... without the benefit of hindsight, by ensuring that the examiner assesses the invention through the eyes of the person skilled in the art, with the benefit of his common general knowledge The inventive ... of the claim in question is then construed, and the differences between the state of the art and the inventive concept of the claim are identified This then enables the examiner to approach the ... relating to Biotechnological Inventions in the Intellectual Property Office Assessing inventive step: Fulfilling a need 41 The fact that other workers were attempting to find recombinant methods of...
Ngày tải lên: 13/03/2014, 21:48
... losses in other domains [22] The role of leisure in maintaining or restoring psychological wellbeing in the presence of arthritis pain warrants further study Psychosocial approaches to managing ... psychosocial functioning and coping of mothers with chronic pain (including mothers with arthritis) to mothers without pain, with regard to their ratings of parenting efficacy There was a significant ... comparison of conventional pain coping skills training and pain coping skills training with a maintenance training component: A daily diary analysis of short- and long-term treatment effects J Pain 2006,...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... using the direct binding assay as described in Experimental procedures Inset: Linearized plot of the binding data for apoE(263–286) (symbols) shown in panel A The solid line represents the linear ... fraction in the presence of both apoE isoforms However, a greater increase in the ordinate maximum and area under the curve is obvious in the presence of the apoE4 isoform (Fig 7C, open symbols), indicating ... particular, the binding footprint for the apoE4 isoform, corresponding to 3.0 amino acids per phospholipid, is almost twofold greater than the apoE3 isoform (Table 2), suggesting these isoforms differ in...
Ngày tải lên: 08/03/2014, 09:20
Some aspects of American culture and society in the twentieth and twenty-first centuries through a number of selected short literary works
... another The grandmother held the floor most of the time from the beginning of the story in her decision where to go, in her introduction of the scenery along the journey While the father, the mother ... setting Technique has to with the structuring of the story into the plot so that the writer can convey the theme and the manipulating of the language in order to express the ideas of the writer in ... aftermath, led the American to the golden age of booming national prosperity with the highest standard of living in the history of the world economy, as indicated in the increase of the Gross National...
Ngày tải lên: 07/11/2012, 15:01
Formation of Aerobic Granular Sludge in a Continuous-Flow Reactor – Control Strategy for the Selection of Well-Settling Granular Sludge
... decided the control strategy for the selection of well-settling sludge Then, we applied the strategy to the formation of aerobic granular sludge in a continuous experiment In addition, the effect of ... granulation in a continuous-flow reactor We focused our attention on the controllable factors influencing the selection of well-settling sludge because the sludge selection is one of the most important ... and is influent feeding mode In Run 1, ammonia-rich wastewater was continuously fed from the bottom of the reactor, while the wastewater was intermittently fed (sequencing batch mode) in Run...
Ngày tải lên: 05/09/2013, 10:15
Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf
... cytokines, including IL-1b, TNF-a and IFN-c (B) Chemokines expressed in the joint recruit leukocytes into the joints In addition to functioning in cell trafficking, several chemokines have other biological ... concentrations of several chemokines Chemokines in the joints of patients Table Chemokines and chemokine receptors expressed in the joint of RA patients Systemic name CC chemokines CCL2 CCL3 ... et al Chemokines in the joints of patients CXC chemokines C and CX3C chemokines Interleukin-8 ⁄ CXCL8 (a ligand of CXCR1 and CXCR2) was the first chemokine identified to be involved in leukocyte...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: "Reactive Content Selection in the Generation of Real-time Soccer Commentary" pdf
... development of the game situation In the Figure 5, we have illustrated this in the same way we did for the case of interruption The left hand side of the solid line is lower than that of the dotted ... completely uttered The right part of the dotted line is lower than that of the solid, because the importance of the second utterance decreases over time when waiting interruption : with interruption ... Thus, the sum of the importance of the uttered propositions can no longer be used to access the system's performance Instead, the area between the lines and the horizontal axis indicates the total...
Ngày tải lên: 20/02/2014, 18:20
Báo cáo khoa học: Structural and functional aspects of unique type IV secretory components in the Helicobacter pylori cag-pathogenicity island potx
... presence of Cu(II), the protein shows the presence of the ion coordinated in a small cavity of the surface at the polar opposites of each monomer, close to another dimer present in the crystal packing ... of the interactions that were assumed to involve Cag proteins [16,17] These findings, combined with previous analysis on single components, have allowed the proposal of preliminary models of the ... thus supporting the idea that it might be involved in the translocation as a putative effector protein rather than being a component of the T4SS apparatus Finally, interaction studies indicated...
Ngày tải lên: 06/03/2014, 00:21
Báo cáo khoa học: Hydrogen bond residue positioning in the 599–611 loop of thimet oligopeptidase is required for substrate selection pdf
... The substrate also maintained its relative position in the active site during the simulation These data not preclude the existence of other possible conformations further away from the starting ... 604, 611) in the loop, particularly Gly603, in maintaining the plasticity of the active site and the full range of function of TOP Most recently [30], potential new substrates adhering to the size ... [0.31] the end of the simulation, despite having a close prox˚ imity between Tyr hydroxyl groups (e.g 2–3 A) and the substrate in the initial model In addition to reducing the flexibility of the...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: "Lexical Selection in the Process of Language Generation" ppt
... nonpropc~itional) slots in input frames; The history of processing, structured Mong the lines of the episodic memory oWaa~zat~on suggested by Kolodner (1984) and including the feedback of the results of actual ... contributing factors for selecting one verb over the other;, (I) the intended perspective of the situation, (2) the emphasis of one activity rather than another, (3) the focus being on a particular individual, ... outside the context of an utterance The selection of closed-class items, therefore, comes as a result of the use of the various control heuristics that guide the process of generation In other words,...
