... ongoing discussion intrinsic to the doctor–patient relationship Establishing why rather than whether the patient accepts or rejects treatments gives insight into the individual’s world view and ... hospitalized patients: effectiveness with the patient self-determination act and the SUPPORT intervention SUPPORT Investigators Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment ... safeguards autonomous choice Competing interests The author declares that they have no competing interests References Tillyard ARJ: Ethics review: ‘Living wills’ and intensive care – an overview of...
... agitation and behavioral problems inolderpatientsin acute care settings The objectives of this study were to (a) determine the quantity and quality of behavioral problems inolder hospitalized patients ... also asked to participate in the study All patientsandcaregivers provided informed consent before participating All of the patients were male The patients ranged in age from 61 to 85 years, ... to the patientsin the study assessed history of substance abuse and psychiatric illness, by both obtaining information from the patient themselves and by reviewing patient charts We also included...
... becoming one of the most significant issues intreatment decision-making, in general, and more so in prostate cancer [1] Thus late rectal and urinary damage became a major concern in prostate cancer; ... summarized in Table The values of the last late GI and GU toxicity observed inpatients during their last inspection are shown In the cohort of patients included in the WP group, pretreatment ... results, and evaluates the relationships between pretreatment, acute and late rectal and urinary syndromes and tumor-, patient- and treatment- related factors In the last years of the study, we investigated...
... always during RT Twenty-six patients received combined androgen blockade (CAB) consisting of antiandrogen and gonadotropin releasing hormone analogue (GnRH) Three patients received antiandrogen ... abdomen and pelvis and a total-body bone scan When clinically indicated a chest x-ray and/ or thoracic CT was performed Based on these examinations clinical staging was defined according to the ... receiving at least 95% of dose, corresponding to 76 Gy) and the Dmax and Dmin (maximum and minimum dose within the PTV) were calculated from the dose volume histograms Follow-up protocol Patients...
... chemopreventive agents, including resveratrol [26,27], brassinin [28,29], and deguelin [30,31] Resveratrol is present in grapes, red wine and peanuts, brassinin is from Chinese cabbage, and deguelin is from ... apoptosis in SW480 human colon cancer cells To investigate the effects of IxoA on apoptosis, we 5720 used acridine orange ⁄ ethidium bromide staining and DAPI staining and found a marked increase in ... microscope slides, fixed in formalin and methanol, and stained with DAPI Stained nuclei were visualized using a fluorescent microscope Blebbing of the membrane, chromatin aggregation, and nuclear condensation...
... HERs are commonly activated upon binding of a ligand in their extracellular domain, resulting in dimerization of HERs and triggering the intrinsic tyrosine kinase activity of the receptors responsible ... fusion gene encoding the chimeric protein of caspase-8 and the ligand-binding domain (LBD) of ERα and introduced the gene into breast cancer cell lines (Zhao et al, 2011) Upon administration of ... organs, including mammary glands, in female goats and sheep (Glascock and Hoekstra 1959) This finding was a crucial observation to understand the role of estrogens in processes involving target...
... of staying within the natal group and engaging in helping activities, versus leaving the group and refraining from helping, and therefore may explain the extent of cooperative breeding in a given ... female subordinates (5 mm < SL < 60 mm, Dierkes et al 2005) assist the breeders, engaging in all tasks relevant to breeding: fanning and cleaning eggs, digging out shelters, cleaning breeding shelters ... of carrying sand away from the shelters in a 10-min observation for each focal (‘digging alone’) In the evening of the same day, a large male and female was added, who accepted the focal individual...
... described, including survivin-2α, survivin-2B, survivin-ΔEx3, and survivin-3B [12-15] While survivin-2α and survivin-3B are truncated forms, survivin2B results from alternating splicing at the interface ... RT-PCR in normal tissues, and oral cancer cell lines and primary oral cancer tisExpression of survivin mRNA as assessed by RT-PCR in normal tissues, and oral cancer cell lines and primary oral cancer ... blotting analysis of survivin protein in oral cancer cell lines Western blotting analysis of survivin protein in oral cancer cell lines Lysates from oral cancer cell lines or normal oral mucosal...
... (27.3% in case of leukemic patients, 47.6% in case of solid-tumor cancer patients) In both leukemic patientsand solid-tumor cancer patients, gram-negative bacteria causing nosocomial RTI were mainly ... predominant gram-negative bacteria in Bloodstream Infections (BSI), Urinary Tract Infections (UTI), Respiratory Tract Infections (RTI), Gastro-Intestinal Tract Infections (GITI), and Skin Infections ... predominant gram-negative bacteria in Bloodstream Infections (BSI), Urinary Tract Infections (UTI), Respiratory Tract Infections (RTI), Gastro-Intestinal Tract Infections (GITI), and Skin Infections...
... carcinoma patients, unaffected colonic mucosa, carcinoma tissue) one has to keep in mind the differences in sample sizes and applied tests The highly significant difference in CD between blood and ... patients confirming the results of former studies investigating Vβ-repertoire restrictions in blood of patients with other tumor entities, which have been interpreted as indication for the induction ... origin, we found a negative correlation between HAC/PBGD and CD (Figure 3) as well as HAC/PBGD and n(F) (not shown) However, separate analysis of the samples originating from blood and originating...
