... consumption categories used in Tables to aAt age 20 to 35 years Page of (page number not for citation purposes) Arthritis Research & Therapy Table Vol No Benito-Garcia et al Rate ratios ofrheumatoidarthritis ... median intake of each nutrient in each quintile as a continuous variable eAnimal and vegetable protein were adjusted for each other, total iron, and for the same variables adjusted for in all ... multivariate models fTotal iron was adjusted for total protein as well as for the same variables adjusted for in all the multivariate models gDietary and supplemental iron were adjusted for each...
... conducted a caspase activity assay MK-4 activated caspase assay in a dose-dependent manner (Fig 2C) By contrast, vitamin K1 did not show any effects on caspase activity and DNA fragmentation (data not ... six patients with RA and synoviocytes were maintained in separate cultures These patients had active RA as defined by the clinical criteria of the American Rheumatism Association [25] All RA patients ... apoptosis in leukemia cells and enhance the effect of all-trans retinoic acid Leukemia 11, 779–787 10 Yaguchi M, Miyazawa M, Otawa M, Katagiri T, Nishimaki J, Uchida Y, Iwase O, Gotoh A, Kawanishi...
... Rheumatism/World Health Organization–International League of Associations for Rheumatology) core set variables of disease activity [13-15] are available, such as the Disease Activity Score (DAS) ... source of data employed was a large observational cohort of RA outpatients, who were seen on a regular basis, usually every months At each visit clinical, functional and laboratory core set variables ... Haagsma CJ, Rich B, Wells G, Lange ML, Felson DT: ACR and EULAR improvement criteria have comparable validity in rheumatoidarthritis trials American College of Rheumatology European League of...
... methotrexate and sulfasalazine (adalimumab, abatacept and rituximab were not yet available for RA) For the second method, prescriptions for each DMARD were counted once and added to obtain the total ... using data from the medical chart review Using Spearman non-parametric tests, the correlations between the RARBIS and various forms of administrative data variables were then analysed Data taken ... orders for inflammatory markers, rehabilitation visits, Table Claims-based index ofrheumatoidarthritis severity (CIRAS) score (mean, range) and Spearman correlation of CIRAS score with rheumatoid...
... the quadriceps tendon, medial border of the patella, and the medial border of the patellar tendon A medial, parapatellar, capsular incision was made, and the patella was dislocated laterally to ... In addition, the surgical results have not been satisfactory for advanced disease which creates bony destruction [4] Total joint replacement arthroplasty is the standard treatment for severe arthritis ... effective for treating rheumatoidarthritisof the knee Special thanks to Bonnie Hami, MA (USA) for editing this manuscript References 10 11 American College of Rheumatology Subcommittee on Rheumatoid...
... Shortened Arthritis Impact Measurement Scales, AIMS2 = Arthritis Impact Measurement Scales 2, CSHQ-RA = Cedars-Sinai Health Related Quality of Life forRheumatoidArthritis instrument, CSHQ-RA Revised ... functional capacity, since it cannot measure improvement in a substantial proportion of patients Both the MDHAQ (14 ADL) and the HAQ-II were rated favorably for all aspects of validity as well and ... this article as: Oude Voshaar et al.: Measurement properties of physical function scales validated for use in patients with rheumatoid arthritis: A systematic reviewof the literature Health and...
... College of Rheumatology; DAS28, Disease Activity Score 28 joint count; EULAR, European League Against Rheumatism ABA, abatacept, ADA, adamlimumab, ANA, anakinra, ETN, etanercept, GLM, golimumab, ... rheumatoid arthritis; ACR, American College of Rheumatology; DAS28, Disease Activity Score 28 joint count; EULAR, European League Against Rheumatism; ABA, abatacept, ADA, adalimumab, ETN, etanercept, ... http:/ /arthritis- research.com/content/13/1/R25 Page of 15 Table Biologic DMARDs for the treatment of RAa Generic drug name (brand Structure and mechanism of action name, year of FDA approval) Mode and frequency of administration TNF -a inhibitors...
