biochemistry in the service of the state
Tài liệu MELANOMA - FROM EARLY DETECTION TO TREATMENT docx
Ngày tải lên :
18/02/2014, 04:20
... as in 50 individuals [2-3] The incidence of melanoma varies according to the geographical origins of the population and the extent of sun exposure In Australia and United States, an incidence of ... lating the transcriptional up-regulation of these proteins and inducing maturation of the melanosomes [43] This ultimately results in increased eumelanin production and darkening of the skin ... potential of melanoma by increasing the expression of invasion-promot‐ ing integrins [22-23] Presence of BRAF mutations in benign and dysplastic nevi supports the hypothesis that activation of the...
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Methamphetamine Addiction From Basic Science to Treatment pptx
Ngày tải lên :
06/03/2014, 09:21
... 100,000 during the same time period The use of MA/amphetamine increased within certain southern states of the United States, as well, with the rate in Georgia going from in 1992 to 77 in 2005 (SAMHSA, ... understanding of the impact of MA on a user’s brain, which is essential if one is to fully appreciate the allure of the drug and the difficulties inherent in initiating and maintaining abstinence ... for the status of legislation in each state, see The Office of National Drug Control Policy, Pushing Back against Meth: A Progress Report on the Fight against Methamphetamine in the United States,...
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Addictions – From Pathophysiology to Treatment Edited by David Belin pdf
Ngày tải lên :
16/03/2014, 21:20
... Two-link heterogeneous chain schedules of reinforcement In this procedure completion of the first link of the chain, designated as the seeking link, results in access to the second link, or taking ... random interval (RI) schedule with the first seeking lever press occurring after the RI has elapsed terminating the first link of the chain; this results in retraction of the seeking lever and insertion ... insertion of the taking lever to initiate the second link One press on the taking lever results in the presentation of the reinforcer followed by a time-out period Thereafter, the seeking lever is reinserted...
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Football Traumatology Current Concepts: from Prevention to Treatment doc
Ngày tải lên :
24/03/2014, 02:21
... bursts of activity are required, including jumping, kicking, tackling, turning, sprinting, changing pace, and sustaining forceful contractions to maintain balance and control of the ball against ... monitored in co-operation with the coaching staff with the aim of returning to play as quickly as possible in case of injury The beneficiaries of the screening process are both the club and the individual ... this type of footwear during running alter both the correct mobility of the hindfoot when the heel strikes the ground and the function of the subtalar joint The physiological movements of the forefoot...
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EVALUATION OF CAPACITY TO CONSENT TO TREATMENT AND RESEARCH doc
Ngày tải lên :
29/03/2014, 00:21
... that in the opinion of the court in a proceeding to appoint or confirm authority of a health care representative, or in the opinion of the principal’s attending physician, a principal lacks the ... used in many statutes Indeed, in the example used above, we saw that ‘‘ ‘incapable’ means that in the opinion of the court or in the opinion of the principal’s attending physician’’ so that the ... person is in court (on a criminal charge), and it involves interests that go beyond those of the person being examined There is a need to balance the interests of the state (in carrying out justice)...
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Báo cáo sinh học: "The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" pdf
Ngày tải lên :
18/06/2014, 19:20
... activation of caspase (an apoptotic indicator) was observed following any of these above treatments in any of the cell lines tested (data not shown) Therefore, inhibition of the activity of glycolytic ... than those of proteins involved in signal transduction pathways Thus, the use of such inhibitors may be beneficial in combination therapy as enhancers of the action of current chemotherapeutic ... for the determination of the rates of aerobic glycolysis in the presence (open bar) or absence (closed bar) of glutamine The rates of aerobic glycolysis were also determined after the addition of...
