biomedical applications of metal containing luminophores

... their scores on the arm section of the Chedoke-McMaster (CM) Stroke Assessment Scale A CM score of represents complete paralysis, and a score of indicates a trace level of elbow or shoulder movement ... session consisted of 10 reaches to each of five targets at different locations in the workspace (1 thru in Figure 1C,D) for a total of 50 movements for both training groups Page of 13 (page number ... arm The hand piece consists of a trough for the forearm and a cm diameter cylinder placed in the palm of the user's hand Regardless of whether the user was capable of grasping the cylinder, two...

Ngày tải lên: 19/06/2014, 10:20

... absorption of fats and carbohydrates [5] In spite of their widespread use and the lack of credible reports regarding adverse effects, controversy has existed regarding the safety of bitter orange ... and is not a constituent of C aurantium Because of the known cardiovascular effects of nor-epinephrine and ephedrine, it has generally been assumed that consumption of p-synephrine and bitter ... increases in heart rate and blood pressure [8-11] The purpose of this study was to determine the effects of the acute administration of a product containing caffeine from guarana, p-synephrine from C...

Ngày tải lên: 25/10/2012, 11:10

... internal diameter of 0.2 m and a height of 0.8 m (effective volume of 20 L) The ozonation system received sludge withdrawn continuously from the end of the anoxic tank When the amount of sludge reached ... into the system The characteristics of the influent wastewater were as follows: 160–200 mg/L of SS, 55–80 mg/L of TOC, 45–55 mg/L of T-N, and 4.0–5.5 mg/L of T-P In this study, four different ... Concentration of each type of phosphorus in the influent and effluent of the phosphorus adsorption column The small graph at the right shows the breakthrough point (PO4-P concentration: mg/L) of the...

Ngày tải lên: 05/09/2013, 09:38

... of 0.4 mL of blank blood and 0.4 mL of IS- containing pentane solution in a glass vial with a Teflon-septum screw cap, which has been cooled with ice, and vortex-mixed for s; a 3-µL aliquot of ... described above The 5–6 vials containing different concentrations of the analyte are prepared to construct each external calibration curve, consisting of the concentration of an alkyl nitrite on the ... erythrocytes Therefore, the measurements of inorganic nitrite in blood seem useless for assessment of toxicity of alkyl nitrites The most useful indicator of alkyl nitrite poisoning is methemogloblin...

Ngày tải lên: 18/10/2013, 00:15

... TIC and mass chromatograms; (b) an EI mass spectrum of the t-BDMS derivative of EMPA; (c) a CI mass spectrum of the same derivative of EMPA data of animals According to the reports by the US army ... clarifying the purpose of its use are required VX and its decomposition products d) Upon the use of t-BDMS derivatization of EMPA, the final solution containing a large amount of the derivatization ... to dryness under a stream of nitrogen gas at room temperature e iii The residue is dissolved in 100 µL of the dichloromethane solution of DAEMO (IS solution); a 1-µL of it is injected into GC/MS...

Ngày tải lên: 18/10/2013, 00:15

... conditions The peaks of ∆9-THC (22.2 min), CBD (20.6 min) and CBN (23.2 min) are separated well; but the peak of CBC may overlap that of CBD When the dried cannabis is analyzed, the peaks of cannabinoids ... compound and IS are eluted with mL of n-hexane/ethyl acetate (4:1) containing % acetic acid and evaporated to dryness under a stream of nitrogen iii Derivatization-1 One of the above dry residues is ... 2.4 Mass spectra of the methyl ester plus TMS and TMS derivatives of ∆9-THC-11-oic acid The Substance Abuse and Mental Service Administration (SAMSA) in USA set the cutoff value of ∆9-THC-11-oic...

Ngày tải lên: 24/10/2013, 19:15

... low levels of morphine starting from a large amount of a specimen cannot be a proof of the intake of the drug The level of morphine in urine of healthy subjects determined by GC/MS was reported ... analysis is made by the comparison of the retention time of a peak of a specimen with that of the authentic standard and also by the confirmation of the absence of such a peak in a blank specimen ... than the cutoff level can be detected in some urine samples of subjects who have eaten a food containing poppy seeds [9] It should be noted that an amount of codeine comparable to that of morphine...

