bacteremia sepsis and septic shock

... Recommendations Assessment, Development and Evaluation criteria; guidelines; infection; sepsis; sepsis bundles; sepsis syndrome; septic shock; severe sepsis; Surviving Sepsis Campaign Sponsoring organizations: ... severe sepsis (acute organ dysfunction secondary to documented or suspected infection) and septic shock (severe sepsis plus hypotension not reversed with fluid resuscitation) Severe sepsis and septic ... resuscitation of severe sepsis and septic shock (grade 1B) We recommend against the use of hydroxyethyl starches (HES) for fluid resuscitation of severe sepsis and septic shock (grade 1B) (This...

Ngày tải lên: 31/03/2014, 13:20

... non-neutropenic patients with sepsis and septic shock [6,9] that also observed higher sFlt-1 levels in patients with septic shock, and that sFlt-1 could be a useful biomarker for sepsis severity Furthermore, ... citokynes in sepsis [6] However, no difference in neutrophil and platelet counts could be demonstrated between patients with non-complicated sepsis and septic shock at fever onset (Table 1), and no ... malignancies and post-chemotherapy FN that evolve to septic shock present higher levels of sFlt1 and VEGF-A than patients with non-complicated sepsis, and that levels of these biomarkers correlate with sepsis...

Ngày tải lên: 18/06/2014, 19:20

... non-neutropenic patients with sepsis and septic shock [6,9] that also observed higher sFlt-1 levels in patients with septic shock, and that sFlt-1 could be a useful biomarker for sepsis severity Furthermore, ... citokynes in sepsis [6] However, no difference in neutrophil and platelet counts could be demonstrated between patients with non-complicated sepsis and septic shock at fever onset (Table 1), and no ... malignancies and post-chemotherapy FN that evolve to septic shock present higher levels of sFlt1 and VEGF-A than patients with non-complicated sepsis, and that levels of these biomarkers correlate with sepsis...

Ngày tải lên: 20/06/2014, 03:20

... infection, and several terms were used Severe Sepsis and Septic Shock – Understanding a Serious Killer interchangeably: septicemia, sepsis, sepsis syndrome and septic shock In clinical practice sepsis ... and 66.2% in sepsis, severe sepsis and septic shock, respectively However the related mortality to infection was quite a few lower (7.7%, 16.7% and 30.1% in sepsis, severe sepsis and septic shock, ... of sepsis Further evidence is needed to support changes in the current definitions of sepsis Incidence of severe sepsis and septic shock The epidemiology of sepsis, severe sepsis and septic shock...

Ngày tải lên: 27/06/2014, 13:20

... between lactate clearance and biomarkers of pro- and anti-inflammation, coagulation, apoptosis; and further with multiorgan dysfunction and mortality in severe sepsis and septic shock These findings ... response in severe sepsis and septic shock rather than a terminal event Future studies examining the pathogenic mechanisms or novel therapies for severe sepsis and septic shock should include ... biomarker activity of inflammation, coagulation, and apoptosis and the subsequent relationship to organ failure and outcome in early severe sepsis and septic shock Page of 11 acute pulmonary edema, status...

Ngày tải lên: 11/08/2014, 08:22

... RVEF in survivors of septic shock than in nonsurvivors The question requires further study Patients with sepsis and septic shock can show resistance to the vasopressor and inotropic effects of catecholamines ... dilation and drop in diastolic blood pressure in response to a dobutamine stress test all predict survival in septic patients [31] Etiology of myocardial depression in sepsis and septic shock Myocardial ... with septic shock is still directed towards re-establishing organ and tissue perfusion and oxygen delivery by fluid resuscitation and inotropic support, ongoing research aimed at understanding...

