beta fibroblast growth factors and other candidate genes

... MLV-encoding nucleic acids: implications for XMRV and other candidate human retroviruses Retrovirology 2010 7:112 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient ... trace amounts of mouse genomic DNA in human blood and tissue samples, and (iii) DNA or RNA from human tumor cell lines infected with XMRV or other closely-related gammaretroviruses PCR testing ... PCR testing for IAP sequences [8,9] should prove useful in further studies of XMRV, as well as other candidate human retroviruses, in which the confounding effects of mouse DNA contamination must...

Ngày tải lên: 13/08/2014, 01:20

... and/ or growth factors (10 ng/ml), and supernatants analyzed by ELISA Mean & SEM, n = RA FLS lines Asterisk indicates P < 0.05 between the combination and the added values for TNF alone and growth ... Since the mRNA and protein results essentially mirrored each other (compare for example Figures and 4, and Figures 5a and 5b), the underlying reason for the synergy of the two growth factors along ... IL8, MIP1α and MMP3), while leaving some other mediators unaltered Both PDGF and TGF-β induce proliferation of FLS [3,5,7], and cytokine-induced growth of FLS is potentiated by PDGF [17] and TGF-β...

Ngày tải lên: 12/08/2014, 12:20

... references and index ISBN 1-58829-302-5 (alk paper) Hematopoietic growth factors Therapeutic use Hematopoietic growth factors Mechanism of action Cancer-Chemotherapy [DNLM: Hematopoietic Cell Growth Factors ... proliferation and development of these cells was dependent on growth factors In cultures, these growth factors were provided by serum, conditioned medium, or cell underlayers The growth factors present ... Transcription Factors and Other Nuclear Proteins, edited by Nicholas B La Thangue and Lan R Bandara, 2002 Tumor Targeting in Cancer Therapy, edited by Michel Pagé, 2002 Hormone Therapy in Breast and Prostate...

Ngày tải lên: 16/02/2014, 07:20

... PDGF-C and -D, structure and function L J Reigstad et al endothelial growth factors (VEGF) and the family is therefore often referred to as the PDGF ⁄ VEGF family The PDGF family of growth factors ... the C-terminal growth factor domain (Fig 1A) The pdgf genes are located on four different chromosomes; PDGF-a and -b on chromosomes and 22 [17,18], and PDGF-c and -d on chromosomes and 11 [19], ... the four pdgf genes contains a long 5¢ untranslated region and a verified (PDGF-a and -b) or putative (PDGF-c and -d) signal peptide in exon (Fig 1B) In the PDGF-c and -d genes, exons and encode...

Ngày tải lên: 19/02/2014, 07:20

... and lM) with TGFb1; (D) WFIKKN2 (250 AND 500 nM, and 1, and lM) with TGFb1; (E) WFIKKN1 (400 and 750 nM, and lM) with BMP2; (F) WFIKKN2 (50, 100, 250 and 500 nM) with BMP2; (G) WFIKKN1 (500 and ... homodimer growth factor remain associated after proteolytic cleavage [2–4] The prodomain ⁄ growth factor complexes confer latency on the growth factors and the active homodimeric growth factors ... 750 nM, and 1.5 lM) with BMP3; (H) WFIKKN2 (100, 250 and 500 nM, and lM) with BMP3; (I) WFIKKN1 (250, 500 and 750 nM, 1, 1.25, 1.5 and lM) with BMP8b; (J) WFIKKN2 (250, 500 and 750 nM, and 1.5...

Ngày tải lên: 06/03/2014, 02:20

... TARs in England & Wales, Scotland, Northern Ireland, Republic of Ireland, Sweden, Czech Republic, Finland, and Denmark; 1968-2006 Table Model Fitting by Country: Regression Intercept and Coefficients, ... incidence is available (2005 for Republic of Ireland; 2004 for England & Wales, Scotland, Northern Ireland, and Sweden; 2003 for Czech Republic and Finland; 2001 for Denmark) Linear Regression Response ... within Ages 45-49 in England & Wales, Scotland, Northern Ireland, Republic of Ireland, Sweden, Czech Republic, Finland, and Denmark; 1943-2005 Cancer registrations in Scotland started in 1960 Rates...