Ngày tải lên: 24/10/2013, 19:15

... 0.2-mL volume of the supernatant solution is transferred to a new polypropylene tube of the same type, followed by addition of 0.5 mL of concentrated sulfuric acid f and 0.5 mL of mesitylene ... volume of the supernatant solution is transferred to another polypropylene tube of the same type, and 0.5 mL of concentrated sulfuric acid f is added to the solution slowly A 0.5-mL volume of mesitylene ... ratio of nitrate to IS obtained from a test specimen is applied to the calibration curve to calculate its concentration ii Analysis of nitrite i A 0.2-mL volume of a test specimen and 0.1 mL of...

Ngày tải lên: 24/10/2013, 19:15

... interfered with by the coexistence of high concentrations of CO-Hb [6] As low as about 0.2 % of Met-Hb can be measured accurately However, when high concentrations of sulfhemoglobin (SHb) may interfere ... accurate determination of methemoglobin in blood containing carboxyhemoglobin Forensic Sci Int 17:177–184 7) Sato K (1983) A method for determination of methemoglobin in blood containing carboxyhemoglobin ... 0.5-mL volume each of distilled water is added To cuvettes C and D, a 0.5-mL volume each of % potassium ferricyanide solution is added vi To cuvettes A and C, a 3-mL volume each of 40 mM phosphate...

Ngày tải lên: 24/10/2013, 19:15

... However, in Japan, such criteria set by official institutions are not available for drugs of abuse Upon judgements of analytical data, the idea of cutoff values should be adopted with reference ... confirmation of a target compound is usually achieved by agreement of its mass spectrum with that of the authentic standard Since, with simultaneous use of a deuterated IS, a mass spectrum of a target ... estimate the cause of death, time of death and time after drug use, using the ratio of cocaine to BE and the brain-to-blood ratios of cocaine and BE The ratios only give rough estimation of them References...

Ngày tải lên: 29/10/2013, 01:15

... ng IS and one of various concentrations of pentazocine to each vial containing mL of blank whole blood or urine and mL distilled water, followed by the above procedure The number of different ... eluted with mL of chloroform/ethanol (9:1) into a glass vial A small amount of upper aqueous layer is carefully removed by aspiration with a Pasteur pipette The organic layer (chloroform) is evaporated ... added to mL of whole blood or urine M NaHCO3: a 8.4-g aliquot of NaHCO3 is dissolved in distilled water to prepare 100 mL solution Chloroform/ethanol (9:1, v/v): a 100-mL volume of the mixture...

Ngày tải lên: 29/10/2013, 02:15

... acetone/chloroform (4:1, v/v); (B) chloroform/methanol/n-hexane (4:2:1, v/v) Assessment of the method The Rf values of LSD were 0.29 with the (A) solvent system and 0.55 with the (B) system The colors of ... solutions are combined After the pH of the solution is adjusted to 8.5, the solution is extracted with an appropriate amount of chloroform four times The combined chloroform extract is evaporated to ... TLC or LC, and extracted with chloroform The resulting residue is subjected to analysis by the direct inlet method of EI-MS Analytical conditions Any type of an MS instrument can be used; electron...

Ngày tải lên: 08/11/2013, 01:15

... monitored) The mass spectra of TFA derivatives of MDMA and its three metabolites obtained from the urine specimen are shown in > Fig 7.5 For the proof of the use of MDMA, detection of MDA along with MDMA ... stream of nitrogen and reconstituted in 0.1 mL of DPM (IS) solution A 1-µL aliquot of it is injected into the GC/MS system with a DB-17MS systemk i Assessment of the methods EI mass spectra of TFA ... proof of MDMA use, detection of MDMA and its metabolite MDA is being generally performed for urine specimens In this chapter, the procedures for GC/MS and LC/MS analyses of MDAs in the forms of...

