mLámin)1 The following gradients were used: incubations containing arbutin or salicin as substrate; 100% C initial, increasing D to 20% (10 min), 50% (15 min), 100% (5 min), held at 100% (5 min); ... generated during the PCR The positive clone was digested by a combination of XhoI and BamHI, and subsequently the cDNA insert was puri®ed using the Qiaquick PCR puri®cation kit and ligated into the XhoI ... 17% A/83% B initial (1 min), increasing B to 90% (10 min), held at 90% (4 min) The column was re-equilibrated (5 min) in the appropriate starting solvent conditions following gradient development...

Ngày tải lên: 08/03/2014, 16:20

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A walk in the Garden of Eden Genetic Trails into our African Past pptx

A walk in the Garden of Eden Genetic Trails into our African Past pptx

... human being together with the small amount of DNA that exists in the mitochondria the tiny organelles that are found in the cytoplasm of these cells In terms of size, the DNA molecule is so thin that ... disseminating interim research findings or they may be finished, publication-ready works Authors invite comments and suggestions from readers This paper was originally presented as the first in the ... representing a letter in the genetic code: adenine (A), thymine (T), guanine (G) and cytosine (C) But these four letters are sufficient to write the long chemical message encoded in the DNA There...

Ngày tải lên: 15/03/2014, 02:20

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AN INVESTIGATION INTO ATTITUDES TOWARDS WARER POLLUTION IN THE SHUSWAP LAKE AREA OF BRITISH COLUMBIA pot

AN INVESTIGATION INTO ATTITUDES TOWARDS WARER POLLUTION IN THE SHUSWAP LAKE AREA OF BRITISH COLUMBIA pot

... 71 residents 29.0pinions concerning t h e s e r i o u s n e s s of water p o l l u ti0ninB.C 73 30.0pinion concerning Shuswap Lake water q u a l i t y 73 31.0pinion concerning f u t u r e Shuswap ... T i t l e of Thesis r A Investigation i n t o Attitudes n Towards Water Pollution i n the Shuswap Lake Area of B r i t i s h Columbia Examining C omrnittee : Chairman: E J Hickin T d ' ~ i ... e a s e d b i o l o g i c a l productivity i n waters receiving the effluent Heberlein, i n conducting a f i e l d experiment concerning l i t t e r i n g behaviour, - - discovered t h a t t h...

Ngày tải lên: 15/03/2014, 16:20

125 471 0
Báo cáo khoa học: Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells ppt

Báo cáo khoa học: Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells ppt

... antioxidants, are absorbed in the intestine and secreted into lymph in chylomicrons, large triacylglycerol-rich lipoproteins which pass into the blood via the thoracic duct and are then rapidly metabolized ... with the opportunity to interact directly with the artery wall to in uence atheroma development, little is known about how the incorporation of antioxidants into the remnant particles in uences their ... 37 °C in 5% air/95% CO2 The cells were induced to differentiate into macrophages by incubation for 72 h in the presence of PMA (200 ngÆmL)1) Then, cells adhering to the culture plates, and the...

Ngày tải lên: 16/03/2014, 16:20

11 291 0
Mainstreaming gender into project cycle management in the fisheries sector pdf

Mainstreaming gender into project cycle management in the fisheries sector pdf

... identified by the women involved in the interventions, either through discussion groups, or other participatory approaches enabling women to express their own interests With this in mind, there must ... duly interviewed, or have otherwise played a direct role in securing the information or in utilising the analytical tools; - the information can be verified through group discussions with the ... participating small-scale fishing communities and their supporting institutions in Cambodia, Indonesia, the Philippines, Sri Lanka, Timor-Leste and Viet Nam By doing so the RFLP seeks to improve the...

Ngày tải lên: 23/03/2014, 05:22

105 408 0
the american banker as international investor have the new banking powers in the united states increased the volatility of lending into emerging economies

the american banker as international investor have the new banking powers in the united states increased the volatility of lending into emerging economies

... deregulation initiatives in the U.S banking industry and the volatility of emerging market lending by U.S banks during the same period This association was then explained by the linkages between the major ... of the banking industry and diversification of banking activities — and the increased volatility of lending into emerging economies Together, it argues that the U.S banking deregulation had the ... unintended and unanticipated side effect of increasing the volatility of U.S bank lending into emerging economies THE AMERICAN BANKER AS INTERNATIONAL INVESTOR: HAVE THE NEW BANKING POWERS IN...

Ngày tải lên: 03/06/2014, 02:14

184 315 0
báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx

báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx

... expressing CCR1, CCR2 or CCR5 mRNA within and around inflammatory foci in the spinal cord of rats with EAE, thus identifying potential determinants for trafficking of these cells to the CNS These findings ... in understanding the pathogenesis of MS is the reliable identification of phagocytes capable of degrading myelin Since infiltration of leukocytes including monocyte-derived macrophages into the ... immunization) of EAE show extensive inflammation involving the white and grey matter (D), with marked demyelination in the inflammatory areas (F) The majority of the infiltrating inflammatory cells are macrophages,...

Ngày tải lên: 19/06/2014, 22:20

13 559 0
Báo cáo hóa học: " Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors" pdf

Báo cáo hóa học: " Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors" pdf

... removing most of the enhancer machinery that is intrinsic to the retrovirus In this SIN template, a CMV promoter replaces the U3 region in the 5'LTR and drives expression of the retrovector mRNA in ... deletion to the 3'LTR, thus removing all the retroviral enhancers and the CAAT box (Figure 1A) Then, the SINCMV vector was made by incorporating the CMVIE enhancer-promoter into the construct ... a small part of the R region in the LTR Their results also suggested a negative interference of the tyrosinase enhancer on the viral enhancer when the latter was retained in the 3'LTR It has...

Ngày tải lên: 20/06/2014, 01:20

12 436 0
Báo cáo nghiên cứu khoa học " REPORT ON INVESTIGATIONS INTO MANGO SUPPLY CHAINS IN THE MEKONG DELTA VIETNAM 2005-2007 " ppt

Báo cáo nghiên cứu khoa học " REPORT ON INVESTIGATIONS INTO MANGO SUPPLY CHAINS IN THE MEKONG DELTA VIETNAM 2005-2007 " ppt

... of information, but the availability of information in these specific areas is limited Many retailers indicated that the supply chain they are involved in was the most effective place to obtain ... the Ho Chi Minh City‘s wholesale markets, have been in their line of business for over years (Figure 33) There has been a significant increase in the number of wholesales and business shops in ... retailers interviewed during the off season A total of wholesalers from the city of Cai Be, Tien Giang Province were interviewed and a further 10 collectors were interviewed in the Vinh Kim and...

Ngày tải lên: 22/06/2014, 12:20

114 437 0
Báo cáo nghiên cứu nông nghiệp "Investigations into the Pomelo Supply Chains in the Mekong Delta in Vietnam " ppt

Báo cáo nghiên cứu nông nghiệp "Investigations into the Pomelo Supply Chains in the Mekong Delta in Vietnam " ppt

... and farmers along the pomelo supply chains operating in the Bin Minh District and Vinh Long Province, Cai Be District, Tien Giang Province, in Vietnam in July 2005 to May in 2006 Interviews were ... of the poverty reduction in Vietnam can be traced to the high annual economic growth combined with integration into international markets, increasing agricultural exports, investments in infrastructure ... pomelo into juice and jam LOCAL PACKING AGENTS Packing agents also play an important role They bear all the costs of collecting, sorting, paying the taxes and transporting the fruit to the wholesalers...

Ngày tải lên: 22/06/2014, 13:20

63 479 1
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