Ngày tải lên: 12/08/2014, 19:21

... particularly in sepsis, septic shock and burns patients Competing interests None declared Acknowledgement The research of ICC van der Horst was supported by a generous grant from the Netherlands Heart ... glucoseinsulin-potassium (GIK) in human septic shock Crit Care Med 1985, 13:566-570 Mauritz W, Schindler I, Zadrobilek E, Sporn P: Glucose-potassium-insulin in hypodynamic septic shock Anaesthesist 1986, 35:623-627 ... large randomized study to determine its effectiveness once and for all [12] Recently, the Glucose–Insulin–Potassium Study (GIPS) [13] reached its conclusion In that study 940 patients were randomly...

Ngày tải lên: 12/08/2014, 19:21

... was challenged, and the definitions of sepsis, severe sepsis and septic shock were maintained [7] The second factor was the lack of an agreed severity of illness scoring system for sepsis patients ... conditions such as sepsis, and liver transplantation and long-stay ICU patients [13,14] If these systems are proved to predict accurately mortality in severe sepsis and septic shock, then they ... between March 1999 and 31 August 2001 meeting the definitions of severe sepsis and septic shock in the first 24 hours of ICU admission Severe sepsis is defined as the presence of sepsis associated...

Ngày tải lên: 12/08/2014, 19:22

... or septic shock (sepsis group) were enrolled and compared with patients admitted without sepsis (control group) Patients in the sepsis group were those in whom severe sepsis and septic shock was ... International Sepsis Definitions Conference [21]: patients with severe sepsis were those admitted with sepsis complicated by organ dysfunction; and patients with septic shock were those with sepsis and ... had nonsevere sepsis on admission From the 697 patients included in the study, 305 were admitted for severe sepsis or septic shock (sepsis group) and 392 were admitted without sepsis (control...

Ngày tải lên: 12/08/2014, 20:20

Ngày tải lên: 12/08/2014, 23:24

... Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock Crit Care Med 2004, 32:858-873 Pasteur L: Septicemie puerperale Bulletin de l’Academie de Medecine 1879, ... Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis Crit Care Med 1992, 20:864-874 Labandeira-Rey M, Couzon F, Boisset S, ... survival following bacteremia or fungemia Jama 1995, 274:807-812 Brun-Buisson C, Doyon F, Carlet J: Bacteremia and severe sepsis in adults: a multicenter prospective survey in ICUs and wards of 24...

Ngày tải lên: 13/08/2014, 10:20

... to 10 days; the minimum and maximum were days and 32 days, respectively) On inclusion, the characteristics of the 152 cases included severe sepsis (34 [22%]) and septic shock (118 [78%]) The mean ... observation period for both cases and controls began days before the onset of infection, and for the cases it lasted until period the beginning of severe sepsis or septic shock Page of (page number ... nonsteroidal anti-inflammatory drugs (NSAIDs) and those not using these drugs Log-rank test: P = 0.02 shock However, in patients with severe sepsis or septic shock we observed that NSAID use is associated...

Ngày tải lên: 13/08/2014, 16:20

... in critically ill patients with severe sepsis/ septic shock Recent international guidelines for the management of severe sepsis and septic shock (Surviving Sepsis Campaign) [16] included three important ... capillary leakage and fluid resuscitation [17], by expanding the extracellular fluid contents, may enlarge the Vd of antimicrobials in patients with severe sepsis and septic shock, such that Ct ... linezolid and moxifloxacin Clearly, TDM is invaluable in such cases Conclusions Appropriate antibiotic therapy in patients with severe sepsis and septic shock should mean prompt achievement and maintenance...

Ngày tải lên: 13/08/2014, 16:20

... from May 2005 to 15 December 2006 with sepsis were considered eligible for the study Standard definitions were used to define sepsis, severe sepsis, and septic shock [15] Exclusion criteria included ... manuscript and helped conceive the study and participated in its design and coordination JJL and AO participated in the design of the study JS helped conceive the study and participated in its design and ... wounds and measurements, drafted the manuscript, and helped perform the statistical analysis FG helped make the blister wounds and measurements and helped perform the statistical analysis VK and...

