bereavement and sudden unexpected death in epilepsy

... benefit and/ or risk in sudden unexpected death in epilepsy? J Clin Pharmacol 2002, 42(2):123-136 15 Asadi-Pooya AA, Sperling MR: Clinical features of sudden unexpected death in epilepsy J Clin Neurophysiol ... L, Ryvlin P: Sudden unexpected death in epilepsy (SUDEP): update and reflections Neurol Clin 2009, 27(4):1063-1074 11 Friedman R: Cardiac role in sudden unexplained death in idiopathic epilepsy ... The published National Institute for Clinical Excellence guidelines state that “individuals with epilepsy and their families and/ or carers should be given and have access to information on SUDEP”...

Ngày tải lên: 10/08/2014, 23:20

... interpreting signs and symptoms for the individuals at risk [11,12] In addition, information of being at risk of a possible life-threatening cardiac disorder and experiencing sudden cardiac death ... cardiomyopathy-related deaths: theory and practice Heart 2008, 94:1269-1275 Vincent GM: The Long QT and Brugada syndromes: causes of unexpected syncope and sudden cardiac death in children and young adults Semin ... participated in preparation and the editing of the article All authors have read and approved the final manuscript Competing interests The authors declare that they have no competing interests Hamang...

Ngày tải lên: 20/06/2014, 15:20

... and were also negative to propidium iodide staining (data not shown), indicating that the plasma membrane is maintained intact, allowing us to exclude primary necrosis as the principal cell death ... depletion induced no major changes in cell cycle and in mitochondria aspect and network, and suggest that ADF cells possess alternative mechanisms for providing mitochondria with ATP and maintaining ... ANT1-silencing induces glioblastoma cell death A Lena et al both morphological examination and propidium iodide staining, thus allowing us to exclude primary necrosis as a principal death modality...

Ngày tải lên: 29/03/2014, 09:20

... and SD were major contributors in writing the manuscript VP and FA performed and interpreted the genetic analysis MF and PB performed clinical evaluations All authors read and approved the final ... presenting with sudden unexplained death in the operating room: a case report Journal of Medical Case Reports 2011 5:222 surgery may have clinical implications: diagnosing OTCS in trigonocephalic ... anomalies that could have explained death during surgery However, as in Opitz’s patient the cause of death was an unexpected massive bleeding Conclusion OTCS is a complex and heterogeneous condition...

Ngày tải lên: 10/08/2014, 23:21

... growing importance in the stillborn syndrome Sluijter et al (1990) and Simpson (1990) also reported increasing incidences of stillbirths in heifer calvings in the Netherlands and in England, ... Stillbirth and death in calves 115 Table Post mortem weights of calves (kg) in different cause -and- time of death categories Cause -and- time of death N Mean SD Min Max Difficult calving Intrauterine death ... preparing for calving and the calving process of about 4000 first calving Swedish Holstein cows was followed by detailed observations recorded in calving reports (Berglund 1996) These contained information...

Ngày tải lên: 12/08/2014, 15:20

... explicitly defined as death that occurred “suddenly and unexpectedly” in a patient in otherwise stable condition and included witnessed deaths (with or without documentation of arrhythmia) and unwitnessed ... England Journal of Medicine CORRECTION Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both Sudden Death in Patients with Myocardial Infarction ... LXRα is expressed predominantly in tissues involved in lipid homeostasis in the liver, intestine, adipose tissue, and macrophages LXRα and LXRβ are equally effective in promoting reverse cholesterol...

Ngày tải lên: 27/06/2014, 00:20

... 2:the different ways to express the death in english and in vietnamese I.words expressing the death in english and in vietnamese: Words expressing the death in English belong to different part of ... put to death at death dawn Chapter III: Some suggestions for translating and learning the ways to expresss the death In translating: Translation, by definition, is rendering a written text into ... life or death for the people in the war zone To be sick to death Chán đến chết Youve been giving me the same of something/doing something old excuses for months and Im sick to death of hearing them...

Ngày tải lên: 27/12/2013, 14:16

... imatinib therapy have point mutations in the BCR–ABL kinase domain, including the T315I gatekeeper mutation that impairs imatinib binding [58,59] Accordingly, new therapies are being tested and ... mutations in the EGFR tyrosine kinase domain; these primary mutations correlate well with clinical responses to the EGFR-specific, ATP-competitive tyrosine kinase inhibitors gefitinib and erlotinib, indicating ... include second-generation tyrosine kinase inhibitors, such as dasatinib (inhibits BCR–ABL, KIT, PDGFR and SRC family kinases), nilotinib (a more potent inhibitor of BCR–ABL, KIT and PDGFR), INNO406...

Ngày tải lên: 16/03/2014, 00:20

... with an increased risk of sudden death Using these parameters, there is a wide variation in the risk of sudden death Forty-two percent of sudden deaths in males and 53% in females occur in onetenth ... record giving an indication whether death was both sudden and unexpected. 6 Death during hospitalisation is in most cases non -sudden and even when a terminal arrhythmia is documented it is, in many ... discharged When deaths are classified in such studies, mortality should be divided into death during index-hospitalisation and death following discharge Patients dying in coma following a cardiac...

Ngày tải lên: 22/03/2014, 18:20

... HERs are commonly activated upon binding of a ligand in their extracellular domain, resulting in dimerization of HERs and triggering the intrinsic tyrosine kinase activity of the receptors responsible ... better understanding of carcinogenesis in diverse tissues, e.g the mammary gland (Johnstone et al, 2002) Both extrinsic and intrinsic stimuli can initiate apoptotic signaling, which involves the ... organs, including mammary glands, in female goats and sheep (Glascock and Hoekstra 1959) This finding was a crucial observation to understand the role of estrogens in processes involving target...

