cancer stem cells ý pdf

Báo cáo y học: "Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model" pps

Ngày tải lên : 10/08/2014, 05:21

... overexpression P63+ basal /stem cells were transformed into AR+ or ARcancer cells but rarely into ChgA+ neuroendocrine cancer cells Conventional human prostate cancer cells include malignant cells of luminal, ... P63+ basal /stem cells and to examine whether these cancer cells can maintain stem cell characteristics after metastasis More importantly, we intended to elucidate whether P63 + basal /stem cells can ... 1996, 30:201-205 Collins AT, Maitland NJ: Prostate cancer stem cells Eur J Cancer 2006, 42:1213-1218 Lawson DA, Witte ON: Stem cells in prostate cancer initiation and progression J Clin Invest 2007,...

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Báo cáo y học: "Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic study" pptx

Ngày tải lên : 10/08/2014, 09:22

... expression profiling of cancer stem cell in human lung adenocarcinoma A549 cells Mol Cancer 2007, 6:75 19 Pfeiffer MJ, Smit FP, Sedelaar JP, Schalken JA: Steroidogenic enzymes and stem cell markers ... AK1C1 [18], AK1C3 [19] and CD44 [20] have been proposed to be the markers of cancer stem cells Their expression in tumor cells could correlate with their aggressive biological behavior, drug resistance ... variety of malignant tumor cells In particular, AK1C1, and AK1C3 are reported in human non-small cell lung carcinoma (A549) cells [21], and a high expression of AL1A1 in lung cancer cell lines, especially...

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cancer stem cells theories and practice_part2 pdf

Ngày tải lên : 12/08/2014, 06:20

... normal stem cells to cancer stem cells Adult normal stem cells represent one purported origin of cancer stem cells What causes the transformation from normal stem cells to cancer stem cells? ... version www.adultpdf.com 50 Cancer Stem Cells Theories and Practice Genomic instability in cancer stem cells as a potential mechanism for cancer cell heterogeneity If cancer stem cells are genomically ... cancer stem cells Is the genome inherently unstable in stem cells? If the answer is yes, cancer stem cells may have two reasons for having an unstable genome: being a stem cell as well as a cancer...

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Báo cáo y học: "Population genetics of cancer cell clones: possible implications of cancer stem cells" pptx

Ngày tải lên : 13/08/2014, 16:20

... process The inclusion of cancer stem cells into models of clonal evolution leads to the prediction that in cancers which contain stem cells, clonal evolution of stem cells may be considerably ... 14 Reya T, Morrison SJ, Clark MF, Weisman IL: Stem cells, cancer and cancer stem cells Nature 2001, 414:105-111 15 Shipitsin M, Polyak K: The cancer stem cell hypothesis: in search of definitions, ... selection with non -stem cells could furthermore provide a method of testing the relative strength of selection of stem cells and non -stem cells and thereby indirectly testing the entire stem cell paradigm...

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Báo cáo y học: " Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions" pps

Ngày tải lên : 14/08/2014, 08:21

... primitive cancer cells PTL induces apoptosis in primitive cancer cells Percent viability of prostate cancer cells and cells from a patient with BPH treated with increasing concentrations of PTL Cells ... signature Stem cells Stem cells (c) Committed basal Committed basal Stem Committed cells basal (d) Malignancy signature Tumour Birnie et al R83.3 Gleason included Benign Figure Distinctive stem cell ... cultures of cancer stem cells is likely to be important for maintaining gene expression patterns similar to cancer stem cells in vivo Genome Biology 2008, 9:R83 Genome Biology 2008, Cancer BPH...

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báo cáo hóa học:" Ovarian cancer: emerging concept on cancer stem cells" docx

Ngày tải lên : 20/06/2014, 07:20

... multi-potential stem cells, tissue-specific stem cells, progenitor cells, mature cells, and cancer cells described the direct isolation of populations containing cancer stem cells in various ... normal stem cells and cancer stem cells, there are mechanistic differences in some cancers Interestingly, the mechanistic differences in selfrenewal between normal stem cells and cancer stem cells ... lineage of cancer stem cells [58] Ovarian cancer stem cells, like somatic stem cells, are shown to be capable of unlimited self-renewal and proliferation In general, multi-potent cancer stem cells...

