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... 73, 611 – 620 12 Schlessinger, J (19 93) How receptor tyrosine kinases activate Ras Trends Biochem Sci 18 , 27 3 27 5 13 Pawson, T & Scott, J.D (19 97) Signalling through scaffold, anchoring, and adaptor ... in human tumors Oncogene 18 , 813 – 822 21 Bos, J.L (19 89) ras oncogenes in human cancer: a review Cancer Res 49, 46 82 4689 22 Kholodenko, B.N (20 00) Negative feedback and ultrasensitivity can bring ... J.M (19 95) Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation J Biol Chem 27 0, 25 320 25 323 42 Huang, C.Y & Ferrell, J.E Jr (19 96)...

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... experiments (sequence 11 4 22 5) Two peptides belonging both to the 11 4 22 5 sequence and exposed regions of subdomain were tested (1 12 – 12 5 and 11 9 – 1 32 peptides) Interaction of the 15 9 19 3 fragment with ... fragment was labelled with FITC and mixed with 1 12 12 5 and 11 9– 1 32 actin peptides As shown in Fig 8B, the 11 9 1 32 peptide does not perturb FITC In contrast the 1 12 12 5 peptide induces a fluorescence ... sequences Peptide 15 9 19 3 Kd ELISA Peptide 15 9 19 3 Kd fluorescence Cofilin Kd Reference for cofilin Actin G Actin F 1 10 18 28 84 10 3 1 12 12 5 11 9 1 32 347–365 338–348 360–3 72 355–375 1. 3 mM ND No binding...

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... ns-LTPs 20 000 15 000 10 000 5000 -Molar ellipticity (deg·cm2·dmol 1) B 20 000 C 20 000 15 000 10 000 5000 15 000 10 000 5000 10 [dithiothreitol] (mM) 12 Fig CD signal recorded at 22 2 nm and 10 °C ... 20 000 –30 000 19 0 20 0 22 0 24 0 25 0 Wavelength (nm) 20 000 10 20 40 60 Temperature (ºC) Fig CD spectra (A, C) and temperature scans recorded at 22 2 nm (B, D) obtained for nPar j 1 Par j in mM ... (mdeg) 20 000 10 000 15 000 20 000 –30 000 19 0 20 0 22 0 24 0 20 000 10 25 0 20 Wavelength (nm) C 40 000 D CD (mdeg) 20 000 CD (mdeg) 40 60 80 90 80 90 Temperature (ºC) –5000 10 000 15 000 20 ...

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... replicon [Con -15 (15 /1, 15 /2, 15 /3), Con -17 (17 /1, 17 /2, 17 /3) and Con -24 (24 /1, 24 /2, 24 /3)] were prepared The nine different replicon cell lines were maintained in the presence of IFN-α2b (10 00 IU/ml) ... cell line (15 -1, 15 -2 and 15 -3) are comparable to sensitive cells (Fig 6A) Similar results were obtained with 17 -1, 17 -2 and 17 -3 (Fig 6B) and 24 -1, 24 -2, 24 -3 (Fig 6C) The receptor binding studies ... radioactivity specifically bound to the cell surface at each concentration of interferon was determined http://www.virologyj.com/content/4 /1/ 89 10 11 12 13 14 15 16 17 18 19 20 Competing interests The...

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... immunodeficiency virus -1 (HIV -1) J Clin Invest 19 92, 89 :17 6 -18 3 Butler SL, Hansen MS, Bushman FD: A quantitative assay for HIV DNA integration in vivo Nat Med 20 01, 7:6 31- 634 doi :10 .11 86 /17 43- 422 X-7-354 Cite ... 7:354 http://www.virologyj.com/content/7 /1/ 354 18 19 20 21 22 23 24 25 26 27 Page of immunodeficiency virus type integration by using a specific, sensitive and quantitative assay based on real-time ... 19 93, 67 :11 69 -11 74 10 Stevenson M, Stanwick TL, Dempsey MP, Lamonica CA: HIV -1 replication is controlled at the level of T cell activation and proviral integration Embo J 19 90, 9 :15 51- 1560 11 ...

