calcitriol and vitamin d analogs

... the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analyses Study concept and design: CA and OB Acquisition of data: CA and OB Analysis and ... Jackson RD et al 2006 [13] - Randomized trial, controlled, double blinds - Randomized trial, controlled, double blinds - Mean follow-up 10 months - Vertebral fracture and long bone, and fall - ... Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: a randomized controlled trial Cerebrovasc Dis 2005, 20:187-192 53 Ceglia L: Vitamin D and...

Ngày tải lên: 19/06/2014, 08:20

... acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid and α-linolenic acid e Sum of arachidonic and linoleic acids b Age Dietary intake of omega-3, omega-6 fatty acids, vitamin D and risk ... intake and dietary intake of vitamin B12, alcohol and dietary intake of fat other than eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid e Sum of arachidonic and linoleic acids ... low-fat dairy products and margarines are fortified with vitamin D Otherwise the dietary intake of vitamin D would be lower Furthermore, men were not included in the study and there is gender difference...

Ngày tải lên: 11/08/2014, 16:22

... with dietetic and anthropometric variables Obesity 2009, 17:778-782 McGill A-T, Stewart JM, Lithander FE, Strik CM, Poppitt SD: Relationships of low serum vitamin D3 with anthropometry and markers ... Immunomodulatory effects of vitamin D in multiple sclerosis Brain 2009, 132:1146-1160 Rodríguez-Rodríguez E, Navia B, López-Sobaler AM, Ortega RM: Vitamin D in overweight/obese women and its relationship ... CA, Samuel MC, Rosenberg J, Talarico J, Hatch D; California Pandemic (H1N1) Working Group: Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California...

Ngày tải lên: 13/08/2014, 20:21

Ngày tải lên: 13/08/2014, 20:22

... Tây D ơng có xương đóng hộp Cá mòi Thái Bình D ơng có xương đóng hộp Cá hồi có xương đóng hộp Gạo sữa đậu nành có tăng cường thêm chất canxi Nước cam có tăng cường thêm chất canxi sinh tố D Sữa ... biến loại để trét Phô mai, chế biến thành lát mỏng Phô mai làm từ sữa gạn kem, 2% Bánh pút-đinh (pudding) sữa trứng Sữa chua (yogurt), nguyên chất Sữa chua, có trái đáy hủ Sữa chua đông lạnh, loại ... xanh (broccoli) Cam Mật đường đen (Blackstrap molasses) Cá khô, cá ốt-me (smelt) Bông hoa hiên (daylily flower) Bánh đậu tương lên men, nấu chín Cải Fat choy (tóc tiên), khô Đậu hủ miếng to, nửa...

Ngày tải lên: 20/07/2015, 23:47

... isolated and expanded, and the expression of PTEN was examined by western blotting (C) Colony was treated with VD3, and apoptosis was evaluated (D) *P < 0.05, **P < 0.01, (n = 3) participated in ... in the VD3-induced apoptosis in gastric cancer cells indicated that vitamin D induced PTEN expression through binding of VDR to the PTEN promoter Vitamin D upregulated PTEN through VDR VDR synergistically ... (2000) Vitamin D and prostate cancer Endocrinology 141, 5–9 Holick MF (2004) Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease...

Ngày tải lên: 22/03/2014, 21:20

... studies have documented an age-dependent decline in serum 25hydroxyvitamin D and 1,25-dihydroxyvitamin D, and this age-related decline steadily worsened with institutional placement, decreasing ... Vitamin D3 = cholecalciferol 25-hydroxyvitamin D3 = calcidiol 1,25-dihydroxyvitamin D3 = calcitriol 7-dehydrocholestrol (7-DHC) = Provitamin D3 Previtamin D3 = isomeric form of 7-DHC under UVB irradiation ... 5,6-trans -vitamin D3 Cholesterol Vitamin D3 Vitamin D3 Basal membrane Dermis DBP -D3 DBP DBP DBP -D3 DBP -D3 DBP Figure 4.2 - Photochemical synthesis of vitamin D3 in human skin (from Bodo Lehmann,...