Ngày tải lên: 06/03/2014, 02:21

... requirements on credit growth see Drehmann, and others (2010) and Peydró-Alcalde and other (2011) For a study on dynamic provisions see Chan-Lau (2011) See Gray (2011) for a complementary and recent discussion ... alternative approaches for managing capital flows in Agénor and others (2012), IMF (2011), and Ostry and others (2011) 10 Agénor and others (2012) show in a small open economy DSGE model how a ... indicate that RRs and other macroprudential policies lead to a moderate and transitory slowdown in the growth of bank credit to the private sector (Figure 9) Figure 9: Impact of RRs and other Macroprudential...

Ngày tải lên: 06/03/2014, 04:21

... Contributing Factors, Specific Cases of Autoimmune Diseases, and Stem Cell and Other Therapies” aims to present the latest knowledge and insights regarding the different contributing factors and their ... Sclerosis Pathogenesis and Treatment Marcus Muller, Rachael Terry, Stephen D Miller and Daniel R Getts Chapter Immunologic and Genetic Factors in Type Diabetes Mellitus 25 Ahmad Massoud and Amir Hossein ... Pathogenesis and Treatment and consistent association between the HLA-DRB5*0101, HLA-DRB1*1501, HLA-DQA1*0102 and HLA-DQB1*0602 extended haplotype and disease (Fogdell et al., 1995) As these genes...

Ngày tải lên: 16/03/2014, 21:20

... Transduction of Candidate Growth Factor Peptide Ligand Signals 792 Examples of Peptide Growth Factor Signaling Pathways 792 Growth Factors and Lung Development 792 Candidate Growth Factors in Lung ... Morphogenesis: Vasculogenesis, Angiogenesis and Arteriogenesis 909 Endothelial Cell Differentiation and Hematopoiesis 910 Adult Arteriogenesis and Vasculogenesis 911 Endothelial Cell Growth and ... Compartmentalization of Gastric Glands 761 Hormones and Growth Factors 762 ECM and Integrins 763 Intestinal Cell Proliferation and Differentiation 765 Hormones and Growth Factors 765 ECM and Integrins 766 XIX...

Ngày tải lên: 03/04/2014, 12:05

... These images were from hippocampal CA1 and two cortical regions, one at the midline and another at the superior aspects of the temporal cortex and were acquired and analyzed using NIS-Elements BR3 ... Apolipoprotein E and beta- amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent Brain Res 1999, 843:87-94 Bertrand ... activation of extrasynaptic NMDA receptors, p38-MAPK, and the inhibition of ERK signaling; synaptic receptors, on the other hand, appear to activate ERK and promote survival [70-72] In conclusion, the...

Ngày tải lên: 19/06/2014, 22:20

... City, and in rural communities Indoor SO2 was measured in a random sample of selected households and using logistic regression and controlling for important covariates (excluding PM10 and SO2) and ... the terms "cough" and "sulphur" (Fig 3) Some of them, but others not, found associations between SO2 exposure and respiratory symptoms such as chronic cough and daily mortality and morbidity In ... Occupational Medicine and Toxicology 2006, 1:6 Figure and as assessed by a PubMed search and environmental factors "environmental" related to coughfor the dates Frequency of studies and different publicationterms...

Ngày tải lên: 20/06/2014, 00:20

... matrix apposition in vitro by local growth factors: a comparison between Insulin-like growth factor I, platelet-derived growth factor and transforming growth factor beta Endocrinology 1990, 127:69-75 ... different growth factors stained with a combination of AP (blue) and v Kossa Figure a-d) hOB 15 days after culturing with different growth factors stained with a combination of AP (blue) and v Kossa ... effect on collagen-1 and osteocalcin synthesis was observed after treatment with growth factors (data not shown) C2C12 cell line All three growth factors, PDGFbb, IGF-I and BMP-2, stimulated...

Ngày tải lên: 20/06/2014, 01:20

... different from those caused by P gonapodyides and P. cambivora isolates on one hand and from the most aggressive P cinnamomi isolate on the other hand (Table 1) Infection experiment II Confirmation ... cultivars and MM106 roostock Journal of Agronomy, 5: 321–325 Brasier C.M., Kirk S.A (2001): Comparative aggressiveness of standard and variant hybrid alder phytophthoras, Phytophthora cambivora and other ... experiments and the same inoculation and cultivation technique allowed us to compare the infection development between two periods during the growing season: June (the first and second experiments) and...