... curve (AUC) were calculated using GraphPad Prism software (GraphPad, La Jolla, CA, USA) Statistical analysis regarding autoantibody test results and disease variables obtained from medical records ... anti-dsDNA antibodies are always associated with antinucleosome antibodies (ANuA), but not vice versa, and that ANuA are exhibited prior to anti-dsDNA antibodies So, it also became clear that the mass ... performance criteria of the AntidsDNA-NcX ELISA with those of other assays for measuring antibodies against dsDNA and/or nucleosomes, Page of the new ELISA was compared with the anti-dsDNA ELISA,...
... disease activity indices forrheumatoid arthritis: validation ofa clinical activity score Arthritis Res Ther 2005, 7:R796-806 van Gestel AM, Haagsma CJ, van Riel PL: Validation ofrheumatoidarthritis ... Singh JA, Holmgren AR, Noorbaloochi S: Accuracy of Veterans Administration databases fora diagnosis ofrheumatoidarthritisArthritis Rheum 2004, 51:952-957 Losina E, Barrett J, Baron JA, Katz ... evaluation ofa large number of patients participating in an RA registry at 11 VHA medical centers All patients had rheumatologist-confirmed RA and wellcharacterized measures of RA disease activity...
... functioning For example, the provision of medication to control the progression of RA and manage pain a) Onset and management of RA The nature and disease duration varied greatly between participants ... and services, time use on a typical day, costs associated with having arthritis and income sources available, social relations and social involvement and feelings about quality of life and satisfaction ... South Africa The data were transcribed and translated by the research assistant who did the interviews The transcripts were analyzed using a basic thematic analysis approach with the main topics...
... affinity of shared epitope alleles to candidate au toantigens and, thus, may be an important trigger in the early inflammation that characterzes RA Although lacking periodonal examinations, a ... Univariate relationships with an RA diagnosis (RA versus OA) were examined using the chisquare x2 test for categoric variables and one-way analysis of variance for continuous variables To investigate multivariate ... RA patients had an age range of 33 to 86 years (mean age =62 years), while the OA patients’ age range was 24 to 82 years (mean age =58 years) Twenty-eight edantulous patients, 22(245) with RA...
... Kitas G: Dyslipidemia and rheumatoidarthritis Ann Rheum Dis 1997, 56:341-342 41 Georgiadis AN, Papavasiliou EC, Lourida ES, Alamanos Y, Kostara C, Tselepis AD, Drosos AA: Atherogenic lipid profile ... ischaemic heart disease in rheumatoidarthritis Rheumatology (Oxford) 2003, 42:607-613 Van Doornum S, McColl G, Wicks IP: Accelerated atherosclerosis: an extraarticular feature ofrheumatoid arthritis? ... (percentage), as appropriate Comparisons were performed by analysis of variance, KruskalWallis, and chi-square test for normally distributed, non-normally distributed, and categorical variables,...
... Hyperfilm (Amersham Pharmacia Biotech UK) Statistical analysis Comparison of data was assessed using GraphPad Prism version 3.0 (GraphPad Software Inc, San Diego, CA, USA) Statistical differences ... Arthritis Research & Therapy Vol No Foey et al demonstrated the potential for the cAMP/protein kinase A (PKA) pathway in treatment of autoimmune diseases such as RA Another stimulator of the ... examine the potential of VIP as a therapeutic agent in chronic inflammatory diseases such as RA by investigating its effects on human macrophages, T cells, and synovial cells — all of which play...
... values are for one-tailed t-tests and Fisher’s exact test, as appropriate DMARD, disease-modifying antirheumatic drug; HAQ, Health Assessment Questionnaire; NSAID, nonsteroidal anti-inflammatory ... Treatments Patients were randomized to receive IFN-β- 1a (30 µg intramuscular weekly) or matched placebo in a 3:1 ratio at each of two sites (Stanford University and the University of Alabama at ... placebo and interferon groups were analyzed using Fisher’s exact test The primary analysis of efficacy end points was based on an intention-to-treat (ITT) approach All patients were analyzed according...