... SQ participated in acquiring clinical samples and follow-up clinical information MSC participated in study design and coordination, data analysis and interpretation and final writing of the manuscript ... analysis and interpretation, and drafted the manuscript PP and LG participated in acquiring clinical and laboratory data, data analysis and data interpretation and drafted the manuscript LG, JV, and ... Methods Lung cancer cell lines Six NSCLC cell lines consisting of three adenocarcinoma cell lines (A549, H522 and H358), two large carcinoma cell lines (H460, H661), and one squamous cell carcinoma...
... curative intent, and had no concomitant tumors or comorbidity requiring hospital visits There were no age restrictions Patients were included in the trial after finalizing treatmentand after giving ... Research andTreatment of Cancer QLQC30: a quality-of-life instrument for use in international clinical trials in oncology J Natl Cancer Inst 1993, 85(5):365-376 Bottomley A, Aaronson NK: International ... measurement in randomized clinical trials in breast cancer – taking stock Journal of the National Cancer Institute 2003, 95(4):263-281 Montazeri A: Health-related quality of life in breast cancer patients: ...
... effects in favor of the biofeedback-based training were found for weight-distribution during standing • Training gait with auditory (and visual) biofeedback inolderpatients post-stroke In out ... visual information easy to understand and grasped the concept of training more effectively than with conventional treatment • Training gait with auditory (and visual [28]) biofeedback inolderpatients ... of COP vs no intervention 3× wk, wks 20-30 minutes Total: 240360 Sway during standing, varying vision and base of support & weightshifting during standing BBS, activity level Continuous visual...
... [49,50] In the present study, we have described (1) temporal changes during the pre -treatment period in Sn-aa andin HD and (2) how these changes in Sn-aa and HD relate to treatment outcome Baseline ... the dominant strain at week of therapy represents an average of 90% of the total viral population Interestingly, the dominant strain present at baseline was still present inpatientsin the SVR ... course of therapy and after the end of treatmentIn all TF cases at the L time point, where sample was available, the pre-dominant strain was either the dominant strain or a minor strain already present...
... foramen ovale and cryptogenic stroke inpatients 55 years of age or olderand to compare the findings with those for younger patients Our study population included all consecutive patients 18 to ... the remaining 503 patients The following routine diagnostic tests were performed in all patients: cranial computed tomography, magnetic resonance imaging (MRI) of the brain, or both; and duplex ... patent foramen ovale inolderpatients with cryptogenic stroke than in younger patients. 15 In addition to the fact that alternative causes should be taken into account inolder patients, it should...
... HERs are commonly activated upon binding of a ligand in their extracellular domain, resulting in dimerization of HERs and triggering the intrinsic tyrosine kinase activity of the receptors responsible ... fusion gene encoding the chimeric protein of caspase-8 and the ligand-binding domain (LBD) of ERα and introduced the gene into breast cancer cell lines (Zhao et al, 2011) Upon administration of ... organs, including mammary glands, in female goats and sheep (Glascock and Hoekstra 1959) This finding was a crucial observation to understand the role of estrogens in processes involving target...
... cases of invasive cancer than in cases of non-invasive cancer [8,9] The principal objective of this study was to determine the relationship between serum IL-6 and CRP levels and staging and prognosis ... Murai M: Serum interleukin as a prognostic factor inpatients with prostate cancer Clin Cancer Res 2000, 6:2702-2706 Wise GJ, Marella VK, Talluri G, Shirazian D: Cytokine variations inpatients with ... significance of interleukin serum levels inpatients with ovarian cancer Br J Cancer 1995, 71:354-356 De Vita F, Orditura M, Auriemma A, Infusino S, Roscigno A, Catalano G: Serum levels of interleukin as...
... pancreatic cancerand underestimate the benefit This negative view of surgery may be limiting the options presented to patients When examining the treatmentand referral patterns of patients with ... diagnostic imaging, cytology, histology, laboratory and clinical results Each patient was staged according to the Results Survey A total of 480 physicians were included in the initial mailing, however, ... began the operation and were considered unresectable, and 85 (69%) received no treatment (Table - Demographic outline andtreatment patterns of patients diagnosed with pancreatic cancer) The only...
... Stefanick ML: Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized ... visit (annually) for discovering the LRR In addition to routine clinical examination, disease assessment included mammography, chest x ray and liver ultrasonography All patients received postoperatively ... within 2.5 years (P\0.001) [32] In the BIG 1-98 trial, significant predictors of early recurrence in multivariate analysis also included tumor size and grade and node positivity [33] andin the...
... during the treatment period The patients could start their oral feeding without any inconvenience and were discharged in good conditions afterwards Figure The esophagus and jejunum The arrow indicates ... the feeding tube located in the jejunum away from the leak area Each point is indicated by arrows Discussion Gastric cancer is a very common cancer worldwide and surgery is the only treatment ... anastomotic failure following total gastrectomy Acta Chir Scand 1987, 153(4):303-6 Sasako M: Role of surgery in multidisciplinary treatment for solid cancers Int J Clin Oncol 2004, 9:346-351 10...