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báo cáo hóa học:" The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" ppt
Ngày tải lên :
20/06/2014, 03:20
... activation of caspase (an apoptotic indicator) was observed following any of these above treatments in any of the cell lines tested (data not shown) Therefore, inhibition of the activity of glycolytic ... than those of proteins involved in signal transduction pathways Thus, the use of such inhibitors may be beneficial in combination therapy as enhancers of the action of current chemotherapeutic ... for the determination of the rates of aerobic glycolysis in the presence (open bar) or absence (closed bar) of glutamine The rates of aerobic glycolysis were also determined after the addition of...
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báo cáo hóa học:" From HIV diagnosis to treatment: evaluation of a referral system to promote and monitor access to antiretroviral therapy in rural Tanzania" doc
Ngày tải lên :
20/06/2014, 08:20
... the HIV treatment clinics The cost of covering the return fare to the HIV treatment clinic in this setting was in the region of US$25-30 per patient per year, corresponding to a fraction of the ... successfully linked to the HIV clinic, in order to assess the effectiveness of the VCT clinic as a "gatekeeper" to the HIV treatment programme The "Tumaini" programme, now operating under the name ... assigned by the HIV clinic on this section, referral data could be subsequently linked to the data recorded in patients' HIV clinic files The remaining part of the form also included the patient's...
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báo cáo hóa học:" A lifeline to treatment: the role of Indian generic manufacturers in supplying antiretroviral medicines to developing countries" pptx
Ngày tải lên :
20/06/2014, 08:20
... block international trade in generic medicines when they are suspected of infringing patents in the countries through which they transit These types of Page of border measures blocked medicines ... the prominence of Indian generic manufacturers in the supply of antiretroviral medicines to developing countries Since 2006, Indian-produced generic ARVs have accounted for more than 80% of the ... at a time when the prospects of ART scale up are already cloudy New WHO guidelines recommending early initiation of ART [22] will result in increased Waning et al Journal of the International...
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DYSLIPIDEMIA FROM PREVENTION TO TREATMENT potx
Ngày tải lên :
27/06/2014, 13:20
... of heart ventricles .The above findings all seem to indicate that rather than being an insulincorrelated factor BMI may well be implicated in lipid alteration On the other hand, the presence of ... to coexisting (29) insulin resistance the negative effect of androgen observed on lipid profile In this case, the low incidence of insulin resistant subjects in a population may explain this unexpected ... safety of atorvastatin in the prevention of cardiovascular end points in subjects with type diabetes: the Atorvastatin Study for Prevention of Coronary Heart Disease Endpoints in non-insulin-dependent...
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Báo cáo y học: " Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden" docx
Ngày tải lên :
09/08/2014, 08:23
... analysis of etanercept and infliximab comparing groups of patients starting either TNF-blocking drugs in combination with MTX or as monotherapy is shown in Table The number of patients initiated ... differences in costs of the TNF-blocking agents did not induce a selection bias Also, the possibility for termination bias was investigated by examining disease activity of patients terminating therapy ... primarily to the design of the registration scheme and should not be interpreted as certainty of the termination reason Thus, results regarding cause of treatment termination must be interpreted...
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Báo cáo khoa học: " Does Intensity Modulated Radiation Therapy (IMRT) prevent additional toxicity of treating the pelvic lymph nodes compared to treatment of the prostate only?" ppt
Ngày tải lên :
09/08/2014, 09:22
... sum of both structures was defined as the clinical target volume (CTV) The CTV-1 was the prostate including seminal vesicles and the CTV-2 was the prostate and base of the seminal vesicles The ... 3D margin of 10 mm resulting in the planning target volume (PTV-1), to posterior the margin was limited to mm A 3D margin of mm was added to the CTV-2 resulting in the PTV-2, overlap with the rectum ... of the planning CT and MRI, for target volume definition, treatment planning and plan evaluation The prostate and seminal vesicles were contoured in the planning CT and the planning MRI and the...
