behavior genetic approaches are integral for understanding the etiology of psychopathology

An unifying framework for understanding the electrooxidation of small organic molecules for fuel cell applications

An unifying framework for understanding the electrooxidation of small organic molecules for fuel cell applications

... ln(aox/ ared) where R is the gas constant 8.314 (J K−1 mol−1), T is the temperature (K), aox and ared are the chemical activity of oxidized and reduced forms of the redox species For the reduction of ... “conflicting theories” in the literature The objective of this thesis is therefore to seek a unifying understanding of the reaction mechanisms for the electrooxidation of small oxygenates (mainly ... are the reaction pathways at low pH, while dashed arrows are the pathways for high pH The deprotonation of the CH3 group of CH3CHO forms the enolate anion, CH2=CHO- with good delocalization of...

Ngày tải lên: 28/09/2015, 13:38

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Integrating population genomics and medical genetics for understanding the genetic aetiology of eye traits

Integrating population genomics and medical genetics for understanding the genetic aetiology of eye traits

... 24 Plots of the top 20 regions of the varRecM scores for the comparison between samples of HapMap CEU and JPT+CHB 164 Figure 25 Plots of the top 20 regions of the varRecM scores for the comparison ... regions of the varRecM scores for the comparison between samples of SGVP CHS and INS 170 Figure 28 Plots of the top 20 regions of the varRecM scores for the comparison between samples of SGVP ... elongation of the eyeball to compensate for the optical effects of the lens 35 Therefore the eye becomes myopic because of the excessive elongated axial length Analogously, a positive lens causes the...

Ngày tải lên: 09/09/2015, 10:07

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Báo cáo khoa học: The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme doc

Báo cáo khoa học: The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme doc

... analysis of the exact binding mode has not been performed, but the mode of binding of the acetyl moiety is clearly different from the mode of binding of the acetyl moiety of Ac-CoA Apparently, the ... site of thiolase (A) The overall shape of the biosynthetic thiolase tetramer The four individual active sites of the tetramer are indicated by the bound CoA molecules The catalytic site of the ... OPP; furthermore, the structural changes of the protein part described for the OPP complex are seen as well in the Ac-OPP complex Due to low occupancy of the compound in the structure, further detailed...

Ngày tải lên: 16/03/2014, 04:20

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UNDERSTANDING FISHERIES MANAGEMENT: A Manual for understanding the Federal Fisheries Management Process, Including Analysis of the 1996 Sustainable Fisheries Act doc

UNDERSTANDING FISHERIES MANAGEMENT: A Manual for understanding the Federal Fisheries Management Process, Including Analysis of the 1996 Sustainable Fisheries Act doc

... regions For example, the Southeast Regional Office of the NMFS covers the South Atlantic Council, the Gulf of Mexico Council and the Caribbean Council Contact information for the NMFS Regional Offices ... covers the area; A representative of the Interstate Marine Fisheries Commission for the area (see page 49 for more information); A representative of the U.S Department of State Lists of members are ... stock, the biomass of mature females in the stock, or the biomass of the eggs they produce These measures are called spawning stock biomass (SSB) and when they are put on per-recruit basis they are...

Ngày tải lên: 31/03/2014, 13:20

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Báo cáo y học: "Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity" pps

Báo cáo y học: "Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity" pps

... spreading to other epitopes in the Sm particle This view of the battle between the virus and the immune system is further amplified by the results of the analysis of MHC II T cell epitopes using the ProPred ... autoimmune disease Some of these predictions are characteristic of a wide range of models of autoimmunity and are, therefore, not terribly informative in deciding for or against the model Still, it ... sequences in the B/B' polypeptide followed by spreading to the rest of the Sm particle To further explore the relevance of disorder to the idea of spreading we carried out a PONDR® analysis of the EBNA1...

Ngày tải lên: 09/08/2014, 07:20

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Báo cáo khoa hoc:" A sampling method for estimating the accuracy of predicted breeding values in genetic evaluation" potx

Báo cáo khoa hoc:" A sampling method for estimating the accuracy of predicted breeding values in genetic evaluation" potx

... included in the model The heritability was equal to 0.28 The limited size of the data set allowed the estimation of the true CD by inversion of the coefcient matrix of the mixed model equations (formula ... populations of animals could be assessed by measuring the PEV [4,16] or CD [17,18] of contrast between their genetic merits In theory, PEV and CD are derived from the elements of the inverse of the coefcient ... that the empirical estimators of CD converged to the true values of CD as the number of replicates increased 3.2 Application of the method The large size of the data set prevented estimating the...

