bladder and renal cancer

... diagnosed urothelial cancers in men and up to 40% in women The risk of developing a urothelial malignancy in male smokers is increased two- to fourfold relative to nonsmokers and continues for 10 ... increase in both squamous and transitional cell carcinomas of the bladder Pathology Clinical subtypes are grouped into three categories: 75% are superficial, 20% invade muscle, and 5% are metastatic ... tumor within the bladder is based on the pattern of growth and depth of invasion: Ta lesions grow as exophytic lesions; carcinoma in situ (CIS) lesions start on the surface and tend to invade...

Ngày tải lên: 07/07/2014, 02:20

... T1, and T2 or greater lesions, tumors with alterations in p53, p21, and/ or RB have a higher probability of recurrence, metastasis, and death from disease Clinical Presentation, Diagnosis, and ... 80–90% of patients and often reflects exophytic tumors The bladder is the most common source of gross hematuria (40%), but benign cystitis (22%) is a more common cause than bladder cancer (15%) (Chap ... present A flexible endoscope is inserted into the bladder, and bladder barbotage is performed The visual inspection includes mapping the location, size, and number of lesions, as well as a description...

Ngày tải lên: 07/07/2014, 02:20

... surgery that requires appropriate preoperative evaluation and management The procedure involves removal of the bladder and pelvic lymph nodes and creation of a conduit or reservoir for urinary flow ... management (e.g., due to multicentric and frequent recurrences resistant to intravesical instillations); high-grade tumors (T1G3) associated with CIS; and bladder symptoms, such as frequency or ... detubularized bowel or an orthotopic neobladder Some 70% of men receive a neobladder With a continent reservoir, 65–85% of men will be continent at night and 85–90% during the day Cutaneous reservoirs...

Ngày tải lên: 07/07/2014, 02:20

... Carcinoma of the Renal Pelvis and Ureter About 2500 cases of renal pelvis and ureter cancer occur each year; nearly all are transitional cell carcinomas similar to bladder cancer in biology and appearance ... recur locally and to metastasize Metastatic disease is treated with the chemotherapy used in bladder cancer, and the outcome is similar to that of metastatic transitional cell cancer of bladder origin ... vinblastine, doxorubicin, and cisplatin (M-VAC); cisplatin and paclitaxel (PT); gemcitabine and cisplatin (GC); or gemcitabine, paclitaxel, and cisplatin (GTC) M-VAC was considered standard, but the toxicities...

Ngày tải lên: 07/07/2014, 02:20

... predisposes to renal cell carcinomas, retinal hemangioma, hemangioblastoma of the spinal cord and cerebellum, and pheochromocytoma Roughly 35% of individuals with VHL disease develop renal cell cancer ... for first-degree relatives Pathology and Genetics Renal cell neoplasia represents a heterogeneous group of tumors with distinct histopathologic, genetic, and clinical features ranging from benign ... (PDGF), and a number of other hypoxia-inducible proteins Inactivation of VHL leads to overexpression of these agonists of the VEGF and PDGF receptors, which promote tumor angiogenesis and tumor...

Ngày tải lên: 07/07/2014, 02:20

... transitional cell carcinoma of the renal pelvis, sarcoma, lymphoma, and Wilms' tumor All of these are less common causes of renal masses than is renal cell cancer Staging and Prognosis Two staging systems ... sedimentation rate 55 The standard evaluation of patients with suspected renal cell tumors includes a CT scan of the abdomen and pelvis, chest radiograph, urine analysis, and urine cytology If metastatic ... diagnosis of a renal mass includes cysts, benign neoplasms (adenoma, angiomyolipoma, oncocytoma), inflammatory lesions (pyelonephritis or abscesses), and other primary or metastatic cancers Other...

Ngày tải lên: 07/07/2014, 02:20

... Nelson EC et al: Renal cell carcinoma: Current status and emerging therapies Cancer Treat Rev 33:299, 2007 [PMID: 17329029] Sugano K, Kakizoe T: Genetic alterations in bladder cancer and their clinical ... the bladder: A systematic review and meta-analysis J Urol 171:561, 2004 [PMID: 14713760] Bibliography Advanced Bladder Cancer Meta-Analysis Collaboration: Neoadjuvant chemotherapy in invasive bladder ... factors Patients with zero, one or two, and three or more factors had a median survival of 24, 12, and months, respectively These tumors may follow an unpredictable and protracted clinical course It...