Ngày tải lên: 08/11/2013, 01:15

... amounts of methanol; a 10–20 µL aliquot is spiked into mL of a whole blood or urine specimen M NaHCO3 solution: 8.4 g of NaHCO3 is dissolved in distilled water to prepare 100 mL solution Chloroform/methanol ... eluted with mL of chloroform/methanol (9:1) into a glass vial v A small amount of upper aqueous layer is carefully removed by aspiration with a Pasteur pipette The organic layer (chloroform) is evaporated ... analyzed for IS from to 12 of retention time vii A calibration curve is constructed by adding various concentrations of PCP and 100 ng IS to the vials containing mL of blank whole blood or urine...

Ngày tải lên: 08/11/2013, 01:15

... mg/mL solution of the free form of chlorpromazine, the amount of chlorpromazine hydrochloride to be dissolved in mL methanol is calculated as follows mg (MW of the free form 318.9 MW of the salt ... amount of IS and various concentrations of a target compound are added to mL each of blank whole blood or urine, and processed as above At least vials containing different concentrations of the ... elution with mL of chloroform/acetonitrile (8:2) The upper aqueous layer of the eluate is removed with a Pasteur pipette; the organic phase is evaporated to dryness under a stream of nitrogen The...

Ngày tải lên: 15/12/2013, 12:15

... volume of urine or blood, 0.05 mL IS and 0.5 mL of M NaOH are placed in a 15-mL volume glass centrifuge tube with a ground-in stopper and mixed well, followed by addition of mL of the mixture of ... specimen to obtain a residue containing butyrophenones The residue is dissolved in 0.1 mL of the mobile phase of HPLC or LC/MS For HPLC-DAD and LC/MS, 50 and 20 µL of the above solution are injected, ... the aqueous phase is again washed with mL of the mixture of n-hexane/isopropanol by shaking it for 30 s After centrifugation at 600 g for min, 1.2 mL of the lower aqueous phase is transferred...

Ngày tải lên: 15/12/2013, 12:15

... tentative identification of drugs, a UV absorbance spectrum can be measured together with the confirmation of coincidence of retention time of a test peak with that of an authentic compound Although ... evaporated to dryness under a stream of nitrogen The residue is dissolved in 0.5 mL of each mobile phase; a 5-µL aliquot of it is injected into HPLC for analysis Assessment of the method > Figure 3.3 shows ... the mobile phase (B) With the use of the Eclipse XDB-C8 column, the peak top of nortriptyline (D) could be separated from that of amoxapine (E), but major parts of their peaks could not be separated...

Ngày tải lên: 15/12/2013, 12:15

... application of a crude specimen without any prior deproteinization process “Internal surface reversed phase column” is one of the columns of this type In this section, a method of LC/MS analysis of triazolam ... 1-mL volume of plasma is mixed with mL of solution A in a 4.5-mL volume glass vial; 20 µL of it is injected into LC/MSj ii Urine specimen A 1-mL volume of urine is mixed with 50 µL of M sodium ... be achieved; the peak of tofisopam showed tailing The separation of other drugs was relatively good The retention times, molecular weights and principal mass spectral ions of benzodiazepines are...

Ngày tải lên: 15/12/2013, 12:15

... stream of nitrogen vii The residue is dissolved in 100 µL of the mobile phase; a 10-µL aliquot of it is injected into HPLC i ii Extraction with a Sep-Pak C18 cartridge [1] i A 1-mL (or g) aliquot of ... with 10 mL distilled water and eluted with mL of dichloromethane/methanol (9:1) vi After removal of a small amount of the upper layer (aqueous phase) of eluate with a Pasteur pipette, the organic ... day of admission) and chloride (Cl), 151 mEq/L g The half-life of bromisovalum was 12.6 h; that of bromide 92.7 h The consciousness levels were in good parallel with blood concentrations of bromisovalum...

Ngày tải lên: 15/12/2013, 12:15