... (19 21) -99.99 894 ,13 4 (19 41) 37 -99.99 15 2,209 (19 68) 236 -99.90 265,269 (19 34) 18 ,957 -96.84 21, 269 (19 52) -10 0.0 57,686 (19 69) 12 -99.98 1, 560 (19 23) 26 -98.33 ~20,000 (19 84) 16 -99.92 26, 611 ... antibody-producing cells T cells: TH17 differentiation Interleukin -15 (IL -15 ) Macrophages, others NK cells: proliferation T cells: proliferation Interleukin -18 (IL -18 ) Macrophages NK cells and T cells: IFN-γ ... of Adaptive Immunity Cells of the Immune System Lymphocytes 8 Antigen-Presenting Cells Effector Cells 13 13 Tissues of the Immune System Peripheral Lymphoid Organs 13 14 Lymphocyte Recirculation...
Ngày tải lên: 04/08/2016, 15:18
... interleukin 17 Nat Immunol 2005, 6 :11 33 -11 41 Miossec P: Interleukin -17 in fashion, at last: ten years after its description, its cellular source has been identified Arthritis Rheum 2007, 56: 211 1- 211 5 ... were characterized by flow cytometry and the percentage of CD11b+ cells, CD11b+Gr-1high cells, B220+ cells, CD4+ cells and CD8+ cells was analyzed Bars represent the mean net numbers of three ... Therapy Vol 11 No Kelchtermans et al Introduction IL -17 is a pro-inflammatory cytokine produced by activated CD4+ T cells distinct from Th1 or Th2 cells, designated as Th17 cells [1- 3] IL -17 promotes...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Ageing, autoimmunity and arthritis: Senescence of the B cell compartment — implications for humoral immunity" pptx
... Acknowledgments This work was supported by the National Institute of Aging (RO1 AG13983) References 10 11 12 13 14 15 16 17 18 13 8 Bovbjerg DH, Kim YT, Schwab R, Schmitt K, DeBlasio T, Weksler ME: ‘Cross-wiring’ ... cells in the absence of b cell influx from the bone marrow J Exp Med 20 01, 19 4 :11 51- 116 4 54 Globerson A, Effros RB: Ageing of lymphocytes and lymphocytes in the aged Immunol Today 2000, 21: 515 -5 21 ... early age Int Immunol 20 01, 13 :12 13 -12 21 68 Klinman DM: Similarities in B cell repertoire development between autoimmune and aging normal mice J Immunol 19 92, 14 8 :13 53 -13 58 69 Adkins B, Riley...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
... Rheum 19 84, 27 :10 10 -10 17 Cook AD, Rowley MJ, Stockman A, Muirden KD, Mackay IR: Specificity of antibodies to type II collagen in early rheumatoid arthritis J Rheumatol 19 94, 21: 118 6 -11 91 Cook ... have no competing interests References 10 11 12 13 14 15 16 17 Stuart JM, Dixon FJ: Serum transfer of collagen-induced arthritis in mice J Exp Med 19 83, 15 8:378-392 Terato K, Hasty KA, Reife RA, ... Exp Med 20 01, 19 4:3 21- 330 11 5 Matsumoto I, Staub A, Benoist C, Mathis D: Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme Science 19 99, 286 :17 32 -17 35 11 6 Basu D, Horvath...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Tumor-infiltrating effector cells of α-galactosylceramide-induced antitumor immunity in metastatic liver tumor" pdf
