can non small cell lung cancer spread to the brain
Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
... body radiotherapy for stage I non- small cell lung cancer. Radiother Oncol 2007, 85:429-434.39. Sinha B, McGarry RC: Stereotactic body radiotherapy for bilat-eral primary lung cancers: the Indiana ... base) for purposes ofcontouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extendinferiorly to the apex of the heart. The defined ipsilateral ... protocolRecommendations for implementing stereotactic radiotherapy in peripheral stage IA non- small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL studyCoen...
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báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
... Pisani P: Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001, 94:153-156.2. Non- small Cell Lung Cancer Collaborative Group: Chemotherapyin non small cell lung cancer: a meta-analysis ... G,Gozzelino F, Tonato M: Gemcitabine and cisplatin versus mito-mycin, ifosfamide, and cisplatin in advanced non- small- cell lung cancer: a randomized phase III study of the Italian Lung Cancer Project. ... cisplatin-teniposide in patients withadvanced non- small- cell lung cancer. The European Organi-zation for Research and Treatment of Cancer Lung Cancer Cooperative Group. J Clin Oncol 1998, 16:2133-2141.7....
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Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf
... Non- small- cell lung cancer harbouring mutations in the EGFRkinase domain. Clin Transl Oncol 2010, 12:75-80.9. Gazdar AF: Activating and resistance mutations of EGFR in non- small- cell lung cancer: ... for the detection ofEGFR mutations in non- small- cell lung cancer. Clin Cancer Res 2009,15:3023-3028.13. Motoi N, Szoke J, Riely GJ, Seshan VE, Kris MG, Rusch VW, Gerald WL,Travis WD: Lung ... chain reaction for the detection of mutations and deletionsin the epidermal growth factor receptor gene: applications of thismethod for the diagnosis of non- small- cell lung cancer. Clin Chim...
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Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
... marker expression in tumor cells versus stromal cells in non small cell lung cancer. Clin Cancer Res 2007, 13:6649-57.24. World Health Organization: Histological Typing of Lung and PleuralTumours. ... according to NSCLC histology. Lung Cancer 2010.31. Donnem T, Al-Saad S, Al-Shibli K, Andersen S, Busund LT, Bremnes RM:Prognostic impact of platelet-derived growth factors in non- small cell lung cancer ... in the cytoplasm of most neo-plastic tumor cells and to a lesser extent expressed in the cytoplasm of normal epithelial cells in lung tissue.Based on m orphological cr iteria, infla mmatory cells(macrophages,...
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báo cáo hóa học: " Health state utilities for non small cell lung cancer" pot
... is the most com-mon and the most life-threatening form of cancer in Scot-land [2]. Lung cancer is also a major cause of deaththroughout the rest of the world [3,4]. Non- small cell lung cancer ... breast cancer. Br J Cancer 2006,95(6):683-90.17. Cancer Research UK [http://www.cancerresearchuk.org]18. Cancer Help [http://www.cancerhelp.org.uk]19. Association for International Cancer ... Staging of small cell and non- small cell lung cancer. University of Iowa Virtual Hos-pital; 1999. 6. Hopwood P, Stephens RJ: Symptoms at presentation for treat-ment in patients with lung cancer: ...
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Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
... cancers and the leading cause of cancer death world-wide (1). Lung cancer is generally classified into two histological types, small cell lung cancer (SCLC) and non small cell lung cancer (NSCLC). ... sensitivity to gefitinib in non- small cell lung cancer cell lines. Mol Cancer Res. 2006; 4(8): 521-8. 102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non- small- cell lung cancer ... EGFR-TKIs therapy. Key words: non- small cell lung cancer, EGFR, somatic mutation, tyrosine kinase inhibitor, gene amplification Introduction Lung cancer is one of the most common human cancers...
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Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
... chemotherapy resulted in further tumorshrinkage, with no additional toxicity, and gave the patient the possibility to undergo a lobectomy ratherthan a pneumectomy, with the obvious advantages of ... Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC),presenting with metastatic mediastinal lymph nodes, is challenging. Nevertheless, preoperative chemotherapy ... responses. Failure to obtain a response after the first few cycles should notautomatically discourage to continue treatment.IntroductionIn non- small cell lung cancer (NSCLC), mediastinallymphnode...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... models The total normal lung volume was defined as the total lung volume minus the primary GTV and volume of the trachea and main bronchi. From each lung DVH, the fol-lowing dosimetric factors ... V10 are the useful indicators for predicting SARP in NSCLC patients treated with concurrent chemotherapy and IMRT.Background Lung cancer is the leading cause of cancer- related deathin the urban ... CC: Dose-volume factors contributing to the incidence of radiation pneumonitis in non- small- cell lung cancer patients treated with three-dimensional conformal radiation therapy. Int J Radiat...
