can the instrument be applied to a particular population setting and question of interest

Toxicological Risk Assessment of Chemicals: A Practical Guide - Chapter 1 ppt

Toxicological Risk Assessment of Chemicals: A Practical Guide - Chapter 1 ppt

Ngày tải lên : 12/08/2014, 04:22
... LLC ß 2007 by Taylor & Francis Group, LLC Abbreviations and Acronyms ACGIH ADD ADI ADME AF ALARA AOEL AR ARfD ARI ATC ATRA ATSDR AUC BEI BIAC BMD BMDL BMR BUA CA CAA CAFE CAS CCOHS CCPR CDC ... and technical factors with relevant risk assessment information relating to a hazard so as to develop, analyze, and compare regulatory and non-regulatory options and to select and implement appropriate ... (Chapter 2) The data for hazard assessment (Chapter 3) and the hazard assessment process, i.e., identification and characterization of the various toxicological effects and the associated test methods...
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Toxicological Risk Assessment of Chemicals: A Practical Guide - Chapter 5 potx

Toxicological Risk Assessment of Chemicals: A Practical Guide - Chapter 5 potx

Ngày tải lên : 12/08/2014, 04:22
... however, there is no general, international, and scientific recommendation to a standard value The available data generally support a default factor of 10 and a factor of 10 is considered to protect the ... to Kalberlah and Schneider (1998), a factor of 10 ensures protection of much greater than 99% of the population if the average behavior of the chemicals is taken as the basis In the case of the ... 3.16-fold factor was applied to the mean for the major group in the population As the majority of relevant data relate to the toxicokinetics of drugs in Caucasian adults, this group was taken as the reference...
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Toxicological Risk Assessment of Chemicals: A Practical Guide - Chapter 7 ppsx

Toxicological Risk Assessment of Chemicals: A Practical Guide - Chapter 7 ppsx

Ngày tải lên : 12/08/2014, 04:22
... 1.70 Ershow and Cantor (1989) Health and Welfare Canada (1981) Health and Welfare Canada (1981) Ershow and Cantor (1989) Health and Welfare Canada (1981) Ershow and Cantor (1989) Total 1.38 1.41 ... has specified the daily amount of soil ingested as 20 mg=day This is a median value from Health and Welfare Canada (the national Department of Health of the Government of Canada) It has not been ... and= or statistical analysis CHAD is a master database providing access to other human activity databases using a consistent format This facilitates access and retrieval of activity =and questionnaire...
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Toxicological Risk Assessment of Chemicals: A Practical Guide - Chapter 9 (end) ppt

Toxicological Risk Assessment of Chemicals: A Practical Guide - Chapter 9 (end) ppt

Ngày tải lên : 12/08/2014, 04:22
... primarily to water and health regulators, policymakers and their advisors and intended to be used as a basis for the development of national standards that may ensure the safety of drinking-water ... programs US-EPA refers to chemicals that cause serious health and environmental hazards as hazardous air pollutants (HAPs) or air toxics The 1970 Clean Air Act gave US-EPA authority to list air toxics ... protect against both naturally occurring and man-made contaminants that may be found in drinking water US-EPA, States, and water systems then work together to make sure that these standards are met...
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Statistical Methods of Valuation and Risk Assessment: Empirical Analysis of Equity Markets and Hedge Fund Strategies

Statistical Methods of Valuation and Risk Assessment: Empirical Analysis of Equity Markets and Hedge Fund Strategies

Ngày tải lên : 16/04/2013, 20:00
... concept of concordance and discordance which informally says that a pair of random variables are concordant if large values of one tend to be associated with large values of the other and small values ... risk management Measuring risk and analysing ways of controlling and allocating it require a wide range of sophisticated mathematical and computational tools Indeed, mathematical models of modern ... regarding their marginal behaviors and allow us to evaluate the conditional probabilities that one strategy takes a certain value given that the second strategy takes another value To reach this aim...
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Risk Assessment of Fenthion Oxide Derivatives in Aqueous Environment

Risk Assessment of Fenthion Oxide Derivatives in Aqueous Environment

Ngày tải lên : 05/09/2013, 10:15
... Health Sci., 52(3), 313-319 Tahara M., Kubota R., Nakazawa H., Tokunaga H and Nishimura T (200 8a) The behavior and cholinesterase inhibitory activity of fenthion and its products by light and ... spectrometry: a powerful approach for the sensitive and rapid multiclass determination of pesticides and transformation products in water, Analyst, 129, 38-44 Tahara M., Kubota R., Nakazawa H., Tokunaga ... 5112-5118 Tahara M., Kubota R., Nakazawa H., Tokunaga H and Nishimura T (2006) Analysis of active oxon forms of nine organophosphorus pesticides in water samples using gas chromatography with mass spectrometric...
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Radiological risk assessment for Al-Twuaitha nuclear site in Iraq