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... Cengage Inc 15 Chapter TRAIT AND FACTOR THEORY Step 1: Gaining self-understanding Step 2: Obtaining knowledge about the world of work Step 3: Integrating information about self (Step 1) and the world ... Psychological COPYRIGHT © 20 14 Brooks/Cole*Wadsworth Publishing Company A division of Cengage Inc 16 Personality Factors Inventory 17 OBTAINING KNOWLEDGE ABOUT THE WORLD OF WORK Step 2: Types of Occupational ... promoting health and well-being Justice – Fairness in dealing with clients and other professionals Fidelity – Honoring commitments to clients, colleagues, and students COPYRIGHT © 20 14 Brooks/Cole*Wadsworth...

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... Acute cortical damage to auditory processing structures might be assessed objectively in a complementary manner, via studies of the MMN [10 3] 1 52 10 11 12 13 14 15 16 17 18 Closing Remarks Each ... Revista de Neurologica 20 02; 34 :10 17 -1 020 10 3 Näätänen R, Escera C Mismatch negativity: clinical and other applications Audiology and Neurootology 20 00; 5 :10 5 -11 0 Figures Figure Archetypical waveform ... Science 19 84; 22 5:483-486 91 Van Der Stelt O, Geesken R, Gunning WB, et al P3 scalp topography to target and novel visual stimuli in children of alcoholics Alcohol 19 98; 15 :11 9-36 92 Porjesz B And...

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... việt 1A 25 1B 25 Khối 50 To n 25 25 50 Mĩ thuật 25 25 50 TNXH Đạo Đức 25 25 25 25 50 50 Âm nhạc 25 25 50 2A 2B Khối Tiếng Anh 24 24 48 24 24 48 24 24 48 24 24 48 24 24 48 24 24 48 3A 3B Khối 28 28 ... KHỐI SS 62 11 4 52 Tổng 62 11 4 52 Tổng 62 11 4 52 Tổng 62 11 4 Tổng 52 62 11 4 52 Tổng HOÀN THÀNH SL % 52 Tổng HOÀN THÀNH TỐT SL % CHƯA HOÀN THÀNH SL % 62 11 4 Đạo Âm Kỹ Thể Mỹ Khoa, sử, địa 18 DANH ... STT MÔN KHỐI SS 62 11 4 52 Tổng 62 11 4 52 Tổng 62 11 4 52 Tổng 62 11 4 52 Tổng 62 11 4 Tổng HOÀN THÀNH SL % 52 Tổng HOÀN THÀNH TỐT SL % CHƯA HOÀN THÀNH SL % 11 4 Đạo Âm Kỹ Thể Mỹ 17 KẾT QUẢ CÁC MÔN...

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... www.heinlenrights.com fax 1- 800-730 -22 15 phone 1- 800-730 -22 14 Heinle & Heinle Publishers 20 Park Plaza Boston, MA 0 21 16 UK/EUROPE/MIDDLE EAST: Cengage Learning Berkshire House 16 8 -17 3 High Holborn London, WC1V 7AA, ... Speaker 1: Speaker 2: Speaker 1: Speaker 2: Speaker 1: Speaker 2: Speaker 1: Speaker 2: Speaker 1: Speaker 2: Speaker 1: Speaker 2: Speaker 1: Speaker 1: Speaker 2: Speaker 1: Speaker 2: Speaker 1: ... page 22 3 x Listening 2: Talking About Pets, pages 21 7 21 8   i h c e g b c a c c Simple Past study knocked asked talk x Vocabulary Building, pages 21 9 -22 0 frozen: to break: a cry: to struggle: to...

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... Dual-Homed Devices NPE 11 NPE10 ge2/4.4 gi3/0/0/0 primary NPE 12 fa1/0.4 ge2/4 .2 backp gi3/0/0 /11 ge1/3.4 72a fa1/0 .2 NPE14 ge1/3 .2 Note 19 1978 Figure 4 -2 The configurations on the primary and backup interfaces ... fa1/0.4 description 72a to npe 12 – bridged encapsulation dot1q ip address 10 0.4 .1. 12 255 .25 5 .25 5.0 interface fa1/0 .2 description 72a to npe 12 - xconnect encapsulation dot1q ip address 10 0 .2. 1. 12 ... ge2/4.4 gi3/0/0/0 primary NPE 12 fa1/0.4 ge2/4 .2 backp gi3/0/0 /11 ge1/3.4 72a fa1/0 .2 NPE14 ge1/3 .2 19 1978 Figure 4-3 This is the configuration at NPE10: interface ge2/4.4 description npe10 to...