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Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx
... radiotherapy of non- small- cell lung cancer. Int J Radiat Oncol Biol Phys 2002, 52:382-389.16. Qiao X, Tullgren O, Lax I, Sirzén F, Lewensohn R: The role of radiotherapyin treatment of stage I non- small ... radiotherapyin treatment of stage I non- small cell lung cancer. Lung Cancer 2003,41:1-11.17. Shibamoto Y, Yukawa Y, Tsutsui K, Takahashi M, Abe M: Variation in the hypoxic fraction among mouse tumors ... withour prospective hypothesis-driven protocol.MethodsEligibility Criteria The eligibility criteria were as follows: histologi cally-confirmed non- small cell lung cancer (NSCLC)* Correspondence:...
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Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
... Stereotactic Body Rad iotherapy, Oligometastases, Non- Small Cell Lung Cancer Background Non- small cell lung cancer (NSCLC) is the leadingcause of cancer mortality in the United States [1].Patients ... Milano1*AbstractBackground: Standard therapy for metastatic non small cell lung cancer (NSCLC) includes palliative systemicchemotherapy and/or radiotherapy. Recent studies of patients with limited metastases ... progression and was postulated to be a poor prognostic factor in lung cancer. Similarly,Bradley et al. demonstrated the prognostic value ofGTV determined on planning CT scans to be associatedwith OS...
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Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
... GMM, Jeremic B:Report from the international atomic energy agency (IAEA)consultants' meeting on elective nodal irradiation in lung cancer: non- small cell lung cancer (NSCLC). Int J Radiat ... whentreating non- small cell lung carcinoma (NSCLC) to deliver 40 to 50 Gy to the uninvolved regional lymphnodes. Known as elective nodal irradiation (ENI), thistherapy is targeted to ipsilateral ... Organization forResearch and Treatment of Cancer, National Cancer Insti-tute of the United States, National Cancer Institute of Can- ada. J Natl Cancer Inst 2000, 93(3):205-216.7. Rosenzweig...
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Báo cáo khoa học: " Evalution of surface-based deformable image registration for adaptive radiotherapy of non-small cell lung cancer (NSCLC)" pptx
... of the elastic deformation (Nu) set to 0.3] theninterpolates the surface deformation to the entire volume to derive a volumetric deformation field. The deformationmap was then applied to the ... transformation of the middle image into the left image based on the mesh points on the surface of the GTV: note the distortion of the pulmonary structuresFigure 8Illustration of the consequences ... meshes. The contours of the macroscopic primary tumor in the planning CT and the follow-up CT are shown in red. Note the distortion of the vertebral body and the trachea without using meshes of these...
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Báo cáo khoa học: " Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases" docx
... stage I non- small cell lung cancer. Lung Cancer 1999, 26:137-142.23. Slotman BJ, Antonisse IE, Njo KH: Limited field irradiation inearly stage (T1-2N0) non- small cell lung cancer. RadiotherOncol ... (range: 1.6 to 16.4 %) and 5.3% (range: 1.2 to 14.3%), respectively.Yet, these volumes and the planning target volumes werestill small in comparison to the total volume of the lungsand, up to this ... were irradiated; with each of 33 patients, stage I non- small cell lung cancer (NSCLC) was subject to irradiation. The standard dose prescribed to the isocenter was30 Gy with an axial safety margin...
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Báo cáo khoa học: " Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer" pot
... as lung cancer. It is more convenient for the patients and reduces health care costs.This study reports our results on patients with medically inoperable, early stage, non- small cell lung cancer ... considered to have N1 diseaseclose to the primary lung tumor. In 19 cases (59%) the tumor was in the right lung. In 22 cases (69%) the tumorwas located in the upper lobes.Radiotherapy was ... purposes)Background The use of accelerated hypofractionated radiation therapyis an attractive option for patients with early stage non- small cell lung cancer (NSCLC) who are not surgical can- didates....
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Báo cáo khoa học: " Accelerated high-dose radiotherapy alone or combined with either concomitant or sequential chemotherapy; treatments of choice in patients with Non-Small Cell Lung Cancer" pps
... purposes)BackgroundWorldwide and in Europe lung cancer is the most com-mon cause of cancer related-death with an increasing inci-dence each year. The majority of patients has Non- Small Cell Lung Cancer (NSCLC) and ... stage I Nonsmall cell lung carcinoma. Cancer 2004,101:1623-1631.54. Belderbos J, Heemsbergen W, Hoogeman M, Pengel K, Rossi M, Leb-esque J: Acute esophageal toxicity in non- small cell lung can- cer ... Post-operative chemotherapy for non- small cell lung cancer: Asystematic review and meta-analysis. J Thorac Cardiovasc Surg2004, 128:414-419.39. The International Adjuvant Lung Cancer Collaborative...
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