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báo cáo khoa học: " MicroRNAs involved in neoplastic transformation of liver cancer stem cells" pot

Ngày tải lên : 10/08/2014, 10:20

... between HCC cells and fetal liver cells Discussion There is a growing realization that many cancers may harbor a small population of cancer stem cells (CSCs) These cells not only exhibit stem cell ... accumulation of evidence for cancer stem cells , it is proposed that miRNAs might play a role in malignant transformation from normal stem cells into cancer stem cells Recent studies have partially ... long-lived somatic stem cells Therefore, markers of “normal” stem cells are being sought with the expectation that these molecules are also expressed by cancer Page of 10 stem cells, and can be...

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báo cáo khoa học: " Microarray-based analysis of microRNA expression in breast cancer stem cells" doc

Ngày tải lên : 10/08/2014, 10:20

... Experimental & Clinical Cancer Research 2010, 29:174 http://www.jeccr.com/content/29/1/174 cancer stem cells http://www.mirbase.org/ Thus, the identification of cancer stem cell-related miRNAs ... isolated tumorigenic breast cancer cells with stem/ progenitor cell properties from a breast cancer cell line, and Huang [17] screened side population (SP) cells from a breast cancer cell line Here, ... in breast cancer tissue than in paraneoplastic tissue [26-28] These studies indicate that miR-122a is likely to be an important gene regulatory factor in cancer cells, even cancer stem cells Another...

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cancer stem cells theories and practice_part1 pps

Ngày tải lên : 12/08/2014, 06:20

... and Cancer Stem Cells. ” The text is sharply focused as they ponder, “What causes the transformation from normal stem cells to cancer stem cells? ” The authors suggest that cancer stemloid (or stem ... Active in Leukemic Stem Cells to Overcome Drug Resistance 401 Miaorong She and Xilin Chen Chapter 21 Cancer Stem Cells and Chemoresistance Suebwong Chuthapisith Chapter 22 Cancer Stem Cells in Drug ... Activated in Cancer Stem Cells in Breast Cancer, ” namely, that “inﬂammatory cytokines and chemokines are critical components for the maintenance of breast cancer stem cells. ” Speciﬁcally, cancer- associated...

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cancer stem cells theories and practice_part3 pot

Ngày tải lên : 12/08/2014, 06:20

... version www.adultpdf.com 80 Cancer Stem Cells Theories and Practice Discovery of neural and glioma stem cells The discovery of adult neural stem cells paved the way for the glioma stem cell field ... Birnbaum, D & Wicha, M.S (2009) Breast cancer cell lines This is trial version www.adultpdf.com 74 Cancer Stem Cells Theories and Practice contain functional cancer stem cells with metastatic capacity ... normal neural stem cells and glioma stem cells, and may identify new CD133- glioma stem cells 4.4 New markers: Podoplanin and Integrin Alpha There are two new promising cancer stem cell markers...

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cancer stem cells theories and practice_part4 ppsx

Ngày tải lên : 12/08/2014, 06:20

... chemiluminescence system (ECL, Amersham) This is trial version www.adultpdf.com 124 Cancer Stem Cells Theories and Practice This is trial version www.adultpdf.com Cancer Stem Cells in Lung Cancer: Distinct ... system (DAKOcytomation, Carpinteria, CA), and the nuclei were counterstained with hematoxylin This is trial version www.adultpdf.com 126 Cancer Stem Cells Theories and Practice Table Cancer stem ... Eaves, C.J., Jamieson, C.H., Jones, D.L (2006) Cancer stem cells perspectives on current status and future directions: AACR Workshop on cancer stem cells Cancer Res, 66, 9339-9344 [11] Lobo, N.A.,...

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cancer stem cells theories and practice_part8 pptx

Ngày tải lên : 12/08/2014, 06:20

... Kosik, 2008) According to this cancer stem cell hypothesis, cancer stem cells are tumorinitiating cells that proliferate uniquely through self-renewal Cancer stem cells are thought to only constitute ... pathways in cancer stem cells This is trial version www.adultpdf.com MicroRNAs: Small but Critical Regulators of Cancer Stem Cells 299 Fig Potential stem cell miRNAs” that modulate stem cell ... supporting the term cancer stem cells Self-renewal of cancer stem cells is thought to be a likely cause of the resistance seen of current cancer treatment and relapse in cancer patients Recently,...