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... ˚ 2d2 (A2) R factor Wild-type CeMT -1 KO S S O S 4 3.3 2. 49 2. 53 1. 98 2. 52 0. 026 0. 017 0. 015 0. 013 74.3 48.6 40.5 O O 4 2. 00 2. 00 0. 010 0. 015 39 .1 30.9 CeMT -2 KO S 2. 48 0. 028 78.8 3.3 2. 51 1.98 ... Journal 27 7 (20 10 ) 25 31 25 42 ª 20 10 The Authors Journal compilation ª 20 10 FEBS 25 33 C elegans metallothioneins discriminate between metals S Zeitoun-Ghandour et al MT isoform log KZn 12 . 0 ± 0 .1 12 . 0 ... observed in spectra of the CeMT -1 knockout mtl -1 (tm1770) and the CeMT -1 A CeMT -2 KO Normalised signal CeMT -1 KO Wildtype 26 700 26 710 26 720 26 700 26 740 26 780 26 820 26 860 Energy (eV) B Double...

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... 12 7 ± 15 735 ± 11 4 11 6 ± 44 6 61 ± 11 7 714 ± 52 13 40 ± 24 1 1960 ± 335 14 6 ± 11 > 5000 13 6 ± 19 > 5000 > 5000 > 5000 > 5000 > 5000 ND ND > 5000 12 8 3 ± > 5000 13 43 ± > 5000 > 5000 ND > 5000 12 9 1 ... GST-hEAG (1 20 6)_F151NL 15 4N GST-hEAG (1 20 6)_F151SÆL154SÆL158S GST-hEAG(674–867) GST-hEAG(674–867)_F 714 SFÆ 717 S GST-hEAG(649–867) GST-hEAG(649–867)_F 714 SÆF 717 S GST-hEAG(649–867)_F 714 SÆF 717 SÆL674NÆI678N ... respect to the wild type, but had no resemblance of mutant hEAG1DN Vm values were: ) 21 .7 ± 2. 1 mV for hEAG_F151NÆL154N and )22 .4 ± 3.5 mV for hEAG_R675NÆR677NÆR681NÆK682N As can be seen in Fig 5A,...

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... 0.88 1. 90 0.94 ± ± ± ± ± ± 4 .29 4 .25 2. 44 5 .20 3 .25 88.6 16 1.0 53.4 48 .2 945.0 ND 1. 00 1. 01 1.76 0.83 1. 32 0.05 0.03 0.08 0.09 0.005 ND 1. 00 0. 51 0.97 ± ± 2. 35 2. 90 2. 25 ± ± 23 .50 56.86 23 .20 ND ... Ala 31 des- (2, 3)-Ala 31 Leu60 Ala31Leu60 IGF-II and analogues IGF-II Des- (1 6) Arg6 Leu27 Des- (1 6 ,10 )-Leu27 kd ´ 10 )3 (1/ s) Kd ´ 10 )9 (M) Relative Kd 2. 70 2. 52 3.60 3.65 2. 89 ± ± ± ± ± ± 1. 16 1. 07 ... 40 F 18 0 13 0 10 0 70 20 10 50 450 850 0 50 450 850 G C 18 0 50 10 0 30 10 20 50 450 850 D 50 450 850 H 18 0 50 10 0 30 10 20 50 450 850 Time (s) 50 450 Response (RU) Response (RU) Ó FEBS 20 02 Fig BIAcore...

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... 69 gstk -1 (zk1 320 .1) B AA position rGSTK1 GSTK -1 GSTK -2 4 62 51 150 1 82 15 1 gstk -2 (d2 024 .7) E Petit et al 380 599 50 469 10 0 15 0 20 0 C that C elegans ZK1 320 .1 and D2 024 .7 genes belong to the kappa ... temperature was programmed from 11 0 to 22 0 °C at a rate of °CÆmin )1 and the carrier gas was hydrogen (0.5 bar) The injector and detector were maintained at 22 5 and 24 5 °C, respectively Finally, ... composition of control and gstk -1, gstk -2 and double gstk -1( RNAi) and gstk -2( RNAi)-treated animals (see also Tables S1–S4) Depletion of both gstk -1 and gstk -2 leads to a decrease in the 18 :1w7 fatty acid,...

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