Ngày tải lên: 07/07/2014, 02:20

... neurogenic bladder and renal dysfunction are associated with SCI and statin treatment has been reported to protect against SCI, we investigated the efficacy of simvastatin for bladder hypertrophy and renal ... therapies, including statins, on bladder and renal functions is not known Therefore, this study investigates the therapeutic efficacy of simvastatin for restoring bladder and renal functions following ... MK and IS MK and AS wrote the manuscript AS, PCC, RKD, MB carried out animal and biochemical studies AS, MM, AGC, BRS, TCS performed histochemical studies JKO critically examined renal and bladder...

Ngày tải lên: 11/08/2014, 03:20

... neurogenic bladder and renal dysfunction are associated with SCI and statin treatment has been reported to protect against SCI, we investigated the efficacy of simvastatin for bladder hypertrophy and renal ... therapies, including statins, on bladder and renal functions is not known Therefore, this study investigates the therapeutic efficacy of simvastatin for restoring bladder and renal functions following ... MK and IS MK and AS wrote the manuscript AS, PCC, RKD, MB carried out animal and biochemical studies AS, MM, AGC, BRS, TCS performed histochemical studies JKO critically examined renal and bladder...

Ngày tải lên: 11/08/2014, 06:22

... common being breast cancer, prostate cancer, colorectal cancer, bladder cancer, and non-Hodgkin’s lymphoma (14) Incidentally discovered renal tumors are confined within the renal capsule (P2 or ... cell lines of renal, bladder, and prostate cancers, and a high proportion of primary malignancies of the genitourinary tract including kidney, ureter, bladder, prostate and testis cancers (3,10,14–28) ... great vessels and the kidney within Gerota’s fascia During the radical nephrectomy, the surgeon gains early control of the renal hilum and ligates and divides the renal artery and the renal vein...

Ngày tải lên: 11/04/2014, 10:28

... histological subtypes are hybrid oncocytic (50%) and chromophobe (34%) renal cell carcinomas Clear cell oncocytomas and papillary renal cell cancers are less frequently found [15] Radiographic ... over the scalp, forehead, face and neck, and with scattered lesions observed on the chest and back [1] Histologically, these were confirmed to be fibrofolliculomas and trichodiscomas, which are ... LI and ES were involved in the clinical management of our patient GW performed the literature review and prepared the manuscript LI and ES critically appraised the manuscript All authors read and...

Ngày tải lên: 11/08/2014, 12:20

... (Thr241Met) polymorphism and lung cancer risk Cancer Epidemiol Biomarkers Prev 2001; 10: 911-2 26 Chen S, Tang D, Xue K, et al DNA repair gene XRCC1 and XPD polymorphisms and risk of lung cancer in a Chinese ... polymorphism and risk of primary lung cancer Carcinogenesis 2003; 24: 1677-81 57 Cui Y, Morgenstern H, Greenland S, et al Polymorphism of Xeroderma Pigmentosum group G and the risk of lung cancer and ... associations between the XPA G23A polymorphism and lung cancer risk 3-3 ERCC1 polymorphisms and lung cancer risk The ERCC1 coding region is 1.1 kb long and comprises 10 exons This gene is located...

Ngày tải lên: 31/10/2012, 14:59

... medicine, industry, business and research, and for domestic and cosmetic purposes Physical characteristics and sources of exposure to artificial UV radiation Table UV index and Standard Erythemal Dose1 ... Artificial UV Radiation and Skin Cancer This standard was first established in 1985 and further modified in 1990, in 1995 and in 2002 A first amendment was added in 2004 and a second amendment ... UV, UVB and UVA (de Winter & Pavel, 2000) Today, lamps originally designed and intended for industrial applications (drying, polymerization) and which emit UV (UVA, UVB and UVC), visible and infrared...