Radiological risk assessment for Al-Twuaitha nuclear site in Iraq

Ngày tải lên : 05/09/2013, 16:10
... analysis Risk analysis assumption for the probability distribution is essential to characterize the key parameters and variables with a decision to estimate the risk profile and to estimate the ... of the present work is to evaluate the risk of radioactivity in the contaminated soil using crystal ball software and samples taken at different points from the surrounding areas of the research ... simulation, and optimization It gives unparalleled insight into the critical factors affecting risk True variability and uncertainty for each variable and parameter could be introduced as probability...
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Practical industrial safety, risk assessment and shutdown systems, elsevier (2003)

Practical industrial safety, risk assessment and shutdown systems, elsevier (2003)

Ngày tải lên : 02/01/2014, 09:47
... dedicated to these specialized tasks Bear in mind that some of the deeper parts of this standard will be applicable to manufacturers of certified safety PLCs and their associated software packages ... standard the easier it becomes to enforce laws requiring conformance to that standard Here we take a look at how we have arrived at the point where new international standards are available Then ... need (and this can be one of the hardest things to agree on) The target is to reduce the risk from the unacceptable to at least the tolerable This principle has a fundamental impact on the way we...
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Tài liệu Risk Management Guide for Information Technology SystemsRecommendations ppt

Tài liệu Risk Management Guide for Information Technology SystemsRecommendations ppt

Ngày tải lên : 22/01/2014, 02:20
... environment and requirements Some of the “vulnerabilities” flagged by the automated scanning software may actually not be vulnerable for a particular site but may be configured that way because their ... given to the threat and vulnerability pairs that have the potential to cause significant mission impact or harm Also, in safeguarding an organization’s mission and its IT systems, because of each ... system activities and violations cannot be monitored and tracked if the system audit function is disabled, and security cannot be maximized to protect the organization’s confidential data and mission...
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Tài liệu Don’t navigate risky waters without internal auditors: Guidance on leveraging audit analytics for risk assessment pptx

Tài liệu Don’t navigate risky waters without internal auditors: Guidance on leveraging audit analytics for risk assessment pptx

Ngày tải lên : 18/02/2014, 05:20
... breaches or indicators of risk, how can this be communicated to management? The goal is to make these processes integral to risk assessment and audit activities, and to make them sustainable and ... retail environment for compliance with corporate policy and fraud ƒƒ Once a new process is automated, staff can move on to other areas and apply a rule of thumb that the average analysis can be ... ability to analyze the transactional data that they generate This unique mix of business and IT domains enables internal audit to evaluate the operating effectiveness of these processes and the...
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Tài liệu ASSESSMENT OF ANAEROBIC TREATMENT OF SELECT WASTE STREAMS IN PAPER MANUFACTURING OPERATIONS pot

Tài liệu ASSESSMENT OF ANAEROBIC TREATMENT OF SELECT WASTE STREAMS IN PAPER MANUFACTURING OPERATIONS pot

Ngày tải lên : 22/02/2014, 09:20
... Juan Ernesto Debedout and Jean Carlo Tellini, for their support and commitment to the project, as well as to Manuel Sibaja, Yunier Campos, Noiry Madrigal, Susan Alfaro, and all other members of ... streams was evaluated for a paper plant located in Central America, to assess to what extent certain waste streams can be anaerobically digested, to what extent energy can be produced in the form of ... system Therefore, not only the nature of the substrates to be digested is important, but also operational and environmental parameters that influence the behavior and fate of the microbial populations...
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Communicable disease risk assessment and interventions ppt

Communicable disease risk assessment and interventions ppt

Ngày tải lên : 05/03/2014, 12:20
... Figure 1) The area which has been declared a State Disaster Area has a total population of 24 million Cyclone Nargis (Category 3-4) developed over the Bay of Bengal and made landfall at 16.00 ... malnutrition and 10% as being wasted (acute malnutrition) (UNICEF) Major causes of death are usually due to malaria, respiratory and diarrhoeal diseases Given the structural damage caused by the ... well after the acute phase of the crisis has passed and national and international relief workers have been repatriated 2.2 Water/sanitation/hygiene-related and foodborne diseases The populations...
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A Knowledge-Based Approach to Network Security: Applying Cyc in the Domain of Network Risk Assessment pptx

A Knowledge-Based Approach to Network Security: Applying Cyc in the Domain of Network Risk Assessment pptx

Ngày tải lên : 05/03/2014, 23:20
... plan goals, launch the planner and view the attack plans generated For example, a user can state the goal “An external user with no initial access gains administrator/root access to target.mynetwork.net.” ... users a deep analysis of the state of their network, particularly by demonstrating feasible attack plans that could be launched against it Widespread application of CycSecure and adoption of its ... Undercoffer and Pinkston [2002] Their ontology of attacks is “targetcentric,” emphasizing the means, consequences and locations of attacks as attack-type discriminators CycSecure’s ontology of faults...
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Coaching Standardized Patients For Use in the Assessment of Clinical Competence pot

