... Yves Sandoz eds., 1989) Examples are the Magna Carta of 1215 the U.K Bill of Rights of 1688, the French Declaration of the Rights of Man and of the Citizens of 1789, the U.S Bill of Rights of 1791 ... Laws and Customs of War on Land and its annex: Regulations concerning the Laws and Customs of War on Land The Hague, 29 July 1899; Convention (IV) respecting the Laws and Customs of War on Land and ... situations of military violence between or among states has been through the application of rules of the law of war The development of rules on the conduct of hostilities, means and methods of warfare...
Ngày tải lên: 11/10/2016, 21:35
... create signiÞcant changes in the genetic makeup of plants and animals due to the random recombination and sorting of thousands of genes As a result of intervention by people, the hybrid seed corn ... ßax, and canola; and virus-resistant squash, papaya, and potato Advantages of insect- and virus-resistant crops include improved yields and reduced use of pesticides An additional beneÞt of Bt ... estimated that 24% of the corn and almost 70% of the soybeans and cotton grown in the U.S in 2001 were GM varieties Examples of GM crops include insectresistant (Bt) corn, cotton, potato, and tomato;...
Ngày tải lên: 25/10/2013, 21:20
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... homologs of Caenorhabditis elegans synMuvB proteins and is composed of p130, E2F4 ⁄ and DP1 ⁄ and a module containing the MuvB proteins Lin-37, Lin-52, Lin-54 and chromatinassociated Lin-9 and Lin-53 ... A Muller and K Engeland ¨ reduces p300-dependent activation [58] Recruitment of p300 HAT on the cyclin A and Cdc2 promoters may also be in accordance with activation and histone H3 and H4 acetylation ... Muller and K Engeland ¨ More information is available on the binding of E2F and pocket proteins to CDE ⁄ CHR promoters There are several hints for a functional connection of E2F4 binding and CDE-dependent...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
... absence of nucleotides (Table 1) The rate of CTP synthesis was dramatically inuenced by the presence of GTP, and 20 and 41-fold increases in kcat were obtained with GTP concentrations of 0.1 mM and ... basis of the kinetic constants in Table 1, and those obtained for the glutaminase reaction in the presence of 0.1 mM each of UTP and ATP-cS (data not shown) Apparently, the value of Ka, kcat,1 and ... activation of the glutaminase activity in the presence of 0.1 mM (open circles) or mM (closed circles) each of UTP and ATP-cS (C) GTP activation of CTP synthesis at 0.1 mM each of UTP and ATP L...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx
... concentrations of cofactor (Finf) were: F0 = 125 ± and Finf =65 ± for the wild-type enzyme; F0 = 139 ± and Finf = 66 ± for L85A; F0 = 122 ± and Finf = 63 ± for L276; and F0 = 103 ± and Finf = 73 ... and spectral properties of wild-type and mutant apo- and holoenzymes Quaternary structure analysis The subunit assembly of apo- and holo-forms of wildtype and mutant eSHMTs was characterized by ... consequences of the mutations on the native structure of eSHMT were evaluated by analyzing and comparing the ultracentrifuge sedimentation, cofactor binding, catalytic and spectral properties of wild-type...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
... establish the importance of GSK3 in the acute regulation of glucose transport in terms of its regulatory control of GS in muscle and fat cells we have investigated the effects of Li and the anilinomaleimide, ... regulation of GSK3 and GS To further understand the effects of Li and SB-415286 on cell signalling events we assessed their effects and that of insulin on p70S6K, PKB, p42/p44 MAP kinases, GSK3 and ... and myotubes with antibodies against GSK3a and b Fig 1B shows that whilst preadipocytes express both GSK3 isoforms, the abundance of the b isoform declines by 85%, whereas that of the a isoform...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx
... up-regulation of glucokinase and a down-regulation of glucose-6-phosphatase gene expression, suggesting that this biofactor may also be involved in balancing the uptake and release of glucose from the ... saturation ensured complete elimination of signals from outside of the volume of interest The localized signals of glycogen and glucose were acquired with spectrometer offset set to 100 p.p.m (64 scans ... enrichments of glycogen C1 and C6, and the net glycogen synthesis rate were measured, Eqns (1), (2) and (3) can be ð6Þ Initially, the enrichment of glycogen is low ([13G1yc6]/ [Glyc] < 1) and the...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
... influence the shape and volume of the acyl binding pocket and thereby alter the binding mode and affinity of the enzyme for PAA and derivatives thereof, while maintaining the hydrophobicity of the binding ... 6-APA, hydrolysis of the acyl enzyme still occurs [11,12] Fitting Eqn (4) to the data yielded values for KN of 37 mM and 69 mM and for (Vs/Vh)max of and 10 for the wild-type and bF24A, respectively ... residues and interactions influence the performance of PA in the formation of semisynthetic b-lactam antibiotics The X-ray structure of the complex of PA with PAA shows that the acyl binding site of...