Ngày tải lên: 14/02/2014, 21:20

... that surround the cancer as it arises Development and spreads — the cancer environment” — so that Our expanded knowledge of cancer- and patient- researchers can better understand the entire spec- ... analyzing cancer cells to evaluate the through tests and used to diagnose or monitor cancer genes, proteins and biological pathways that drive and its response to treatment cancer growth Cancer ... New Methods of Cancer Prevention, Diagnosis and open the door to entirely new methods of preventing, professional societies and the National Cancer Insti- diagnosing and treating cancer: tute (NCI)...

Ngày tải lên: 14/02/2014, 21:20

... u Lots of fruits and vegetables, and whole grain breads and cereals u Modest amounts of meat and milk products u Small amounts of fat, sugar, alcohol, and salt When you have cancer, though, you ... such as bleu cheese and Roquefort For more information about infection and cancer treatment, see Chemotherapy and You: Support for People With Cancer, a book from the National Cancer Institute You ... provide support for people with cancer and their families and friends The Cancer Support Community Dedicated to providing support, education, and hope to people affected by cancer Call: Visit: E-mail:...

Ngày tải lên: 14/02/2014, 21:20

... consideration 31 diagnosis and management of head and neck cancer 11 Laryngeal cancer 11.1 EARLY LARYNGEAL CAncer (Stage I and II) 11.1.1 Early Glottic cancer There is no good quality randomised controlled ... spread and/ or positive surgical margins 35 diagnosis and management of head and neck cancer 12 Hypopharyngeal cancer 12.1 Early HYPOPHARYNGEAL CANCER (Stage I and II) Early hypopharyngeal cancer ... the recognition and management of acute and late radiation toxicity 29 diagnosis and management of head and neck cancer 10 Treatment: palliation of incurable disease Head and neck cancer may be...

Ngày tải lên: 14/02/2014, 22:20

... Fig Relation between parity and risk of (a) early breast cancer and (b) late breast cancer Table Summary of the results on the relationship between breast cancer and reproductive factors according ... breast cancer in Hispanic and non-Hispanic white women Am J Epidemiol 148:683-92, 1998 26 McCredie M, Paul C, Skegg DCG, Williams S: reproductive factors and breast cancer in New Zealand Int J Cancer ... World Cancer Research Fund Food, Nutrition and the Prevention of Cancer: a global perspective Washington, DC: American Institute for Cancer Research, 1997 Stavraky K, Emmons S: Breast cancer...

Ngày tải lên: 05/03/2014, 17:20

... Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C http://www.nap.edu/catalog/12793.html Hepatitis and Liver Cancer: A National Strategy for Prevention and ... Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C http://www.nap.edu/catalog/12793.html Hepatitis and Liver Cancer: A National Strategy for Prevention and ... role of state and local chronic disease surveillance in describing the burden of morbidity and mortality related to chronic hepatitis B and hepatitis C and related liver cirrhosis and cancer, the...

Ngày tải lên: 06/03/2014, 01:20

... reserved Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C http://www.nap.edu/catalog/12793.html  HEPATITIS AND LIVER CANCER Knowledge and Awareness ... Data Hepatitis and liver cancer : a national strategy for prevention and control of hepatitis B and C / Heather M Colvin and Abigail E Mitchell, editors ; Committee on the Prevention and Control ... Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C http://www.nap.edu/catalog/12793.html  SUMMARY To increase knowledge and awareness about hepatitis B and...

Ngày tải lên: 06/03/2014, 01:20

... drinking, and esophageal cancer in Argentina Cancer Epidemiol Biomarkers Prev 1994; 3: 557-564 Rolon PA, Castellsague X, Benz M, Munoz N Hot and cold mate drinking and esophageal cancer in Paraguay Cancer ... and risk of squamous cell esophageal cancer in northern Italy Int J Cancer 2000; 87: 289-294 Tuyns AJ, Riboli E, Doornbos G, Pequignot G Diet and esophageal cancer in Calvados (France) Nutr Cancer ... definition and classification Since information about gastric cancer and NOC and their precursors was heterogeneous, sources of exposure were classified into two groups: nitrosamines and nitrites;...

Ngày tải lên: 06/03/2014, 02:21