behcet s disease associated with ssc

... diagnosis in children is difficult, as the disease is uncommon and clinically resembles other diseases, such as multiple sclerosis Another important differential diagnosis is central venous sinus ... Myositis and scleritis associated with Behçet s disease: an atypical presentation Ocul Immunol Inflamm 2004, 12:329-332 Sakellariou G, Berberidis C, Vounotrypidia P: A case of Behçet disease with ... optic disc with blurred margins (red-free fundus photograph) Discussion Childhood-onset Behçet s disease is uncommon, accounting for 3% to 7% of all cases [2] Scleritis may be a harbinger of systemic...

Ngày tải lên: 11/08/2014, 00:22

... Behçet s disease was assessed by the 1994 criteria for disease activity of Behçet s disease, proposed by the Behçet s Disease Research Committee of Japan [25] At time of sampling, disease was active ... multiple sclerosis [32] Increased levels of γ/δ T cells have been demonstrated in Behçet s disease [9,15–17], and a role in the pathogenesis of the disease has been also suggested In the present study ... this time the percentage of expansion was assessed by fluorescence activated cell sorting (FACS) analysis using the anti-TCR Vδ2 mAb The results were expressed as EF (see Materials and methods)...

Ngày tải lên: 09/08/2014, 01:23

... present study we found endogenous HO-1 expression to be decreased in PBMCs from patients with active BD Dysregulation of HO-1 expression is associated with some rheumatic diseases Our previous studies ... Behcet' s diseases Am J Ophthalmol 1953, 36:301-315 Lee S, Bang D, Cho YH, Lee ES, Sohn S: Polymerase chain reaction reveals herpes simplex virus DNA in saliva of patients with Behcet' s disease ... by using Scion image analysis and image processing software (NIH Image Engineering, Bethesda, MD, USA) Statistical analysis Mann-Whitney U-test, Kruskal-Wallis test with post-hoc Scheffe 's test,...

Ngày tải lên: 09/08/2014, 10:22

... chromosomal breakpoints impact the level of LMO2 expression in T-ALL Blood 2007, 110:388-392 Yazici H, Fresko I, Yurdakul S: Behçet s syndrome: disease manifestations, management, and advances in treatment ... interests References Cañete JD, Celis R, Noordenbos T, Moll C, Gómez-Puerta JA, Pizcueta P, Palacin A, Tak PP, Sanmartí R, Baeten D: Distinct synovial immunopathology in Behçet disease and psoriatic ... Missotten T, van Daele PL, Jamnitski A, Baarsma GS, van Hagen PM: Adalimumab: a new modality for Behçet s disease? Ann Rheum Dis 2007, 66:565-566 Page of (page number not for citation purposes)...

Ngày tải lên: 09/08/2014, 14:22

... Behçet s disease is high, such as Turkey and others in the Middle and Far East, evidence suggests that this disease should be included among the diagnostic possibilities in cases of Budd-Chiari syndrome ... of 75 patients diagnosed with Budd-Chiari syndrome was Behçet s disease [14] Thus, although it has a worldwide distribution, BuddChiari syndrome associated with Behçet s disease is more common ... where Behçet s disease is prevalent suggests that this disease should be included among the diagnostic possibilities in cases of Budd-Chiari syndrome because the third most common cause from a total...

Ngày tải lên: 11/08/2014, 00:22

... cultures Statistical analysis Results were expressed as the mean standard deviation Statistical differences were assessed using one-way ANOVA with posthoc test of the means according to Tukeys method ... method In single mean comparisons, Students t-test was used to test the data and considered statistically significant for P values

Ngày tải lên: 11/08/2014, 03:20

... Cardiovascular manifestations of Behcet' s disease Ann Med Interne (Paris) 1999, 150:542-554 Silman A, Gul A: Is there a place for large vessel disease in the diagnostic criteria of Behcet' s disease? ... interests Authors’ contributions Discussion Vascular involvement is a well-known characteristic of BD Large vessel disease or acute cerebrovascular infarction in the setting of aphthosis should suggest ... helped with manuscript revision References Ioakimidis D, Georganas C, Panagoulis C, Gournizakis A, Iliopoulos A, Kremastinos D, Kontomerkos T: A case of AdamantiadisBehcet s syndrome presenting as...

Ngày tải lên: 11/08/2014, 14:20

... bruits were detected With the diagnosis of Takayasu 's arteritis, in association with Crohn 's disease, oral prednisolone (30 mg/day) was started plus continuation of her previous medication, i.e sulfasalazine ... women with early manifestations of TA [2,6] As TA mostly presents in young women [7], it could be suggested that patients with inflammatory bowel diseases would show features of TA in the same ... manifestations It seems that one disease triggers or worsens the other [2] Unfortunately, there have been no prospective studies to prove this phenomenon Most of the reported patients with CD...

Ngày tải lên: 11/08/2014, 23:21

... sclerosis, another Th1-mediated disease, in which NK2 bias is associated with disease remission [13] A major limitation of this study is the small number of patients analyzed, especially those ... patients' disease status changed to remission (P = 0.02) Figure Serial gene expression measurements of natural killer cells in active Behçet 's disease Serial gene expression measurements of interleukin-12 ... not reach a statistical significance (P = 0.05) These results strongly suggest that an NK2 shift was associated with disease remission In addition, the expression level of perforin was reduced...