Ngày tải lên: 17/03/2014, 23:20
The role of floating-rate bank loans in institutional portfolios pdf
... Bureau of Economic Research, Federal Reserve Bank of St Louis, U.S Department of the Treasury Indexes are unmanaged and cannot be invested in directly Past performance is not indicative of future ... 01 and Dec 07–Jun 09), and blue-shaded areas indicate rising rate periods (Sep 92–Jan 95; Oct 98–Oct 00; and Jan 04–Feb 07) Sources: National Bureau of Economic Research, Federal Reserve Bank of ... Louis and U.S Department of the Treasury Data is historical and is not indicative of future results In these rising interest rate environments, bank loans have yielded positive returns and outperformed...
Ngày tải lên: 22/03/2014, 17:20
Perceptions About Network Security: Survey of IT & IT security practitioners in the U.S. pptx
... 29% Lack of leadership and accountability Complexity of security operations 15% 48% Availability of enabling technologies Employee awareness 18% 33% Policies and procedures Monitoring and enforcement ... Chief Financial Officer General Counsel 2% 2% Chief Information Officer Chief Technology Officer 53% 5% Chief Information Security Officer Compliance Officer 19% 2% Chief Privacy Officer Human ... years of experience in either the IT or IT security fields Twenty-one percent of respondents are female and 79 percent male Table shows the position levels of respondents As shown, 62 percent of...
Ngày tải lên: 28/03/2014, 22:20
FUTURE OF THE NUCLEAR SECURITY ENVIRONMENT IN 2015 pptx
... principle of equal security, keeping in mind both the nuclear and non-nuclear aspects of the picture, the placement of elements of forward base deployment, and the presence or absence of any hostile states ... raise the level of workplace discipline of staff and ensure that they follow the rules for handling nuclear materials, and to raise control over the aspects of the work and functioning of physical ... at the highest levels, projects of appropriate size and scale for the tasks at hand and the resources of those involved, and sustained engagement by qualified and dedicated individuals are well-proven...
Ngày tải lên: 29/03/2014, 18:20
Báo cáo khoa học: The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates potx
... two-fold higher than that of CTP and GTP, and the ratio of dATP and dTTP to dCTP and dGTP was also : [16,17] This fact is in accordance with the genome composition of Mollicutes, which has a ... and eluted with 0.5 mL of 0.1 m HCl and 0.2 m KCl, and then 2.5 mL of scintillation fluid was added and the radioactivity counted The Rf values for ATP, ADP, AMP, dCTP, dCDP and dCMP in 0.2 NaH2PO4 ... Table The effect of ATP concentration on the equilibrium concentration of labelled adenine nucleotides The initial concentration of [3H]AMP was 100 lM and the concentration of MgCl2 was 10 mM...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism pdf
... version of the manuscript, Dr R.M de Lederkremer, and Dr Oscar J Opezzo for the discussion of results The contribution of Dr Marı´ a A Dagrosa and Dr Silvia Moreno in some experiments and the ... submerged in a solution of sulfuric acid 5% in ethanol; (b) dried and (c) heated at 120 °C in a stove, until the appearance of brown spots, typical of carbohydrates The silica of the second plate, ... 105 000 g supernatant fraction with an equal volume of chloroform DNA and RNA were ruled out as possible components of the inhibitor, as DNAse and RNAse did not affect the inhibitory capacity (data...