Ngày tải lên: 13/08/2014, 16:21

... program on sepsis (see below) and only the first episode of severe sepsis/ septic shock was considered in each patient The management of patients was evaluated by analysis of interventions and sepsis ... in-hospital mortality Figure shock team' activation (June 2006) in all population and in septic 'sepsispatients In-hospital mortality before (white columns) and after (black columns) 'sepsis team' activation ... practice and survival rate of patients with severe sepsis/ septic shock admitted in ICU In our model, a multidisciplinary approach and a specific team played a key role for education and for providing...

Ngày tải lên: 13/08/2014, 19:20

... indicate that subjects who are treated for severe sepsis and septic shock have a stepwise increase in mortality over Figure Figure implementation and post-implementation phases Kaplan Meier survival ... the index emerMortality rates overvisit for severe the firstor septic shock gency department visit for severe sepsis or septic shock Page of (page number not for citation purposes) Critical Care ... Incidence, treatment, and outcome of severe sepsis in ICU-treated adults in Finland: the Finnsepsis study Intensive Care Med 2007, 33:435-443 Sarnak MJ, Jaber BL: Mortality caused by sepsis in patients...

Ngày tải lên: 13/08/2014, 19:20

... 2007, 13:592-597 Bochud PY, Glauser MP, Carlet J, Calandra T: Empirical antibiotic therapy for patients with severe sepsis and septic shock In The Sepsis Text Edited by: Vincent JL, Carlet J, Opal ... a higher dosing regimen for amikacin in patients with severe sepsis and septic shock We also evaluated the impact of body weight, and specifically of an IBW-compared with a TBW-based regimen, ... each patient or his or her legal guardian Patients with a diagnosis of severe sepsis or septic shock according to standard criteria [19], in whom amikacin treatment was indicated, were consecutively...

Ngày tải lên: 13/08/2014, 20:21

... for severe sepsis and septic shock: a systematic review and meta-analysis BMJ 2004, 329:480-488 Keh D, Weber-Carstens S, Ahlers O: Adjunctive therapies in severe sepsis and septic shock: the ... methylprednisolone in the treatment of severe sepsis and septic shock N Engl J Med 1987, 317:653-658 Lefering R, Neugebauer EA: Steroid controversy in sepsis and septic shock Crit Care Med 1995, 23:1294-1303 ... Czepielewski MA: Corticosteroid therapy for severe sepsis and septic shock JAMA 2009, 302:1643-1644 Annane D: Corticosteroid therapy for severe sepsis and septic shock JAMA 2009, 302:1644-1645 Grendel T,...

Ngày tải lên: 13/08/2014, 20:22

... were accurate and precise LOD and LOQ were 0.50 and 0.75 μg/mL, respectively, for piperacillin-tazobactam, 2.00 and 5.00 μg/mL for ceftazidime, and 0.07 and 0.10 μg/mL for cefepime and Page of ... dynamic changes of the septic process that can reduce the efficacy of anti-infective treatments and consequently affect patient outcomes [6] During severe sepsis and septic shock, increased volume ... aeruginosa and other less susceptible bacteria in patients suffering from severe sepsis and septic shock • Recommended doses of meropenem resulted in adequate concentrations to cover P aeruginosa and...

Ngày tải lên: 13/08/2014, 21:20

... in sepsis and septic shock: A meta-analysis Crit Care Med 1995, 23:1294-1303 Annane D, Bellissant E, Bollaert PE, Briegel J, Keh D, Kupfer Y: Corticosteroids for severe sepsis and septic shock: ... Klastersky and colleagues [41] Schumer [31] Sprung and colleagues [43] Bone and colleagues [38] Luce and colleagues [46] Bollaert and colleagues [37] Briegel and colleagues [39] Chawla and colleagues ... colleagues Yildiz and [47]# colleagues Chawla and [39] colleagues Briegel and [37]## colleagues Bollaert and [46] colleagues Luce and [38] colleagues Bone and [43] colleagues Sprung and [31] Schumer...

Ngày tải lên: 13/08/2014, 21:21