Ngày tải lên: 23/03/2014, 17:20

... tropomyosin and the actin-bundling protein, a-actinin Finally, myosin is recruited and is concentrated in a few distinct dots along the cortex [4] When examined by scanning electron microscopy in detergent-extracted ... can induce apoptosis by suppressing integrin-mediated cell adhesion and survival signalling [53], and can inhibit the association of talin head domain with integrin to suppress the integrin–Cdc42 ... proteins, actin, actin-bundling proteins and contractile proteins Indeed, as bleb expansion slows, the ERM protein ezrin (and possibly moesin) is rapidly recruited to the bleb membrane [4] to link...

Ngày tải lên: 29/03/2014, 08:20

... tumours and are now being tested in combination therapies [47] Tyrosine kinase inhibitors are widely and successfully used in the treatment of cancer, and in the context of this review, may inhibit ... activating DAPK activity [40] Indeed, bosutinib, an investigational Src kinase inhibitor, has been shown to inhibit the migration and invasion of breast cancer cells [48] In addition, dasatinib, ... (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells Clin Cancer Res...

Ngày tải lên: 29/03/2014, 08:20

... live in Asia, mainly in South Central Asia, and one quarter of them live in Africa Better understanding of this problem and meaningful investment in policies to improve the physical growth and ... are coordinated with spinal cord and peripheral receptors to provide integrated thermoregulatory responses, including changes in behavior In the hypothalamus neuroendocrine cells secrete minuscule ... called cytokines, which regulate many physiological processes and are involved in structural remodeling of organ systems These cytokines are produced in and released from various cells and bind to...

Ngày tải lên: 11/06/2014, 10:45

... Annexin V/PI staining and immunofluorescent staining with Hoechst 33342 Annexin V/PI staining showed that percentage of apoptosis were 3.66%, 5.52%, 15.83%, 24.43% respectively for 24 hr, and ... NB4-R2 cells In addition, we also found that Akt signaling inhibitor API-2 could inhibit Akt-1 phosphorylation and induced apoptosis (data not show), indicating NB4-R2 cell apoptotic death induced ... usage of VX-680 inhibition of Aurora kinase in ATRA-resistant APL remains unknown Here we showed that Aurora kinase small-molecule inhibitor VX-680 led to mitotic defects in spindle and decreased...

Ngày tải lên: 18/06/2014, 19:20

... matrix shown in C is indicated in D Similar analysis as in A and B was used, but included only MPTP-treated values and assigned value of for no treatment and 10, 30 and 50 for increasing dosage ... to dopaminergic neuronal death by oxidizing dopamine to a reactive dopamine quinone [51], by increasing DNA oxidation [7], or through increased microglial activation leading to chronic inflammation ... of oxidative and inflammatory insults The positive feed back loop may continue until the additional neuronal death (~50% of the remaining of the initial death) combined with the initial loss...

Ngày tải lên: 19/06/2014, 22:20

... Annexin V/PI staining and immunofluorescent staining with Hoechst 33342 Annexin V/PI staining showed that percentage of apoptosis were 3.66%, 5.52%, 15.83%, 24.43% respectively for 24 hr, and ... NB4-R2 cells In addition, we also found that Akt signaling inhibitor API-2 could inhibit Akt-1 phosphorylation and induced apoptosis (data not show), indicating NB4-R2 cell apoptotic death induced ... usage of VX-680 inhibition of Aurora kinase in ATRA-resistant APL remains unknown Here we showed that Aurora kinase small-molecule inhibitor VX-680 led to mitotic defects in spindle and decreased...

Ngày tải lên: 20/06/2014, 03:20

... HERs are commonly activated upon binding of a ligand in their extracellular domain, resulting in dimerization of HERs and triggering the intrinsic tyrosine kinase activity of the receptors responsible ... better understanding of carcinogenesis in diverse tissues, e.g the mammary gland (Johnstone et al, 2002) Both extrinsic and intrinsic stimuli can initiate apoptotic signaling, which involves the ... organs, including mammary glands, in female goats and sheep (Glascock and Hoekstra 1959) This finding was a crucial observation to understand the role of estrogens in processes involving target...

Ngày tải lên: 27/06/2014, 11:20

... Sered, Susan Starr Uninsured in America : life and death in the land of opportunity / Susan Starr Sered and Rushika Fernandopulle p ; cm Includes bibliographical references and index ISBN 0-520-24442-7 ... Loretta and Greg’s Story \ xv Introduction: The Death Spiral \ 1 From Working Class to Working Poor: The Death of Industry in America’s Heartland \ 21 Medicaid, Welfare Reform, and Low-Wage Work in ... UNINSURED IN AMERICA UNINSURED IN AMERICA LIFE AND DEATH IN THE LAND OF OPPORTUNITY SUSAN STARR SERED AND RUSHIKA FERNANDOPULLE UNIVERSITY OF CALIFORNIA PRESS...

Ngày tải lên: 06/07/2014, 15:37

... score and the type of epilepsy syndrome SFE: symptomatic focal epilepsy, CFE: cryptogenic focal epilepsy, IGE: idiopathic generalized epilepsy A linear regression line and the 95% confidence band ... common in patients with newly diagnosed and chronic epilepsy and provide further insight to the association of depression and anxiety with certain demographic and seizure-related variables Competing ... patients with epilepsy and depression [8] Our results are in line with this latter study, showing a trend towards significant association between female gender and depression in epilepsy The lack...

Ngày tải lên: 08/08/2014, 23:20