Ngày tải lên: 09/08/2014, 18:21

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Báo cáo sinh học: " A linear programming approach for estimating the structure of a sparse linear genetic network from transcript profiling data" pdf

Báo cáo sinh học: " A linear programming approach for estimating the structure of a sparse linear genetic network from transcript profiling data" pdf

... card(A) the cardinality of a set A For a vector x = [x1, , xN]® in this space, the l2 (Euclidean) norm is the square root of the sum of the squares of its elements, x = ∑ n=1 x n ; the l1 norm is the ... to the number of genes N The minimum LOO Error occurs at A = for ALPHA and A = 0.9 for CDC15; the Sparsity is ~15 for these A values The degree of most of the nodes in the LPSLGNs lies in the ... generated from the profile for a given time point whereas the input is generated from the profile for the previous time point; there is no constraint wnn = in the linear interaction model The ith training...

Ngày tải lên: 12/08/2014, 17:20

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Báo cáo khoa học: "Equipment review: The success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation" potx

Báo cáo khoa học: "Equipment review: The success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation" potx

... hospitals in the USA They compared two groups of patients: those who did and those who did not undergo placement of a PAC during their first 24 hours of ICU care They recognized that the value of their ... outcome, therapy, clinician behaviour The majority of evidence to support the use of Presep ScvO2 catheters comes from the work of Rivers and coworkers [6], but there are also a number of optimization ... Critical Care August 2005 Vol No Gunn and Fink What are the primary indications for its use? The primary indication for the use of Presep is as a part of EGDT in the detection and treatment of patients...

Ngày tải lên: 12/08/2014, 22:22

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Báo cáo y học: "Structural features in the Rous sarcoma virus RNA stability element are necessary for sensing the correct termination codon" potx

Báo cáo y học: "Structural features in the Rous sarcoma virus RNA stability element are necessary for sensing the correct termination codon" potx

... sequence of the termination codon and the first nucleotide following the termination codon Furthermore, the 3′UTRs of the other RSV open reading frames of the parental avian leukosis virus (ALV) ... compared to wild-type RNA are considered stable This analysis indicates that the ends of the functional element are at positions 2577 and 2732 of the viral RNA, a deletion of 75 nts from the ... whether spacing within the RNA was altered, sequence was added to the 5’ or 3’ end or at the deletion site D Diagram depicting the organization of the deletion constructs and the location of the...

Ngày tải lên: 13/08/2014, 01:20

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Báo cáo y học: "Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease" potx

Báo cáo y học: "Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease" potx

... addition, the E region is also important in nuclear localization and dimerization of the receptor Indeed, dimerization is essential for the activity of PPARs, as it is for most of the other members of ... the group of synthetic ligands, fibrates are hypolipidaemic drugs used in the treatment of hyperlipidemia Most of them preferentially activate PPARα Others are industrial compounds [37] The insulin-sensitizing ... [70] These regulatory genes are critical in the progression of the cell cycle, particularly the G1 to S transition For example, PPinduced expression of growth regulatory genes precedes entry of the...

Ngày tải lên: 13/08/2014, 13:20

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Báo cáo sinh học: " A criterion for measuring the degree of connectedness in linear models of genetic evaluation" ppt

Báo cáo sinh học: " A criterion for measuring the degree of connectedness in linear models of genetic evaluation" ppt

... notice that the variance Coo.,5 of the conditional distribution of given $ is also the variance of the marginal distribution of under the reduced model (0, A) This leads to view the ratio of determinants ... using the conditional distribution of the 1!IL estimator of one vector or given the value of the other due to the (6 following equality: Similarly, by substitutingto 0: !) and, finally from the ... consider the The roots k of i [18] = (or D = 0) in the case = case of perfect connection characteristic equation: are the eigenvalues of R C CBB’Coo.0 or CF so that: where kg is the geometric mean of...

Ngày tải lên: 14/08/2014, 20:20

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Tài liệu From Data to Knowledge and Back Again: Understanding the Limitations of KMS pdf

Tài liệu From Data to Knowledge and Back Again: Understanding the Limitations of KMS pdf

... from these two platforms for a variety of applications, three of which are presently described While the technical innerworkings of these CBR platforms are certainly of interest (but outside the ... meet the claims of their creators, as the case-based reasoning applications described provided a poor approximation of the ‘horizons of understanding of domain experts whose knowledge they purportedly ... use of the decision tree in consultation mode at the distributed regional interfaces is therefore excluded, in the [initial version of the application] If, in the longer term, it emerges that there...

Ngày tải lên: 20/12/2013, 19:15

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Tài liệu Temi di discussione: Are there asymmetries in the response of bank interest rates to monetary shocks? pdf

Tài liệu Temi di discussione: Are there asymmetries in the response of bank interest rates to monetary shocks? pdf

... calculated in the last years of the sample period Therefore, the lines above the value of one give the outcome of the rank test evaluated for any partial sample period Due to the presence of dummy ... greater number of degrees of freedom The exclusion of the interbank rate from the model can be adopted because of the high velocity of adjustment of the interbank rate to the policy rate in the 1990s ... For more details see the Annual Report of the Bank of Italy for 1993 Data are available on the Internet site of the Bank of Italy (www.bancaditalia.it) 10 The choice of the rate on domestic...

