basic concepts in clinical practice

... practiced Summary In this article, we outline a model for thinking about how organizations can influence community clinicians’ decision-making about becoming or remaining involved in clinical research ... strategies outlined above are suitable for all types of organizations that might be interested in supporting clinician involvement in clinical research, and may not apply to all clinical settings Table ... should increase the likelihood that clinicians will choose – in a sustained way – to incorporate into their practices research that could inform clinical questions, methods, analyses, and clinical...

Ngày tải lên: 10/08/2014, 10:23

... is linked to: (i) the presence of inlet, sinusoidal and outlet sphincters composed of sinusoidal lining cells bulging into the lumen; (ii) transient leukocyte plugging; (iii) variations in the ... acclaim I certainly found it useful in my own practice In the second edition the focus on clinical medicine was strengthened, as it has been in this edition, and the emphasis in the basic science ... an accessory vein, with a larger part of the right dorsal area of the liver being drained by right inferior veins and branches of the middle hepatic vein In the era of increasing surgical demand...

Ngày tải lên: 06/03/2014, 09:21

... Extraarticular Intraarticular involving radiocarpal joint Intraarticular involving distal radioulnar joint Intraarticular involving radiocarpal and distal radioulnar joint I III II IV V VI VII VIII ... line passing from anterior body through the inferior subchondral plate Stage IV: Inferoposterior margin displaced

Ngày tải lên: 06/03/2014, 18:20

Ngày tải lên: 15/03/2014, 09:20

... Caldesmon Filamin Vinculin Calponin Calponin Metavinculin Smoothelin Talin Synamin Paxillin Paranemin Tensin Myosin (type II) Tropomyosin -actinin Calponin -actinin Integrins Plectrin After Small ... domain Adherens junction Caveolar domain Actin (smooth muscle) Actin (nonmuscle) Actin (nonmuscle) Actin (nonmuscle) Actin (nonmuscle)? Desmin Filamin Dystrophin (or vimentin) Calponin Caveolin ... studies showing that stimulants such as noradrenaline (norepinephrine) increased tone following depolarization with potassium were originally interpreted as indicating receptor-linked inXux of Ca2+,...

Ngày tải lên: 22/03/2014, 20:21

... antigen (CLA)-bearing T cells home to sites in the skin layers and reinforce the innate system in resolving the inciting injury Through an increasingly sophisticated understanding of this immune ... allergens, including the skin, respiratory tract, and intestine [28] They are best understood for their role in triggering inflammation, degranulating in response to the cross-linking of FcεR ... after inflammation and nerve injury J Clin Invest 115:2393–2401 Obreja O, Rukwied R, Steinhoff M, et al (2006) Neurogenic components of trypsin- and thrombin-induced inflammation in rat skin, in...

Ngày tải lên: 22/03/2014, 21:20

... important in maintaining normal epithelial integrity Mice deficient in intestinal epithelial cell IKK␥ (NEMO) were generated by crossing mice carrying LoxP-flanked NEMO alleles with villin Cre transgenics ... effects on the intestinal epithelium IL-13 is involved in induction of fibrosis in this and other models of in ammation by inducing the IL-13 receptor a(2) in macrophages, then signaling via this ... learned in basic science research and is leading to a “personalized medicine” approach for managing in ammatory bowel diseases and is bringing the potential of prevention into view As Editors, our intention...

Ngày tải lên: 22/03/2014, 21:20

... Figure Outline of a PACS infrastructure comprising the most common components in an imaging institution Figure Evolution of PACS research and current trends Medical Imaging in Clinical Practice ... of art in museums and images in the internet, but we know of no use-case in a clinical context Other, more complex types of query can be expressed over these Medical Imaging in Clinical Practice ... DICOM and Clinical Data Mining in a Small Hospital PACS: A Pilot Study In Communications in Computer and Informa‐ tion Science; 2011: Springer Berlin Heidelberg p 254-263 [37] Medical Visual Information...

Ngày tải lên: 23/03/2014, 05:21

... an instructor of Occlusion, Pre -Clinical Fixed Prosthodontics, Integrated Clinical Sciences and maintains a part-time private practice in San Francisco, California Marina Wasche DDS, BS Marina ... opening and in the closing movements? In general, a late opening and early closing joint sound indicates a greater dysfunctional diagnosis than an early opening, late closing joint sound This information ... brain is associated with verbal, logical, and analytical thinking It excels in naming and categorizing things, symbolic abstraction, speech, reading, writing, and arithmetic The right brain,...

Ngày tải lên: 29/03/2014, 11:20

... Figure Outline of a PACS infrastructure comprising the most common components in an imaging institution Figure Evolution of PACS research and current trends Medical Imaging in Clinical Practice ... of art in museums and images in the internet, but we know of no use-case in a clinical context Other, more complex types of query can be expressed over these Medical Imaging in Clinical Practice ... DICOM and Clinical Data Mining in a Small Hospital PACS: A Pilot Study In Communications in Computer and Informa‐ tion Science; 2011: Springer Berlin Heidelberg p 254-263 [37] Medical Visual Information...