Ngày tải lên: 12/08/2014, 12:20

... standard Edman chemistry, and MS analysis was undertaken using an LCQDECA LC ⁄ MS system (ThermoFinnigan, San Jose, CA, USA) The MS system consisted of a Surveyor HPLC system with a diphenyl 150 ... Analysis Center, University of Uppsala, Sweden Sequence analysis was performed using an Applied Biosystems Procise 492 cLC sequenator (Applied Biosystems, Framingham, MA, USA) employing standard ... cost-effective than production of synthetic peptides, a bacterial expression system allows isotope labeling, which is essential for high-resolution structural analysis of Ab using NMR spectroscopy...

Ngày tải lên: 18/02/2014, 13:20

... aging suggests that these markers could be considered as markers for senescence rather than for inflammation This suggests the rather controversial idea that the high expression levels of these ... Table Clinical status, demographic information, disease duration, neuropathological staging and APOE genotype of control and AD cases used in this study Case Diagnosis Sex Age (years) GDS Braak Brain ... NPs, neuritic plaques; NFTs, neurofibrillary tangles; CTRL, control case; AD, Alzheimer s disease cases P-value indicates difference between regressions of the AD and control groups * indicates...

Ngày tải lên: 19/06/2014, 22:20

... multidisciplinary studies add strength to the possibility of causal associations for a number of health conditions, including diabetes, stroke, and cardiovascular disease However, there is no consensus ... colleagues assessed the role of oral health in cancer risk Using data from the Health Professionals Follow-Up Study (HPFS), they examined whether there was an association between periodontal disease, ... with 25 to 32 teeth Although periodontal disease was associated with significant increases in total (HR, 1.21) and hematological (HR, 1.35) cancers in men who never smoked, no association was...

Ngày tải lên: 29/07/2014, 02:21

... expression libraries using BD sera was used since this approach has been successfully employed in the characterization of many clinically relevant antigens in systemic rheumatic diseases such as SS-A/Ro ... any other disease (Group II, defined as 'probable BD' in this study) Disease controls included 10 patients with SLE and 10 with SjS, all satisfying corresponding international classification ... a BDR1138 Hirohata S, Kikuchi H: Behcet' s disease Arthritis Res Ther 2003, 5:139-146 Criteria for diagnosis of Behcet' s disease International Study Group for Behcet' s Disease Lancet 1990, 335:1078-1080...

Ngày tải lên: 09/08/2014, 07:20

... with distinct autoimmune diseases characterized by the presence of serum anti-endothelial cell antibodies such as BD, systemic lupus erythematosus (SLE), systemic sclerosis (SSc) , various forms of ... primary vasculitis (9 patients with Wegener 's granulomatosis, with Churg-Strauss syndrome, with Takayasu 's Arteritis, with Horton disease, with microscopic poly-angiitis, with panarteritis nodosa), ... patients and healthy subjects Anti-carsubjects boxy-terminal subunit of Sip1 (anti-Sip1 C-ter) antibodies in patients with Behçet 's disease (BD), systemic lupus erythematosus (SLE), systemic sclerosis...

Ngày tải lên: 09/08/2014, 08:22

... crosssectional study was considerably less than that used among the patients with active BD, both in the cross-sectional and in the prospective parts of our study Nevertheless, the study shows ... levels (which not correlate with the clinical activity [1]), disease status was assessed by clinical means only Endothelial dysfunction was assessed by a widely-used, reproducible and non-invasive ... Figure shows that among patients receiving corticosteroids, those with active disease had higher FMD than did those with inactive disease (5.5 ± 1.0% versus 2.7 ± 0.7%; P = 0.034) Those patients with...

Ngày tải lên: 09/08/2014, 10:21

... 38:426-433 Suzuki N, Nara K, Suzuki T: Skewed Th1 responses caused by excessive expression of Txk, a member of the Tec family of tyrosine kinases, in patients with Behcet s disease Clin Med Res 2006, ... Cañete s group has studied SF extensively in various other arthropathies, such as spondyloarthropathy (SpA) and RA, and comparisons may be made with historical data Comparing SF samples between SpA ... and diseasespecific features of BD is the occurrence of a positive skin pathergy reaction (SPR), which is observed in 30% to 75% of all BD patients [2,4] Neutrophils and subsequently lymphohistiocytic...

Ngày tải lên: 09/08/2014, 14:20

... disease present 2.90 rs9513584 Both eye and vascular disease present 1.13 rs4936742 Vascular disease absent 1.81 rs317711 Vascular disease present G rs2061634 Eye disease absent rs11206377 G 1.84 ... involvement and with vascular involvement, suggesting that the disease- associated polymorphism in UBASH3B might predispose to eye and vascular complications in patients with Behçet 's disease Interestingly, ... are associated with Behçet 's disease in our study (Table 3) A subset analysis was performed to examine the difference in allele frequencies in clinical subsets of Behçet 's disease compared with...

Ngày tải lên: 09/08/2014, 14:20

... males have been shown to have a worse prognosis, and the association of these SNPs with sex should be examined Other GWAS are ongoing or planned in Japanese, European and Turkish patients with ... differences in SNPs studied by candidate analysis, and the association of these newly identified SNPs in BD patients from different geographical areas will be important Similarly, in several studies ... in multicase families with Behcet s disease Rheumatology (Oxford) 2005, 52: 1836-1842 Direskeneli H: Autoimmunity vs autoinflammation in Behcet s disease: we oversimplify a complex disorder? Rheumatology...

Ngày tải lên: 09/08/2014, 14:22

Ngày tải lên: 11/08/2014, 02:22