Coaching Standardized Patients For Use in the Assessment of Clinical Competence pot

Ngày tải lên : 08/03/2014, 16:20
... understand the patient in the same way, as part of standardization, and to tweak performances that are already close to what you want This is a significant part of what coaching is about There ... Kitrell, Robert MacAulay, and Anita Richards, all of whom read parts or all of the manuscript and helped me see what was needed with fresh eyes Melinda Schwakhofer and Angela Atencio, the SP educators ... Carnovsky, one of the original actors of the Group Theatre, also aptly describes the ideal relationship of the SP coach and the SPs It is the coach’s vision of the patient case that enables the...
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biểu đồ ma trận – biểu đồ rủi ro, risk assessment matrix chart

biểu đồ ma trận – biểu đồ rủi ro, risk assessment matrix chart

Ngày tải lên : 12/03/2014, 16:52
... slide.tailieu.vn BIỂU Matrix – BIỂU RiskĐỒ MA TRẬN3D ĐỒ RỦI RO Phụ tiêu đề Tiêu đề MEDIUM RISK Rủi ro v a 1.Mô tả nội dung 2.Dữ liệu có HIGH RISK Rủi ro cao LOW RISK Rủi ro thấp CRITICAL RISK ... Nguy quan trọng MEDIUM RISK Rủi ro v a 4.… 5.… 6.… 7.… 8.… KHẢ NĂNG - LIKELIHOOD 3.Ghi LOW RISK Rủi ro thấp LOW RISK Rủi ro thấp HIGH RISK Rủi ro cao MEDIUM RISK Rủi ro v a TÁC ĐỘNG - IMAPACT Nội ... - Probable Dữ liệu Không thể -Impossible Dữ liệu HẬU QUẢ - CONSEQUENCES Nhỏ - Minor V a phải - Moderate Nghiêm trọng - Major Mô tả nội dung Mô tả nội dung Mô tả nội dung Có thể xảy - Probable...
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biểu đồ powerpoint ma trận đánh giá rủi ro, risk assessment matrix chart

biểu đồ powerpoint ma trận đánh giá rủi ro, risk assessment matrix chart

Ngày tải lên : 12/03/2014, 16:52
... Sản phẩm slide.tailieu.vn ANSOFF GROWTH MATRIX Chỉnh s a Nội dung Nội dung Nội dung Hiện Thị trường Mới Nội dung Nội dung Hiện Nội dung Nội dung Chỉnh s a Mới Sản phẩm slide.tailieu.vn ... Nội dung Nội dung slide.tailieu.vn Nội dung Nội dung Nội dung Nội dung Nội dung Nội dung Nội dung Nội dung Nội dung Nội dung Nội dung slide.tailieu.vn ANSOFF GROWTH MATRIX Nội dung Tồn Nội dung ... trường Nội dung Nội dung Mới Hiện • Hiện Chỉnh s a Nội dung • Nội dung • Nội dung Nội dung Nội dung Mới Sản phẩm slide.tailieu.vn ANSOFF GROWTH MATRIX Nội dung Nội dung Nội dung Nội dung Nội dung...
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A meta analysis and risk assessment of heavy metal uptake in common garden vegestable

A meta analysis and risk assessment of heavy metal uptake in common garden vegestable

Ngày tải lên : 15/03/2014, 23:10
... Superfund (RAGS) (EPA 1989) Gather all data available from the site investigation and sort by medium Evaluate the analytical methods used Evaluate the quality of data with respect to sample quantitation ... plants than was leached through the profile (Khan and Frankland 1983) Several factors may influence the content and distribution of heavy metals in soil Some of these factors are parent material, ... data compilation and evaluation, 2) exposure assessment, 3) toxicity assessment, and 4) risk characterization (EPA 1989; DOE 1999) The type, quality, and availability of data from a particular...
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TOXICITY-PATHWAY-BASED RISK ASSESSMENT PREPARING FOR PARADIGM CHANGE docx

TOXICITY-PATHWAY-BASED RISK ASSESSMENT PREPARING FOR PARADIGM CHANGE docx

Ngày tải lên : 16/03/2014, 14:20
... the only ligand to bind to the AHR, and that raises the question of whether results from one ligand can be extrapolated to all ligands That has essentially been done for several classes of halogenated ... be interpretation of the data Kavlock noted that the goal of ToxCast is to determine the probability that a chemical will cause a particular adverse health effect The data must be generated and ... decisions Daston mentioned several public databases (DSSTox, ACTOR, and ToxRefdB) that are available for conducting similar searches and emphasized the importance of public data-sharing Summary of the...
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