Ngày tải lên: 17/02/2014, 03:20

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Tài liệu Báo cáo khoa học: "An API for Measuring the Relatedness of Words in Wikipedia" docx

Tài liệu Báo cáo khoa học: "An API for Measuring the Relatedness of Words in Wikipedia" docx

... e.g the MediaWiki software5 , integrated within a Linux, Apache, MySQL and PHP (LAMP) software bundle The architecture of the API consists of the following modules: RDBMS: at the lowest level, the ... articles in the categorization graph Examples of programmatic usage of the API are presented in Figure In addition, the software distribution includes UNIX shell scripts to access the API interactively ... encyclopedia page objects and compute the relatedness scores The information flow of the API is summarized by the sequence diagram in Figure The higher input/output layer the user interacts with is provided...

Ngày tải lên: 20/02/2014, 12:20

4 547 1
Tài liệu There are two benches to the left of the shop ppt

Tài liệu There are two benches to the left of the shop ppt

... từ đó) There are two benches to the left of the shop 2 Các bạn di chuột vào cụm từ để biết chức cụm câu: There are two benches to the left of the shop 3 Tại câu lại dịch vậy? -“There are two ... *There are two benches to the left of the shop Hình thức ngữ pháp : cấu trúc: “there are/ is….to the left of ” – (có bên trái gì) Chúng ta quan sát câu ... chia are, were…”) Ví dụ: There is a boy and two girls in the classroom There are two girls and a boy in the classroom Trong câu “benches”- ghế dài – danh từ số nhiều nên động từ "to be" chia are ...

Ngày tải lên: 26/02/2014, 00:20

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Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Settings, 2005 pot

Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Settings, 2005 pot

... is performed in the setting, review the results of screening of other HCWs in the same area of the health-care setting or same occupational group If serial TB screening is not performed in the ... treatment reduces coughing, the amount of sputum produced, the number of organisms in the sputum, and the viability of the organisms in the sputum However, the duration of therapy required to decrease ... droplet nuclei in the air and the duration of exposure to a person with infectious TB disease The closer the proximity and the longer the duration of exposure, the higher the risk is for being infected...

Ngày tải lên: 06/03/2014, 04:20

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Understanding the Value of the MBA: A Program Type Comparison pdf

Understanding the Value of the MBA: A Program Type Comparison pdf

... 2,207, p < 001): the more quickly the investment is recouped, the higher the rating of the overall value of the MBA The overall value of the MBA is also related to the job satisfaction of alumni In ... investigators of the overall value of the MBA, as well as to those on the frontline of MBA program administration whose goal it is to enhance the value of the MBA for their students Contact Information For ... Understanding the Value of the MBA, Bruce Figure shows the distribution of values for the MBA Degree scale and Figure 3, the distribution of values for the School/Program scale Figure Distribution of MBA...

Ngày tải lên: 08/03/2014, 02:21

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Understanding the Securitization of Subprime Mortgage Credit docx

Understanding the Securitization of Subprime Mortgage Credit docx

... 1.4% of the principal balance of the mortgages There are two B classes of securities not offered in the prospectus The mezzanine class benefits from a total of 3.10% of subordination created by the ... the terms of the insurance contract (i.e coupon, maturity, pool of deals) are fixed The ABX tracks the amount that one party has to pay the other at the onset of the contract in order for both ... reduces the average life of these bonds and the interest costs of the securitization In our example securitization, o/c is specified to be 1.4% of the principal balance of the mortgage loans as of the...

Ngày tải lên: 15/03/2014, 10:20

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Bacteria are often maligned as the causes of human and animal disease (like this one, Leptospira, which causes serious disease in livestock)

Bacteria are often maligned as the causes of human and animal disease (like this one, Leptospira, which causes serious disease in livestock)

... - hearing loss - unilateral orchitis( inflammation of one or both of the testes) ** These conditions are usually relieved with the treatment of 1% atropine and steroids Epidemiology      ... as the Democratic Republic of Congo In these two instances the mortality rate was between 50 –90% Following those epidemics, Ebola hit Africa in many other instances the worst yet being in the ... locality of this virus has become less isolated as the threat of bioterrorism looms large The Ebola virus is now on the “A” list for hopeful vaccination development Experiments have even been formed...

Ngày tải lên: 15/03/2014, 13:09

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Research Opportunities for Managing the Department of Energy''''s Transuranic and Mixed Wastes potx

Research Opportunities for Managing the Department of Energy''''s Transuranic and Mixed Wastes potx

... by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of ... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... JR., Office Assistant v vi Preface The production of nuclear materials for the national defense, beginning in the 1940s and continuing until the end of the Cold War, led to the accumulation of...

Ngày tải lên: 15/03/2014, 15:20

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