... TGF-beta Nat Med 1996, 2:1132-1136 Kameda T, Mano H, Yuasa T, Mori Y, Miyazawa K, Shiokawa M, Nakamaru Y, Hiroi E, Hiura K, Kameda A, et al.: Estrogen inhibits Available online http:/ /arthritis- research.com/content/6/5/R457 ... patient's assessment of general health using a Visual Analogue Scale of 100 mm Statistical analysis The primary end points of the original study were radiographic progression of joint damage and ... 46 Hasegawa J, Nagashima M, Yamamoto M, Nishijima T, Katsumata S, Yoshino S: Bone resorption and inflammatory inhibition efficacy of intermittent cyclical etidronate therapy in rheumatoid arthritis...
... preparation EHG carried out statistical analysis and manuscript preparation TBG carried out patient referral, clinical data analysis and manuscript preparation MHP carried out patient referral, ... role of NK cells in autoimmune disease Autoimmunity 2002, 35:1-14 29 Yabuhara A, Yang FC, Nakazawa T, Iwasaki Y, Mori T, Koike K, Kawa H, Komiyama A: A killing defect of natural killer cells as an ... Arthritis Research & Therapy Vol No Villanueva et al Table Clinical characteristics of patients with juvenile rheumatoidarthritis Parameter Male/female Systemic onset JRA (n = 20) Polyarticular...
... Ikari K, Kuwahara M, Nakamura T, Momohara S, Hara M, Yamanaka H, Tomatsu T, Kamatani N: Association between PADI4 and Page of (page number not for citation purposes) 16 17 18 19 20 rheumatoid arthritis: ... rheumatoidarthritisArthritis Rheum 2005, 52:3058-3062 Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, et al.: Functional haplotypes of PADI4, ... 64:1316-1320 Martinez A, Valdivia A, Pascual-Salcedo D, Lamas JR, FernandezArquero M, Balsa A, Fernandez-Gutierrez B, de la Concha EG, Urcelay E: PADI4 polymorphisms are not associated with rheumatoid arthritis...
... preparation of the manuscript, and was responsible for the analysis of the rheumatoid factors BC was a main clinical investigator, contributed to the preparation of the manuscript, and was involved ... Sedova L, Kafkova J, Gatterova J, Pesakova V, Ruzickova S: Autoantibodies can be prognostic markers of an erosive disease in early rheumatoidarthritis Ann Rheum Dis 2003, 62:427-430 Saraux A, ... DMFM, van Riel OLCM, van Leuween MA, van't Hof MA, van Rijswijk MH, van de Putte LBA: Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis: a prospective...
... of data, analysis of data and interpretation of data and writing the manuscript AaV: acquisition and analysis of data SJ: interpretation of data and drafting the manuscript HST: acquisition and ... and analysis of data MØ: study design, analysis of data and interpretation of data and writing the manuscript Acknowledgements Amersham Health The Danish Rheumatism Association References Arnett ... of cm Merge eFilm™(Milwaukee, Wisconsin, USA) workstation, a commercially available software package, was used for the readings of the MRI images This software enables digital image viewing and...
... Survival in rheumatoid arthritis: a population-based analysis of trends over 40 years Arthritis Rheum 2003, 48:54-58 Isomaki HA, Mutru O, Koota K: Death rate and causes of death in patients with rheumatoid ... 290:1797-1799 Watson DJ, Rhodes T, Guess HA: All-cause mortality and vascular events among patients with rheumatoid arthritis, osteoarthritis, or no arthritis in the UK General Practice Research Database ... Preliminary definition of improvement in rheumatoidarthritisArthritis Rheum 1995, 38:727-735 Tsimihodimos V, Karabina SA, Tambaki AP, Bairaktari E, Miltiadous G, Goudevenos JA, Cariolou MA, Chapman...