can drugs cause bad skin

Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast docx

Ngày tải lên : 07/03/2014, 21:20

... 90-binding drugs: a ligand- independent approach to hormonal therapy of breast cancer. Clin. Cancer Res. 7, 2076–2084. 16. Workman, P. & Maloney, A. (2002) HSP90 as a new therapeutic target for cancer ... [22]. Though this study has focussed on mutations that cause an increased sensitivity to Hsp90 drugs, it is probable that increased resistance can also arise (e.g. through gain-of- function PDR mutations ... tumours [45]. Discussion This study is the ﬁrst to reveal that an increased sensitivity to Hsp90 drugs can arise with mutations to Hsp90 itself (Fig. 1) and with speciﬁc ABC transporter defects (Fig....

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Báo cáo khoa học: Identiﬁcation of preferred substrate sequences for transglutaminase 1 – development of a novel peptide that can efﬁciently detect cross-linking enzyme activity in the skin pot

Ngày tải lên : 23/03/2014, 06:20

... Journal compilation ê 2008 FEBS 5677 concentration. However, in the skin sections, there was no signiﬁcant TGase 2 activity because FITC-labeled T26 showed no signal (data not shown). To date, ... mouse skin sections. (A) FITC-labeled peptides (1 l M), pepK5 (upper) or pepK5QN (lower), were incubated with mouse skin sections in the presence of CaCl 2 or EDTA. TGase 1 activity in skin sections ... measured. Detection of in situ TGase 1 activity in mouse skin sections Fluorescence-labeled peptides (FITC-pepK5 and FITC- pepK5QN) were synthesized, and skin sections were pre- pared from wild-type and...

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bad drugs

Ngày tải lên : 02/04/2014, 17:48

... They can hurt you and your friends. If you do drugs, you are very stupid. They can hurt you and your friends. If you do drugs, you are very stupid. They can hurt you and your friends. If you do drugs, ... They can hurt you and your friends. If you do drugs, you are very stupid. They can hurt you and your friends. If you do drugs, you are very stupid. They can hurt you and your friends. If you do drugs, ... They can hurt you and your friends. If you do drugs, you are very stupid. They can hurt you and your friends. If you do drugs, you are very stupid. They can hurt you and your friends. If you do drugs, ...

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Hướng dẫn chi tiết cách tạo skin KIS 2011 add key file ko cần ngắt mạng potx

Ngày tải lên : 20/06/2014, 23:20

... ChooseKey_Desc = "Key file needed" [ConfigureWizard.ActivationChooseKey_Info] Bước 4 : Nạp skin vào và xem kết quả. Generated by Foxit PDF Creator â Foxit Software http://www.foxitsoftware.com...

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Báo cáo y học: "What can chronic arthritis pain teach about developing new analgesic drugs" ppt

Ngày tải lên : 09/08/2014, 06:22

... injury to chronic pain sustained in the absence of damage, one can then ask the following types of question: How much of chronic pain is caused by mechanisms that are initiated by acute pain processes ... clinical trial settings have the apparent limitation of only identifying drugs with mechanisms of action similar to already approved drugs, while screening out analgesics with completely new mechanisms ... NSAID activity. This circular process therefore may fail to detect drugs acting through non- opioid or non-NSAID mechanisms because these investi- gational analgesics might never advance beyond...

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Báo cáo y học: "Bone erosions in rheumatoid arthritis can be repaired through reduction in disease activity with conventional disease-modifying antirheumatic drugs." pot

Ngày tải lên : 09/08/2014, 08:22

... order of the radiographs. Erosion scores can range from 0 to 160. Joint space narrowing (JSN) scores can range from 0 to 120. Total radiographic scores can range from 0 to 280. Readers were allowed ... 34.0, 92.8 P b NS a Scores can range from 0 to 280, with higher scores indicating more joint damage. b Mann-Whitney U test. c Scores can range from 0 to 160. d Scores can range from 0 to 120. ... prescribed DMARDs using the Mann-Whitney U test. Statistical significance was defined as a P value less than 0.05. Significant variables in univariate analysis were entered simultaneously into...

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Báo cáo khoa học: "Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs?" ppt

Ngày tải lên : 09/08/2014, 09:22

... tomography (CT) scans in 40 non-cancer patients (age 65 and 75 years in 50% each) and 17 prostate cancer patients. Five of the younger, 7 of the older and 4 of the cancer patients had significant cardiac ... gynaecomastia and breast pain caused by bical- utamide in prostate cancer: a randomised controlled trial. Lancet Oncol 2005, 6:295-300. 8. Van Poppel H, Tyrrell CJ, Haustermans K, Cangh PV, Keuppens F, Colombeau ... randomized Scandinavian trial SPCG-7/ SFUO-3. Urology 2003, 61:145-151. 11. Chen KC, Peng CC, Hsieh HM, Peng CH, Hsieh CL, Huang CN, Chyau CC, Wang HE, Peng RY: Antiandrogenic therapy can cause coronary...

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Báo cáo y học: "Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing" potx

Ngày tải lên : 13/08/2014, 08:20

... statistical significance because of the small sample size, but it should not be ignored. Commentary Selenium supplementation in critically ill patients: can too much of a good thing be a bad thing? Daren ... (risk ratio (RR) 0.69, 95% confidence interval (CI) 0.59 to 0.82) [4]. However, selenium compounds can also be considered ‘pro- oxidative’. As the authors suggest, the pro-oxidant properties of selenite ... 2007, 31:109-118. 9. Heyland DK, Dhaliwal R, Day AG, Muscedere J, Drover J, Suchner U, Cook D; Canadian Critical Care Trials Group: REducing Deaths due to OXidative Stress (The REDOXS Study):...