Ngày tải lên: 30/03/2014, 09:20

... opposing the folding of proteins BG McGraw-Hill: Gilbert, Basic Concepts in Biochemistry, JN 5036 • 18 • Basic Concepts in Biochemistry When a protein folds, most of the hydrophobic side chains ... “driving force” for protein folding, protein–protein interactions, and protein– ligand interactions (Fig 2-1) The driving force for a chemical reaction is what makes it happen It’s the interaction ... observed in proteins is there to keep from losing hydrogen bonds BG McGraw-Hill: Gilbert, Basic Concepts in Biochemistry, JN 5036 • 12 • Basic Concepts in Biochemistry A hydrogen bond is an interaction...

Ngày tải lên: 08/04/2014, 12:40

... opposing the folding of proteins BG McGraw-Hill: Gilbert, Basic Concepts in Biochemistry, JN 5036 • 18 • Basic Concepts in Biochemistry When a protein folds, most of the hydrophobic side chains ... “driving force” for protein folding, protein–protein interactions, and protein– ligand interactions (Fig 2-1) The driving force for a chemical reaction is what makes it happen It’s the interaction ... observed in proteins is there to keep from losing hydrogen bonds BG McGraw-Hill: Gilbert, Basic Concepts in Biochemistry, JN 5036 • 12 • Basic Concepts in Biochemistry A hydrogen bond is an interaction...

Ngày tải lên: 06/06/2014, 17:58

... widely implemented in clinical practice This may be explained by the initial lack of convincing data regarding the effectiveness of standardized HRQoL measurement in actually improving HRQoL or psychosocial ... physicians in the experimental group requested the information in 92% of the consultations, discussing it with their patients in 58% of the consultations They indicated finding the HRQoL information ... can instantly be accessed by clinicians The aim of the present study was to gain more insight in the practical and attitudinal feasibility problems encountered during the process of implementing...

Ngày tải lên: 18/06/2014, 19:20

... EFVcontaining 3- or 4-drug combinations in a blinded fashion found the EFV-based regimens to be more effective at suppressing viral replication and maintaining that suppression, regardless of baseline ... for this combination of drugs is not due to an adverse pharmacologic interaction Nonthymidine-Containing ("TAM-Sparing") t-NRTI Regimens as Initial ART Clinical trials that have investigated ... caused many clinicians to be cautious, and often confused, about using t-NRTI in current practice Recently, t-NRTI combinations that contain tenofovir (TDF) have been investigated in prospective...

Ngày tải lên: 20/06/2014, 08:20

... widely implemented in clinical practice This may be explained by the initial lack of convincing data regarding the effectiveness of standardized HRQoL measurement in actually improving HRQoL or psychosocial ... physicians in the experimental group requested the information in 92% of the consultations, discussing it with their patients in 58% of the consultations They indicated finding the HRQoL information ... can instantly be accessed by clinicians The aim of the present study was to gain more insight in the practical and attitudinal feasibility problems encountered during the process of implementing...

Ngày tải lên: 20/06/2014, 16:20

... just beginning In such instances, the experiences related to more common tumor types may inform trials on these more rare clinical entities Interest in neoadjuvant chemotherapy also intensifies ... FU, 5-flourouracil; adr, adriamycin; cyc, cyclophosphamide; epi, epirubicin; cis, ciplatin; doc, docetaxel; dox, doxorubicin; vinc, vincristine; vino, vinorelbine; tam, tamoxifen; pac, paclitaxel ... accelerated growth in the residual tumor focus within 24hrs The labeling index and growth fraction were increased with a decrease in tumor doubling time There was minimal change in DNA synthesis...

Ngày tải lên: 27/06/2014, 13:20

... DEKKER, INC NEW YORK BASEL HONG KONG Page ii Library of Congress Cataloging -in- Publication Data Intravenous immunoglobulins in clinical practice / edited by Martin L Lee, Vibeke Strand p cm Includes ... transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing ... Extrapolation of the final slope -b1 to the ordinate and intercept C0 are explained in the text Both the α and β phases may be influenced by intrinsic IgG synthesis of the patient and by extrinsic carryover...

Ngày tải lên: 29/06/2014, 09:20

... maintain boundaries between distinct sets of proteins in each domain A sodium channel domain is also maintained at nodes of Ranvier between myelin sheaths (b) Transverse section through the internodal ... complementary-determining regions (CDR), Light chain Heavy chain Antigenbinding site VH Complementarydetermining regions (CDR) VL CH1 CL CH2 FC region Fc receptor complement binding site CH3 Fig ... myelin membrane during development This glycoprotein is localized to the inner loop in mature myelin where it can interact with surface lipids or proteins from the axon One such interacting protein...

Ngày tải lên: 10/08/2014, 00:20

... Pettinelli and McFarlin, 1981) Myelin basic protein is one of these proteins T cells reactive with myelin basic protein can be demonstrated in individuals with MS and in normal controls The myelin-specific ... four clinical courses that are routinely used in practice (Lublin and Reingold, 1996) This empirical classification, in agreement with natural history studies, distinguishes relapsingremitting ... gadoliniumenhancing lesion (not at the site involved in the original clinical event) is needed; if no enhancing lesion is present, a follow-up scan with new T2- or gadolinium-enhancing lesion in...

Ngày tải lên: 10/08/2014, 00:20