... http://www.jibtherapies.com/content/2 /1/ 7 8.6 0.57 Vehicle/HL 15 .2 23 .1 2.8 2 .1 3.4 0 .16 Vehicle/TIL 22.3 8.0 3.6 14 .5 0.73 30.2 2.8 16 .0% 20.0 11 .7 0.40 αGalCer/TIL 12 .4% 21. 1 αGalCer/HL 5.8 6 .1% 36.5 28.9 TCR CD4 ... 2:7 IFN-γ secretion (pg/ml) γ 10 0 Colon26 90 http://www.jibtherapies.com/content/2 /1/ 7 10 0 NIH3T3 90 80 80 70 70 60 60 50 50 40 40 30 30 20 20 10 10 0 10 :1 1 :1 10 :1 1 :1 Effector:Target Ratio Figure ... http://www.jibtherapies.com/content/2 /1/ 7 1. 1 1. 4 B220 CD80 Journal of Immune Based Therapies and Vaccines 2004, 2:7 1. 2 1. 3 Vehicle/TIL 0.4 1. 4 0.4 αGalCer/HL 0.5 0.4 2.2 αGalCer/TIL 1. 6 CD11c 3 .1 I-A Figure Flow...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: "Lung epithelium as a sentinel and effector system in pneumonia – molecular mechanisms of pathogen " pdf
... http://respiratory-research.com/content/7 /1/ 97 15 0 15 1 15 2 15 3 15 4 15 5 15 6 15 7 15 8 15 9 16 0 16 1 16 2 16 3 16 4 16 5 16 6 16 7 16 8 of MDA5 and RIG-I helicases in the recognition of RNA viruses Nature 2006, 4 41: 1 01- 105 Barnes B, ... Mody CH: Differ- Page 13 of 17 (page number not for citation purposes) Respiratory Research 2006, 7:97 94 95 96 97 98 99 10 0 10 1 10 2 10 3 10 4 10 5 10 6 10 7 10 8 10 9 11 0 11 1 11 2 11 3 ent domains of Pseudomonas ... Am J Respir Crit Care Med 19 98, 15 7 :11 65 -11 72 Page 11 of 17 (page number not for citation purposes) Respiratory Research 2006, 7:97 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29...
Ngày tải lên: 12/08/2014, 16:20
A study of the mechanisms of immunity to pasteurella haemolytica infection
... nm 0) ö I- M H CD ö 10 d ö M O ö 11 111 11 11 IIIII 11 IIIIi II1 11 111 11 I\\ CO (njo 01 eon) BoilAlowesy "d 10 sjunoo elqv , 0) ö Co ö NQ IDý ö co ÖU N Ö Ö (nia 01 gol) 13 011 , Klowee4 A io siunoo ... ELISA test of 16 6 -16 7 16 8 -17 1 Discussion DISCUSSION CONCLUDING Mechanisms of 17 2 -19 0 immunity to P in haemolytica 17 4 -1. 81 sheep Models of P haemolytica infection in mice 18 2 -19 0 19 1- 212 Bibliography ... vaccine in 11 8 -11 9 12 0 -12 1 6Effect with Experiment of treatment 24 hours before Carovax with challenge B188 upon the growth E coli of the organism in the livers of mice 12 2 -12 3 Discussion 12 4 -12 9 4Chapter...
Ngày tải lên: 30/09/2015, 05:52
Báo cáo y học: "Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells"
... level 3 3 3 2 1 (-) Under (+)Over + + + + + + + - Fold change 1. 92 2.39 4.96 2 .16 1. 85 2. 21 1.92 2.29 2 .17 0/+ 1. 91 Protein Bid Caspase-6 Caspase-8 Hsp90 Bax FADD Confidence level 1 1 0 (-) Under ... phosphor-specific, FADD, Fas/CD95/APO -1, GST-p, Hsp70, Hsp90, HspBP1, JNK (pT183/pY185) Phospho-Specific, JNK1, Ki67, JNK (pT183/pY185) phospho-specific, Nm23, PAI -1, pan-JNK/SAPK1, PARP, PCNA, PTEN, Rb, ... Pan-JNK/SAPK1-43kD TRADD Bag -1 Confidence level 0 0 0 (-) Under (+)Over + Fold change 0/+ 1. 08 1. 19 1. 23 1. 01 1.07 1. 22 No exp Fold change means a semiquantitative value that represents the general...