Ngày tải lên: 28/03/2014, 23:20

... contributed to study design and concept and writing and editing of the manuscript VT: contributed to the study design and concept, writing and editing of the manuscript and provided financial ... supervised in study design, and was involved in drafting the manuscript VT carried out the initial conception and design of the study, supervised and assisted in laboratory techniques, and was involved ... analysis HB provided general supervision and was involved in drafting the manuscript GM provided samples, supervised in study design, and was involved in drafting the manuscript TZ provided samples,...

Ngày tải lên: 18/06/2014, 15:20

... blinded, within-subject randomised, active- and vehicle-controlled, repeated dose study, conducted at CPCAD, Nice, France No topical treatment had been applied for four weeks prior to admission and ... derived from the method described by KJ Dumas and JR Scholtz [2] For each subject, six test sites of 2-cm diameter were selected on predetermined lesions, and a circular adhesive device was placed ... animals were bled and sacrificed The serum levels of calcipotriol and BDP were analyzed and determined to be below the detection limit (data not shown) Discussion The objective of this study was to...

Ngày tải lên: 18/06/2014, 15:20

... present, and prevalence of diabetes VDR, vitamin D receptor; OR, odds ratio; CI, confidence interval DISCUSSION We examined the relationship between ApaI, BsmI, and FokI VDR polymorphisms and severe ... Characteristics of the study subjects according to the genotypes of the Apa I, Bsm I, and Fok I VDR polymorphisms VDR, vitamin D receptor; SD, standard deviation Table Genotype and allele frequencies ... studies involving the VDR, mostly the TaqI polymorphism and periodontal disease, have been conducted in different ethnic populations and settings [23,24], and a few studies have investigated the...

Ngày tải lên: 08/08/2014, 16:23

... which included daily oral doses of vitamin D3 between 500 IU and 1000 ID per day Vitamin D is now even sold over the counter Moreover, it is included in most commercial baby food products although ... and this was endorsed by many physicians" [9] This tradition was restricted to the coasts of England, Holland, and France [10] Industrialized cod liver oil production (as the sole source of vitamin ... irradiated ergosterin, was introduced into the market by E Merck AG, who produced between and kg of vitamin D2 per year Production increased after 1938 up to 40 kg but ceased in 1945 [19] and was...

Ngày tải lên: 08/08/2014, 21:20

... association was observed between individual VDR gene polymorphisms and the overall odds of hand OA However, the VDR aa genotype posed an almost doubled odds of symmetrical hand OA (OR = 1.93, 95% ... participated in the evaluation of reliability of radiographs' readings HR conceived of the study and participated in its design PLA conceived of the study and participated in its design and coordination ... Ann Rheum Dis 1989, 48:271-280 53 Sowers M, Lachance L, Hochberg M, Jamadar D: Radiographically defined osteoarthritis of the hand and knee in young and middle-aged African American and Caucasian...

Ngày tải lên: 09/08/2014, 07:20

... sodium phosphate, pH7.4 and 0.9% sodium chloride), the second antibody conjugated with horseradish peroxidase was added to incubate for one hour The ECL detection system (Millipore) was used and ... biotin-conjugated secondary antibody (2 μg/mL) was added to incubate at 300 rpm for 30 Finally 50 μL of streptavidin-Phycoerythrin was added to each well and mixed at 300 rpm for 10 After drying up and washing, ... presented in eight gels The expressional trends of A2M (D) , VDBP (E) and ApoAI (F) were calculated with DeCyder 6.5 software A2M is an up-regulated protein; VDBP and ApoAI are down-regulated proteins...

Ngày tải lên: 10/08/2014, 05:21

... they would have reduced skin production of vitamin D due to higher melanin content, coupled with reduced sunlight exposure Second, although milk in Ireland is fortified with vitamin D, both patients ... features in vitamin D deficiency related myopathy are the proximal distribution, the waddling gait, and pain and discomfort due to muscular effort Both cases demonstrated these findings clinically ... had limited intake of other dietary sources of vitamin D such as oily fish and eggs They also consumed unleavened breads, such as chapati, almost daily Unleavened bread contains phytic acid,...