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cancer stem cells theories and practice_part9 docx

Ngày tải lên : 12/08/2014, 06:20

... review this issue with depth Stem cells and cancer stem cell theory Stem Cells In order to understand cancer stem cells a brief description of normal adult stem cells and the environment in which ... This is trial version www.adultpdf.com Cancer Stem Cells as a New Opportunity for Therapeutic Intervention 381 Cancer Stem Cells Cancer Stem Cells (CSCs) are tumor cells different from the rest ... propensity to form tumours Therefore these cells are referred to as cancer stem cells (CSC) or cancer stem- like cells or, better, tumour-initiating cells (TICs) The terminology, while not too...

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Báo cáo y học: "Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells" pdf

Ngày tải lên : 09/08/2014, 10:23

... of cells was determined spectrophotometrically entiation of human mesenchymal transcripts Expression of BMP-2 and chordinstem cells during osteogenic differentiation of human mesenchymal stem cells ... assay at 3, and days of culture After and days, cells treated with chordin siRNA had decreased proliferation, as compared with untreated cells, and cells treated with transfection reagent only or ... Dickinson, Franklin Lakes, NJ, USA) After weeks in primary culture, cells were passaged at seeding densities between 100 and 1,000 cells/ cm2, trypsinised and stored in Recovery Cell Culture Freezing...

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Báo cáo y học: "Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect" pdf

Ngày tải lên : 09/08/2014, 10:23

... 25 26 Multilineage potential of adult human mesenchymal stem cells Science 1999, 284:143-147 Prockop DJ: Marrow stromal cells as stem cells for nonhematopoietic tissues Science 1997, 276:71-74 ... citation purposes) vial mesenchymal stem cells into cartilage defect Application of low-invasive local adherent technique to transplant synovial mesenchymal stem cells into cartilage defect (a) For ... injected cells adhered to synovial tissue (data not shown), and only a small portion of the cells adhered to the cartilage defect Injection of more cells would increase the number of cells that...

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Báo cáo y học: " Over-expression of HO-1 on mesenchymal stem cells promotes angiogenesis and improves myocardial function in infarcted myocardium" pdf

Ngày tải lên : 10/08/2014, 05:21

... apoptosis and improved heart function Stem Cells 2007, 25:2118-2127 Wang D, Shen W, Zhang F, Chen M, Chen H, Cao k: Connexin43 promotes survival of mesenchymal stem cells in ischaemic heart Cell Biol ... mobilization of bone marrow stem cells[ 21] In addition, FGF2 also have the potential to promote angiogenesis, and regulate proliferation, migration, differentiation of vascular cells[ 22,23] Lin’study ... nonadherent cells were removed by a medium change at 72 h and every four days thereafter After two passages, homogeneous MSCs that devoid of hematopoietic cells were used A total of × 106 cells/ ml...

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Báo cáo y học: "Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation" pdf

Ngày tải lên : 10/08/2014, 05:21

... Therefore, the exogenous stem/ progenitor cells, such as embryonic stem cells (ESCs), bone marrowor fat-derived mesenchymal stem cells (MSCs), and recently amniotic fluid stem/ progenitor cells, could be ... Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages Stem Cells 2008, 26:2902-2911 Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse ... stem cells Stem Cells 2009, 27:2655-2666 Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, Lensch MW, Cowan C, Hochedlinger K, Daley GQ: Disease-specific induced pluripotent stem cells...

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Báo cáo y học: "Sphingosine-1-phosphate promotes the differentiation of human umbilical cord mesenchymal stem cells into cardiomyocytes under the designated culturing conditions" pdf

Ngày tải lên : 10/08/2014, 05:21

... Regard to the Source of Fetus-Derived Stem Cells Stem cells 2007, 25:2886-2895 Wu KH, Mo XM, Zhou B, Lu SH, Yang SG, Liu YL, Han ZC: Cardiac potential of stem cells from whole human umbilical cord ... and endothelial cells[ 1-3] Given these characteristics, particularly the plasticity and developmental flexibility, UC stromal cells are now considered an alternative source of stem cells and deserve ... Key Targets Associated with Survival, Proliferation, and Pluripotency in Human Embryonic Stem Cells Stem Cells Dev 2008, 17:1195-1206 Rodgers A, Mormeneo D, Long JS, Delgado A, Pyne NJ, Pyne S:...

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