Ngày tải lên: 31/10/2012, 15:12
Báo cáo y học: " Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta
... inflammation J Clin Invest 19 99; 10 3: 17 5-83 [32] Cohn L, Tepper JS, Bottomly K IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells J Immunol 19 98; 16 1: 3 813 -6 [33] Randolph ... 20 01; 19 3: 13 27-32 [13 ] Hjelmstrom P, Fjell J, Nakagawa T, Sacca R, Cuff CA, Ruddle NH Lymphoid tissue homing chemokines are expressed in chronic inflammation Am J Pathol 2000; 15 6: 11 33-8 [14 ] ... positive cells) and dendritic cells (CD11c positive cells [37,38]) As shown in Figure 5, control, LTβ-KO, and plt mutant mice all showed similar accumulations of B220 positive B cells and CD11c positive...
Ngày tải lên: 03/11/2012, 11:24
Study on the Photolytic Mechanisms of Red 141 Dye Wastewaters with an 185nm Vacuum-UV lamp
... decomposition of Red 14 1 in VUV/H2O2 system Red 14 1 pH 1 θ2 θ3 θ4 28.06% 18 .99% 2. 51% 50.44% 25.56% 17 .00% 1. 56% 55.88% 24.55% 17 .19 % 1. 58% 56.68% 20.83% 29. 51% 2.82% 46.85% 11 28.65% 37. 91% 3.88% 29.55% ... the decomposition of Red 14 1 in VUV/O2 system Red 14 1 pH 1 η2 η3 56. 61% 38.32% 5.07% 57.93% 38.54% 3.53% 56.65% 39.68% 3.66% 39 .18 % 55. 51% 5. 31% 11 40.68% 53. 81% 5. 51% (2) VUV/H2O2 system Figure ... C/Co C/Co System :18 5UV/H2O2 Red1 41 Initial conc of Red1 41= 25mg/l Temp.=25.0±0.5 Red 14 1:H2O2 =1: 80 Rotation rate=750rpm 0.9 0.8 0.7 0.6 System :18 5UV/H2O2 Red1 41 Initial conc of Red1 41= 25mg/l Temp.=25.0±0.5...
Ngày tải lên: 05/09/2013, 09:08
ISOTOPE HYDROGRAPH SEPARATION FOR MODELING OF RUNOFF MECHANISMS OF ATMOSPHERICALLY DERIVED CHEMICAL AND RADIOACTIVE POLLUTANTS
... load ( g/km2 ) * Element MLtotal MLold MLnew 3 25.7 x10 0.3 x10 Na 26 x10 3 41 x10 ( < x10 ) Si 41 x10 Cr 0.4 0.34 0.06 Cu 3.2 1. 5 1. 7 Sb 0 .19 0 .12 0.07 runoff (mm) 5.6 5.3 0.3 * The load is normalized ... Earth-Science Reviews, Vol 57, 12 5 -17 6 Harris, D M., McDonnel,l J J (19 95) Hydrograph separation using continuous open system isotope mixing Water Res Res., Vol. 31, No .1, 15 7 -17 1 Horita, J and Kendall, ... following equation (Kendall and Caldwell, 19 98): δ = {(Rsample/Rstandard) -1} 10 00, where R refers to the ratio of 2H/1H, or 18 O /16 O in atomic concentrations - 244 - (1) Journal of Water and Environment...
Ngày tải lên: 05/09/2013, 09:08
Mechanisms of Unstable Nitrite Inhibition of Aerobic Phosphate Uptake
... Environment Technology, Vol 6, No .1, 2008 Anoxic Phoaphate Uptake Rate -1 -1 (mgP gVSS h ) 30 25 20 15 10 0 Aerobic Nitrite Consumption Rat (mgN gVSS -1 h -1 ) 10 e Figure – Relationship between ... polyphosphate-accumulating organisms and design of 16 S rRNA-directed probes for their detection and quantitation Appl Environ Microb., 66, 11 75 11 82 Hascoet, M.C and Florentz, M., (19 85) Influence of nitrates on ... biological phosphorus removal from wastewater Water SA, 11 (1) , 1- 8 Hesselmann, R.P.X., Werlen, C., Hahn, D., van der Meer, J R and Zehnder, A J B (19 99) Enrichment, phylogenetic analysis and detection...