Ngày tải lên: 11/08/2014, 00:23

... respective signal transduction pathways Several interactions between the vitamin D and oestrogen endocrine system have been described 1,25-Dihydroxyvitamin D3 (1,25-(OH) 2D3 ) and 17β-estradiol (E2) have ... these conditions (i.e centre edge angle and acetabular index) on the affected and non-affected sides were also compared with genotype In the DDH group, homozygosity for the Taq I Vitamin D receptor ... contributions BK and CD performed the molecular assays CD and CHWJ were involved in the conceptualisation of the study as well as defining the radiographic measurement methods RCS and AAF were involved in...

Ngày tải lên: 11/08/2014, 08:21

... VitD receptor (VDR) and VitD binding protein (DBP) have been identified that modulate the development of tuberculosis [96] The genotype tt (detected by Taq I digestion) is associated with decreased ... inclusion and again at and months after start of treatment Reduction in TBscore and sputum smear conversion rates did not differ among VitD and placebo treated patients Taken those data together ... and mature osteoclasts, and it inhibits OPG expression, which binds RANKL and prevents RANK mediated osteoclastogenesis [37] VitD deficiency causes the development of an imbalanced calcium- and...

Ngày tải lên: 12/08/2014, 13:22

... acquired funding for the SAGE and CAPPS studies TJH and CL conceived and acquired funding for the SLSJ study TJH also provided general supervision of the research group All authors read and approved ... participated in the conception and coordination of the BHS BAR and STW participated in the conception and coordination of CAMP ALK participated in the coordination of the SAGE study AB conceived and acquired ... (encoded by the CYP24A1 locus) In vitamin D target cells, 1α,25-(OH)2 D3 translocates to the nucleus and binds to the vitamin D receptor (VDR) The ligand/receptor complex binds vitamin D response...

Ngày tải lên: 12/08/2014, 14:20

... report J.A did the clinical survey, C.B did the SNP analysis, M.B built serum and DNA bank and did the vitamin D assays together with E.A who supervised also laboratory work and did functional ... SNPs indicated by ¶ were used to build haplotypes candidate genes was rather subjective, it turned out that some of the tested candidate genes are associated with both allergy and vitamin D metabolites ... conversion rate decreased with higher levels of 25-OH -D3 (Figure 3) Data handling and statistical analysis Clinical data and genotypes were all transferred to a SQL 2000 database and checked for completeness,...

Ngày tải lên: 12/08/2014, 16:20

... N,Nʹ-dicyclohexylcarbodiimide DCM Dichloromethane DMAP Dimethylaminopyridine DMEM Dulbecco’s Modified Eagle Medium DMSO Dimethyl Sulfoxide DOX Doxorubicin EPR Enhanced Permeation and Retention FBS Fetal Bovine Serum ... nanoparticles of biodegradable copolymers such as PLATPGS and PLGA-TPGS for controlled and targeted delivery of paclitaxel, employed as a model anticancer drug (Mu and Feng 2003; Zhang and Feng 2006; ... R 1983; Lloyd JB 1983) Its derivative with the antitumor drug doxorubicin was the first drug-conjugate design developed This was developed based on the Ringsdorf model and it entered the clinical...

Ngày tải lên: 16/10/2015, 15:36

... study compared effects of two vitamin D doses The daily dose of 1500 IU resulted in better blood glucose and, although did not absolutely decreased IR, did reduced IR increase for that period ... of vitamin D 1.1.1 Chemical nature and metabolism of vitamin D Vitamin D exists in two forms, Cholecalciferol (Vitamin D3 ) and Ergocalciferol (Vitamin D2 ) Vitamin D is converted to 25(OH )D in ... higher vitamin D doses to lower ones reduced IR and improved blood glucose in pregnant women with and without GDM in a number of studies However, those studies included both pregnant women with and...

Ngày tải lên: 11/05/2016, 08:56