Ngày tải lên: 24/03/2014, 02:20
báo cáo hóa học: " Application of a hybrid wavelet feature selection method in the design of a self-paced brain interface system" pptx
... same as the size of the training IC feature sets This was done by randomly selecting epochs from the NC training set Results In this section, we present our offline analysis of the data of the four ... from Table 2) The blue line shows the fitness of the classifier as a function of the number of top features We began by training and testing the classifier using only the feature with the highest ... learning, all of the beneficial properties of linear classification methods, such as simplicity, are maintained, however, the overall classification is nonlinear in the input space, since the...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo hóa học: "A new low-complexity angular spread estimator in the presence of line-of-sight with angular distribution selection" pptx
... argue that the building of the LUT using the considered steps requires a lot of time and an accurate resolution of the integral in (5) However, the LUT is computed once for all off-line and would ... eigenvalues, but by the product of the characteristic matrix and the eigenvectors En The estimated AoAs are then the arguments of the complex roots of the obtained pseudospectrum One drawback of the extended ... test the envelope of the fading signal for Rician statistics and then to estimate the K-factor In [22], the K-factor estimator is based on statistics of the instantaneous frequency (IF) of the...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo lâm nghiệp: "Relative efficiency of alternative methods to evaluate wood stiffness in the frame of hybrid larch (Larix × eurolepis Henry) clonal selection" potx
... faces in 1996, to avoid compression wood being normally maximum in the Northeast part of the trunk (the dominant winds blow from the Southwest in Belgium) These 14-year-old trees were felled in the ... selection using indirect method (9% instead of 11.5% – Tab IX) Meanwhile, the lower estimate of gain slightly affects the final selection of the clone: in this sample (Tab X) to of the first clones ... between the opposite radial faces of the same ring, in the same orientation (North and South): measurements were carried out in the heartwood, and in the sapwood The next step was the sawing of each...
Ngày tải lên: 08/08/2014, 01:22
Báo cáo khoa học: "Some aspects of phytohormonal participation in the control of cambial activity and xylogenesis in tree stems" pot
... with the breaking of cambial dormancy (Little and Wareing, 1981Moreover, ABA content increases again in reactivating cambium, for example, in the trunk of Pinus contorta (Savidge and Wareing, ... inactivation of auxin receptor and carrier proteins Later on, the breaking of rest may occur when the conditions of active membrane trans- port are regained Is abscisic acid (ABA) involved in the regulation ... applied to the lower and upper sides of an inclined stem, respectively Reports concerning the intervention of other phytohormones in this process are somewhat conflicting Several observations indicate...
Ngày tải lên: 09/08/2014, 02:21
Báo cáo khoa hoc:" On the use analysis of animal models in the of selection experiments" pdf
... procedure of data splitting was implemented, first cumulating increasingly larger numbers of generations from the beginning of the experiment (analysis I), and then having separate groups of consecutive ... that of h Inferences are influenced by the amount of data available and the assumed type of a priori distribution of the variance components, as shown in the example in Sorensen et al [15] In this ... out for a limited number of generations, and the main interest is to evaluate the effect of selection on the means of the selected populations On the other hand, long-term selection experiments...
Ngày tải lên: 09/08/2014, 18:21
báo cáo khoa học: "Note Selection for increased and decreased total number of young born in the first three parities in mice" doc
... occurrence and the total number of lambs born per ewe over the first three lambings All these results suggest that indirect selection for high fertility in the L- line may have been opposing the selection ... litters below the control line That result was attributed to an effect of overloading in the uterus caused by shorter litter intervals combined with large litter size in the selected line Results ... (1981) observed an increased regularity of the cycle in a line of mice in which litter size was improved, whereas the line selected for small litter size showed a high percentage of irregular cycles...
Ngày tải lên: 09/08/2014, 22:22
Báo cáo y học: "Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature" pot
... EFV monotherapy at the time of therapy interruption selected the K103N mutation, which persisted as the prevalent quasispecies for over years of continual viral replication, in the absence of selective ... al reported on the persistence of K103N mutation after EFV interruption in patients failing to EFV-containing regimens, documenting variable decay kinetics for the K103N containing quasispecies ... transcriptase inhibitor; NVP, nevirapine; PI, protease inhibitor Competing interests The authors declare that they have no competing interests Consent Written informed consent was obtained from the patient...
Ngày tải lên: 11/08/2014, 14:21
báo cáo khoa học: " Selection of reference genes for quantitative real-time PCR expression studies in the apomictic and sexual grass Brachiaria brizantha" ppt
... geometric mean of the expression values of the set of the control genes tested The lower the M value, the more stably expressed the gene is Also, the program enables the exclusion of the most unstable ... region of the gene The M value for both sets of primers was the same, showing that the amplification region had no influence on the expression stability Although the difference in the M value of the ... present in more than 300 angiosperm species [10] and is being investigated by many groups due to the biotechnological interest of controlling the process of cloning through seeds The occurrence of...
Ngày tải lên: 12/08/2014, 03:20
báo cáo khoa học: " Complete plastid genome sequences suggest strong selection for retention of photosynthetic genes in the parasitic plant genus Cuscuta" ppt
... M: Loss of all ndh genes as determined by sequencing the entire chloroplast genome of the Black Pine Pinus thunbergii Proceedings of the National Academy of Sciences of the United States of America ... contains a portion of the 5' end of ycf1 Two segmental inversion events are observed in C exaltata One inversion occurs from trnV-UAC to psbE in the LSC region, the other in the SSC encompassing ... free-living seedlings may explain the need for an intact photosynthetic apparatus in this parasitic lineage Use of RuBisCo for lipid biosynthesis may also explain retention of rbcL in other holoparasite...
Ngày tải lên: 12/08/2014, 05:20