Ngày tải lên: 05/09/2013, 09:38
Transmission mechanisms of monetary policy the evidence
... investment spending • Interest-rate effects are only one of many channels Real and Nominal Interest Rates (T-bills) 19 31- 2009 Early Monetarist Evidence on the Importance of Money • Money growth ... Policy Traditional Interest-Rate Channels: expansionary monetary policy ir ↓, I ↑, Y↑ The interest rate channel of monetary transmission applies equally to C Also, it places emphasis on ir rather ... thereby stimulating production Also, an ↑ in housing and land prices ↑ W, thereby ↑ C & Y Credit View This view proposes that two types of monetary transmission channels arise as a result of information...
Ngày tải lên: 05/01/2014, 17:01
Tài liệu Women''''s attitudes towards mechanisms of action of family planning methods: survey in primary health centres in Pamplona, Spain doc
... (33 .1) 5 81 (10 0) 325 (56.3) 79 (13 .7) 17 3 (30) 5 81 (10 0) CI 95% (42 .1 50.4) (14 .8– 21. 3) (14 .7– 21. 1) (15 – 21. 4) (20.9–28 .1) (54.5–62.7) (13 .9–20.2) (34.4–42.5) (35.4–43.6) (18 .8–25.7) (11 .7 17 .6) ... 394 (10 0) 12 2 ( 21. 1) 455 (78.9) 577 (10 0) 338 (58.2) 12 1 (20.8) 92 (15 .8) 30 (5.2) 5 81 (10 0) 260 ( 91. 6) 20 (7) (1. 4) 284 (10 0) 11 7 (20 .1) 287 (49.4) 16 0 (27.5) 17 (3) CI 95% (90–94.4) (5.6 10 .1) ... (46.3) 10 3 (18 ) 10 2 (17 .7) 10 4 (18 ) 575 (10 0) 14 1 (24.3) 33 (58.7) 98 (17 ) 578 (10 0) 222 (38.4) 228 (39.4) 12 8 (22.2) 578 (10 0) 84 (14 .5) 330 (57) 16 5 (28.5) 579 (10 0) 205 (35.3) 18 3 ( 31. 6) 19 2...
Ngày tải lên: 13/02/2014, 06:20
Tài liệu Báo cáo khoa học: Mechanisms of amyloid fibril formation – focus on domain-swapping doc
... Jaskolski M (2005) 3D domain-swapped human FEBS Journal 278 (2 011 ) 2263–2282 ª 2 011 The Authors Journal compilation ª 2 011 FEBS ˇ E Zerovnik et al 15 4 15 5 15 6 15 7 15 8 15 9 16 0 16 1 16 2 16 3 16 4 16 5 16 6 ... 278 (2 011 ) 2263–2282 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 2279 ˇ E Zerovnik et al Domain-swapping and amyloid fibril formation 12 7 12 8 12 9 13 0 13 1 13 2 13 3 13 4 13 5 13 6 13 7 13 8 13 9 and ... the Domain-swapping and amyloid fibril formation 11 6 11 7 11 8 11 9 12 0 12 1 12 2 12 3 12 4 12 5 12 6 aged Virchows Arch A Pathol Anat Histopathol 423, 18 5 19 4 Lalioti MD, Mirotsou M, Buresi C, Peitsch MC,...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Survival mechanisms of pathogenic Mycobacterium tuberculosis H37Rv ppt
... [65] 10 11 12 13 14 15 16 aceA mceD cmaA, mmaA4 sigE ⁄ sigH Acr drrC – erp ideR glnA aphC KatG fadD26 fadD28 fbpa PKnG [66] [67] [68] [42] [54] [69] [70] [ 71] [72] [73] [74] [75] [76] 17 18 19 ... Function References Rv0467 Rv 017 0 Rv3392c ⁄ Rv0503c ⁄ Rv0642c Rv12 21 ⁄ Rv3223c Rv2031c Rv2938 Rv3 718 c Rv3 810 Rv2 711 Rv2220 Rv2428 Rv1908c Rv2930 Rv29 41 Rv3804c Rv0 410 c Isocitrate lyase ⁄ dormancy ... partition Mol Microbiol 41, 10 37 10 51 Trach K & Hoch JA (19 89) The Bacillus subtilis spo0B stage sporulation operon encodes an essential GTP-binding protein J Bacteriol 17 1, 13 62 13 71 Maddock J, Bhatt...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx
... Endocrinol Metab 85, 2839–2853 11 7 Wang C, Cunningham G, Dobs A, Iranmanesh A, Matsumoto AM, Snyder PJ, Weber T, Berman N, 5766 11 8 11 9 12 0 12 1 12 2 12 3 12 4 12 5 12 6 12 7 Hull L & Swerdloff RS (2004) ... function [10 8– 11 1] Testosterone therapy in men with androgen deficiency demonstrated an improvement in erectile function [11 2 11 4] and increased muscle mass and decreased visceral fat [11 5 12 1] Furthermore, ... of erectile dysfunction in older men J Urol 17 6, 15 19 15 23 Larsen SH, Wagner G & Heitmann BL (2007) Sexual function and obesity Int J Obes 31, 11 89 11 98 Diaz-Arjonilla M, Schwarcz M, Swerdloff...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions pdf
... Biochem 11 6, 595–600 19 Thauer RK, Jungermann K & Decker K (19 77) Energyconservation in chemotropic anaerobic bacteria Bacteriol Rev 41, 10 0 18 0 20 Nakanishi I, Itoh S & Fukuzumi S (19 99) Electrontransfer ... Barletta G & Jordan F (19 96) Intramolecular model for the reductive acyl transfer catalyzed by alpha-keto acid dehydrogenases J Am Chem Soc 11 8, 11 026 11 029 Pan K & Jordan F (19 98) D,L-S-methyllipoic ... Schleifer KH & Gotz F (19 84) Purification ¨ and biochemical-characterization of pyruvate oxidase from Lactobacillus plantarum J Bacteriol 16 0, 273–278 11 Williams FR & Hager LP (19 61) A crystalline...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters pdf
... ND (< 1) 2.8 ND (> 3) LA 9 .1 1. 9 ND (< 1) >1 HA 0.8 0.2 0.4 5.5 14 LA NDa ND (> 1) >1 HCI 1. 7 0.5 1. 9 1. 2 0.6 0.3 0.3 0.3 LCI 12 .5 0 LCI 7.7 0.2 ) LCI 7.9 0.4 0 PCI b 0 .18 0.02 ... dyes for wild-type BuChE [48], 40 [S]/n 30 20 10 10 12 14 16 [Serotonin] mM 10 12 14 16 [Serotonin] mM 10 000 4000 3500 S = o-NAC 8000 3000 2500 [S]/n 1/ n (A 430nm), Effects of benzalkonium on o-NPA ... activitiy A aKi Vmax 1 bVmax ẳ ỵ Dslope Km a bị ẵL Km a bị 7000 0.005 6000 5000 0.00 0.00 0.0 01 4000 10 10 20 1/ [benzalkonium] àM 3000 2000 Dintercept ẳ wild type 10 00 10 1/ [ATMA] mM 11 ị aKi Vmax bVmax...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... excluding the partici- 1. 396 (1. 3 71) {1. 392} 1. 897 (2.039) {1. 898} 1. 743 (1. 716 ) {1. 750} 1. 463 {1. 485} 1. 462 {1. 499} 2. 412 (2.5 01) {2. 413 } 1. 944 {1. 882} 4TS1-IV (2TS1-IV) {4TS1-III} 2.465 {2.523} ... superoxo-ferrous state 15 6 15 7 15 8 15 9 16 0 16 1 16 2 16 3 16 4 16 5 16 6 16 7 16 8 16 9 17 0 17 1 17 2 in a reduced oxy-ferrous hemoprotein and model compounds J Am Chem Soc 12 5, 16 34 016 346 Leibl, W., Nitschke, ... Shiro, Y (2002) Enzymatic 4354 P Hlavica (Eur J Biochem 2 71) 10 3 10 4 10 5 10 6 10 7 10 8 10 9 11 0 11 1 11 2 11 3 11 4 11 5 11 6 11 7 11 8 reaction of hydrogen peroxide-dependent peroxygenase cytochrome P450s: kinetic...
Ngày tải lên: 19/02/2014, 16:20