Ngày tải lên: 30/03/2014, 14:20
the role of u s engineering schools in development assistance doc
Ngày tải lên: 31/03/2014, 14:20
báo cáo hóa học: " The role of cumulative physical work load in symptomatic knee osteoarthritis – a case-control study in Germany" potx
... kneeling and squatting as well as to lifting and carrying of loads and symptomatic knee osteoarthritis grade 2: definite osteophytes and possible narrowing of joint space; Subjects and methods ... questionnaire and observation ratings of 0.49 for frequency of lifting, carrying, and transferring 6–15 kg Concerning the frequency of lifting, carrying, and transferring 6–15 kg, the self-assessed and ... Power of the study Calculation of the power of the study was based on an expected prevalence of kneeling of 9% among the male population according to Seidler et al [8] To detect an odds ratio of...
Ngày tải lên: 20/06/2014, 00:20
báo cáo khoa học: "The role of 18F-FDG-PET/CT in the preoperative staging and posttherapy follow up of gastriccancer:Comparison with spiral CT" docx
... staging of gastric cancers is spiral CT But as an anatomic imaging method, CT is known to have a low sensitivity and spesificity at N staging of the Page of Table The rates of concordance and discordance ... reported, sensitivity and spesificity of PET in the diagnosis of liver metastasis was 85% and 74% respectively, 67% and 88% in lung metastasis [15] In our study, in 1/4 of the Group patients ... of the study and drafted the manuscript MA and CS performed the statistical analysis, documentation of the data, literature analysis and participated in drafting the manuscript OK conceived of...
Ngày tải lên: 09/08/2014, 02:20
Báo cáo y học: "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models" pps
... interrelationship of IL-17 with receptor activator of NF-κB ligand (RANKL), IL-1, tumor necrosis factor (TNF) and the modulatory role of IL-4 and osteoprotegerin (OPG) is presented OC, osteoclast positive and ... [18] (Table 1) The expression pattern of these new receptors seems to be more cell/tissuespecific than that of the IL-17R, and the ligand specificities of many of these receptors have not been established ... inducer of RANKL and that the IL-17-induced promotion of bone erosion is strongly mediated by RANKL Interrelation between IL-17 and IL-1/TNF Overexpression of IL-17 in the mouse knee joint of CIIimmunized...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "The role of tumor necrosis factor-alpha in systemic lupus erythematosus" pdf
... (IL)-1 and IL-6, respectively (blue lines) TNF also exerts a wide variety of immunoregulatory (left) and pro-inflammatory actions: TNF is involved in the maturation of dendritic cells (DC) and activates ... arthritis, pneumonitis, and skin disease of moth-eaten mice [18] and nephritis and leukopenia in the C3H.SW mouse [19], two additional lupus models Of particular interest, administration of low-dose TNF ... and IL-18 for cytotoxic T cells (Tc) On the other hand, chronic TNF exposure leads to the disassembly of T-cell receptors (TCR), thus inhibiting T-cell responses, and induces the expression of...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo y học: "Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints" potx
... complete loss of articular cartilage tissue and degeneration of the menisci The cartilage of the lateral compartment and the patellofemoral joint was affected with fibrillation and fissuring ... of collagen fibers and formation of the triple helices The hydroxylation of proline residues is essential for the formation of intramolecular hydrogen bonds and contributes to the stability of ... requirement of adequate levels of HIF-1 for the viability of chondrocytes and for the maintenance of the integrity of hypoxic articular cartilage One has to consider, however, that surplus levels of HIF1α...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: " Role of taurine on acid secretion in the rat stomach" ppsx
... designed and supervised by RHL and LHT Experiments were performed by KHH and CCC Analysis of the data was performed by KHH, CCC and JDH LHT drafted the manuscript and all authors read and approved ... Effect of various doses of taurine-induced acid secretion in the isolated stomach (A) Dose-dependent curve of taurine-induced acid secretion (B) Correlation between various doses of taurine and ... level of cAMP Fourth, the presence of taurine-containing cells in the rat stomach is confirmed, as indicated by CSAD- and taurine-positive cells We found the presence of taurine-containing cells and...
Ngày tải lên: 10/08/2014, 05:21