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báo cáo khoa học: "Apoptosis in cancer: from pathogenesis to treatment Rebecca SY Wong" pps
Ngày tải lên :
10/08/2014, 10:21
... treatment strategies used in targeting the Bcl-2 family of proteins include the use of therapeutic agents to inhibit the Bcl-2 family of anti-apoptotic proteins or the silencing of the upregulated anti-apoptotic ... improvement in survival in these patients [66,67] Other examples included in this category are the small molecule inhibitors of the Bcl-2 family of proteins These can be further divided into: 1) ... originally observed at the chromosomal breakpoint of the translocation of chromosome 18 to 14 in follicular non-Hodgkin lymphoma [26] There are two main groups of the Bcl-2 proteins, namely the...
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Báo cáo y học: "soriatic arthritis: Pathogenesis and novel immunomodulatory approaches to treatment" doc
Ngày tải lên :
11/08/2014, 10:23
... spurred interest in using TNF-α inhibitors in PsA Currently there are three TNF-α inhibitors available: 1) etanercept, a fusion protein consisting of a dimer of the extracellular portion of the type ... It interacts with its ligand, intercellular adhesion molecule (ICAM-1), in ways that may be relevant to the pathogenesis of psoriasis including: stabilizing the binding of antigen-presenting ... many of the activities of which overlap with TNF, has been suggested to be of potential importance in the pathogenesis of joint and other inflammation [82] Anakinra (IL-1ra) a homologue of the...
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Báo cáo y học: "Longitudinal changes in HIV-specific IFN-γ secretion in subjects who received Remune™ vaccination prior to treatment interruption" pot
Ngày tải lên :
11/08/2014, 10:23
... stimulus The height of the bar is the cumulative magnitude of the response to the peptide panel tested The number over the bar is the number of peptides in the panel recognized at that time point The ... healthy HIV infected adults in the chronic phase of infection were enrolled in March 2000 in this proof of concept trial The research conformed with all ethical guidelines of the authors' institutions ... to the second time point tested (data not shown) Furthermore, comparison of the magnitude of the change in IFN-γ responses from the first to the second time point differed significantly in these...
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Báo cáo y học: "Recurrence of suicidal ideation due to treatment with antidepressants in anxiety disorder: a case report" docx
Ngày tải lên :
11/08/2014, 10:23
... carried out in order to expand the understanding of the phenomenon of suicidal ideation due to SSRI medication These studies pointed out that regarding the risk of developing suicide acts, the new ... http://www.jmedicalcasereports.com/content/1/1/166 On the other hand, many studies confirm the reciprocal connection between the increased use of antidepressants and the decline of suicide For example, in a study conducted in Scandinavia, ... that for the society as a group, the use of antidepressants is beneficial Nevertheless, for certain individuals, these medicines could cause suicide ideation and put them in great risk [12] Therefore,...
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Báo cáo y học: " Lower lid entropion secondary to treatment with alpha-1a receptor antagonist: a case report" pdf
Ngày tải lên :
11/08/2014, 11:23
... shown the presence of alpha-1 receptors [4] This is of clinical significance in Horner’s syndrome where the interruption of sympathetic supply to the muscle can result in ptosis and an elevation of ... contributions SW and PS clinically diagnosed and managed our patient including the surgical intervention needed Both authors were involved in writing the manuscript and approved the final version for ... knowledge and given the recent use of tamsulosinin our patient, we hypothesize that there was an alpha-1 blockade on the Muller’s muscle in the right lower lid This led to increased lower lid...
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báo cáo khoa học: " Assessing the spatial distribution of methadone clinic clients and their access to treatment" ppsx
Ngày tải lên :
11/08/2014, 18:20
... and the utilization of clinic services on the other, as exemplified by the situation in Hong Kong In interpreting the results in the study, there are two unique features of heroin dependence in ... Page of Figure Map of Hong Kong showing boundaries of 18 administrative districts, location of 20 methadone clinics including the study clinic and the district where the clinic is located ering in ... location of respondents living in the district was very close to that of the residential buildings The methadone clinic was within the buffer zone representing 67% (1 Standard Deviation/S.D.) of the...
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