Ngày tải lên: 07/08/2014, 10:21

... of the type 1–4 on growths of other classes of structures besides permutations and ordered graphs We shall generalize only and 3, i.e., the constant dichotomy (Theorem 3.1) and the Fibonacci dichotomy ... sends fi to ei and is increasing The image of each such mapping m is e∈B e and m is unique If H is another graph with the stated property and m is the corresponding mapping, m ◦ (m )−1 and m ◦ m−1 ... is defined whenever f ∈ Em(K, L) and g ∈ Em(L, M ) for K, L, M ∈ O and the result is an embedding of K in M This operation is associative and has unique left and right neutral elements id K ∈...

Ngày tải lên: 07/08/2014, 21:20

... assess the species composition and biology of the entomofauna feeding on seed cones of P cembra, and then to measure the respective impact of insects and other mortality factors on the potential of ... selected per tree and tagged The position of the conelets and cones was mapped, and the branches were then surveyed according to the methods developed by Ebel and Yates (1974) and Rauf et al (1985) ... tree species and per surface unit be- development and action of mortality factors, especially insect attack, tween seed cone have been observed in Pinus spp other than pines (Ebel and Yates, 1974;...

Ngày tải lên: 08/08/2014, 18:21

... between severely damaged logs and defect-free logs The biological control of these factors, ie growth stresses and cell-wall properties, may be quite different Growth stress mainly depends on ... fibres) by standard colorific methods, has only been made for trees in this study Crack growth strength tests Crack growth ing a strength can be estimated by loadprecracked specimen and measuring ... be separated, with an average value and a standard deviation for each population One of these is composed of normal wood and is homogeneous in Sg, δ and py The second population corresponds...

Ngày tải lên: 08/08/2014, 19:21

... non-FGF2-expanded (black bars) and FGF2aggregates expanded (grey bars) meniscus cells under normoxia (-) or hypoxia (+), and GAG content of cell aggregate normalised to DNA content FGF2, fibroblast growth ... during 2D expansion and BMP2 during 3D cultivation Specific growth factors during the expansion and redifferentiation of adult human articular chondrocytes enhance chondrogenesis and cartilaginous ... from fibroblast growth factor (FGF2)-expanded versus non-FGF2-expanded cells P2, passage 2; P3, passage AGCTTCTGTGGAACCATGGAA-3' (reverse); COL2A1, 5'CTGCAAAATAAAATCTCGGTGTTCT-3' (forward) and...

Ngày tải lên: 09/08/2014, 07:20

... 1, and potential candidate genes within the confidence intervals of loci 1, 2, 3, 5, and 8, respectively, while no candidate gene was identified for loci and Table summarises the 21 candidate genes ... relatively high P values and overlap with previously-identified arthritis QTL The second approach is investigating candidate genes using both mouse and human studies Candidate genes will be selected ... susceptibility genes inside these two QTL might not affect the phenotype by regulating gene expression Two of the 21 candidate genes were reported to be involved in arthritis Mapk14, a candidate gene...

Ngày tải lên: 09/08/2014, 10:20

... 5) The other prognostic factors showed no significant influence on colostomy free survival Other risk factors The remaining risk factors like N stage, tumor localisation, radiation dose and therapy ... dose of radiotherapy In this case radiochemotherapy was stopped after first cycle of chemotherapy at a dose of 43 Gy because of toxicity and old age of the patient The intensity of chemotherapy ... combined radiochemotherapy have been published to our knowledge The aim of this retrospective analysis was to evaluate the correlation between smoking behaviour and other risk factors and the outcome...

Ngày tải lên: 09/08/2014, 10:21

... (b), and cells SOX genes (c) in monolayer with and without FGF-2-supplemented medium to determine basal levels and following subsequent chondrogenesis for 14 days is shown Data are mean ± standard ... for collagen type I and II, aggrecan, and control IgG in cell aggregates following chondrogenic differentiation for 14 days in IPFP cells expanded with and without fibroblast growth factor-2 (FGF-2)-supplemented ... staining on passage IPFP cells expanded in the absence (a) and cells presence (b) of fibroblast growth factor-2 (FGF-2) was performed using a panel of antibodies and fluorescein isothiocyanate-conjugated...

Ngày tải lên: 09/08/2014, 10:23